Best Generic Face Serums in 2026

Daisy
Last Updated: Jul 19, 2026

At a Glance: Our Top Picks for Generic Face Serums

Obagi Professional C Serum 20%, Vitamin C Facial Serum with Concentrated 20% L Ascorbic Acid for Normal to Oily Skin, 1.0 Fl Oz Pack of 1 Product Name
#TOP1
Obagi Professional C Serum 20%, Vitamin C Facial
9.8
PM SCORE
Obagi Medical Nu-Derm Exfoderm Forte, 2 oz Pack of 1
#TOP2
Obagi Medical Nu-Derm Exfoderm Forte, 2 Oz Pack
9.7
PM SCORE
obagi Vitamin C Serum 15% - Professional C Serum Skin Care – Contains Concentrated L Ascorbic Acid - Helps Minimize the Appearance of Wrinkles, Brightens Skin, and Retains Moisture- 1.0 Fl Oz.
#TOP3
Obagi Vitamin C Serum 15% - Professional C
9.6
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Generic Face Serums of 2026

Obagi Professional C Serum 20%, Vitamin C Facial Serum With Concentrated 20% L Ascorbic Acid For Normal To Oily Skin, 1.0 Fl Oz Pack Of 1 Product Name

OBAGI MEDICAL
5053/OM
2.09 X 1.53 X 4.00 Inches
0.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Nutritional Vitamin 9.92

Features

Visibly Youthful Skin - You'll love the way your skin looks after using this facial skin care product 20% Vitamin C Serum! It helps minimize the appearance of fine lines and wrinkles and is especially great for normal to oily skin. Plus, this face care product will brighten the area around your eyes to help your skin look younger as well.

Brighten Up Your Skin!- Experience the true brightness of your skin with this Vitamin C for Face Product. This hydrating serum’s fast-acting formula will immediately penetrate the skin to enhance brightness & with regular use you’ll be glowing with joy at how great this facial serum antiaging product made your skin look. Great for normal to oily skin

Long-Lasting Hydration -Looking for a face skin care product that can provide lasting hydration? Look no further! Our Vitamin C Skin Care Serum is a brightening serum that provides superior moisture retention, leaving your skin hydrated and refreshed for longer. Unlock the power of long-lasting hydration today!

Skin Soothing Serum - Calm and soothe your skin with Obagi’s Vitamin-C Face Serum for Dark Spots. This skin repair serum’s calming and moisturizing effects will help you look and feel relaxed and refreshed and its special combination of L-Ascorbic Acid & other medically formulated ingredients will help minimize the appearance of unwanted fine lines & wrinkles as well.

Protect Your Skin - Our clinically formulated Vitamin C antiaging serum has been designed to help retain moisture & protect your skin from environmental stressors. This face serum for women also provides nourishment and refreshes the skin so that you can have peace of mind knowing your skin is well protected from the elements

Obagi Medical Nu-Derm Exfoderm Forte, 2 Oz Pack Of 1

OBAGI MEDICAL
7013/OM
1.27 X 1.98 X 4.00 Inches
0.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Nutritional Vitamin 9.92

Features

Exfoliate & Brighten Your Skin: Obagi Nu Derm Exfoderm Forte is a lightweight face lotion for men & women that helps exfoliate the top layer of the skin, removing dull, old skin cells, while revealing new skin cells for a brighter complexion. This face cream is suitable for oily & normal skin, making this product a must have exfoliator for almost any skincare regimen.

Made With Powerful Ingredients - Obagi Nu Derm Exfoderm Forte is formulated with powerful ingredients, such as glycolic acid, lactic acid, emu oil and saponins, 2 in , exfoliator and face moisturizer to nourish and hydrate skin for a softer, smoother complexion.

Reduce Signs of Anti-aging: For a brighter more youthful appearance, use Obagi’s Complete Nu Derm FX System. The Nu Derm system includes Obagi’s Nu Derm Exfoderm Forte, but it also has 6 other skincare products that when applied together as a routine can help you reduce the signs of anti-aging & enhance your complexion overall.

