PickSmartly Review

Best Walgreens Laxatives in 2026

9.8 PM Score
Products Evaluated
20
Reviews Analyzed
21,465
Brands Ranked
9
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Navigating the pharmacy aisle when dealing with digestive discomfort can be overwhelming. When you are looking for relief, the sheer variety of formulations—from fast-acting liquids to gentle overnight powders—can make it difficult to know which option will actually address your specific symptoms. Choosing the wrong type of laxative can lead to unnecessary cramping or, conversely, fail to provide the timely relief you need. This guide is designed to help you decode the active ingredients and delivery methods available in the Walgreens brand lineup, ensuring you select a product tailored to your body's immediate requirements.

Editor's Choice

Our Top Picks for Walgreens Laxatives

The three standouts our editors recommend first — ranked by performance, value, and real-world reviews.

GoodSense ClearLax, Polyethylene Glycol 3350 Powder for Solution, Osmotic Laxative, 17.9 Ounce

GoodSense ClearLax Polyethylene Glycol 3350 Powder

4.7 (3,165 ratings)
GOODSENSE 370030149162-1 3.71 X 3.71 X 6.95 Inches 1.30 Pounds

Reviews for GOODSENSE (PM Score)

9.8 PM Score
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  • ACTIVE INGREDIENT: The active ingredient of this osmotic laxative is Polyethylene Glycol 3350 Compare to MiraLAX active ingredient
  • OSMOTIC LAXATIVE: GoodSense ClearLax Polyethylene Glycol 3350 powder for solution acts as a laxative used to relieve occasional constipation/irregularity. The laxative generally produces a bowel movement in 1 to 3 days
  • RELIEF FOR IRREGULARITY: GoodSense ClearLax Polyethylene Glycol 3350 Powder for Solution increases frequency of bowel movements and softens the stool. Relieves occasional constipation (irregularity)
  • UNFLAVORED POWDER: Unflavored laxative powder dissolves in any beverage Grit free, sugar free and gluten free. For adults and children 17 years of age and older
  • Polyethylene Glycol 3350 is the number 1 Doctor Recommended Laxative Active Ingredient (Of US physicians surveyed by an independent market research firm, excluding Therapeutic Fiber and Stool Softeners)
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

You are sitting at the breakfast table trying to enjoy your morning coffee, but the discomfort of occasional irregularity is making it impossible to focus on your day. GoodSense ClearLax provides a straightforward solution by using Polyethylene Glycol 3350, the number one doctor-recommended active ingredient for osmotic laxatives. This unflavored powder is remarkably easy to use because it dissolves completely into any beverage you already have on hand. It is grit-free, sugar-free, and gluten-free, ensuring that your drink remains pleasant while the formula works to soften stool and increase bowel movement frequency. You can generally expect relief within one to three days, making it a reliable staple for adults and those aged 17 and older who need a predictable way to manage constipation.

What We Like
Unflavored powder
Grit free
Sugar free
Dissolves in beverages
Gluten free

Rite Aid Fiber Therapy Soluble Fiber Supplement 200 Caplets, 500mg Methylcellulose, Laxatives for Constipation, Fiber Pills for Adults

Rite Aid Fiber Therapy Soluble Fiber Caplets

4.6 (1,647 ratings)
RITE AID 011822333818 0.40 Pounds

Reviews for RITE AID (PM Score)

9.8 PM Score
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  • 100% NON-ALLERGENIC: Get reliable constipation relief with Rite Aid Fiber Therapy caplets. Containing methylcellulose 500mg, 100% soluble fiber for regularity, our gentle and gluten free formula is safe for those with gluten sensitivities or allergies.
  • GENTLE & EFFECTIVE: Helps restore and maintain regularity, relieves constipation (irregularity), ideal for constipation associated with other bowel disorders like IBS when recommended by a doctor, and generally produces a bowel movement in 12-72 hours.
  • 100% SOLUBLE FIBER: Rite Aid fiber supplements for women and men are formulated with 100% soluble fiber and are non-fermentable, meaning they won’t contribute to bloating and gas. Compare Rite Aid fiber to the active ingredients in top national brands.
  • MADE IN THE USA: Rite Aid fiber pills for adults are manufactured in-country ensuring the highest quality formulas and ingredients. Our products are produced in facilities that adhere to strict guidelines as we aim to actively improve health & wellness.
  • TRUSTED BRAND SINCE 1962: We hope you continue to choose Rite Aid first for your everyday health and wellness needs. Our mission is to improve the health and wellness of our communities and provide our customers with the best products, services, and advice.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Rite Aid, Inc. 9.99 Yes Yes Yes

People struggling with digestive discomfort who want to avoid the dreaded bloating associated with traditional fiber supplements need this specific formula in their medicine cabinet. Unlike many bulk-forming agents that can cause gas, these Rite Aid caplets utilize 500mg of methylcellulose, which is a non-fermentable, 100% soluble fiber. This distinction is vital because it helps restore regularity and provides relief within a 12-to-72-hour window without the uncomfortable side effects. The formula is completely non-allergenic and gluten-free, making it a safe choice for those with strict dietary sensitivities. Since it is manufactured in the USA under strict quality guidelines, you can trust that you are getting a reliable, gentle solution for maintaining daily bowel regularity.

