Best Creams Cortisone Treatments in 2025

Daisy
Last Updated: Nov 5, 2025

At a Glance: Our Top Picks for Creams Cortisone Treatments

Gold Bond Medicated Talc-Free Original Strength Body Powder 10 oz., Cooling, Absorbing, Itch Relief
#TOP1
Gold Bond Medicated Talc-Free Original Strength Body Powder
9.8
PM SCORE
First Aid Only 18-012 Hydrocortisone Anti-Itch Cream Packet (Box of 12)
#TOP2
First Aid Only 18-012 Hydrocortisone Anti-Itch Cream Packet
9.8
PM SCORE
Amazon Basic Care Hydrocortisone 1% Anti-itch Cream, Intensive Healing Formula, 1 Fluid Ounce
#TOP3
Amazon Basic Care Hydrocortisone 1% Anti-Itch Cream, Intensive
9.8
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Creams Cortisone Treatments of 2025

Gold Bond Medicated Talc-Free Original Strength Body Powder 10 Oz., Cooling, Absorbing, Itch Relief

GOLD BOND
041167011096
4.00 X 2.38 X 7.38 Inches
0.63 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Contains: One (1) 10-oz. bottle of Gold Bond Medicated Body Powder Original Strength

Unique Triple Action Relief: This Gold Bond Medicated Body Powder cools, absorbs moisture and relieves itch

Relieves Itch: This body powder temporarily relieves pain and itching associated with minor cuts and burns, scrapes, insect bites and more

Itch Relieving Menthol: Contains 0.15% menthol to temporarily relieve itch

When to Apply: Apply after showering or exercising to keep you cool, dry, and comfortable

First Aid Only 18-012 Hydrocortisone Anti-Itch Cream Packet (Box Of 12)

FIRST AID ONLY
18-012
2.25 X 0.75 X 4.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Contains 12 single-use tamper evident foil Hydrocortisone Anti-Itch packets

Convenient anti-itch cream packets

Perfect for standalone first aid or as a refill for a kit

Contents inside box may be substituted with equivalent products in different brand names

Amazon Basic Care Hydrocortisone 1% Anti-Itch Cream, Intensive Healing Formula, 1 Fluid Ounce

AMAZON BASIC CARE
1.06 X 1.50 X 5.75 Inches
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: The active ingredient in this anti-itch cream is hydrocortisone 1 percent; compare to the active ingredient in Cortizone 10 Intensive Healing Formula

MAXIMUM STRENGTH RELIEF: Hydrocortisone is the number one doctor recommended anti-Itch active Ingredient (of U.S. physicians surveyed by an independent market research firm)

POWERFUL MEDICINE, FAST RELIEF: Great for relieving itching associated with skin irritation, rashes, inflammation, redness, insect bites, eczema, psoriasis and poison ivy, oak and sumac

LASTS UP TO 10 HOURS when used as directed; ultra creamy, maximum strength hydrocortisone formula helps heal problem skin; safe for sensitive skin; for adults and children age 2 years of age and older

INTENSIVE HEALING FORMULA calms, nourishes and hydrates; clinically proven to moisturize for up to 24 hours; features antioxidants, chamomile and Vitamins A, C and E

Scalpicin Scalp Itch Relief, 1.5 Fl Oz. Maximum Strength (Pack Of 2)

SCALPICIN
317561
6.00 X 5.00 X 4.00 Inches
0.22 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
OTBrands 9.89

Features

America's #1 scalp itch medicine

Fragrance free, greaseless formula

Won't interfere with the way your hair looks and feels

With 1% hydrocortisone, the clear, non-greasy liquid is fast acting and easy to use

Preparation H Soothing Relief Anti Itch Cream, 1% Hydrocortisone Cream For Butt Itch Relief - 0.9 Oz Tube

PREPARATION H
1.38 X 2.13 X 5.44 Inches
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

One 0.9 ounce tube of Preparation H Soothing Relief Anti Itch Cream, 1% Hydrocortisone Cream

Maximum strength butt itch cream for adults, available without a prescription

Smooth, fragrance free itching cream that is pleasant and easy to use

Apply this anal itching product up to four times daily to relieve symptoms

Using Preparation H Soothing Relief Cleansing & Cooling Wipes before applying this anal itch cream helps to cool, soothe and cleanse before treating your itching

Zeasorb Prevention, 2.5 Oz

ZEASORB
303160233258
1.50 X 2.75 X 5.00 Inches
0.16 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Helps prevent excess moisture

Soothes chafing

Soothes itching

Scalpicin Scalp Itch Relief, 1.5 Fl Oz. Maximum Strength (Pack Of 2)

SCALPICIN
9170484
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Dave Deals 9.94

Features

America's #1 scalp itch medicine

Fragrance free, greaseless formula, contains Salicylic acid 3% Anti-Dandruff Liquid

Helps relieve scalp itch associated with: psoriasis; seborrheic dermatitis; eczema

Enhanced formula helps improve scalp condition and makes hair easier to comb.

Won't interfere with the way your hair looks and feels

Scalpicin Max Strength Scalp Itch Treatment, 1.5 Oz(Pack Of 3)

SCALPICIN
5400
6.00 X 4.00 X 4.00 Inches
0.07 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
OTBrands 9.89

Features

America's 1 scalp itch medicine

Fragrance free, greaseless formula, With 1% hydrocortisone, the clear, non-greasy liquid is fast acting and easy to use

Helps relieve scalp itch associated with: psoriasis; seborrheic dermatitis; eczema

Enhanced formula helps improve scalp condition and makes hair easier to comb.

Won't interfere with the way your hair looks and feels

#TOP9

Audiologists Choice Anti-Itch Cream

AUDIOLOGIST'S CHOICE
00401
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Emtech Labs 5.86

Features

Stops itchy ears

1-percent hydrocortisone cream

Scalpicin Scalp Itch Relief, 1.5 Fl Oz. Maximum Strength

SCALPICIN
363824054001
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
PrimeLoop 6.77

Features

America's #1 scalp itch medicine

Fragrance free, greaseless formula, contains Salicylic acid 3% Anti-Dandruff Liquid

Helps relieve scalp itch associated with: psoriasis; seborrheic dermatitis; eczema

Enhanced formula helps improve scalp condition and makes hair easier to comb.

Won't interfere with the way your hair looks and feels

Top 10 cortisone treatments creams Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Scalpicin 4
Amazon Basic Care 1
Audiologist's Choice 1
First Aid Only 1
Gold Bond 1
Preparation H 1
Zeasorb 1

Top 10 cortisone treatments creams Brands Pie Chart


We've carried out a comprehensive analysis of 25,320 reviews on cortisone treatments creams, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select cortisone treatments creams priced around $11.94, with top brands including preparation h, cortizone 10, gold bond, scalpicin, amazon basic care, sunmark, natureplex, solodate and yoeu naturals and exederm

Our team of expert editors reviewed these high-quality items and handpicked the top 10 cortisone treatments creams for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, betty bet, dave deals, herbsdaily, premier prime outlet, generic giant, yoeu naturals, silverrod pharmacy and otbrands and ebanel .

We are dedicated to assisting our users in finding the right treatments Products based on their needs, saving them considerable time when choosing which cortisone treatments creams to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.