Best Natrol Aids in 2026

Daisy
Last Updated: Feb 25, 2026

At a Glance: Our Top Picks for Natrol Aids

Unisom SleepTabs, Nighttime Sleep-aid, Doxylamine Succinate, 32 Tablets
#TOP1
Unisom Sleeptabs, Nighttime Sleep-Aid, Doxylamine Succinate, 32 Tablets
9.8
PM SCORE
Unisom Quick Sleepmelts Night Time Sleep Aid, Cherry,24 Count (Pack of 4)
#TOP2
Unisom Quick Sleepmelts Night Time Sleep Aid, Cherry,24
9.7
PM SCORE
Unisom Sleep Gels, Nighttime Sleep-Aid, 50 mg Diphenhydramine HCl, 60 Soft Gel Capsules
#TOP3
Unisom Sleep Gels, Nighttime Sleep-Aid, 50 Mg Diphenhydramine
9.7
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Natrol Aids of 2026

Unisom Sleeptabs, Nighttime Sleep-Aid, Doxylamine Succinate, 32 Tablets

UNISOM
CHATTEM136705
1.75 X 3.06 X 3.13 Inches
0.01 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Alef Beis 9.95

Features

INCLUDES: One (1) 32-count bottle of Unisom SleepTabs Nighttime Sleep-aid; one tablet per dose

FALL ASLEEP 33% FASTER*: Effective sleep aid helps you fall asleep faster* and stay asleep *versus placebo in a clinical study

NON-HABIT FORMING: SleepTabs are safe if used as directed, non-habit forming and help you sleep through the night and feel recharged without grogginess or lingering side effects

TRUST UNISOM, THE SLEEP EXPERT: The #1 Pharmacist Recommended OTC Sleep-Aid Brand* *Data represents brand/product selections from the 2019 Pharmacy Times Survey of Pharmacists' OTC Recommendations

FIND A NIGHTTIME SLEEP SOLUTION RIGHT FOR YOU: Millions of people turn to Unisom for a restful night's sleep; Unisom SleepGels, SleepTabs, SleepMinis, SleepMelts or PM Pain can help you take on your day

#TOP2

Unisom Quick Sleepmelts Night Time Sleep Aid, Cherry,24 Count (Pack Of 4)

UNISOM
PPAX1225705
6.00 X 6.00 X 8.00 Inches
0.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Authentic & Genuine 8.70

Features

Item Package Length: 8.2cm

Item Package Width: 10.4cm

Item Package Height: 14.8cm

Item Package Weight: 0.139kg

Unisom Sleep Gels, Nighttime Sleep-Aid, 50 Mg Diphenhydramine Hcl, 60 Soft Gel Capsules

UNISOM
UNI-4403
1.81 X 3.06 X 3.50 Inches
0.13 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

TRUSTED SLEEP SUPPORT: Unisom Sleep Gels are clinically proven to help you fall asleep 33% faster. Sleep through the night & wake up recharged in the morning without grogginess or other side effects.

SLEEP SOUNDLY & WAKE UP ENERGIZED: After a stressful day, every minute of sleep matters. Unisom helps reduce your natural urge to stay awake, helping you fall asleep faster & get the rest you need.

RECHARGE TONIGHT: When stress gets in the way of a restful night, you need a sleep aid that can help you fall asleep & wake up refreshed. Choose Unisom, the #1 pharmacist recommended OTC sleep aid.

EVERYTHING YOU NEED, NOTHING YOU DON'T: Unlike some OTC brands, Unisom offers single active ingredient sleep-aids. If all you need is a great night's sleep, skip the extra medicine & reach for Unisom.

THE UNISOM ADVANTAGE: Millions of people turn to Unisom for safe, non-habit forming relief. Available in softgels, tablets, melts, mini-capsules, & liquid form, Unisom has a sleep aid for everyone.

Rxzell Sleep Aid, Diphenhydramine Hcl 50Mg, 220 Softgels - Fall Asleep Faster, Deeper Restful Sleeping, Non Habit-Forming

RXZELL
RZDIPHEN50
2.25 X 2.25 X 4.50 Inches
0.37 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
stonydepot 9.93

Features

NIGHTTIME SLEEP-AID - one softgel before bed. Safe and non habit-forming. Helps you reach deeper, restful sleep at night.

