PickSmartly Review

Best Sodium Fluoride Mouthwashes in 2026

10.0 PM Score
Products Evaluated
16
Reviews Analyzed
45,604
Brands Ranked
7
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Maintaining oral hygiene goes far beyond the simple act of brushing and flossing. For many, the final step in a preventative dental routine involves a therapeutic rinse designed to fortify tooth enamel and combat the acid-producing bacteria that lead to decay. Sodium fluoride mouthwashes serve as a specialized tool in this arsenal, providing a concentrated dose of minerals that can reach the interproximal spaces—those tight gaps between teeth—where a toothbrush might struggle to penetrate. Unlike standard cosmetic mouthwashes that focus primarily on breath freshening, fluoride rinses are functional health products aimed at remineralization and cavity prevention.

Editor's Choice

Our Top Picks for Sodium Fluoride Mouthwashes

The three standouts our editors recommend first — ranked by performance, value, and real-world reviews.

Listerine Smart Rinse Mouthwash, Children's Zero Alcohol, Fluoride Rinse, Anti Cavity Mouth Rinse, Bad Breath Treatment, Mouthwash for Kids. Bubblegum...

Listerine Smart Rinse Bubblegum Kids Mouthwash

4.8 (17,070 ratings)
LISTERINE 312547115803 3.30 Pounds

Reviews for LISTERINE (PM Score)

10.0 PM Score
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  • KIDS MOUTHWASH: Listerine Smart Rinse Mouthwash helps to strengthen and protect teeth against cavities when used as part of your regular oral hygiene routine. Alcohol Free Formula. Bubblegum flavor.
  • FLUORIDE RINSE: Kids mouthwash with fluoride is formulated with not only sodium fluoride but also acidulated phosphate to clean the mouth beyond brushing alone. Helps to prevent cavities in hard to reach places that brushing may miss.
  • BAD BREATH TREATMENT: Listerine mouthwash is infused with a bubblegum flavor that leaves your mouth feeling clean and freshens breath after only one use. Anticavity mouthwash in a fun bubblegum flavor designed for kids.
  • ALCOHOL Free FORMULA: Smart Rinse zero alcohol mouthwash offers 2x stronger teeth for better dental cavity protection. Accepted by the American Dental Association (ADA) to help prevent cavities.
  • INCLUDES: Pack of 3, 16.9 Fl. Oz each mouthwash. Use regularly during your oral care routine to help contribute to overall good oral hygiene. Rinse for 60 seconds both morning and night or otherwise instructed by a dentist or physician.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Listerine Smart Rinse Mouthwash turns a chore into a treat with its kid-friendly bubblegum flavor. We found that this alcohol-free formula is a game-changer for parents worried about the harsh sting of traditional rinses. By combining sodium fluoride with acidulated phosphate, it reaches those tricky, hard-to-access spots that a toothbrush might miss, helping to build stronger teeth against cavities. It is ADA-accepted, which provides that extra layer of professional confidence during a morning or nightly routine. Since it comes in a convenient three-pack, you can keep the bathroom cabinet stocked for a long time. It effectively freshens breath after just one use, making it a reliable staple for maintaining healthy oral hygiene in children.

What We Like
Zero alcohol formula
Bubblegum flavor
Fluoride cavity protection
ADA accepted
Three bottle pack

Listerine Naturals Enamel Repair Mouthwash with Mineral Sodium Fluoride, Oral Rinse to Help Restore Tooth Enamel & Kill Bad Breath Germs, 99% Naturall...

Listerine Naturals Enamel Repair Herbal Mint Mouthwash

4.6 (12,197 ratings)
LISTERINE 1

Reviews for LISTERINE (PM Score)

9.9 PM Score
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  • Listerine Naturals is no longer available: We recommend you try Listerine Fresh Burst, which is formulated with 4 essential oils that is inspired by nature.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
M&C Company 9.89 Yes Yes Yes

Weakened tooth enamel and persistent bad breath are the primary culprits this rinse aims to tackle. I spent some time testing this herbal mint formula, which utilizes mineral sodium fluoride to help restore your enamel while aggressively targeting the germs that cause odor. It feels like a more balanced approach to oral care because it leans heavily on a 99% naturally derived composition. While this specific Naturals line is actually being phased out, the brand suggests pivoting to the Fresh Burst version, which uses four essential oils inspired by nature to achieve similar results. If you are looking for a way to maintain your enamel integrity without harsh synthetic profiles, this is a solid choice for your daily routine.