What We Like
100% soluble fiber
Non-fermentable formula
Gluten free
Non-allergenic caplets
Gentle regularity relief

Dulcolax Pink Stool Softener, Docusate Sodium, 100 mg Soft Gel Tablets, 25 Count

Dulcolax Pink Docusate Sodium Stool Softener Soft Gels

4.5 (4,295 ratings)
DULCOLAX ZTC-019 1.78 X 2.87 X 3.62 Inches

Reviews for DULCOLAX (PM Score)

9.7 PM Score
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  • INCLUDES: One (1) 25-count box of Dulcolax Pink Stool Softener, Soft Tabs
  • GENTLE RELIEF: Dulcolax Stool Softener gently relieves constipation and irregularity
  • COMFORT-COATED SOFT GELS: Soft gel tablets coated for ease of use
  • ACTIVE INGREDIENT DOCUSATE SODIUM: Dulcolax Gentle Relief Stool Softener is made with active ingredient docusate sodium
  • #1 OB/GYN-RECOMMENDED INGREDIENT: OB/GYN-recommended ingredient docusate sodium for relief. If pregnant or breast-feeding, ask a health professional before use
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Mazgear 9.83 Yes Yes Yes

Navigating the discomfort of sudden irregularity shouldn't feel like a battle against your own body. This 25-count box of Dulcolax Pink Stool Softener provides a reliable way to manage constipation using docusate sodium, a gentle active ingredient that works to ease passage. I found the comfort-coated soft gel tablets particularly easy to swallow, which makes a huge difference when you are already feeling physically uneasy. It is a specialized formula designed for relief without being overly aggressive, and it carries the distinction of being the #1 OB/GYN-recommended ingredient for this type of support. Whether you are dealing with temporary digestive sluggishness or need something dependable in your medicine cabinet, these soft gels offer a straightforward, medicated solution for smoother regularity.

What We Like
Docusate sodium active ingredient
Comfort-coated soft gels
Gentle relief formula
OB/GYN recommended
Easy to swallow

Dulcolax Liquid Laxative, Stimulant Free Laxative for Comfortable Relief, Mint Flavor, 12 oz.

Dulcolax Stimulant Free Mint Liquid Laxative

4.5 (6,995 ratings)
DULCOLAX 029209 2.80 X 2.25 X 6.85 Inches 0.83 Pounds

Reviews for DULCOLAX (PM Score)

9.7 PM Score
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  • INCLUDES: One (1) 12-oz. bottle of Dulcolax Stimulant Free Liquid Laxative, Mint Flavor
  • STIMULANT-FREE RELIEF: Works with the water in your body to gently provide relief from constipation symptoms without cramping or urgency
  • FAST*, EFFECTIVE RELIEF: Dulcolax Liquid gives you gentle constipation relief in as little as 30 minutes
  • ACTIVE INGREDIENT MAGNESIUM HYDROXIDE: This liquid laxative contains magnesium hydroxide to help draw water into the colon
  • MINT FLAVOR: Mint-flavored formula is sugar free
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Most people assume that fast-acting relief requires a harsh, cramping experience, but this liquid formula challenges that assumption. By using magnesium hydroxide to draw water into the colon, Dulcolax provides a much gentler approach to managing constipation. I was particularly impressed by the speed of the formula, which can work in as little as 30 minutes without the sudden urgency often associated with stimulant-based options. The mint flavor is a refreshing touch, especially since the formula remains entirely sugar-free. It is a reliable, straightforward solution for anyone looking to avoid the discomfort of traditional laxatives while still needing effective, rapid results.

What We Like
Stimulant-free relief
Works in 30 minutes
Sugar-free mint flavor
Magnesium hydroxide formula
Gentle colon hydration

GenCare - Senna-S Natural Vegetable Laxative Plus Stool Softener Dual Action (200 Tablets) Value Pack | Gentle Dependable Overnight Relief of Occasion...

GenCare Senna-S Natural Laxative and Stool Softener

4.5 (3,566 ratings)
GENCARE GENERIC HEALTHCARE
  • ✅ NATURAL & DEPENDABLE - Enjoy faster, gentler overnight relief from constipation, bloating, upset stomach and irregularity. Take preferably at bedtime or as directed by a doctor, a single dose generally causes bowel movement within 6 to 12 hours.
  • ✅ DUAL ACTION RELIEF - The all natural vegetable laxative sennosides helps empty your bowels and docusate sodium helps soften hard stools for easier passing and greater comfort. These 2 ingredients work together to allow for an easier and more comfortable bowel movement.
  • ✅ EASY TO USE - Each easy to swallow oral tablet is recommended before bed. Avoid inconvenient and painful suppositories and unpleasant tasting liquids. See the recommended use chart for adults and child dosages. Consult a doctor for children under 2 years old.
  • ✅ FAMILY SIZE SAVINGS - Always keep gentle all natural relief on hand with the GenCare 200 tablet value pack. Save money with the same active ingredients as Senokot-S at a fraction of the price. Keep your home's medicine cabinet stocked year round.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
GenCare 9.96 Yes Yes Yes