SOFTGEL AT MAXIMUM STRENGTH - easy-to-swallow extra strength liquid filled softgels delivers maximum performance

ONE SOFTGEL PER DOSE - for adults and children over 12 years at bedtime, or as directed by a doctor or pharmacist

ACTIVE INGREDIENT - Diphenhydramine HCl 50mg sleeping pills. Relax your mind and body so you can fall asleep effortlessly

COMPARE TO - Unisom SleepGels in the active ingredient

Goodsense Nighttime Sleep-Aid Softgels, Diphenhydramine Hcl 50 Mg, Relieves Occasional Sleeplessness, 32 Count

GOODSENSE
5V664
1.78 X 3.44 X 1.78 Inches
0.09 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: The active ingredient in GoodSense Nighttime Sleep Aid softgels is diphenhydramine HCl 50 mg. Compare to the active ingredient of Unisom SleepGels.

USE: GoodSense Nighttime Sleep Aid relieves occasional sleeplessness with a non-habit forming sleep medication for adults for a restful night's sleep. Be ready for the challenges of a new day.

FOCUS ON SLEEP: Your day can be ruined if you lack sleep, have poor quality sleep or insufficient sleep. GoodSense Nighttime Sleep Aid softgels, with diphenhydramine HCl 50 mg as the active ingredient, relieve occasional sleeplessness.

NON-HABIT FORMING: GoodSense Nighttime Sleep Aid softgels contain diphenhydramine hydrochloride 50 mg, and are non-habit forming. Just one softgel in a single dose. Difficulty falling asleep or poor quality sleep can affect your day.

GLUTEN FREE: This is a gluten-free nighttime sleep aid, which is for adults and children ages 12 years and older to relieve occasional sleeplessness.

Welmate | Sleep Aid | Doxylamine Succinate 25Mg | Nighttime Sleep Aid | Safe & Effective | Non-Habit Forming | Sleep Aids For Adults & Children | For Women & Men | Made In Usa | 200 Tablets

WELMATE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
iOTC DEALS 9.95

Features

Maximum Strength Ingredients: Welmate Sleep Aid contains 25mg of Doxylamine Succinate, a leading nighttime sleep aid which compares to the active ingredient in Uni-som Sleep Tabs. Made in USA.

Solutions to Occasional Sleeplessness: Stress that is triggered by life changes related to work, school, health, finances, family, or trauma causes poor sleep habits. Take Welmate's Sleep Aid to help combat stress and normalize your sleep pattern.

Get a Better Night's Sleep: No next day grogginess. Improves the quality of your sleep. Wake up feeling refreshed and in a good mood, ready to seize the day.

Fall Asleep Faster: Take one tablet 30 minutes before bedtime to help you fall asleep faster. No more restless nights! Clinically tested and proven effective.

Perfect for Home & Travel: Use at home or on-the-go. Take Welmate's Sleep Aid when traveling to combat jet lag or timezone changes and feel energized during your trip. Whether in the air or in your armchair, let us help you fall asleep faster and stay asleep longer.

Safrel Nighttime Sleep Aid, Diphenhydramine Hcl 50Mg, 250 Softgels | Strong Non Habit-Forming Restful Sleeping Support For Men & Women | Fall Asleep Faster & Wake Up Refreshed

SAFREL
0.44 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Safrel 9.90

Features

YOUR BEST ALLY AGAINST OCCASIONAL SLEEPLESSNESS: Fight away unwanted insomnia and occasional sleeplessness that keep you awake at nights with the best Sleep Aid Softgels by Safrel. Packed with 50mg of Diphenhydramine HCL (comparable active ingredients to Unisom) each sleep pill will help you achieve a deeper state of relaxation that will lead to a faster, more restful and more rewarding sleep. Just what your tired body and stressed mind need!

NON-HABIT FORMING | A SAFE CHOICE FOR WHEN INSOMNIA STRIKES: The Safrel non-habit forming sleep relief pills can safely promote a better sleep quality when you need it the most, without affecting your body’s natural sleep routine. An excellent sleep help supplement to use with peace of mind when it’s harder to fall asleep, during overnight stays in different homes, with people with changing sleep schedules or those with pre-bed restlessness.