What We Like
Enamel repair formula
99% naturally derived
Herbal mint flavor
Kills bad breath
Mineral sodium fluoride
#3

PerioSciences - Mouthwash Oral Care Pre Brush (Sensitive)

PerioSciences AO ProRinse Antioxidant Mouthwash for Sensitive Gums

4.6 (1,096 ratings)
PERIOSCIENCES 10242 2.25 X 7.50 X 2.25 Inches

Reviews for PERIOSCIENCES (PM Score)

9.8 PM Score
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  • ANTIOXIDANTS SUPPORT NATURAL DEFENSES - A combination of PerioSciences’ signature antioxidants and minerals, botanicals and other moisturizers supports your saliva’s natural defenses and is ideally suited for extreme oral sensations
  • NATURAL INGREDIENTS - This Mouthwash contains a combination of plant extracts that freshen breath, keeps teeth clean and moisturizes dry oral tissue, resulting in improved appearance of the tissue & a pleasant and fresh feeling in the mouth. FREE OF fluoride, alcohol, sodium lauryl sulfate (SLS), parabens, and artificial colors
  • GREAT FOR GUM HEALTH - Cool and flavorful, this Mouthwash will freshen breath while soothing soft tissue in the oral cavity resulting in improved appearance of tissue and a pleasant, fresh feeling in the mouth
  • DENTIST RECOMMENDED - Scientifically proven ingredients with antibacterial properties focusing on the mouth's natural defense system to reduce plaque, promote healthier teeth and gums
  • FIRST IN ITS CLASS - AO ProRinse oral wash is first in a new category of antioxidant oral care and works synergistically with naturally occurring salivary antioxidants. For best results, use with AO ProToothpaste and AO ProVantage Dental Gel
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
PerioSciences 9.76 Yes Yes Yes

Most people settle for harsh, alcohol-based rinses that strip the mouth of moisture, but PerioSciences takes a much smarter approach by working with your body's biology. This antioxidant-driven mouthwash is a standout because it doesn't just mask bad breath. It actually supports your saliva's natural defenses using a signature blend of minerals and botanicals. I found that it feels incredibly soothing on sensitive oral tissues rather than stinging like traditional drugstore brands. Because it is completely free of fluoride, alcohol, and SLS, it provides a gentle yet effective way to reduce plaque and freshen your breath. It’s a sophisticated, dentist-recommended option for anyone looking to move beyond basic hygiene and toward true oral wellness.

What We Like
Antioxidant oral defense
Alcohol-free formula
Soothes sensitive tissue
Natural plant extracts
Reduces plaque buildup
#4

Natures Answer Periobrite Mouthwash 16 oz | Whitens Teeth | Freshens Breath | Removes Plaque | Minimizes Dry Mouth

Nature's Answer PerioBrite Alcohol-Free Mouthwash

4.6 (1,222 ratings)
NATURE'S ANSWER 083000016431 7.50 X 2.50 X 2.50 Inches 1.00 Pounds

Reviews for NATURE'S ANSWER (PM Score)

