Daisy
Last Updated: Jul 19, 2026
* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
#1 Clinically Recommended Menthol Topical Pain Relief Brand (*IPSOS Clinician Survey, July 2022)
Biofreeze Menthol Pain Relieving Gel, spray and roll-on apply easily and penetrate for pain relief
Fast acting, cooling menthol formula delivers penetrating pain relief for minor aches and pains of muscles and joints associated with simple backache, arthritis, strains, bruises, and sprains
Biofreeze is a clinically recommended brand; trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers
Product is not tested on animals, made with USP grade menthol, and free Of NSAIDs
Biofreeze is FSA/HSA eligible. Save up to 30%
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Soymedical | 9.87 | ✅ | ✅ | ✅ |
One 2.75 oz can of Dermoplast Pain, Burn & Itch Spray
Provides immediate pain and itch relief for minor skin irritations and postpartum care
Maximum OTC strength of benzocaine provides immediate pain relief, menthol soothes and refreshes, and aloe and lanolin moisturize
No-touch application lets you spray on relief without additional pain
Clean affected area and apply Dermoplast spray
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
#1 Clinically Recommended Menthol Topical Pain Relief Brand (*IPSOS Clinician Survey, July 2022)
Biofreeze Professional Pain Relieving Spray applies easily to hard-to-reach areas such as the middle back, neck, and lower extremities
Fast acting, cooling menthol formula delivers penetrating pain relief for minor aches and pains of muscles and joints associated with simple backache, arthritis, strains, bruises, and sprains
The 4 fl oz 360° spray bottle features the best spray technology available with continuous flow even when upside down
Biofreeze is a clinically recommended brand; trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers
Product is not tested on animals, made with USP grade menthol, and free of NSAIDs
Biofreeze is FSA/HSA eligible. Save up to 30%
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
#1 Clinically Recommended Menthol Topical Pain Relief Brand (*IPSOS Clinician Survey, July 2022)
Biofreeze Pain Relieving Spray applies easily to hard-to-reach areas such as the middle back, neck, and lower extremities
Fast acting, cooling menthol formula delivers penetrating pain relief for minor aches and pains of muscles and joints associated with simple backache, arthritis, strains, bruises, and sprains
The 4 fl oz 360° spray bottle features the best spray technology available with continuous flow even when upside down
Biofreeze is a clinically recommended brand; trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers
Product is not tested on animals, made with USP grade menthol, and free of NSAIDs
Biofreeze is FSA/HSA eligible. Save up to 30%
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
The 3 fl oz 360° spray bottle features the best spray technology available with continuous flow even when upside down
Biofreeze is a clinically recommended brand; trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers
Product is not tested on animals, made with USP grade menthol, and free of NSAIDs
Biofreeze is FSA/HSA eligible. Save up to 30%
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Explosive Bargains | 9.71 | ❌ | ❌ | ❌ |
#1 Clinically Recommended Menthol Topical Pain Relief Brand (*IPSOS Clinician Survey, July 2022)
Biofreeze Pain Relieving Spray applies easily to hard-to-reach areas such as the middle back, neck, and lower extremities
Fast acting, cooling menthol formula delivers penetrating pain relief for minor aches and pains of muscles and joints associated with simple backache, arthritis, strains, bruises, and sprains
The 4 fl oz 360° spray bottle features the best spray technology available with continuous flow even when upside down
Biofreeze is a clinically recommended brand; trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers
Biofreeze is FSA/HSA eligible. Save up to 30%
Product is not tested on animals, made with USP grade menthol, and free of NSAIDs
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Quality You Can Trust | 9.90 | ✅ | ✅ | ✅ |
100% Colorless
Dye Free
Paraben Free
Gluten Free
Contains Natural Ingredients MSM, Arnica, Boswellia, Eucalyptus, ILEX, Menthol, Peppermint Oil
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ❌ |
ALEVE X PAIN RELIEVING SPRAY, contains the active ingredients Menthol and Camphor that penetrates to relieve minor aches and pains associated with arthritis
DRIES 4X FASTER: Compared to other leading topical pain relief brands, Aleve X is preferred due to its ingredients of Camphor and 16% Menthol
ALEVE X PAIN RELIEVING LOTION WITH ROLLERBALL APPLICATOR, contains the active ingredients Menthol and Camphor that penetrates to relieve minor aches and pains associated with arthritis
2X MORE PREFERRED: Compared to other leading topical pain relief brands, Aleve X is preferred due to its ingredients of Camphor and 16% Menthol
WORKS FAST AND LASTS LONG: The spray remains on the targeted spot and provides a cooling sensation that won't wear off quickly
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Quality You Can Trust | 9.90 | ✅ | ✅ | ✅ |
Includes: (1) CryoDerm 32oz Spray Cold Therapy