MORE RESTFUL SLEEP = A HAPPIER, MORE ENERGIZED & ACTIVE YOU: Our nighttime sleep aid softgels will not only help you fall asleep faster, but they also promote a deeper, more peaceful and utterly refreshing sleep circle. This way, you will wake up feeling well-rested, energized and ready to enjoy your day to the maximum. A great way to improve your performance and mood in the most natural way!

A MUST-HAVE ADDITION TO YOUR TRAVEL KIT, FOR YOU & YOUR FAMILY: Jet lag, different time zones and trying to sleep in a new bed can affect your natural sleep cycle. With these amazing sleeping softgels you can provide your body the little extra help it needs to fall asleep anywhere, anytime. Suitable for men, women and even kids 12 years old and above. Great also to take on planes, public transportation or any other noisy setting!

VALUE PACK OF 250 SOFTGELS | MADE IN THE USA| 100% SATISFACTION GUARANTEE: To provide unbeatable value, each bottle includes a whopping 250 maximum strength sleep aid softgels that are sure to last you for a long, long time. Widely tried and loved by thousands of happy customers and backed up by a 100% Money Back Satisfaction Guarantee, you have every good reason to try it out today!

#TOP8

Unisom Sleepmelts Cherry Flavor 24 Each (Pack Of 2)

UNISOM
PPAX1225705
6.00 X 6.00 X 10.00 Inches
0.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
JJF store 5.75

Features

INCLUDES: 24 count tablets per one (1) bottle of Unisom SleepMelts Nighttime Sleep-aid

NIGHTTIME AID: Cherry flavored tablets

DISSOLVES IN 30 SECONDS: Without water; Melt away your restless nights with quickly dissolving tablets

NON-HABIT FORMING: Safe when used as directed and non-habit forming; fall asleep fast, sleep soundly and wake refreshed

TRUST UNISOM, THE SLEEP EXPERT: #1 Pharmacist Recommended OTC Sleep-Aid Brand

#TOP9

Unisom Sleepminis, Nighttime Sleep-Aid, Diphenhydramine Hci 25 Mg, Mini-Capsules, 60 Count (Pack Of 6)

UNISOM
041167006702
1.69 X 3.00 X 3.25 Inches
0.09 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

INCLUDES: Six (6) bottles with 60 Mini-Capsules of Unisom SleepMinis Nighttime Sleep-aid; two mini-capsules per dose

A STRESSFUL DAY DESERVES A RESTFUL NIGHT: SleepMinis are small and easy to swallow, helping you fall asleep fast for a good night's sleep to recharge and restore Compared to other leading OTC sleep-aids

NON-HABIT FORMING: SleepMinis are safe if used as directed, non-habit forming and help you sleep soundly

TRUST UNISOM, THE SLEEP EXPERT: The #1 Pharmacist Recommended OTC Sleep-Aid Brand Data represents brand/product selections from the 2019 Pharmacy Times Survey of Pharmacists' OTC Recommendations

FIND A NIGHTTIME SLEEP SOLUTION RIGHT FOR YOU: Millions of people turn to Unisom for a safe night's sleep; Unisom SleepGels, SleepTabs, SleepMinis, SleepMelts or PM Pain can help you take on your day.

Unisom Sleepmelts, Nighttime Sleep-Aid, Diphenhydramine Hci, 24 Tablets, 25Mg

UNISOM
B002CVV1JY
1.38 X 3.00 X 3.88 Inches
0.10 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

INCLUDES: One (1) 24-count bottle of Unisom SleepMelts Nighttime Sleep-aid; two tablets per dose

DISSOLVES IN 30 SECONDS WITHOUT WATER: Melt away your restless nights with quickly dissolving Unisom tablets

NON-HABIT FORMING: Cherry-flavored SleepMelts are safe if used as directed and non-habit forming; fall asleep fast, sleep soundly and wake refreshed

TRUST UNISOM, THE SLEEP EXPERT: The #1 Pharmacist Recommended OTC Sleep-Aid Brand* *Data represents brand/product selections from the 2019 Pharmacy Times Survey of Pharmacists' OTC Recommendations

FIND A NIGHTTIME SLEEP SOLUTION RIGHT FOR YOU: Millions of people turn to Unisom for a restful night's sleep; Unisom SleepGels, SleepTabs, SleepMinis, SleepMelts or PM Pain can help you take on your day.

Top 10 aids Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Unisom 6
Goodsense 1
Rxzell 1
Safrel 1
Welmate 1

Top 10 aids Brands Pie Chart


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