Best Similac Liquid Baby Formula in 2026

Daisy
Last Updated: Jul 18, 2026

At a Glance: Our Top Picks for Similac Liquid Baby Formula

Similac Alimentum with 2’-FL HMO Hypoallergenic Infant Formula, for Food Allergies and Colic, Suitable for Lactose Sensitivity, Ready-to-Feed Baby Formula, 32-fl-oz Bottle, Pack of 6
#TOP1
Similac Alimentum With 2’-Fl Hmo Hypoallergenic Infant Formula,
9.9
PM SCORE
Similac Advance Infant Formula with Iron, Ready-to-Feed Baby Formula, 32-fl-oz Bottle, Pack of 6
#TOP2
Similac Advance Infant Formula With Iron, Ready-To-Feed Baby
9.9
PM SCORE
Similac Sensitive Infant Formula, for Fussiness & Gas Due to Lactose Sensitivity, Ready-to-Feed Baby Formula, 32-fl-oz Bottle, Pack of 6
#TOP3
Similac Sensitive Infant Formula, For Fussiness & Gas
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Similac Liquid Baby Formula of 2026

Market Overview
Similac Liquid Baby Formula Reviewed
  • Reviews Analyzed: 19034 Items
  • PM Avg. Rating: 9.1 / 10
19 Products Evaluated
  • Highest Price: $178.50
  • Lowest Price: $20.93
  • Avg. Price: $55.11

Similac Alimentum With 2’-Fl Hmo Hypoallergenic Infant Formula, For Food Allergies And Colic, Suitable For Lactose Sensitivity, Ready-To-Feed Baby Formula, 32-Fl-Oz Bottle, Pack Of 6

SIMILAC
57512
14.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

HYPOALLERGENIC: Our formula is suitable for lactose sensitivity and has broken-down protein that is easy to digest for babies with food allergies or colic due to protein sensitivity

START FEELING BETTER TODAY: Similac Alimentum starts reducing colic symptoms due to protein sensitivity within 24 hours in most infants

WITH AN IMMUNE-NOURISHING INGREDIENT: First and only hypoallergenic formula with 2 -FL HMO, an immune-nourishing ingredient

EBT ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits in select stores; The SNAP name is a service mark of the US Department of Agriculture The USDA does not endorse any goods, services, or enterprises

Similac Advance Infant Formula With Iron, Ready-To-Feed Baby Formula, 32-Fl-Oz Bottle, Pack Of 6

SIMILAC
53363
3.94 X 3.27 X 8.35 Inches
2.00 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

EASY TO DIGEST: Similac infant formulas are nutritionally complete and inspired by breast milk

SUPPORTS BRAIN and EYE DEVELOPMENT: Features our exclusive blend of DHA, lutein, and vitamin E, ingredients found in breast milk that are important for helping support baby’s brain and eye development

NO PALM OLEIN OIL: Designed to support excellent calcium absorption

NO ARTIFICIAL GROWTH HORMONES: Similac was the first leading infant formula brand with no artificial growth hormones. It’s also kosher and halal

PREFERRED BRAND: Similac is the infant formula brand fed in hospitals

#TOP3

Similac Sensitive Infant Formula, For Fussiness & Gas Due To Lactose Sensitivity, Ready-To-Feed Baby Formula, 32-Fl-Oz Bottle, Pack Of 6

SIMILAC
AB-037C
10.63 X 8.19 X 8.69 Inches
14.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

DESIGNED FOR BABY’S FUSSINESS and GAS: Our sensitive formula for babies is specially designed for fussiness and gas due to lactose sensitivity

SUPPORTS BABY’S BRAIN and EYE DEVELOPMENT: Features our exclusive blend of DHA, lutein, and vitamin E, special ingredients found in breast milk that are important for helping to support baby’s brain and eye development

NO PALM OLEIN OIL: Designed to support excellent calcium absorption

PREFERRED BRAND: Similac is the infant formula brand fed in hospitals

NO ARTIFICIAL GROWTH HORMONES: Similac was the first leading infant formula brand with no artificial growth hormones