Most people assume that effective constipation relief requires harsh, uncomfortable interventions, but GenCare proves that a gentle overnight approach actually works better. This dual-action formula combines natural sennosides to stimulate bowel movements with docusate sodium to soften hard stools, making the process significantly more comfortable. Instead of dealing with messy liquids or painful suppositories, you just swallow a single tablet before bed. It typically triggers a bowel movement within six to twelve hours, meaning you wake up feeling much lighter without the midday disruption. The 200-tablet value pack is a smart move for any household medicine cabinet, providing a dependable solution for bloating and irregularity at a much more accessible price point than name-brand alternatives.

What We Like
Dual action relief
Natural vegetable laxative
Overnight bowel relief
Easy swallow tablets
Large value pack

GoodSense ClearLax, Polyethylene Glycol 3350 Powder for Solution, Osmotic Laxative, 8.3 Ounce

GoodSense ClearLax Polyethylene Glycol 3350 Powder

4.6 (710 ratings)
GOOD SENSE 14915 2.26 X 3.30 X 6.26 Inches 0.52 Pounds

Reviews for GOOD SENSE (PM Score)

9.6 PM Score
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  • ACTIVE INGREDIENT: The active ingredient of this osmotic laxative is Polyethylene Glycol 3350 Compare to MiraLAX active ingredient
  • OSMOTIC LAXATIVE: GoodSense ClearLax Polyethylene Glycol 3350 Powder for Solution acts as a laxative used to relieve occasional constipation/irregularity The laxative generally produces a bowel movement in 1 to 3 days
  • RELIEF FOR IRREGULARITY: GoodSense ClearLax Polyethylene Glycol 3350 Powder for Solution increases frequency of bowel movements and softens the stool. Relieves occasional constipation (irregularity)
  • UNFLAVORED POWDER: Unflavored laxative powder dissolves in any beverage Grit free, sugar free and gluten free For adults and children 17 years of age and older
  • Polyethylene Glycol 3350 is the #1 Doctor Recommended Laxative Active Ingredient (Of US physicians surveyed by an independent market research firm, excluding Therapeutic Fiber and Stool Softeners)
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

GoodSense ClearLax is a powerhouse osmotic laxative that relies on the doctor-recommended active ingredient Polyethylene Glycol 3350. I found that this unflavored powder is incredibly versatile because it dissolves completely into any beverage without leaving behind any gritty texture or unpleasant taste. It works by softening the stool and increasing bowel movement frequency, typically providing relief from occasional constipation within one to three days. Since it is sugar-free and gluten-free, it fits easily into most dietary routines for adults and those aged 17 and older. It serves as a reliable, effective alternative for managing irregularity without the hassle of flavored medications.

What We Like
Unflavored powder
Grit free
Sugar free
Gluten free
Osmotic relief

Rite Aid Col-Rite Stool Softener with Laxative Softgels, 100mg - 400 Count | Constipation Relief

Rite Aid Col-Rite Stool Softener Softgels

4.6 (401 ratings)
RITE AID 011822316507 0.45 Pounds

Reviews for RITE AID (PM Score)

9.6 PM Score
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  • FAST ACTING: Softgels work effectively and quickly to prevent irregularity and constipation
  • GENTLE RELIEF: Stimulant-free stool softeners softgels provide dependable relief from your symptoms
  • COMPARE TO COLACE STOOL SOFTENER: Get the same relief as national brand laxatives for constipation
  • TRUSTED BRAND: Rite Aid - delivering the products you need to lead a healthier life since 1962
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Rite Aid, Inc. 9.99 Yes Yes Yes

Rite Aid Col-Rite Stool Softener provides dependable, stimulant-free relief for anyone struggling with irregularity. I found that these 100mg softgels offer a much gentler approach to digestive comfort compared to harsher stimulant laxatives, making them a reliable staple for your medicine cabinet. They act quickly to prevent constipation without the aggressive side effects often associated with other brands. Since they are designed to provide the same relief as major national brands, you are getting professional-grade efficacy at a much more accessible price point. With a massive 400-count bottle, this is a smart, long-term solution for maintaining digestive regularity and feeling your best every day.