Medical Skincare Brand: Obagi Medical is a global medical skincare brand that's focused on creating skincare products that help unleash the full potential of the skin. Our skincare products are formulated to deal with a wide range of skin care issues including acne, aging, hyperpigmentation and much more.

How to Apply: For the best results, use this exfoliate for face daily in the morning, squeeze a small amount (approximately one to two pea size drops) onto your hands, use your fingertips to apply the exfoliator evenly on your entire face and massage until completely absorbed into your skin.

Obagi Vitamin C Serum 15% - Professional C Serum Skin Care – Contains Concentrated L Ascorbic Acid - Helps Minimize The Appearance Of Wrinkles, Brightens Skin, And Retains Moisture- 1.0 Fl Oz.

OBAGI MEDICAL
5052/OM
2.09 X 1.53 X 4.00 Inches
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Nutritional Vitamin 9.92

Features

Visibly Youthful Skin - You'll love the way your skin looks after using this 15% Vitamin C Serum! It helps minimize the appearance of fine lines and wrinkles and is especially great for normal to oily skin. Plus, it brightens the area around your eyes to help your skin look younger as well.

Brighten Up Your Skin!- Experience the true brightness of your skin with this hydrating serum . With its fast-acting formula, it will immediately penetrate the skin to enhance brightness & with regular use you’ll be glowing with joy at how great your skin looks. Great for normal to oily skin.

Long-Lasting Hydration -Looking for a face skin care product that can provide lasting hydration? Look no further! Our Vitamin C Skin Care Serum is a brightening serum provides superior moisture retention, leaving your skin hydrated and refreshed for longer. Unlock the power of long-lasting hydration today!

Skin Soothing Serum - Calm and soothe your skin with Obagi’s Vitamin-C Face Serum. This skin repair serum’s calming and moisturizing effects will help you look and feel relaxed and refreshed and its special combination of L-Ascorbic Acid & other medically formulated ingredients will help minimize the appearance of unwanted fine lines & wrinkles as well.

Protect Your Skin - Our clinically formulated Vitamin C facial serum antiaging product has been designed to help retain moisture & protect your skin from environmental stressors. This face serum for women also provides nourishment and refreshes the skin so that you can have peace of mind knowing your skin is well protected from the elements

Obagi Daily Hydro-Drops Hydrating Facial Serum For Dry Skin, 1 Fl Oz - Moisturizing Serum For Face - Hypoallergenic Face Serum With Moisture-Preserving Formula For More Radiant, Healthy-Looking Skin

OBAGI MEDICAL
I0108336
1.40 X 1.40 X 4.80 Inches
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Nutritional Vitamin 9.92

Features

Hydrate & Smoothen Your Skin- Obagi Medical’s Daily Hydro Drops Serum for face is an innovative hydrating face skincare made with cutting edge technology to leave your skin smoother, more radiant, & hydrated throughout the day.

This hydrating serum for face is Made with Cutting Edge Isoplentix technology- Isoplentix microfluidic technology provides the purest form of Vitamin B3, Abyssinian Oil, and Hibiscus Oil, along with an instant infusion of hydration, to help soften the appearance of fine lines and wrinkles.

Dermatologist-Approved Serum- This serum for skincare has been tested & approved by dermatologists and ophthalmologists. Not only is it clinically safe, but it’s hypoallergenic and non-comedogenic, meaning it will not clog pores or cause irritation.

Auto-filling Dropper: Using this face care serum is easy! Just untwist cap to loosen & the serum dropper will fill automatically so you never have to worry about filling the dropper. Once the dropper is filled with the serum, just apply a few drops onto your fingertips & apply evenly to the face, neck, & decollete to fully infuse the suspended drops onto your skin. Apply morning & evening after cleansing for best results.