Similac 360 Total Care Infant Formula, With 5 Hmo Prebiotics, Our Closest Formula To Breast Milk, Non-Gmo, Baby Formula, Ready-To-Feed, 8 Fl Oz (Pack Of 24)

SIMILAC
68138
12.48 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

CLOSER TO BREAST MILK THAN EVER BEFORE: Similac 360 Total Care, our biggest formula breakthrough, has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk

360 WHOLE-BABY SUPPORT: Nutrition designed for immune support, brain development, and digestive health

HELPS STRENGTHEN THE IMMUNE SYSTEM: Similac 360 Total Care is designed to help strengthen baby’s immune system

CONVENIENT & READY TO USE: Great for on-the-go and late-night feeding; no mixing required

Similac 360 Total Care Sensitive Infant Formula, With 5 Hmo Prebiotics For Fussiness & Gas Due To Lactose Sensitivity, Non-Gmo, Baby Formula, Ready-To-Feed, 8 Fl Oz, Pack Of 24

SIMILAC
68157
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

OUR CLOSEST SENSITIVE FORMULA TO BREAST MILK THAN EVER BEFORE: Our biggest formula breakthrough for sensitive tummies is gentle nutrition designed to ease common tummy troubles like fussiness and gas due to lactose sensitivity

EXCLUSIVE BLEND OF PREBIOTICS: Similac 360 Total Care Sensitive has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk

360 WHOLE-BABY SUPPORT: Nutrition designed for immune support, brain development, and digestive health

CONVENIENT & READY TO USE: Great for on-the-go and late-night feeding; no mixing required

Similac Pure Bliss Infant Formula, Modeled After Breast Milk, Non-Gmo, 24.7 Oz

SIMILAC
67317
5.13 X 5.13 X 5.35 inches
1.54 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

MODELED AFTER BREAST MILK: Pure Bliss by Similac is thoughtfully crafted nutrition modeled after breast milk

NO COMPROMISE: With NO artificial growth hormones,antibiotics, or palm olein oil, and it’s non-GMO

FOR BRAIN & EYE DEVELOPMENT: Pure Bliss has DHA and ARA, key nutrients to support brain & eye development

FROM THE MAKERS OF SIMILAC: Thoughtfully crafted nutrition that starts with fresh milk from grass-fed cows

MAKES 188 (4-FL-OZ) BOTTLES: Four 24.7-oz can of Pure Bliss by Similac makes approximately 188 (4-fl-oz) bottles

Similac 360 Total Care Infant Formula With 5 Hmo Prebiotics, Our Closest Formula To Breast Milk, Non-Gmo, Baby Formula, Ready-To-Feed 32-Fl-Oz Bottle

SIMILAC
3.95 X 3.30 X 8.37 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

CLOSER TO BREAST MILK THAN EVER BEFORE: Similac 360 Total Care, our biggest formula breakthrough, has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk

360 WHOLE-BABY SUPPORT: Nutrition designed for immune support, brain development, and digestive health

HELPS STRENGTHEN THE IMMUNE SYSTEM: Similac 360 Total Care is designed to help strengthen baby’s immune system

NO ARTIFICIAL GROWTH HORMONES & NON-GMO§: Similac is the first leading infant formula brand with no artificial growth hormones; contains ingredients that are not genetically engineered

EBT ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits in select stores; The SNAP name is a service mark of the US Department of Agriculture; USDA does not endorse any goods, services, or enterprises

Similac 360 Total Care Infant Formula, With 5 Hmo Prebiotics, Our Closest Formula To Breast Milk, Non-Gmo, Baby Formula, Ready-To-Feed, 8-Fl-Oz Bottle (Pack Of 6) (Packaging May Vary)

SIMILAC
68138
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

CLOSER TO BREAST MILK THAN EVER BEFORE: Similac 360 Total Care, our biggest formula breakthrough, has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk

360 WHOLE-BABY SUPPORT: Nutrition designed for immune support, brain development, and digestive health

HELPS STRENGTHEN THE IMMUNE SYSTEM: Similac 360 Total Care is designed to help strengthen baby’s immune system

CONVENIENT & READY TO USE: Great for on-the-go and late-night feeding; no mixing required

RUSTED BRAND: Similac is the #1 infant formula brand chosen by parents

Similac Neosure Premature Post-Discharge Infant Formula, Ready-To-Feed Baby Formula, 32-Fl-Oz Bottle, Pack Of 6

SIMILAC
AB-039C
10.63 X 8.19 X 8.69 Inches
10.90 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

#1 PREMATURE INFANT FORMULA BRAND: And the #1 brand fed in the NICU

EXCELLENT CATCH-UP GROWTH: Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula

SUPPORTS BRAIN & EYE DEVELOPMENT: Has our unique blend of DHA, lutein, & vitamin E to support brain and eye development

HELPS SUPPORT BONE GROWTH: Our formula has calcium and phosphorus for baby’s growing bones

NO ARTIFICIAL GROWTH HORMONES: The first leading infant formula brand with no artificial growth hormones

Pure Bliss By Similac Infant Formula, Modeled After Breast Milk, Non-Gmo Baby Formula, 24.7 Ounces, (Pack Of 6)

SIMILAC
67590
17.56 X 11.68 X 7.13 Inches
1.54 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

MODELED AFTER BREAST MILK: Pure Bliss by Similac is thoughtfully crafted nutrition modeled after breast milk

NO COMPROMISE: With NO artificial growth hormones, antibiotics, or palm olein oil, and it’s non-GMO

FOR BRAIN & EYE DEVELOPMENT: Pure Bliss has DHA and ARA, key nutrients to support brain & eye development

FROM THE MAKERS OF SIMILAC: Thoughtfully crafted nutrition that starts with fresh milk from grass-fed cows

MAKES 282 (4-FL-OZ) BOTTLES: Six 24.7oz cans of Pure Bliss by Similac make approximately 282 (4-fl-oz) bottles

Similac 360 Total Care Sensitive Infant Formula, With 5 Hmo Prebiotics, For Fussiness And Gas Due To Lactose Sensitivity, Non-Gmo, Baby Formula, Ready-To-Feed, 8-Fl-Oz (Pack Of 6) (Packaging May Vary)

SIMILAC
68157
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

OUR CLOSEST SENSITIVE FORMULA TO BREAST MILK THAN EVER BEFORE: Our biggest formula breakthrough for sensitive tummies is gentle nutrition designed to ease common tummy troubles like fussiness and gas due to lactose sensitivity

EXCLUSIVE BLEND OF PREBIOTICS: Similac 360 Total Care Sensitive has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk

360 WHOLE-BABY SUPPORT: Nutrition designed for immune support, brain development, and digestive health

CONVENIENT & READY TO USE: Great for on-the-go and late-night feeding; no mixing required

EBT ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits in select stores; The SNAP name is a service mark of the US Department of Agriculture; USDA does not endorse any goods, services, or enterprises

Amazon Brand - Mama Bear Sensitivity Baby Formula Powder With Iron, Reduced Lactose, Non-Gmo, 2'-Fl Hmo For Immune Support, 22.5 Ounce

MAMA BEAR
4.58 X 6.72 X 5.33 Inches
1.41 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

COMPLETE NUTRITION: Mama Bear Sensitivity Baby Formula has 99 percent less lactose than standard milk-based infant formula and provides complete nutrition for our little ones ages 0-12 months; Compare to Similac Pro-Sensitive Infant Formula

IMMUNE SUPPORT: Mama Bear Sensitivity Baby Formula has 2'-FL HMO, a prebiotic commonly found in breast milk, which aids growth of beneficial bacteria in baby's digestive tract for infant immune support