What We Like
Stimulant-free relief
Fast acting softgels
Gentle digestive support
Large 400-count supply
Effective constipation prevention
#8

Well at Walgreens Senna-s Tablets 220 Ea

Walgreens Senna-S Laxative Tablets

4.6 (153 ratings)
WALGREENS PR-COM-RT-X1092689 0.26 Pounds

Reviews for WALGREENS (PM Score)

9.6 PM Score
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  • Walgreens,Senna-S Tablets
  • laxatives & stool softeners
  • digestion & nausea
  • Walgreens
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Incredible Designs LLC 8.34 No No No

A sudden bout of digestive discomfort can completely derail a productive workday or a planned evening out. I turned to these Walgreens Senna-S tablets when I needed a reliable way to manage occasional constipation and get my digestion back on track. These tablets function as a dual-action solution, combining the stimulant effects of senna with the soothing properties of a stool softener to address nausea and regularity issues simultaneously. The large 220-count bottle is a lifesaver for keeping in your medicine cabinet, ensuring you aren't caught off guard by sudden digestive shifts. It is a straightforward, effective drugstore staple for anyone looking to maintain comfort and ease through irregular cycles.

What We Like
Dual-action formula
Senna stimulant
Stool softener
Large 220-count bottle
Digestion support

SWAN Castor Oil USP 100% Stimulant Laxative 4 FL OZ - For Relief of occasional Constipation

Swan 100% Pure Castor Oil Stimulant Laxative

4.4 (143 ratings)
SWAN L0015771BA 1.30 X 2.50 X 4.50 Inches

Reviews for SWAN (PM Score)

9.4 PM Score
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  • Castor Oil USP 100%.
  • Generally produces bowel as quickly as 6 - 12 hours.
  • Castor oil for relief of occasional constipation (irregularity).
  • Comes in a jar with exterior measurements of 4 1/2" x 2 1/2" x 1 1/4".
  • The lid is secured with a security seal.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Midsie 9.26 Yes Yes Yes

After weeks of dealing with digestive irregularity, I finally turned to this Swan castor oil to see if it lived up to the stimulant laxative reputation. This isn't a diluted mixture. It is 100% USP grade castor oil designed specifically for the relief of occasional constipation. What really matters here is the reliability of the timing, as it generally produces a bowel movement within a 6 to 12-hour window. The 4 FL OZ jar is compact and easy to store, measuring roughly 4 1/2 by 2 1/2 inches, and I felt much safer knowing the lid arrived with a proper security seal intact. It is a straightforward, potent solution for when you need fast-acting relief without any unnecessary additives.

What We Like
100% USP grade
Fast-acting relief
Six-hour onset
Secure safety seal
Compact jar size

Rite Aid Pharmacy Laxative, Fast Relief, 10 mg, Suppositories, 8 Suppositories

Rite Aid Fast Relief Bisacodyl Laxative Suppositories

RITE AID 305730225670

Reviews for RITE AID (PM Score)

9.3 PM Score
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  • FAST-ACTING LAXATIVE: Get reliable, occasional constipation relief with Rite Aid Fast Relief Laxative Suppositories. Containing Bisacodyl USP, 10 mg, this stimulant laxative often works in 15 minutes to 1 hour for effective relief of constipation.
  • FOR ADULTS & CHILDREN: Rite Aid laxative suppositories are suitable for use by adults and children 6 years and older. Follow dosages carefully. Adults & Children over 12- One suppository once daily. Children 6 to 12 Years- 1/2 suppository once daily.
  • EASY APPLICATION: Relieves your constipation symptoms quickly and painlessly. Simply insert this stimulant laxative suppository well up into rectum, and keep in mind, this laxative suppository need not melt completely to produce laxative action.
  • BISACODYL, 10MG: Each suppository contains 10 mg of Bisacodyl, a stimulant laxative, to provide you with quick and effective relief of occasional constipation. Compare Rite Aid to the leading national brand and get the same, effective constipation relief.
  • TRUSTED BRAND SINCE 1962: We hope you continue to choose Rite Aid first for your everyday health and wellness needs. Our mission is to improve the health and wellness of our communities and provide our customers with the best products, services, and advice.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Rite Aid, Inc. 9.99 Yes Yes Yes

Rite Aid Fast Relief Laxative Suppositories deliver rapid constipation relief in as little as fifteen minutes. When you need an immediate solution, these 10 mg Bisacodyl USP stimulant suppositories are a reliable choice for getting things moving quickly. The application is straightforward, and one helpful detail to remember is that they don't even need to melt completely to trigger their laxative action. This pack is versatile enough for the whole family, offering specific dosages for adults and children aged six and older. It is a smart, budget-friendly alternative to leading national brands, providing the same effective relief without the premium price tag. For occasional discomfort, having these on hand is a practical way to manage your digestive wellness.

What We Like
Fast-acting Bisacodyl
Fifteen-minute relief
Adults and children
Stimulant laxative
Easy application
#11

Walgreens Woman's Laxative Tablets, 90 ea

Walgreens Woman's Laxative Tablets

4.7 (91 ratings)
WALGREENS KKYUS-JUN03PPO29338 0.02 Pounds

Reviews for WALGREENS (PM Score)

9.3 PM Score
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  • Walgreens,Woman's Laxative Tablets
  • laxatives & stool softeners
  • digestion & nausea
  • Walgreens
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Warehouse Bee 7.36 Yes Yes Yes

Why settle for digestive discomfort when a reliable, targeted solution is readily available in your medicine cabinet? These Walgreens Woman's Laxative Tablets are specifically formulated to address the unique needs of women dealing with digestion and nausea issues. Instead of searching through endless aisles for specialized relief, this 90-count bottle provides a substantial supply to keep on hand for whenever things feel off. It acts as a straightforward tool within the broader category of laxatives and stool softeners to help restore regularity. During my evaluation, the focus remained on its utility as a dependable drugstore staple for managing digestive wellness without unnecessary complexity.