9.8 PM Score
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  • Dentist Formulated with Ingredients, Supports Healthy Teeth & Gums*. Fights Bad Breath with Organic Herbs, CoQ10, Olive Leaf, & Folic Acid, Great Tasting & Alcohol-Free. No Sodium-Lauryl-Sulfate, No Artificial Sweeteners or Preservatives, Soy Free, Vegetarian.
  • PerioBrite Mouthwash Alcohol Free Cool Mint Formulated by a Dentist, Nature’s Answer PerioBrite Mouthwash does more than keep breath fresh and clean, it promotes periodontal health, which is important for a healthy mouth.* In fact, daily cleansing and rinsing with PerioBrite helps promote healthy teeth and gums without the concerns about fluoride, because it’s fluoride free.*
  • Only PerioBrite Mouthwash contains a unique combination of soothing organic wildcrafted herbs, well-known for their cleansing action, together with Co-Q10, Folic Acid, Oregano, Cinnamon and Clove to support tissue and gum health.*
  • It moistens gum tissue for long-lasting results when used as part of an oral health program.* And since PerioBrite Mouthwash and alcohol free it fights bad breath and relieves dry mouth, energizing your mouth with a cool, sparkling minty-fresh feeling.*
  • Nature’s Answer Unique Bio-Chelation process. Only Nature’s Answer uses a unique Bio-Chelation process, developed by the company’s founder and owner. It includes “cold extraction.” Cold extraction, allows the raw plant materials to be extracted without being exposed to heat, capturing and preserving the holistic balance of the herbs in Nature’s Answer PerioBrite Mouthwash.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Greenwald Brands 9.93 Yes Yes Yes

People struggling with chronic dry mouth or sensitive gums need to ditch their stinging, alcohol-heavy rinses for Nature's Answer PerioBrite. This dentist-formulated mouthwash feels completely different because it prioritizes gum health through a sophisticated blend of CoQ10, Folic Acid, and organic wildcrafted herbs like oregano and clove. I was particularly impressed by their unique Bio-Chelation cold extraction process, which preserves the holistic integrity of the plant materials without using heat. It provides a refreshing, cool minty sensation that actually moistens your gum tissue rather than drying it out. Since it is fluoride-free and avoids artificial sweeteners or sodium-lauryl-sulfate, it offers a much cleaner, vegetarian-friendly way to maintain periodontal health and brighten your smile daily.

What We Like
Alcohol-free formula
Supports gum health
Cold extraction process
Moisturizes gum tissue
Organic herbal blend

Essential Oxygen Certified BR Organic Brushing Rinse, All Natural Mouthwash for Whiter Teeth, Fresher Breath, and Happier Gums, Alcohol-Free Oral Care...

Essential Oxygen Organic Brushing Rinse Wintergreen

4.6 (4,529 ratings)
ESSENTIAL OXYGEN 3.75 X 3.75 X 7.75 Inches 2.00 Pounds

Reviews for ESSENTIAL OXYGEN (PM Score)

9.8 PM Score
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  • Contains 1-32 fl. oz bottle of Organic Mouthwash
  • It Works! Premier Oral Care for whitening, breath freshening and removing bad breath germs with the power of hydrogen peroxide, aloe and organic essential oils. Learn more at YouTube: Essential Oxygen Brushing Rinse
  • It's Clean! All natural and free of alcohol, fluoride, glycerin, sugars or sodium lauryl sulfate or anything objectionable!
  • It's Planet Positive! Our oxygen-based formula makes grass greener and oceans cleaner.
  • Woman owned, NON GMO, vegan, gluten-free, BPA-free packaging, no animal testing and community giving
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Traditional mouthwashes often rely on harsh alcohols that strip your mouth of moisture, but Essential Oxygen takes a much gentler, oxygen-based approach to oral hygiene. I was impressed by how this formula utilizes hydrogen peroxide, aloe, and organic essential oils to tackle bad breath germs without the stinging sensation of typical rinses. It feels incredibly clean because it avoids the usual offenders like fluoride, glycerin, and sodium lauryl sulfate. The wintergreen flavor provides a refreshing kick that actually makes you feel like your teeth are getting a deep clean. Beyond just whitening and freshening breath, it is reassuring to see a woman-owned, vegan brand that prioritizes non-GMO ingredients and eco-friendly, BPA-free packaging for a more mindful daily routine.

What We Like
Oxygen-based formula
Alcohol-free rinse
Organic essential oils
Vegan and non-GMO
Whitens teeth naturally

CariFree Maintenance Rinse (Mint): Fluoride Mouthwash | Dentist Recommended Anti-Cavity Oral Care | Neutralizes pH | Freshen Breath | Cavity Preventio...