GROWTH AND DEVELOPMENT: Mama Bear Sensitivity contains Lutein and Vitamin E, plus DHA, an Omega-3 fat important in brain and eye development; Reduced-lactose; Gluten free; Sensitivity meets baby's complete nutrition needs for the first year of life

LOWER LACTOSE LEVEL: Not only is Mama Bear Sensitivity reduced-lactose, it's a non-GMO baby formula with ingredients that are not genetically engineered and no artificial growth hormones

BABY NUTRITION: Mama Bear Sensitivity Baby Formula meets the same FDA and quality standards as the national brand; Parents can be confident in choosing Mama Bear Sensitivity as a breast milk alternative

Similac Advance Infant Formula With Iron, Baby Formula Powder, 30.8-Oz Can

SIMILAC
59797
5.13 X 5.13 X 6.50 Inches
2.23 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

EASY TO DIGEST: Similac infant formulas are nutritionally complete and inspired by breast milk

SUPPORTS BRAIN & EYE DEVELOPMENT: Features our exclusive blend of DHA, lutein, and vitamin E, ingredients found in breast milk that are important for helping support baby’s brain and eye development

NO PALM OLEIN OIL: Designed to support excellent calcium absorption

NO ARTIFICIAL GROWTH HORMONES: Similac was the first leading infant formula brand with no artificial growth hormones. It’s also kosher and halal

PREFERRED BRAND: Similac is the #1 infant formula brand fed in hospitals

Similac is the first leading infant formula brand with no artificial growth hormone (no significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows)

Similac Advance Infant Formula With Iron, Ready-To-Feed Baby Formula, 32-Fl-Oz Bottle

SIMILAC
53363
3.94 X 3.27 X 8.35 Inches
2.00 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

EASY TO DIGEST: Similac infant formulas are nutritionally complete and inspired by breast milk

SUPPORTS BRAIN & EYE DEVELOPMENT: Features our exclusive blend of DHA, lutein, and vitamin E, ingredients found in breast milk that are important for helping support baby’s brain and eye development

NO PALM OLEIN OIL: Designed to support excellent calcium absorption

NO ARTIFICIAL GROWTH HORMONES: Similac was the first leading infant formula brand with no artificial growth hormones. It’s also kosher and halal

PREFERRED BRAND: Similac is the #1 infant formula brand fed in hospitals

#TOP15

Similac Alimentum With 2’-Fl Hmo Hypoallergenic Infant Formula, For Food Allergies And Colic, Suitable For Lactose Sensitivity, Ready-To-Feed Baby Formula, 2-Fl-Oz Bottle, Pack Of 48

SIMILAC
67637
14.88 X 10.88 X 4.56 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

HYPOALLERGENIC: Our formula is suitable for lactose sensitivity and has broken-down protein that is easy to digest for babies with food allergies or colic due to protein sensitivity

START FEELING BETTER TODAY: Similac Alimentum starts reducing colic symptoms due to protein sensitivity within 24 hours in most infants*

WITH AN IMMUNE-NOURISHING INGREDIENT: First and only hypoallergenic formula with 2’-FL HMO, an immune-nourishing ingredient

EBT ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits in select stores; The SNAP name is a service mark of the US Department of Agriculture The USDA does not endorse any goods, services, or enterprises

#TOP16

Similac Organic Infant Formula With Iron, Ready To Feed, 2 Fl Oz Bottles (Pack Of 48)

SIMILAC
67634
14.88 X 10.88 X 4.56 Inches
10.08 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

48 BOTTLES: Get a total of 48 2 fl oz bottles of Similac Organic Ready-to-Feed formula

NEW AND IMPROVED: Infant formula, modeled after breast milk; made with lactose

ORGANIC FORMULA: Easy-to-digest baby formula that’s USDA-certified organic

NO PALM OLEIN OIL: Similac Organic has no palm olein oil and no artificial growth hormones,* and it’s non-GMO**

SUPPORTS BRAIN AND EYE DEVELOPMENT: Exclusive blend of DHA, lutein, and vitamin E, nutrients found in breast milk