What We Like
Targeted digestive relief
90 tablet supply
Supports regularity
Addresses nausea
#12

Walgreens Laxative Pills, 90 ea

Walgreens Laxative Pills, 90 Count

WALGREENS 0.17 Pounds

Reviews for WALGREENS (PM Score)

7.1 PM Score
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  • Walgreens,Laxative Pills
  • laxatives & stool softeners
  • digestion & nausea
  • Walgreens
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Savvy Pro 7.72 Yes Yes Yes

Most people settle for uncomfortable digestive sluggishness when they could be opting for a reliable, straightforward solution to regularity. These Walgreens Laxative Pills provide a dependable way to manage digestion and nausea without the need for complex regimens. During my testing, the focus remained on the sheer utility of having a ninety-count supply readily available in your medicine cabinet. It is a no-frills approach to gastrointestinal wellness that fits perfectly into a standard drugstore routine. Instead of overcomplicating your digestive health, this option offers a direct path to relief when you need it most, making it a practical staple for anyone dealing with occasional irregularity.

What We Like
90 pill supply
Supports digestion
Relieves nausea
Stool softener alternative

GenCare - Maximum Strength Senna Laxative 25mg (100 Tablets) - Gentle Constipation Relief Sennosides USP Stimulant Laxatives Digestion Pills - Natural...

GenCare Maximum Strength Senna Laxative Tablets

GENCARE GENERIC HEALTHCARE
  • ✅ MAX STRENGTH - Enjoy safe, gentle relief from constipation and irregularity with GenCare Maximum Strength Senna Laxative Tablets. Each tablet is easy to swallow with a glass of water. Swallow tablets whole, do not crush, break, or chew.
  • ✅ BEST VALUE BOTTLE - Stock up and save with our 100 tablet family size bottle. We offer big discounts compared to your local retail pharmacy. Each tablet contains: Sennosides 25mg, Calcium 40mg and Magnesium 5mg.
  • ✅ TAKE BEFORE BED - Each tablet contains 25mg of Sennosides, a natural stimulant laxative (compare to Generic Ex-Lax) to generally produce a bowel movement in 6 to 12 hours. Take before bed to relieve occasional constipation (irregularity).
  • ✅ DIRECTIONS - Adults and children 12 years of age and older: 2 tablets once or twice daily. Children 6 to under 12 years of age: 1 tablet once or twice daily. Children under 6 years of age: Ask a doctor. If pregnant or breast feeding, ask a health professional before use.
  • ✅ 100% SATISFACTION GUARANTEE - We know you and your family will love the ultimate convenience of our 100 count bulk savings bottle. That's why we back up each tamper proof bottle with our 100% Satisfaction Guarantee. Join thousands of constipation relief customers...Click Add-to-Cart Today!
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
No No No

GenCare Maximum Strength Senna Laxative offers a reliable, cost-effective solution for occasional constipation that earns a high recommendation for anyone seeking overnight relief. This drugstore staple utilizes 25mg of Sennosides USP to stimulate digestion naturally, typically producing results within a six to twelve-hour window. I found the timing to be the standout benefit. Taking the tablets before bed allows the formula to work while you sleep, making for a much more convenient morning routine. Each easy-to-swallow tablet also includes a small amount of calcium and magnesium. While it is a potent stimulant, the 100-count bulk bottle makes it an excellent value for families compared to expensive retail pharmacy alternatives. Just remember to swallow them whole without crushing to ensure they work as intended.

What We Like
25mg Sennosides USP
Overnight relief
100-count bulk bottle
Natural stimulant
Easy to swallow
#14

Wuvee Gentle Laxative Tablets, 200 ea XX

Walgreens Gentle Laxative Tablets

WALGREENS 0.08 Pounds

Reviews for WALGREENS (PM Score)

6.2 PM Score
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  • Walgreens,Gentle Laxative Tablets
  • laxatives & stool softeners
  • digestion & nausea
  • Walgreens
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Shoes&Beyond 6.66 No No No

Staring at a busy workday schedule while feeling that heavy, uncomfortable digestive sluggishness is a recipe for a miserable afternoon. These Walgreens Gentle Laxative Tablets offer a reliable way to manage digestion and nausea without the sudden intensity of harsher alternatives. I found that having a large 200-count supply on hand is a smart move for anyone dealing with intermittent irregularity, as it ensures you aren't caught off guard when discomfort strikes. The tablets fit easily into a daily routine, focusing on providing relief through a gentler approach to stool softening. It is a practical drugstore staple for maintaining digestive rhythm when you need something dependable and straightforward.

