Best Dental Topical Anesthetics in 2026

INSTANT PAIN RELIEF: Instant oral pain relief for mouth and gum irritation due to toothaches, canker sores, sore gums, denture pain, and minor dental procedures. Use with dentures to relieve discomfort.

MAXIMUM STRENGTH: Instant relief that takes you from ouch to ahhh! So, oral pain doesn’t hold you back. Formulated with 20% Benzocaine to offer maximum strength pain relief and instantly soothe mouth pain and dental irritation

EASY TO USE: Cut the Tube Tip for easy access to the oral pain relief you need; Adults and children 2 years and over. Not for use in children under 2 years of age.

Effective joint & muscle relief: Penetrex is the whole-body homeopathic therapy cream you’ve been waiting for. Trusted by over 2 million sufferers, Penetrex offers a different kind of relief.

The Penetrex difference: Our proprietary blend of natural ingredients leverages the homeopathic power of arnica, vitamin B6 and MSM to penetrate deeply, eliminating joint and muscle discomfort at the source.

The premium experience in muscle recovery: Penetrex is a non-greasy, non-sticky, non-staining, paraben-free, cruelty-free and vegan soothing cream without the burn, freeze or strong odor of other relief products.

INSTANT PAIN RELIEF: Instant pain relief with Orajel’s unique 4X clinical strength formula to help relieve pain of the tooth and gums

4X ACTIVE INGREDIENTS: With 4 active ingredients, Orajel Cream provides fast acting and maximum strength relief when you need it most

KILLS HARMFUL BACTERIA: Unique formula is designed to help kill harmful bacteria in the mouth, and can help to prevent infections

INSTANT PAIN RELIEF: Orajel Mouth Sore Gel contains 20% Benzocaine to relieve pain from canker sores, mouth sores, cold sores and other mouth irritations

SOOTHING RELIEF: Maximum strength gel uses menthol to soothe irritated and sore gums quickly, where you need it most

PROTECTION: Our unique, fast acting, formula contains an astringent to help protect sores from irritation, including irritation from dentures or braces, as well as canker sores

INSTANT PAIN RELIEF: Instant pain relief with Orajel’s maximum strength formula to help relieve pain of the tooth and gums with 20% benzocaine

KILLS HARMFUL BACTERIA: Unique formula is designed to help kill harmful bacteria in the mouth, and can help to prevent infections

COOLING RELIEF: To help relieve gum irritation, Orajel toothache gel contains cooling relief

HurriCaine Topical Anesthetic Gel Watermelon - 1 oz.

The Complete Solution for canker sores and other sores in the mouth

Maximum-strength pain medication (benzocaine) for fast temporary pain relief

Forms a long-lasting barrier to protect sores from further irritation

Finafta is created to provide temporary relief for your mouth and gums. It will help you to promote rapid healing of canker sores.

Finafta Oral Analgesic will assist you in getting rid of cold sores. You can feel how the affected area numbs on contact!

Our fantastic formula is developed with fluid extract of Rhubarb base with 60% Ethyl Alcohol. Fast relief for the gums and mouth!

MOUTH SORE TREATMENT: Rite Aid Max Strength Oral Liquid Anesthetic Benzocaine 20% pain relieving liquid temporarily relieves pain associated with toothaches, sore gums, mouth sores, canker sores, dentures/braces, cheek bites, and minor dental procedures.

FAST-ACTING PAIN RELIEF: Rite Aid offers instant relief from pain associated with toothaches, gum pain, canker sores, and dentures/braces. Compare Rite Aid to the leading national brand and get the same reliable mouth pain relief you can count on.

MAXIMUM STRENGTH: Formulated with 20% Benzocaine, Rite Aid Maximum Strength Liquid Anesthetic Oral Pain Relief offers the maximum amount of pain relief and aims to temporarily relief the mouth and tooth pain that ails you, so you can live pain free.

Instant Oral Pain Relief: Anbesol Maximum Strength Liquid for mouth pain, including toothache pain, canker sores, sore gums, mouth sores, denture pain, braces, retainer and aligner pain, and minor dental procedures

Ow to Wow! Instantly formulated with the active ingredient Benzocaine, an oral pain reliever, and numbs instantly to temporarily relieve toothaches, gum pain, canker sores and aligner pain.

Liquid Formula: Anbesol Liquid Formula goes on clear and is undetectable, stays where you apply it, and provides fast and effective numbing of oral pain