Best Major Pharmaceuticals Antacids in 2026

Daisy
Last Updated: Jul 18, 2026

At a Glance: Our Top Picks for Major Pharmaceuticals Antacids

OmepraCare DR Tablets Omeprazole 20mg Acid Reducer for Heartburn, (14 Tablets/Bottle) One 3-Pack Carton for Three 14-Day Courses, Delayed-Release Tablets (84ct (2 Pack))
#TOP1
Omepracare Dr Tablets Omeprazole 20Mg Acid Reducer For
10.0
PM SCORE
Kirkland Signature Chewable Ultra Strength Antacid / Calcium SUpplement 1000mg 265 Count (Pack of 2)
#TOP2
Kirkland Signature Chewable Ultra Strength Antacid / Calcium
9.8
PM SCORE
Major Pharmaceuticals Acid Gone Antacid Liquid, Flavor, 12 Assorted Spearmint 12 Fl Oz (Pack of 4)
#TOP3
Major Pharmaceuticals Acid Gone Antacid Liquid, Flavor, 12
9.2
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Major Pharmaceuticals Antacids of 2026

Omepracare Dr Tablets Omeprazole 20Mg Acid Reducer For Heartburn, (14 Tablets/Bottle) One 3-Pack Carton For Three 14-Day Courses, Delayed-Release Tablets (84Ct (2 Pack))

OMEPRACARE DR
SB-123
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Aytu Consumer Health 9.95

Features

The active ingredient is Omeprazole 20 mg, an acid reducer used to help with frequent heartburn relief (Compare to Prilosec OTC)

OmepraCareDR 20 mg Omeprazole tablets help with frequent heartburn relief that occurs 2 or more times a week

Take once every 24 hours for 14 days. Not intended for immediate relief of heartburn, may take 1 to 4 days for full effect

Heartburn Tips: There are many things you can do to help with uncomfortbale heartburn. When nothing else works, choose OmepraCareDR Omeprazole 20 mg

Kirkland Signature Chewable Ultra Strength Antacid / Calcium Supplement 1000Mg 265 Count (Pack Of 2)

KIRKLAND SIGNATURE
096619879021
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
P0ssum 7.48

Features

Chewable

Rich in calcium

Relief of acid indigestion & heartburn

Assorted berry flavors

265 tablets x 2

Major Pharmaceuticals Acid Gone Antacid Liquid, Flavor, 12 Assorted Spearmint 12 Fl Oz (Pack Of 4)

MAJOR PHARMACEUTICALS
00904772714
7.00 X 5.00 X 3.00 Inches
0.10 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Preferred Pharmacy Plus 9.94

Features

Relieves heartburn, acid indigestion, sour stomach, and upset stomach associated with these symptoms

Made with aluminum hydroxide and magnesium carbonate for fast acting relief

Keeps acid in the stomach where it belongs, Reduces the occurrence of acid reflux

Pack of 4 Bottles of 12 oz each. Total 48 oz Easy-to-swallow; Spearmint flavor

Major Pharmaceuticals 264978 Acid Gone Antacid Liquid, Compare To Gaviscon, 12 Oz. Volume, Spearmint, Light-Green

MAJOR PHARMACEUTICALS
264978
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Royal Meds 9.95

Features

Product Type: Professional Healthcare

Package Dimensions: 10" L X 9" W X 10" H

Package Weight: 0.9 Pounds

Country Of Origin: United States

Rite Aid Acid Reducer Omeprazole Delayed Release Tablets - 20 Mg, 3 Bottles, 14 Count Each (42 Count Total) - Heartburn Relief - Heartburn Medicine - Treats Frequent Heartburn

RITE AID
0357353
0.01 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Rite Aid, Inc. 9.98

Features

TREAT HEARTBURN: Rite Aid Acid Reducer Omeprazole Delayed Release Tablets treats frequent heartburn (occurring 2 or more days a week). It is not intended for the immediate relief of heartburn; Rite Aid Acid Reducer may take 1 to 4 days for full effect. This pack contains 42 tablets total: three 14-day courses of treatment offering heartburn relief through delayed-release tablets.

OMEPRAZOLE 20 MG: Compare Rite Aid’s heartburn medicine to the active ingredient in top brands. Get all the benefits of this effective heartburn medicine with Rite Aid. Omeprazole is used to treat certain stomach and esophagus problems, such as acid reflux and heartburn. It works by reducing the amount of acid your stomach makes. This acid reducer relieves symptoms such as heartburn and reduces the effects of acid reflux.

EASY-TO-SWALLOW TABLETS: These tablets are designed for easy swallowing. Each caplet contains 20 mg of Omeprazole. The inactive ingredients are carnauba wax, ferric oxide red, ferric oxide yellow, hypromellose, hypromellose acetate succinate, lactose monohydrate, monoethanolamine, propylene glycol, sodium lauryl sulfate, sodium starch glycolate, sodium stearate, sodium stearyl fumarate, talc, titanium dioxide, and triethyl citrate.

14-DAY COURSE OF TREATMENT: Adults 18 years of age and older: Swallow 1 tablet with a glass of water before eating in the morning; take every day for 14 days; do not take more than 1 tablet a day; do not crush the tablets into food; and do not use for more than 14 days unless directed. This product is meant to be used once a day (every 24 hours) for 14 days. It may take 1 to 4 days to reach full effect, although some people get complete relief of symptoms within 24 hours.

RITE AID VISION & MISSION: Our vision at Rite Aid is for customers to confidently choose us first for their everyday health and wellness needs because we consistently understand and exceed their expectations. Our mission is to improve the health and wellness of our communities through engaging experiences that provide our customers with the best products, services, and advice for their unique needs.

Major Pharmaceuticals 700343 Calcium Antacid Tablet, Compare To Tums, Mixed Fruit (Pack Of 150)

MAJOR PHARMACEUTICALS
700343
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Model Number: 700343

Product Type: Professional Healthcare

Package Quantity: 1

Country Of Origin: United States

Top 10 antacids major pharmaceuticals Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Major Pharmaceuticals 3
Kirkland Signature 1
Omepracare Dr 1
Rite Aid 1

Top 10 antacids major pharmaceuticals Brands Pie Chart


We've carried out a comprehensive analysis of 14,406 reviews on antacids major pharmaceuticals, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select antacids major pharmaceuticals priced around $19.45, with top brands including major pharmaceuticals, aidance, sera, skin set go, omepracare dr, revitale, superbobi, kirkland signature and voltaren and rite aid

Our team of expert editors reviewed these high-quality items and handpicked the top 6 antacids major pharmaceuticals for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include preferred pharmacy plus, amazon.com, royal meds, creative consumer products, skin set go®, aytu consumer health, general-healthcare, pharmco and r&dog and p0ssum .

We are dedicated to assisting our users in finding the right antacids Products based on their needs, saving them considerable time when choosing which antacids major pharmaceuticals to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.