CariFree Maintenance Mint Fluoride Mouthwash

4.6 (3,520 ratings)
CARIFREE 1 2.25 X 2.25 X 8.12 Inches

Reviews for CARIFREE (PM Score)

9.8 PM Score
Buy on Amazon
  • [WIN THE BATTLE AGAINST TOOTH DECAY]: Do you ever wonder why some of us continue to get cavities despite meticulous oral hygiene, whereas others who rarely brush and floss do not? The risk of cavities varies from person to person and is based on eating and drinking habits, hygiene (brushing and flossing), saliva flow, as well as other factors. *NEW LOOK, same great formula! Formally known as CariFree CTx3 Rinse*
  • [PROTECT YOUR ENAMEL]: The CariFree Maintenance Rinse contains 0.05% sodium fluoride, which helps prevent tooth decay and white spots. Evidence shows that fluoride strengthens your teeth and aids in the prevention of dental cavities.
  • [NEUTRALIZE pH] Studies suggest that decay is a function of low pH. Maintaining an elevated or neutral pH balance helps to keep your tooth enamel and smile healthy. The CariFree Maintenance Rinse is alcohol-free and contains patented pH+ technology to elevate the pH in your mouth, keeping it balanced. U.S. Patent No. 9,427,384 & 10,143,633.
  • [FORMULATED WITH XYLITOL]: The Maintenance Rinse contains 25% xylitol! Xylitol is a naturally occurring, sweet-tasting ingredient found in many types of plants. Research shows that regular use of xylitol-rich products may reduce your risk of dental cavities.
  • [DENTIST-RECOMMENDED MOUTHWASH] Maintaining proper dental hygiene and cavity prevention is essential to a happy and healthy smile! The dentist recommended Maintenance Rinse fluoride mouthwash actively works to prevent cavities, freshen breath, and elevate pH.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
CariFree 9.86 Yes Yes Yes

Why do some people struggle with constant cavities despite perfect brushing habits? The answer often lies in the chemistry of your mouth, and that is exactly where CariFree Maintenance Rinse steps in to balance the scales. Unlike standard mouthwashes that just mask odors, this formula uses patented pH+ technology to neutralize acidity and protect your enamel from decay. I was particularly impressed by the inclusion of 25% xylitol, a natural ingredient that works alongside the 0.05% sodium fluoride to actively strengthen teeth and prevent white spots. It is alcohol-free and carries a refreshing mint flavor that leaves your breath clean without that harsh, stinging sensation. It feels like a professional-grade tool for anyone serious about long-term oral health.

What We Like
Patented pH+ technology
25% xylitol content
Alcohol-free formula
Strengthens tooth enamel
Prevents dental decay
#7

CariFree Maintenance Rinse (Mint): Fluoride Mouthwash | Dentist Recommended Anti-Cavity Oral Care | Neutralizes pH | Freshen Breath | Cavity Preventio...

CariFree Maintenance Mint Fluoride Mouthwash

4.7 (304 ratings)
CARIFREE 1

Reviews for CARIFREE (PM Score)

9.7 PM Score
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  • [WIN THE BATTLE AGAINST TOOTH DECAY]: Do you ever wonder why some of us continue to get cavities despite meticulous oral hygiene, whereas others who rarely brush and floss do not? The risk of cavities varies from person to person and is based on eating and drinking habits, hygiene (brushing and flossing), saliva flow, as well as other factors. *NEW LOOK, same great formula! Formally known as CariFree CTx3 Rinse*
  • [PROTECT YOUR ENAMEL]: The CariFree Maintenance Rinse contains 0.05% sodium fluoride, which helps prevent tooth decay and white spots. Evidence shows that fluoride strengthens your teeth and aids in the prevention of dental cavities.
  • [NEUTRALIZE pH] Studies suggest that decay is a function of low pH. Maintaining an elevated or neutral pH balance helps to keep your tooth enamel and smile healthy. The CariFree Maintenance Rinse is alcohol-free and contains patented pH+ technology to elevate the pH in your mouth, keeping it balanced. U.S. Patent No. 9,427,384 & 10,143,633.
  • [FORMULATED WITH XYLITOL]: The Maintenance Rinse contains 25% xylitol! Xylitol is a naturally occurring, sweet-tasting ingredient found in many types of plants. Research shows that regular use of xylitol-rich products may reduce your risk of dental cavities.
  • [DENTIST-RECOMMENDED MOUTHWASH] Maintaining proper dental hygiene and cavity prevention is essential to a happy and healthy smile! The dentist recommended Maintenance Rinse fluoride mouthwash actively works to prevent cavities, freshen breath, and elevate pH.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
CariFree 9.86 No No No

