Best Vegetarian Enzyme Supplements in 2026

Daisy
Last Updated: Jul 17, 2026

At a Glance: Our Top Picks for Vegetarian Enzyme Supplements

Solgar Yeast-Free Selenium 200 mcg, 100 Tablets - Supports Antioxidant & Immune System Health - Non-GMO, Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings
#TOP1
Solgar Yeast-Free Selenium 200 Mcg, 100 Tablets -
9.8
PM SCORE
Solgar Vitamin K2 (MK-7) 100mcg, 50 Vegetable Capsules - Supports Bone Health - Natural Whole Food Source from Natto Extract - Non-GMO, Gluten Free - 50 Servings
#TOP2
Solgar Vitamin K2 (Mk-7) 100Mcg, 50 Vegetable Capsules
9.8
PM SCORE
Solgar Vitamin B12 1000 mcg, 250 Nuggets - Supports Production of Energy, Red Blood Cells - Healthy Nervous System - Promotes Cardiovascular Health - Vitamin B - Non-GMO, Gluten Free - 250 Servings
#TOP3
Solgar Vitamin B12 1000 Mcg, 250 Nuggets -
9.8
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Vegetarian Enzyme Supplements of 2026

Solgar Yeast-Free Selenium 200 Mcg, 100 Tablets - Supports Antioxidant & Immune System Health - Non-Gmo, Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings

SOLGAR
30233
1.97 X 1.97 X 3.44 Inches
0.35 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Yeast-Free Selenium; Selenium is an essential trace mineral; This formulation provides yeast-­free selenium as L-­selenomethionine

Antioxidant Health; Selenium is a component of the antioxidant enzyme glutathione peroxidase, which helps to fight cell-­damaging free-­radicals; Selenium also helps recycle Vitamin E, which adds additional antioxidant support

Gluten, Wheat & Dairy Free; Solgar Yeast-Free Selenium is non-GMO, vegan, kosher, and free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color

The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials

During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

Solgar Vitamin K2 (Mk-7) 100Mcg, 50 Vegetable Capsules - Supports Bone Health - Natural Whole Food Source From Natto Extract - Non-Gmo, Gluten Free - 50 Servings

SOLGAR
30268
1.97 X 1.97 X 3.44 Inches
0.25 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Supports Bone Health; Vitamin K2 is an active form of Vitamin K and is important for bone health

Active Form; Vitamin K2 is not readily found in the diet and is manufactured by gut microflora; Vitamin K2 can also be extracted from a natural whole food source, the fermented soybean product Natto, a natural source of MK-7

Natto Extract; This form of natural vitamin K2 is sourced from Natto extract

Non-GMO, Gluten & Wheat Free; Solgar Vitamin K2 is free of: gluten, wheat, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color; Suitable for lacto-vegetarians

The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials

During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

Solgar Vitamin B12 1000 Mcg, 250 Nuggets - Supports Production Of Energy, Red Blood Cells - Healthy Nervous System - Promotes Cardiovascular Health - Vitamin B - Non-Gmo, Gluten Free - 250 Servings

SOLGAR
30249
1.97 X 1.97 X 3.44 Inches
0.19 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Along with Folic Acid and Vitamin B6, it supports heart health by promoting healthy levels of homocysteine

Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery

Required for the normal development and regeneration of red blood cells, which help to deliver oxygen throughout the body

Convenient nugget dosage form

Solgar Yeast-Free Selenium 200 Mcg, 250 Tablets - Supports Antioxidant & Immune System Health - Non-Gmo, Vegan, Gluten Free, Dairy Free, Kosher - 250 Servings, Unflavored, Standard Packaging

SOLGAR
30234
2.42 X 2.42 X 4.31 Inches
0.75 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Yeast-Free Selenium; Selenium is an essential trace mineral; This formulation provides yeast-­free selenium as L-­selenomethionine

Antioxidant Health; Selenium is a component of the antioxidant enzyme glutathione peroxidase, which helps to fight cell-­damaging free-­radicals; Selenium also helps recycle Vitamin E, which adds additional antioxidant support

Gluten, Wheat & Dairy Free; Solgar Yeast-Free Selenium is non-GMO, vegan, kosher, and free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color

The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials

During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

Solgar Dry Vitamin E With Yeast-Free Selenium, Advanced Antioxidant Support - Immune & Skin Support - Non-Gmo, Vegan, Gluten Free, Dairy Free, Kosher - 100 Count (Pack Of 1)

SOLGAR
E3351
2.42 X 2.42 X 4.31 Inches
0.44 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
vitamin plus 9.68

Features

Advanced Antioxidant Support; As a component of the antioxidant enzyme, glutathione peroxidase, selenium helps to fight cell-damaging free radicals in the body; It spares vitamin E, which in turn supports the cell’s antioxidant defense system

Immune System & Skin Support; Vitamin E and Selenium provide nutritional support for the immune system and healthy skin

Oil-Free Form; This formulation provides natural vitamin E in a dry (non-oily) form, for those who have difficulty digesting fats and oils; It is offered in a convenient, two-piece, vegetarian capsule