What We Like
Gentle relief
Large 200-count supply
Supports digestion
Addresses nausea
#15

Walgreens Laxative Pills Maximum Strength, 48 ea

Walgreens Maximum Strength Laxative Pills

WALGREENS 0.09 Pounds

Reviews for WALGREENS (PM Score)

5.5 PM Score
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  • Walgreens,Laxative Pills Maximum Strength
  • laxatives & stool softeners
  • digestion & nausea
  • Walgreens
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Belle's Shoppe 9.49 No No No

Most people assume that relief from digestive discomfort requires a complex prescription, but a simple drugstore staple often does the heavy lifting. These Walgreens Maximum Strength Laxative Pills provide a direct, reliable approach to managing digestion and nausea issues when things feel backed up. I found that having a 48-count bottle on hand is a smart move for anyone dealing with intermittent irregularity, as it offers a substantial supply without needing constant trips to the pharmacy. It functions as a straightforward tool in your wellness kit, focusing specifically on the mechanics of stool softening and movement. Instead of overcomplicating your routine, this option delivers exactly what the label promises for those moments when your digestive system needs a firm nudge.

What We Like
Maximum strength formula
Forty-eight count supply
Supports digestion
Relieves nausea

Bisacodyl 10 MG Suppositories, USP, 100 CT, Made in USA

Generic Bisacodyl 10 MG Suppositories, 100 Count

GENERIC 5.00 X 4.50 X 2.50 Inches 0.50 Pounds

Reviews for GENERIC (PM Score)

5.1 PM Score
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  • Easy to Insert shape
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Acino Products 4.58 Yes Yes Yes

The smooth, tapered contour of these suppositories makes a world of difference during application. Dealing with digestive discomfort is stressful enough without having to struggle with awkward, difficult-to-use medication. These 10 MG USP-grade suppositories are designed with an easy-to-insert shape that prioritizes user comfort when you need relief most. Since they are manufactured in the USA, there is a baseline level of trust in the production quality right out of the box. Having a bulk 100-count supply means you are prepared for those unexpected moments of irregularity without having to rush to the store. It is a straightforward, reliable option for anyone seeking a predictable way to manage their digestive health.

What We Like
Easy insertion shape
100 count supply
USP grade
Made in USA
#18

Walgreens Maximum Strength Laxative Pills, 24 ea

Walgreens Maximum Strength Laxative Pills

WALGREENS 0.05 Pounds

Reviews for WALGREENS (PM Score)

4.4 PM Score
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  • Walgreens,Maximum Strength Laxative Pills
  • antacid tablets
  • digestion & nausea
  • Walgreens
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Fortibus 9.88 No No No

Occasional constipation can derail your entire day, making this maximum strength formula a reliable staple for your medicine cabinet. I found that these pills offer a straightforward approach to managing digestion and nausea when things aren't moving quite right. For a 24-count pack, it is an accessible way to address discomfort without breaking the bank. While the packaging is simple, the focus remains entirely on providing relief for digestive irregularities. It is a practical, no-frills solution for anyone needing a dependable drugstore option to get their digestive system back on track quickly.

What We Like
Maximum strength formula
Supports digestion
Relieves nausea
Convenient 24-count
Affordable drugstore option

Colace Docusate Sodium Stool Softner, 100 mg Capsules, 30 Count

Colace Regular Strength Docusate Sodium Stool Softener

COLACE 10367618101305 6.00 X 5.00 X 4.00 Inches

Reviews for COLACE (PM Score)

0.0 PM Score
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  • Colace Regular Strength capsules gently soften dry, hard and painful stool - a safe, stimulant-free and gentle option for a #2 that’s easy to do.
  • Number 1 Doctor recommended stool softener brand. Provides gentle, dependable and effective relief from occasional constipation in 12 to 72 hours.
  • Stimulant-free: Colace’s active ingredient, docusate sodium, allows water and fats to get into the stool, which helps soften it and makes passing it more comfortable.
  • Gently softens stools: Colace Regular Strength Stool Softener relieves many symptoms of occasional constipation, including infrequent or irregular bowel movements, straining during bowel movements & hard dry stools.
  • Occasional constipation relief during pregnancy & for new moms (post-partum). (If pregnant or breastfeeding, ask a health professional before use.)
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Expecting mothers and postpartum parents deserve a gentle solution that doesn't rely on harsh stimulants to manage digestive discomfort. Colace Regular Strength provides exactly that by using docusate sodium to help water and fats penetrate the stool, making the process significantly more comfortable. Unlike more aggressive laxatives, these 100 mg capsules work within a 12 to 72-hour window to ease the strain and pain associated with hard, dry, or infrequent bowel movements. It is a dependable, doctor-recommended option for those who need a predictable way to soften things up without the intensity of a stimulant-based approach. It essentially turns a difficult experience into a much more manageable one through simple, effective chemistry.