Ingredients: Purified Water, SD Alcohol 39-C, Arnica, Boswellia, Eucalyptus Oil, ILEX, Menthol, Peppermint Oil, and Dimethyl Sulfone
CRYODERM is 100% colorless, dye free, paraben free and gluten free. For external use only.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Avadim Health, Inc | 9.88 | ✅ | ✅ | ✅ |
Fast relief for leg, foot and other muscle cramps
Prevents new muscle cramps and spasms when used daily
Reduces the soreness after a cramp or spasm
Non-toxic, locally acting, total-body-safe ingredients
Made in the USA
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Contains one (1) 4-oz. bottle of Icy Hot Dry Spray, Maximum Strength
PAIN RELIEF: Icy Hot menthol pain-relief spray helps temporarily relieve minor pains associated with back pain, arthritis pain, muscle pain, sprains, bruises and muscle cramps
FAST-ACTING: This pain-relieving spray provides maximum-strength pain relief at the push of a button
NO-MESS SPRAY: Continuous spray is formulated to dry instantly and works at any angle for fast, convenient pain relief
AMERICA'S TOPICAL PAIN RELIEF BRAND*: *Among OTC topical analgesics.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Royal Meds | 9.95 | ❌ | ❌ | ❌ |
ICY HOT MEDICATED CREAM: This Icy Hot cream delivers fast acting pain relief for minor joint & muscle pain associated with arthritis, simple backache, muscle strains, sprains, bruises & cramps. Non-greasy pain relieving cream starts working on contact.
TOPICAL PAIN RELIEF: Our creams & patches deliver icy coolness to dull the pain & relaxing heat to help relieve achy muscles. With Icy Hot, you'll get fast, long lasting relief that helps reduce pain from muscle aches, arthritis, joint pain, & cramps.
ICY HOT PAIN RELIEF: Icy Hot carries a variety of pain relieving solutions, from creams, lotions, balms, and gels to sprays, patches, & SmartRelief TENS Therapy products. From back pain to knee injuries to arthritis, our products can help ease your pain.
A WELL ROUNDED MEDICINE CABINET: When you or a family member is in pain, sick, hurt, or just generally feeling under the weather, you don’t want to run to the pharmacy. A well stocked home medicine cabinet helps ensure relief is at hand when you need it.
PAIN RELIEF: Icy Hot offers chronic pain relief for back, joints, shoulders, knees & sore muscles. Try our prescription strength medicated creams, lotions, sprays, gels & balms for pain management.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
INCLUDES: One (1) 4-oz. bottle of Icy Hot Max Strength Pain Relief Dry Spray With Lidocaine Plus Menthol
NUMBS AWAY PAIN: Icy Hot Lidocaine Spray desensitizes aggravated nerves to temporarily relieve minor pains associated with back pain, knee pain and muscle pain
FAST ACTING & LONG LASTING: This pain-relieving spray penetrates to the nerves for pain relief at the push of a button
NO-MESS SPRAY: Continuous spray dries quickly and works at any angle for fast, easy pain relief
AMERICA'S TOPICAL PAIN RELIEVER: Icy Hot is the number-one topical pain relief brand among OTC topical analgesics
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| ❌ | ❌ | ❌ |
Extra Strength Pain Relief: This aches and pains relief cream allows you to massage into muscles to help relieve tightness and discomfort; Perfect for general full body muscle aches and after workouts
Vegan Ointment: This extra strength ointment cream features 95 percent natural botanicals and essential oils like Boswellia and peppermint oil, as well as 10 percent menthol to help with pain relief
Accessible and Approachable Products: We infuse our formula with high quality and natural ingredients featuring vitamin E, omega 3 and 6 fatty acids to create pain relief creams, capsules, oils and sprays for optimal wellness and balance
All Day Relief: Our products help support you throughout the day; Each topical pain relief product includes botanicals and essential oils that are cultivated to the highest standards
Whole Self Wellness : We want to harness the benefits of full spectrum natural botanicals to help you do more of what you love; Since 2015, we’ve worked with chemists and naturopaths to create products with dedication to whole self wellness
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Active Recovery Essentials | 9.92 | ✅ | ✅ | ✅ |
ANALGESIC SPRAY. Tiger Balm Active Muscle Spray is a high-quality analgesic spray that is formulated to support your active lifestyle
FOR HARD-TO-REACH AREAS. Whether you have a backache, strains, or sprains, Tiger Balm Active Muscle Spray may help provide cooling, temporary relief for hard-to-reach areas
NON-GREASY. This muscle spray is easy to apply, non-greasy, and does not stain. It may be used as a pre-sport warm-up and after exercise, or it may help soothe sore muscles and joints
SOOTHING FORMULA. Tiger Balm Active Muscle Spray is formulated with topical analgesics including methyl salicylate 25%, menthol 16%, and camphor 7%. For adults and children over 12 years of age, spray on the affected area. Repeat 3–4 times daily
WARNINGS. This product is for external use only. It should only be used as directed. Avoid contact with eyes and mucous membranes. Do not apply to wounds or damaged, irritated skin
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Ameretail | 9.85 | ❌ | ❌ | ❌ |
Crafted with Natural Magnesium and Camphor to provide temporary pain relief.