Gluten, Wheat & Dairy Free; Solgar Dry Vitamin E is non-GMO, vegan, kosher, and free of: gluten, wheat, dairy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color

The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials

Solgar Yeast-Free Selenium 100 Mcg, 100 Tablets - Supports Antioxidant & Immune System Health - Non-Gmo, Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings

SOLGAR
E2551
1.78 X 1.78 X 3.25 Inches
0.25 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
recommerce 9.99

Features

Yeast-Free Selenium; Selenium is an essential trace mineral; This formulation provides yeast-­free selenium as L-­selenomethionine

Antioxidant Health; Selenium is a component of the antioxidant enzyme glutathione peroxidase, which helps to fight cell-­damaging free-­radicals; Selenium also helps recycle Vitamin E, which adds additional antioxidant support

Gluten, Wheat & Dairy Free; Solgar Yeast-Free Selenium is non-GMO, vegan, kosher, and free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color

The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials

During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

Solgar Dlpa 500 Mg, 100 Vegetable Capsules - Free Form Dl-Phenylalanine - Supports Central Nervous System - Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings (Pack Of 2)

SOLGAR
30149
1.00 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Free Form DL-Phenylalanine; DL-phenylalanine is a mixture of both the D and L forms of the amino acid phenylalanine

Nervous System Support; DLPA may have the unique ability to reduce the activity of the enzyme enkephalinase in the central nervous system, thereby sparing feel good hormones such as endorphins and enkephalins

Optimal Absorption; This formulation provides free form DLPA to promote optimal absorption and assimilation

Gluten, Wheat & Dairy Free; Solgar DLPA is vegan, kosher, and free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color; Suitable for vegetarians

The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials

During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

#TOP8

Solgar Dlpa 500 Mg, 100 Vegetable Capsules - Free Form Dl-Phenylalanine - Supports Central Nervous System - Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings

SOLGAR
30149
2.57 X 2.57 X 4.67 Inches
0.50 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Free Form DL-Phenylalanine; DL-phenylalanine is a mixture of both the D and L forms of the amino acid phenylalanine

Nervous System Support; DLPA may have the unique ability to reduce the activity of the enzyme enkephalinase in the central nervous system, thereby sparing feel good hormones such as endorphins and enkephalins

Optimal Absorption; This formulation provides free form DLPA to promote optimal absorption and assimilation

Gluten, Wheat & Dairy Free; Solgar DLPA is vegan, kosher, and free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color; Suitable for vegetarians

The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials

Solgar Lactase 3500 Chewable Wafers, 30 Count

SOLGAR
E810
1.78 X 1.78 X 3.25 Inches
0.19 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
DealonUS 9.38

Features

Chewable wafers

Salt and starch free

Suitable for vegetarians

Solgar Dry Vitamin E With Yeast-Free Selenium Vegetable Capsules, 50 Count

SOLGAR
E3350
1.97 X 1.97 X 3.44 inches
0.25 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

Dry (non-oily) form, for those who have difficulty digesting fats and oils

Synergistic, antioxidant formulation is offered in a convenient, two-piece, vegetarian capsule

As a component of the antioxidant enzyme, glutathione peroxidase, selenium helps to fight cell-damaging free radicals in the body

Solgar Chelated Zinc, 250 Tablets - Zinc For Healthy Skin + Solgar Yeast-Free Selenium 200 Mcg, 250 Tablets - Supports Antioxidant & Immune System Health

SOLGAR
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Optimal Absorption; Solgar Chelated Zinc contains a patented, chelated form of zinc to help promote optimal absorption; The 22 mg of zinc in this formulation represent 200% of the recommended daily value

Immune Support; Zinc exerts antioxidant activity and can support a healthy immune system; It also supports cell growth and DNA formation

Yeast-Free Selenium; Selenium is an essential trace mineral; This formulation provides yeast-­free selenium as L-­selenomethionine

Antioxidant Health; Selenium is a component of the antioxidant enzyme glutathione peroxidase, which helps to fight cell-­damaging free-­radicals; Selenium also helps recycle Vitamin E, which adds additional antioxidant support

Top 10 enzyme supplements Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Solgar 11

Top 10 enzyme supplements Brands Pie Chart


We've carried out a comprehensive analysis of 12,211 reviews on enzyme supplements, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select enzyme supplements priced around $23.17, with top brands including biomedic labs rx, nature's choice supplements, bulksupplements.com, enzyme science, home brew ohio, bluebonnet, now, wonderland herbs and garden of life and doctor's best

Our team of expert editors reviewed these high-quality items and handpicked the top 11 enzyme supplements for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include biomedic labs rx, nature's choice supplements!, bulksupplements, enzyme science ™, bluebonnet nutrition, nature and herbs, akersunder, amazon.com and holistic 4 all and lovewellness .

We are dedicated to assisting our users in finding the right supplements Products based on their needs, saving them considerable time when choosing which enzyme supplements to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.