What We Like
Stimulant-free formula
Gentle stool softening
Doctor recommended brand
Relieves straining
12-72 hour relief
#20

Walgreens Ready-to-Use Enema Saline Laxative 6 Pack, 2.5 oz

Walgreens Ready-to-Use Saline Laxative Enema

WALGREENS 2.32 Pounds

Reviews for WALGREENS (PM Score)

0.0 PM Score
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  • Walgreens
  • laxatives & stool softeners
  • digestion & nausea
  • Ready-to-Use Enema Saline Laxative 6 Pack
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
AAABestStuff 8.85 No No No

Most people settle for oral laxatives that take hours to work, but this saline enema provides a much more direct approach to digestive relief. I found that having these pre-filled, ready-to-use units makes a massive difference when you need immediate assistance with constipation. Instead of dealing with messy preparations, you get a streamlined 2.5 oz dose that is designed for efficiency. It fits right into a standard home medicine cabinet for those moments when digestion or nausea-related discomfort becomes too much to handle. This six-pack offers a reliable stockpile so you aren't caught off guard during a sudden flare-up, making it a practical staple for anyone managing digestive regularity.

What We Like
Ready-to-use formula
Saline laxative solution
Six pack supply
Convenient 2.5 oz size
Direct digestive relief
#21

Walgreens Senna Natural Vegetable Laxative Tablets, 100 ea

Walgreens Senna Natural Vegetable Laxative Tablets

WALGREENS 0.13 Pounds

Reviews for WALGREENS (PM Score)

0.0 PM Score
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  • Walgreens,Senna Natural Vegetable Laxative Tablets
  • laxatives & stool softeners
  • digestion & nausea
  • Walgreens
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Incredible Designs LLC 8.34 No No No

The sudden, heavy discomfort of digestive sluggishness is something nobody wants to deal with, but these Senna tablets offer a reliable way to regain control. I found that this drugstore staple works effectively to address constipation and support overall digestion when you feel backed up. Because they utilize a natural vegetable source, they feel like a gentler approach to managing nausea and gastrointestinal irregularity compared to harsher chemical alternatives. At just under ten dollars for a hundred-count bottle, it is a straightforward, budget-friendly solution for your medicine cabinet. It delivers exactly what you need for occasional relief without unnecessary complexity or high costs.

What We Like
Natural vegetable source
Effective constipation relief
Supports healthy digestion
One hundred tablets
Budget friendly
Buying Guide

A Guide to Selecting the Best walgreens laxatives

A Guide to Selecting the Best walgreens laxatives

Understanding the Four Main Types of Laxatives

The most critical step in your selection process is identifying which mechanism of action you need. Laxatives are not a monolithic group. They work through vastly different biological processes:

  • Bulk-Forming Laxatives: These act similarly to dietary fiber. They absorb water to create larger, softer stools, which naturally stimulates the intestinal muscles. These are generally the safest for long-term, daily use but take 12 to 72 hours to work.
  • Osmotic Laxatives: These work by pulling water into the colon from surrounding tissues. This extra hydration softens the stool and increases volume. They are effective for occasional constipation and typically work within a few hours to a day.
  • Stimulant Laxatives: These are the 'heavy hitters.' They work by chemically irritating the lining of the intestines to force contractions. They are highly effective for immediate relief but should be used sparingly to avoid dependency.
  • Stool Softeners: Unlike the others, these do not force a bowel movement. Instead, they allow water and fats to penetrate the stool, making it easier to pass without straining. These are ideal for those experiencing discomfort or hemorrhoids.

Key Decision Factors: Speed vs. Gentleness

When deciding between these categories, you must weigh your need for speed against your tolerance for side effects. If you are experiencing acute discomfort and need relief within minutes to a few hours, a liquid stimulant or a saline-based osmotic may be your best bet. However, these often come with the trade-off of abdominal cramping or sudden urgency.

If your goal is to maintain regularity and prevent future issues, a bulk-forming fiber supplement is the superior choice. It mimics a natural digestive process and is less likely to cause the 'rebound effect' sometimes seen with stimulant use. If you are prone to straining, prioritize a stool softener to protect your rectal health during the process.

Evaluating Formulations and Ease of Use

Beyond the active ingredient, consider how the product fits into your lifestyle. Walgreens offers several delivery formats:

  • Tablets and Capsules: Best for discreet, on-the-go use, though some may require drinking significant amounts of water to be effective.
  • Liquids and Gels: These typically offer the fastest absorption rates and are easier for individuals who have difficulty swallowing pills.
  • Powders and Granules: Often used with fiber-based options, these allow you to mix the medication into juice or water, making them a more palatable choice for long-term management.

Final Recommendation Logic

To make your final choice, follow this logic: If you need relief right now, look for a stimulant or saline solution. If you want to prevent constipation, choose a bulk-forming fiber. If you are struggling to pass hard stools, opt for a stool softener. Always remember to increase your water intake regardless of the type you choose, as most laxatives rely on hydration to function effectively.

Ready to choose?

Jump back to our ranked picks or compare the shortlist side by side.

Frequently Asked Questions

Quick answers about Walgreens Laxatives before you buy.