Easy Application: Spray J.R. Watkins Magnesium Muscle Pain Relief Spray onto painful area and let absorb into skin. Apply no more than four times per day.
From J.R. Watkins: Since 1868, we have been delivering potent, plant-based home and body remedies that not only soothe, but solve.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Topical cooling spray
Instantly cools skin
Reduces swelling and pain
4 O spray can
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Includes one (1) 4-ounce canister of Icy Hot PRO Dry Spray
Fast-acting, powerful relief for aching muscles and joints
This quick-drying formula contains menthol and camphor, two maximum-strength pain relievers
The Icy Hot PRO Dry Spray actuator sprays at any angle to reach hard-to-reach places
Icy Hot is America's #1 topical pain relief brand**
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
SOOTHES MUSCLES + RELIEVES SWELLING: Brings instant cooling comfort + Vitamin E + Squalene
EASY APPLICATOR: 360-spray lets you go the distance to reach your calves and feet, even if you can’t touch your toes.
PREGNANCY SKIN SAFE: Safe and gentle for all trimesters, but specially recommended for the 2nd + 3rd tri when swelling is super common
NO PHTHALATES + PARABENS: And no fragrances, dyes or alcohol.
DERMATOLOGIST-TESTED: So you know it’s legit for your skin
NOT TESTED ON ANIMALS: Cruelty-free
NET WEIGHT: 3.4 ounces
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Tattoo Depot | 9.68 | ✅ | ✅ | ✅ |
NUMB IT UP: Whether you’re about to go under the tattoo gun, wax some body/facial hair, or get a piercing, this 5% lidocaine numb spray can make the process a whole lot less painful. Rushing relief in just 5-15 minutes which lasts up to an hour, this topical anesthetic can spare you from a painful ordeal.
DITCH THE ITCH: You can also use this spray to relieve common skin conditions that cause pain, itching or discomfort such as minor burns, insect bites, eczema, scratches and even hemorrhoids.
QUICK RELIEF: At Inked Inspired, we know that when you really need relief, you don’t want to wait half an hour for it to take effect. That’s why we created our formula to start working in as little as five minutes. Within 15 minutes, this tattoo numbing spray will have reached peak effectiveness at both numbing and soothing pain or itchiness.
MAXIMUM STRENGTH: With 5% lidocaine, we made our numb spray as strong as we could without requiring a prescription. The result is blissful though temporary relief from conditions that would otherwise cause discomfort on the surface of your skin.
SOOTHING SATISFACTION: If you’re not happy with the effectiveness of Inked Inspired numbing spray, just let us know and we’ll make it right. There’s no need to suffer from the pain resulting from that piercing, waxing, tattoo, or other skin condition; click Buy Now and say aaaaah with the quick numbing action of maximum strength spray from Inked Inspired!
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Medenviro International, LLC | 7.69 | ✅ | ✅ | ✅ |
NATURAL JOINT PAIN CREAM FROM PURE ESSENTIAL OILS - Flexigen is crafted with a unique blend of premium, therapeutic-grade natural essential oils including Frankincense which is known for its ability to ease pain from inflammation. Flexigen also contains skin-nourishing ingredients like aloe, calendula, and orange peel oil to offer instant, long-lasting comfort from pain, sprains, strains, injuries, and swelling, and it’s safe for everyday use for chronic pain management.
QUICK, LONG-LASTING JOINT, MUSCLE & LIGAMENT CREAM - This deep-penetrating formula is fast-acting and works for hours, targeting areas of pain and soreness in your back, neck, shoulders, knees, hands, and more. The ingredients work together in perfect harmony to keep discomfort from holding you back from your favorite activities. It soothes skin and has an herbal scent that vanishes quickly. Finally, say goodbye to backaches, joint pain, pain from swelling, bruising, and muscle soreness.
NO HARMFUL CHEMICALS, NSAIDS, BURNING, OR SKIN IRRITATION - Flexigen uses natural ingredients to target joint and muscle discomfort at the source. It’s dermatologist-tested, made in the USA, hypoallergenic, and gentle even on the most sensitive skin. Thanks to plant-based menthol and naturally-derived moisturizers, Flexigen provides immediate comfort and soothing hydration without irritating or burning skin. It’s free from harmful chemicals and NSAIDs, and it’s an over-the-counter medication.