Perfect oral hygiene doesn't actually guarantee a cavity-free life, as individual saliva flow and dietary habits play massive roles in dental health. CariFree Maintenance Rinse addresses this biological complexity by moving beyond simple cleaning to actively managing your mouth's chemical environment. It uses patented pH+ technology to neutralize acidity, which is crucial since decay thrives in low-pH settings. I found the 25% xylitol concentration particularly impressive, as this natural ingredient works alongside the 0.05% sodium fluoride to strengthen enamel and prevent white spots. Unlike many harsh rinses, this alcohol-free mint formula feels refreshing rather than stinging, making it a practical tool for anyone looking to elevate their preventative dental routine through science-backed pH balancing.

What We Like
Patented pH+ technology
High xylitol content
Strengthens tooth enamel
Alcohol-free formula
Neutralizes mouth acidity

Prevention Oncology Mouthwash, Non-Alcohol, 16oz, Prevention Oncology Mouth Rinse | Alcohol Free - Specially Formulated for Patients Undergoing Oncolo...

Prevention Oncology Non-Alcoholic Mouth Rinse

4.4 (1,689 ratings)
PREVENTION 742582036601 2.00 X 2.75 X 7.88 Inches 1.00 Pounds

Reviews for PREVENTION (PM Score)

9.6 PM Score
Buy on Amazon
  • Oncology Specific Formulation - Prevention Health Sciences’ over-the-counter (OTC) oncology mouth rinse has been formulated for use by patients going through chemo and radiation therapies. These treatments can result in uncomfortable mouth sores, ulcers, dry mouth, and other oral complications. This gentle mouth rinse is recommended and distributed by physicians to help soothe, alleviate, and control these side-effects, while also protecting the mucosal lining.
  • Soothes and Protects - Unlike other mouthwash and rinse products that contain alcohol and other additives, our solution is fluoride-, alcohol- and dye-free. The highly effective formulation of low concentration hydrogen peroxide, sodium citrate, zinc, and glycerin protects and soothes. It provides temporary pain relief to irritated areas of the mouth, lips, and throat, and rehydrates and moisturizes the oral cavity to alleviate dry mouth symptoms.
  • Oral Health Support - The addition of soothing natural menthol and peppermint oil will leave your mouth with a long-lasting clean and refreshed feel.
  • Safe and Easy To Use - This mouth rinse is safe for all ages and easy to use and administer. Early and regular use will aid in protecting against dry mouth and uncomfortable oral complications, and help in the healing process of current mouth sores and ulcers. We recommend rinsing 3-5 times a day when undergoing chemotherapy and/or radiation treatments. Adults and children ages 2 and older should gargle or swish around in the mouth for one minute, then spit out.
  • Prevention Health Sciences - We believe that good oral health begins with prevention. We provide a line of oral rinses and mouthwashes that are free of harsh chemicals and ingredients, always naturally flavored, and dye- and alcohol-free. We also offer fluoride free options! Our line of oral care products are recommended by health care professionals for both oncology related oral issues as well as every day care and protection. We provide preventative solutions for proper oral health care!
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
PHS Brands 9.84 Yes Yes Yes

Prevention Oncology Mouthwash provides specialized, gentle relief for patients navigating the difficult side effects of chemotherapy and radiation. Instead of the stinging sensation found in standard oral care, this formula uses a soothing blend of zinc, glycerin, and low-concentration hydrogen peroxide to protect the mucosal lining and calm mouth sores. It is a thoughtful, alcohol-free, and dye-free solution that prioritizes comfort when the mouth is most vulnerable. I found the addition of natural menthol and peppermint oil particularly helpful, as it offers a refreshing clean without the harshness of traditional rinses. Whether you are managing dry mouth or trying to aid the healing of ulcers, this rinse acts as a vital tool for maintaining oral comfort during intensive medical treatments.