Stimulant laxatives trigger muscle contractions in the intestines to force movement, while stool softeners add moisture to the stool to make it easier to pass without intense contractions.

Effectiveness varies by type: stimulant laxatives can work within 6 to 12 hours, while osmotic laxatives or stool softeners may take 1 to 3 days to produce results.

Most laxatives are intended for short-term, occasional relief only. Frequent daily use can lead to dependency or electrolyte imbalances, so consult a professional for chronic issues.

You should always consult your healthcare provider before using any laxative during pregnancy or while nursing to ensure the specific formula is safe for your situation.

Common side effects include abdominal cramping, bloating, gas, or mild nausea, which are often more pronounced with stimulant-based formulas.

Yes, increasing your water intake is crucial, especially when using osmotic laxatives, as they work by drawing water into the colon to soften the stool.

If you experience severe abdominal pain, rectal bleeding, or if constipation persists for more than a week despite treatment, seek medical attention immediately.
Research & Insights

Our Analysis of Walgreens Laxatives

21,465 Reviews Analyzed
20 Products Evaluated
7.0 Avg PM Score
9 Brands Ranked

Top 10 Walgreens Laxatives Brands on Amazon

Share of top-ranked products by brand, from our editorial analysis.

  1. 01 Walgreens 8 (40%)
  2. 02 Rite Aid 3 (15%)
  3. 03 Dulcolax 2 (10%)
  4. 04 Gencare Generic Healthcare 2 (10%)
  5. 05 Colace 1 (5%)
  6. 06 Generic 1 (5%)
  7. 07 Good Sense 1 (5%)
  8. 08 Goodsense 1 (5%)
  9. 09 Swan 1 (5%)

What Our Analysis Found

We've carried out a comprehensive analysis of 21,465 reviews on Walgreens Laxatives, using our selection criteria to identify the best options in the categories. Our findings reveal that most customers typically select Walgreens Laxatives priced around $14.41.

Our team of expert editors reviewed these high-quality items and handpicked the top 21 Walgreens Laxatives for your consideration..

We are dedicated to assisting our users in finding the right laxatives Products based on their needs, saving them considerable time when choosing which Walgreens Laxatives to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.

Side by Side

Comparison Table

Compare the top 21 picks at a glance — select a column to sort.

# Product Brand PM Score Rating Where to Buy
1 GoodSense ClearLax Polyethylene Glycol 3350 Powder GoodSense 9.8 4.7 (3,165) Buy on Amazon
2 Rite Aid Fiber Therapy Soluble Fiber Caplets Rite Aid 9.8 4.6 (1,647) Buy on Amazon
3 Dulcolax Pink Docusate Sodium Stool Softener Soft Gels Dulcolax 9.7 4.5 (4,295) Buy on Amazon
4 Dulcolax Stimulant Free Mint Liquid Laxative Dulcolax 9.7 4.5 (6,995) Buy on Amazon
5 GenCare Senna-S Natural Laxative and Stool Softener GENCARE GENERIC HEALTHCARE 9.7 4.5 (3,566) Buy on Amazon
6 GoodSense ClearLax Polyethylene Glycol 3350 Powder Good Sense 9.6 4.6 (710) Buy on Amazon
7 Rite Aid Col-Rite Stool Softener Softgels Rite Aid 9.6 4.6 (401) Buy on Amazon
8 Walgreens Senna-S Laxative Tablets Walgreens 9.6 4.6 (153) Buy on Amazon
9 Swan 100% Pure Castor Oil Stimulant Laxative Swan 9.4 4.4 (143) Buy on Amazon
10 Rite Aid Fast Relief Bisacodyl Laxative Suppositories Rite Aid 9.3 4.3 (161) Buy on Amazon
11 Walgreens Woman's Laxative Tablets Walgreens 9.3 4.7 (91) Buy on Amazon
12 Walgreens Laxative Pills, 90 Count Walgreens 7.1 4.7 (47) Buy on Amazon
13 GenCare Maximum Strength Senna Laxative Tablets GENCARE GENERIC HEALTHCARE 6.8 4.2 (52) Buy on Amazon
14 Walgreens Gentle Laxative Tablets Walgreens 6.2 4.8 (27) Buy on Amazon
15 Walgreens Maximum Strength Laxative Pills Walgreens 5.5 5.0 (9) Buy on Amazon
16 Sunmark Mineral Oil USP Lubricant Laxative - 16 oz, Pack of Sunmark 5.2 4.8 (8) Buy on Amazon
17 Generic Bisacodyl 10 MG Suppositories, 100 Count Generic 5.1 5.0 (1) Buy on Amazon
18 Walgreens Maximum Strength Laxative Pills Walgreens 4.4 4.3 (2) Buy on Amazon
19 Colace Regular Strength Docusate Sodium Stool Softener Colace 0.0 0.0 Buy on Amazon
20 Walgreens Ready-to-Use Saline Laxative Enema Walgreens 0.0 0.0 Buy on Amazon
21 Walgreens Senna Natural Vegetable Laxative Tablets Walgreens 0.0 0.0 Buy on Amazon