Best Paleo Digestive Supplements in 2026

LOW-FLUSH NIACIN: Each Endur-Acin tablet contains 250mg of niacin as nicotinic acid (vitamin B-3) in a vegetable wax matrix (tablet core) for an extended release over 6-8 hours.

HEART HEALTH AND CHOLESTEROL BALANCE: Backed by clinical research and may help maintain healthy cholesterol levels within the normal range.*

OPTIMAL ABSORPTION & MAXIMUM EFFECTIVENESS: The proprietary vegetable-based wax matrix melts at body temperature to slowly release nutrients over 6-8 hours, mimicking how your body processes food. This minimizes side effects and digestive upset.*

L-ARGININE 350mg SUSTAINED RELEASE is an advanced dietary supplement for adults interested in overall cardiovascular health, immune health, detoxification, protein synthesis, hormone regulation, male fertility, and more. Ideal for athletes.*

SUPPORTS VASCULAR HEALTH & HEALTHY BLOOD PRESSURE: The amino acid L-Arginine is critical for vascular health. Your endothelium (the layer of cells that line your blood vessels) relies on this amino acid for a healthy production of nitric oxide, which plays a key role in vascular health.*

4-6 HOUR SUSTAINED RELEASE: Endurance Products Company’s sustained-release tablet technology slowly releases nutrients over 4-6 hours, mimicking how your body processes food for optimal absorption and maximum effectiveness. This minimizes side effects and digestive upset.*

PANTETHINE FROM PANTESIN SUSTAINED RELEASE (SR) features Pantesin, a highly absorbable form of the B vitamin pantethine (B5), backed by clinical research and over 30 years of safe and effective use in Japan for heart health.*

PANTETHINE FROM PANTESIN (SR) works by providing a key building block for Coenzyme A, your body’s most active metabolic enzyme. CoA is required to activate a wide variety of biochemical reactions critical for whole body health. It plays a central role in converting food into cellular energy.

5-7 HOUR SUSTAINED RELEASE: Endurance Products Company’s sustained-release tablet technology slowly releases nutrients over 5-7 hours, mimicking how your body processes food for optimal absorption and maximum effectiveness. This minimizes side effects and digestive upset.*

L-ARGININE 350mg SUSTAINED RELEASE is an advanced dietary supplement for adults interested in overall cardiovascular health, immune health, detoxification, protein synthesis, hormone regulation, male fertility, and more. Ideal for athletes.*

SUPPORTS VASCULAR HEALTH & HEALTHY BLOOD PRESSURE: The amino acid L-Arginine is critical for vascular health. Your endothelium (the layer of cells that line your blood vessels) relies on this amino acid for a healthy production of nitric oxide, which plays a key role in vascular health.*

4-6 HOUR SUSTAINED RELEASE: Endurance Products Company’s sustained-release tablet technology slowly releases nutrients over 4-6 hours, mimicking how your body processes food for optimal absorption and maximum effectiveness. This minimizes side effects and digestive upset.*

FREE OF COMMON ALLERGENS: Vegan/Vegetarian safe. No milk, egg, fish, shellfish, tree nuts, peanuts, wheat, corn, yeast, or soy. Gluten-free. No salt, sugar, starch, artificial flavorings, or preservatives.

FREE OF COMMON ALLERGENS: Vegan/Vegetarian safe. No milk, egg, fish, shellfish, tree nuts, peanuts, wheat, corn, yeast, or soy. Gluten-free. No salt, sugar, starch, artificial flavorings, or preservatives.

FREE OF COMMON ALLERGENS: Vegan/Vegetarian safe. No milk, egg, fish, shellfish, tree nuts, peanuts, wheat, corn, yeast, or soy. Gluten-free. No salt, sugar, starch, artificial flavorings, or preservatives.