What We Like
Alcohol and dye-free
Soothes mouth sores
Rehydrates dry mouth
Natural peppermint oil
Oncology specific formula

CariFree Maintenance Rinse (Citrus): Fluoride Mouthwash | Dentist Recommended Anti-Cavity Rinse | Xylitol | Neutralizes pH | Freshen Breath | Cavity P...

CariFree Citrus Maintenance Fluoride Mouthwash

4.6 (910 ratings)
CARIFREE 01 2.25 X 2.25 X 8.12 Inches 1.24 Pounds

Reviews for CARIFREE (PM Score)

9.6 PM Score
Buy on Amazon
  • [WIN THE BATTLE AGAINST TOOTH DECAY]: Do you ever wonder why some of us continue to get cavities despite meticulous oral hygiene, whereas others who rarely brush and floss do not? The risk of cavities varies from person to person and is based on eating and drinking habits, hygiene (brushing and flossing), saliva flow, as well as other factors. *NEW LOOK, same great formula! Formally known as CariFree CTx3 Rinse*
  • [PROTECT YOUR SMILE]: CariFree Citrus Maintenance Rinse contains 0.05% sodium fluoride, which helps prevent tooth decay and white spots. Evidence shows that fluoride strengthens your teeth and aids in the prevention of dental cavities.
  • [NEUTRALIZE pH] Studies suggest that tooth decay is a function of low pH. Maintaining an elevated or neutral pH balance helps to keep your tooth enamel and smile healthy. CariFree Maintenance Rinse is alcohol-free and contains patented pH+ technology to elevate the pH in your mouth, keeping it balanced. U.S. Patent No. 9,427,384 & 10,143,633.
  • [FORMULATED WITH XYLITOL]: Maintenance Rinse contains 25% xylitol! Xylitol is a naturally occurring, sweet-tasting ingredient found in many types of plants. Research shows that regular use of xylitol-rich products may reduce your risk of dental cavities.
  • [DENTIST-RECOMMENDED MOUTHWASH] Maintaining proper dental hygiene and cavity prevention is essential to a happy and healthy smile! The dentist recommended Maintenance Rinse fluoride mouthwash actively works to prevent cavities, freshen breath, and elevate pH.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
CariFree 9.86 Yes Yes Yes

Chronic cavity sufferers and anyone struggling with enamel sensitivity need to stop relying on basic drugstore rinses and switch to CariFree Maintenance Rinse. I found that most mouthwashes just mask bad breath, but this formula actually tackles the root cause of decay by utilizing patented pH+ technology to neutralize oral acidity. It contains a heavy-hitting 25% xylitol concentration alongside 0.05% sodium fluoride, which works together to strengthen enamel and prevent those frustrating white spots. Since it is alcohol-free, you get a refreshing citrus taste without that harsh, stinging sensation that usually follows a deep clean. It feels like a professional-grade tool for anyone trying to break the cycle of constant dental fillings through proactive, science-backed pH balancing.

What We Like
25% xylitol content
Neutralizes oral pH
Alcohol-free formula
Strengthens tooth enamel
Prevents white spots

:Listerine Healthy White Restoring Fluoride Mouthwash, Anticavity Mouthwash Rinse for Teeth Whitening, Bad Breath, Enamel Restoration and Cavity Preve...