Skin Benefits: Using a facial skin care products like this serum in your skincare routine can help keep your skin hydrated

Obagi Elastiderm Facial Serum, Face Serum With Bi-Mineral Contour Complex For All Skin Types - Anti Aging Serum For Face, Neck, And Decollete - 1.0 Oz

OBAGI MEDICAL
I0108335
1.93 X 1.93 X 4.49 Inches
0.30 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Nutritional Vitamin 9.92

Features

Youthful Healthy-Looking Skin: As we age, our skin loses its elasticity, which can result in fine lines, wrinkles, and sagging skin. That’s why Obagi’s Elastiderm Serum for face is designed to help support the elasticity of skin so your skin can bounce back from the signs of aging. Leaving with you more resilient & youthful, firmer- looking skin with this face care hydrating serum.

Promotes Elastin Development: Obagi’s Facial Serum is made with a patented Bi-Mineral Contour Complex that harnesses Zinc, Copper, & Malonate to promote the three necessary stages of developing healthy elastin.

Improve Your Skin’s Texture: Using these facial skin care products like Obagi’s facial serums can help improve your skin’s texture by supporting collagen production. Collagen is a special protein that helps keep the skin firm and smooth, and using a serum that supports this production can lead to smoother, more even-looking skin.

How to Apply: Just apply 2-3 pumps of this face serum for women at morning & night on a clean dry face. For the best results, use this serum for anti aging along with the Elastiderm Eye Cream & Eye Serum. Serum works best for dry, normal & oil skin.

Hydrate & Nourish Your Skin: Obagi Medical’s Facial Serum contains a combination of hydrating and nourishing ingredients that allow the serum to help reduce saggy skin, harsh fine lines & wrinkles, skin aging, & much more.

Obagi Vitamin C Serum 10% - Professional C Serum Skin Care – Contains Concentrated L Ascorbic Acid - Helps Minimize The Appearance Of Wrinkles, Brightens Skin, And Retains Moisture- 1.0 Fl Oz.

OBAGI MEDICAL
2724450748982
2.09 X 1.54 X 4.00 Inches
0.07 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Nutritional Vitamin 9.92

Features

Visibly Youthful Skin - You'll love the way your skin looks after using this 10% Vitamin C Serum! It helps minimize the appearance of fine lines and wrinkles and is especially great for normal to oily skin. Plus, it brightens the area around your eyes to help your skin look younger as well.

Brighten Up Your Skin!- Experience the true brightness of your skin with this serum - with its fast-acting formula, it will immediately penetrate the skin to enhance brightness & with regular use you’ll be glowing with joy at how great your skin looks. Great for Normal to Oily skin

Long-Lasting Hydration -Looking for lasting hydration? Look no further! Our Vitamin C brightening serum provides superior moisture retention, leaving your skin hydrated and refreshed for longer. Unlock the power of long-lasting hydration today!

Skin Soothing Serum - Calm and soothe your skin with Obagi’s Vitamin-C Face Serum. Its calming and moisturizing effects will help you look and feel relaxed and refreshed and its special combination of L-Ascorbic Acid & other medically formulated ingredients will help minimize the appearance of unwanted fine lines & wrinkles

rotect Your Skin - Our clinically formulated Vitamin C facial serum antiaging product has been designed to help retain moisture & protect your skin from environmental stressors. This face serum for women also provides nourishment and refreshes the skin so that you can have peace of mind knowing your skin is well protected from the elements.

Obagi Medical Facial Moisturizer And Professional C Serum 20% Vitamin C Facial Serum

OBAGI MEDICAL
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Nutritional Vitamin 9.92

Features

NON-COMEDOGENIC 8-HOUR MOISTURIZER - provides instant and long-lasting hydration day or night. Clinically shown to improve the moisture content of the skin and provide hydration for up to eight hours. Designed for a variety of skin types to help enhance skin smoothness.

VITAMIN C 20% - Highest concentrated serum with antioxidant L-ascorbic Acid, best suited for normal to oily skin. Uniquely formulated to help reduce the appearance of skin aging and leave skin feeling silky soft.Daily use helps to fortify skin and safeguard your youthful appearance. Formulated with pure L-ascorbic acid to optimize efficacy, permeability, and stability. Obagi Professional-C Serum 20% is the highest concentrated serum with antioxidant L-ascorbic Acid, best suited for normal to oil

HOW TO USE - Apply 5 to 7 drops of Obagi Professional-C Serum to the face, neck and chest using fingertips. Apply to cleansed skin in the morning before sunscreen or makeup application. Apply Obagi Hydrate to face in the morning and evening or as needed.