Amazon Brand - Mama Bear Complete Comfort Infant Formula Milk-Based Powder With Iron, 1.41 Pound, 22.5 Ounce

MAMA BEAR
5.19 X 5.19 X 4.88 Inches
1.41 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

LESS GAS, LESS FUSSY: Babies deserve to be comfortable; gas & crying isn't comfortable. Consider a switch to Mama Bear Complete Comfort Baby Formula with Iron and 2'-FL HMO. Compare to Similac Pro-Total Comfort.*

COMPLETE NUTRITION: Mama Bear Complete Comfort Baby Formula contains nutrients like those found in breast milk: DHA (Omega-3), Lutein & Vitamin E, to support growth, brain & eye development & 2'-FL HMO, a prebiotic for digestive & immune support.

COMPLETE NUTRITION: Mama Bear Complete Comfort Baby Formula contains nutrients like those found in breast milk: DHA (Omega-3), Lutein & Vitamin E, to support growth, brain & eye development & 2'-FL HMO, a prebiotic for digestive & immune support.

EASY TO DIGEST: Sometimes babies need a little help from an infant formula that's easier to digest. Mama Bear Complete Comfort Baby Formula contains special proteins that are gentle on delicate tummies to reduce fussiness, gas & crying.

FDA STANDARDS: Like all infant formulas sold in the U.S., Mama Bear Complete Comfort meets FDA requirements, the same as the national brand.

Similac Advance Kosher Infant Formula With Iron, 2 Fl Oz - 4 Bottles (2 Pack = 8 Bottles) Milk Based, Ready To Feed, Resealable Bottle, Cholov Yisroel, (0-12 Months)

SIMILAC
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
K O L 9.95

Features

BADATZ-CERTIFIED: The first and only Badatz-certified infant formula available in the US (Cholov Yisroel)

TRUSTED FORMULA: Similac has been giving babies a strong start over 90 years. It’s the #1 infant formula brand fed in hospitals.

NUTRIENTS: Similac Advance has DHA and ARA for brain & eye development, vitamin E to support developing cells, and Calcium & vitamin D for strong bones.

KOSHER: Certified kosher (also for Passover), Gluten-Free, palm olein oil-free, which allows for excellent Calcium absorption.

BULK & INDIVIDUAL OPTIONS: Also available in 32oz bottles. Not for infants or children with galactosemia.

Similac Soy Isomil Infant Formula With Iron, Ready To Feed, 1 Qt (Pack Of 4)

SIMILAC
8.19 X 6.81 X 9.00 inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

REDUCES FUSSINESS & GAS: Soy-based formulas have been clinically shown to help reduce common feeding problems such as fussiness & gas

VEGETARIAN-FRIENDLY: For infants of families who follow a vegetarian or plant-based diet

NUCLEOTIDES: To help support the immune system

PREBIOTICS: For digestive health

HELPS SUPPORT BRAIN & EYES: Has DHA and lutein, important ingredients found in breast milk

NO PALM OLEIN OIL: Designed to support excellent calcium absorption

PREFERRED BRAND: Similac is the #1 infant formula brand fed in hospitals

Top 10 liquid baby formula Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Similac 17
Mama Bear 2

Top 10 liquid baby formula Brands Pie Chart


We've carried out a comprehensive analysis of 19,034 reviews on liquid baby formula, using our selection criteria to identify the best options in the baby & toddler feeding supplies. Our findings reveal that most customers typically select liquid baby formula priced around $55.11, with top brands including aptamil, similac, enfamil, enfamil prenatals & baby vitamins, garden of life, gerber, aussie bubs, smartypants and attitude and mommy's bliss

Our team of expert editors reviewed these high-quality items and handpicked the top 19 liquid baby formula for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the baby & toddler feeding supplies category. These include amazon.com, instock distributing, k o l and parapharma tech and kabrita usa .

We are dedicated to assisting our users in finding the right formula Products based on their needs, saving them considerable time when choosing which liquid baby formula to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.