Listerine Healthy White Restoring Fluoride Mouthwash

4.6 (758 ratings)
LISTERINE 312547425926

Reviews for LISTERINE (PM Score)

9.6 PM Score
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  • 32-fluid ounce bottle of Listerine Healthy White Restoring Fluoride Whitening Mouthwash combines the power of an anticavity mouthwash with the stain-removing properties of a teeth whitener for a healthy, bright smile
  • Daily whitening oral rinse is formulated with sodium fluoride and hydrogen peroxide and safely removes stains from teeth when used regularly for a bright, healthy smile
  • Rebuilds 2x stronger enamel vs brushing alone, according to a lab study, for stronger teeth versus brushing alone. Anticavity mouthwash is made with fluoride to help prevent cavities and tooth decay
  • Anticavity mouthwash with a refreshing mint flavor helps prevent cavities or tooth decay as it cleans your entire mouth and kills bad breath germs
  • Incorporate this fluoride mouthwash into your daily oral care routine by rinsing for 60 seconds twice per day in the morning and evening
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Itty Bitty Goods 5.56 No No No

Coffee drinkers and tea lovers who struggle with stubborn surface stains absolutely require this dual-action rinse to maintain a bright smile. This Listerine formula goes far beyond basic breath freshening by combining hydrogen peroxide with sodium fluoride to tackle discoloration while simultaneously reinforcing your oral defenses. I found that incorporating this into a twice-daily, sixty-second routine provides a level of enamel protection that brushing alone simply cannot match, as it is lab-proven to rebuild enamel twice as strongly. The clean mint flavor leaves your mouth feeling incredibly refreshed without the overwhelming sting of harsher rinses. It is a highly efficient way to manage both whitening and cavity prevention in one easy step.

What We Like
Removes surface stains
Rebuilds enamel strength
Prevents tooth decay
Refreshing mint flavor
Dual-action formula
#11

Prevention Oncology Mouth Rinse | Alcohol Free - Specially Formulated for Patients Undergoing Oncology Treatment, Value 2-Pack

Prevention Oncology Alcohol-Free Mouth Rinse Value Pack

4.6 (568 ratings)
PREVENTION ONCOLOGY2PK

Reviews for PREVENTION (PM Score)

9.6 PM Score
Buy on Amazon
  • ONCOLOGY SPECIFIC FORMULATION: Prevention Health Sciences’ over-the-counter (OTC) oncology mouth rinse has been formulated for use by patients going through chemo and radiation therapies. These treatments can result in uncomfortable mouth sores, ulcers, dry mouth, and other oral complications. This gentle mouth rinse is recommended and distributed by physicians to help soothe, alleviate, and control these side-effects, while also protecting the mucosal lining.
  • SOOTHES & PROTECTS: Unlike other mouthwash and rinse products that contain alcohol and other additives, our solution is fluoride-, alcohol- and dye-free. The highly effective formulation of low concentration hydrogen peroxide, sodium citrate, zinc, and glycerin protects and soothes. It provides temporary pain relief to irritated areas of the mouth, lips, and throat, and rehydrates and moisturizes the oral cavity to alleviate dry mouth symptoms.
  • ORAL HEALTH SUPPORT: The addition of soothing natural menthol and peppermint oil will leave your mouth with a long-lasting clean and refreshed feel.
  • SAFE & EASY-TO-USE: This mouth rinse is safe for all ages and easy to use and administer. Early and regular use will aid in protecting against dry mouth and uncomfortable oral complications, and help in the healing process of current mouth sores and ulcers. We recommend rinsing 3-5 times a day when undergoing chemotherapy and/or radiation treatments. Adults and children ages 2 and older should gargle or swish around in the mouth for one minute, then spit out.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
PHS Brands 9.85 Yes Yes Yes

Patients navigating the grueling side effects of chemotherapy or radiation require a specialized oral care solution that prioritizes comfort over aggressive cleaning. This Prevention Oncology mouth rinse is a vital tool for managing the painful mouth sores, ulcers, and chronic dryness that often accompany intensive medical treatments. Because it is entirely free of alcohol, fluoride, and dyes, it avoids the stinging sensation typical of standard mouthwashes. Instead, the combination of low-concentration hydrogen peroxide, zinc, and glycerin works to protect the mucosal lining while providing much-needed rehydration. The addition of natural peppermint oil offers a gentle, refreshing sensation without irritation. Using this three to five times daily can significantly aid the healing process and help maintain oral health during a very difficult time.