KEY INGREDIENTS - Hydromanil (Hydrate) and L-ascorbic Acid (Vitamin C Drops)

SKIN TYPE - All skin types

Obagi Medical 360 Retinol 1.0 And Professional C Serum 20% Vitamin C Bundle

OBAGI MEDICAL
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Nutritional Vitamin 9.92

Features

OBAGI 360 RETINOL 1.0 TECHNOLOGY- Retinol 1.0 gradually refines skin texture while effectively minimizing the appearance of fine lines and wrinkles. Obagi’s Retinol features retinol entrapment technology which makes it effective with minimal irritation.

VITAMIN C 20% - Highest concentrated serum with antioxidant L-ascorbic Acid, best suited for normal to oily skin. Uniquely formulated to help reduce the appearance of skin aging and leave skin feeling silky soft.Daily use helps to fortify skin and safeguard your youthful appearance. Formulated with pure L-ascorbic acid to optimize efficacy, permeability, and stability. Obagi Professional-C Serum 20% is the highest concentrated serum with antioxidant L-ascorbic Acid, best suited for normal to oil

HOW TO USE - Apply 5 to 7 drops of Obagi Professional-C Serum to the face, neck and chest using fingertips. Apply to cleansed skin in the morning before sunscreen or makeup application. Use the Retinol 1.0 once daily in the evening.

KEY INGREDIENTS - Retinol (Retinol 1.0) and L-ascorbic Acid (Vitamin C Drops)

SKIN TYPE - All skin types

Obagi Medical Retivance Skin Rejuvenating Complex And Professional C Vitamin C Facial Serum

OBAGI MEDICAL
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Nutritional Vitamin 9.92

Features

SKIN REJUVENATING COMPLEX - Formula combines clinically studied ingredients such as retinaldehyde and antioxidant Vitamin C and Vitamin E to improve skin texture and reduce the appearance of fine lines and wrinkles.

VITAMIN C 20% - Highest concentrated serum with antioxidant L-ascorbic Acid, best suited for normal to oily skin. Uniquely formulated to help reduce the appearance of skin aging and leave skin feeling silky soft.Daily use helps to fortify skin and safeguard your youthful appearance. Formulated with pure L-ascorbic acid to optimize efficacy, permeability, and stability. Obagi Professional-C Serum 20% is the highest concentrated serum with antioxidant L-ascorbic Acid, best suited for normal to oil

HOW TO USE - Apply 3 pumps of the Retivance Skin Rejuvenating Complex to the face and massage gently into the skin. Feather onto the jawline and neck. Apply 5 to 7 drops of Obagi Professional-C Serum to the face, neck and chest using fingertips. Apply to cleansed skin in the morning before sunscreen or makeup application.

KEY INGREDIENTS - Retinal (Retivance) and L-ascorbic Acid (Vitamin C Drops).

SKIN TYPE - All skin types.

#TOP10
Best For Oily

Obagi Professional C Serum 20%, Vitamin C Facial Serum With Concentrated 20% L Ascorbic Acid For Normal To Oily Skin, 1.0 Fl Oz Pack Of 2

OBAGI MEDICAL
0.13 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Nutritional Vitamin 9.92

Features

Visibly Youthful Skin - You'll love the way your skin looks after using this facial skin care product 20% Vitamin C Serum! It helps minimize the appearance of fine lines and wrinkles and is especially great for normal to oily skin. Plus, this face care product will brighten the area around your eyes to help your skin look younger as well.

Top 10 face serums Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Obagi Medical 10

Top 10 face serums Brands Pie Chart


We've carried out a comprehensive analysis of 3,471 reviews on face serums, using our selection criteria to identify the best options in the categories. Our findings reveal that most customers typically select face serums priced around $154.91, with top brands including and

Our team of expert editors reviewed these high-quality items and handpicked the top 10 face serums for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the categories category. These include and .

We are dedicated to assisting our users in finding the right serums Products based on their needs, saving them considerable time when choosing which face serums to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.