NON-GREASY, ULTRA-MOISTURIZING & PERFECTLY PACKAGED - Flexigen absorbs quickly and completely into your skin, and unlike most pain-easing creams, it’s non-sticky, non-greasy, and doesn’t stain. It holds 180 pumps in every unique, leak-proof airless spray bottle that’s easy to use and offers full control so there’s no spillage or excess. Plus, Flexigen is travel-friendly so you can take it anywhere. Use this topical as a standalone treatment or with heating pads, ice packs, or muscle massagers.
EXTRA STRENGTH WITHOUT THE EXTRA RISK & OVERPOWERING SCENT - It works! Ease your joints and muscles, and feel good from the inside out—without the nose-burning scent that comes from most pain gels, topicals, and sprays! Apart from being infused with 100% pure essential oils and skin-hydrating ingredients, Flexigen is a great solution for pain. If you’re not happy with this pharmacist formula, make sure to take advantage of our pain-free refund policy. Flexigen is also FSA/HSA Eligible.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Quality You Can Trust | 9.90 | ✅ | ✅ | ✅ |
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| TIDLSPORT | 9.49 | ✅ | ✅ | ❌ |
Go Beyond Relief: Our Plant Powered Performance Spray & Cream fitness products not only deliver fast-acting, long-lasting relief from muscle and joint pain using only natural, plant-based ingredients, they promote quicker recovery so you can get back out there
Spray for Full Body Treatment: Ideal for supplementing an intense training regimen, Cryotherapy Spray provides effective pain relief, healing, and joint relief for the whole body
Use the Cream For Deep Absorption: This cream is specifically formulated for deep tissue absorption in order to provide instant relief and encourage fast recovery from demanding training protocols
Easy Application: The spray goes on cool but is never sticky, with 360 Degree Spray Technology to ensure optimal coverage; the mentholated cream goes on cool and immediately delivers a soothing sensation
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| TOMORROW'S DISTRIBUTION | 9.93 | ❌ | ❌ | ❌ |
#1 Clinically Recommended Menthol Topical Pain Relief Brand (*IPSOS Clinician Survey, July 2022)
Biofreeze Pain Relieving Spray applies easily to hard-to-reach areas such as the middle back, neck, and lower extremities
Fast acting, cooling menthol formula delivers penetrating pain relief for minor aches and pains of muscles and joints associated with simple backache, arthritis, strains, bruises, and sprains
The 4 fl oz 360° spray bottle features the best spray technology available with continuous flow even when upside down
Biofreeze is a clinically recommended brand; trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers
Product is not tested on animals, made with USP grade menthol, and free of NSAIDs
Biofreeze is FSA/HSA eligible. Save up to 30%
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| NFI Consumer Products - BLUE-EMU | 9.90 | ✅ | ✅ | ❌ |
Maximum Pain Relief Cream: Our cream starts with deep penetrating emu oil and includes 10% Trolamine Salicylate for temporary relief of muscle and joint pain.
Our creams and sprays are always odor-free, non-greasy, and fast absorbing. No menthol odor and no burning, stinging, or irritation.
Continuous Pain Relief Spray: Our spray makes our tried and true pain relief formula into a 360° spray for hard to reach areas.
Our spray dries quickly and absorbs fast so you get the relief you need exactly where you hurt.
Made in the USA in a cGMP certified facility
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Mma Blast Kickboxing | 7.38 | ❌ | ❌ | ❌ |
#1 Clinically Recommended Menthol Topical Pain Relief Brand (*IPSOS Clinician Survey, July 2022)
Biofreeze Menthol Pain Relieving Gel, spray and roll-on apply easily and penetrate for pain relief
Fast acting, cooling menthol formula delivers penetrating pain relief for minor aches and pains of muscles and joints associated with simple backache, arthritis, strains, bruises, and sprains
TSA approved sizing makes it convinient for travel and on-the-go pain relief
Biofreeze is a clinically recommended brand; trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers
Biofreeze is FSA/HSA eligible. Save up to 30%
Product is not tested on animals, made with USP grade menthol, and free of NSAIDs
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Nyloxin Chronic Pain Relief | 5.80 | ✅ | ✅ | ❌ |
WORKS BEST WHEN USED REGULARLY OVER TIME: Use least 4 times per day in the first week. As pain becomes more tolerable, reduce use to an as-needed basis. Nyloxin works best when used regularly over time.
Here is the list of top-rated brands that were evaluated by PM.
| Brand | Count |
|---|---|
| Biofreeze | 7 |
| Icy Hot | 4 |
| Cryoderm | 3 |
| Aleve | 1 |
| Blue Emu | 1 |
| Flexigen | 1 |
| Frida Baby | 1 |
| Inked Inspired | 1 |
| J.r. Watkins | 1 |
| Medique | 1 |
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