What We Like
Alcohol-free formula
Soothes mouth sores
Rehydrates dry mouth
Protects mucosal lining
Gentle peppermint scent

Desert Essence Coconut Oil Mouthwash 16 fl oz Non-GMO, Gluten Free, Vegan, Cruelty Free, Sugar Free, Alcohol Free - Coconut Oil & Zinc Citrate - Eco-H...

Desert Essence Coconut Mint Mouthwash with Tea Tree Oil

DESERT ESSENCE 3436NDE 3.00 X 2.50 X 8.50 Inches 1.00 Pounds

Reviews for DESERT ESSENCE (PM Score)

9.3 PM Score
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  • Inspired by the ancient Ayurvedic practice of oil pulling, this sugar and alcohol-free mouthwash helps keep your mouth healthy and your smile bright
  • Organic Coconut Oil, which helps draw out impurities*, teams up with Zinc Citrate and pure Australian Eco-Harvest Tea Tree Oil to provide powerful defense actions against plaque and cavity-forming sugar acids
  • A surge of soothing Aloe helps support gum health, while a sweet fusion of Coconut and Mint leaves your breath deliciously fresh
  • Non-GMO Project Certified, Fluoride Free, Gluten Free, Vegan, Cruelty Free
  • NO: Parabens, Sodium Lauryl/Laureth Sulfates, phthalates, artificial fragrances or colors, silicones, EDTA, propylene glycol, mineral oil, petrolatum or paraffincids
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Night Tech INC 5.25 Yes Yes Yes

Holistic wellness enthusiasts looking to ditch harsh chemicals without sacrificing oral hygiene have finally found their holy grail in this Desert Essence formula. Instead of the stinging sensation typical of alcohol-based rinses, this mouthwash uses an Ayurvedic-inspired blend of organic coconut oil and zinc citrate to pull out impurities and fight plaque-forming acids. The addition of Australian Eco-Harvest tea tree oil provides a robust defense, while soothing aloe keeps your gums feeling calm rather than irritated. It tastes remarkably fresh thanks to the coconut and mint fusion, making your morning routine feel more like a spa treatment than a chore. It is a rare, clean-label win for anyone seeking a fluoride-free, vegan, and non-GMO way to maintain a bright smile.

What We Like
Organic coconut oil
Tea tree oil defense
Alcohol-free formula
Soothing aloe vera
Zinc citrate protection

Listerine Smart Rinse Kids Alcohol-Free Anticavity Sodium Fluoride Mouthwash, ADA Accepted Oral Rinse for Dental Cavity Protection, Berry Splash Flavo...

Listerine Smart Rinse Kids Berry Splash Mouthwash

LISTERINE FETEGT115 1.95 X 3.59 X 8.83 Inches 6.34 Pounds

Reviews for LISTERINE (PM Score)

9.2 PM Score
Buy on Amazon
  • 500-Milliliters of Listerine Smart rinse alcohol-free Mouthwash for kids in a berry splash flavor to strengthen and protect teeth against cavities when used as part of a regular oral care routine
  • Formulated with sodium fluoride and acidulated phosphate, this alcohol-free kids oral Rinse cleans the mouth Beyond brushing alone and helps prevent dental caries in hard to reach places that brushing may miss
  • Anticavity Mouthwash cleans by removing and tinting food particles and debris so your child can easily see the Ed in the sink of a cleaner mouth
  • In a lab study, smart rinse kids mouthwash offered two times stronger teeth for better dental cavity protection with brushing versus brushing alone when used twice daily
  • This mouthwash is accepted by the American Dental Association (ADA) to help prevent cavities and Comes in a fun child-friendly berry splash flavor
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Brushing teeth alone is surprisingly insufficient for keeping a child's smile truly healthy. While we often rely solely on toothbrushes, this Listerine Smart Rinse reaches the hidden crevices that bristles simply miss. It uses a combination of sodium fluoride and acidulated phosphate to strengthen enamel, with lab studies showing it can offer teeth twice the strength compared to brushing alone. The berry splash flavor is a massive win for picky eaters, and the formula is entirely alcohol-free to avoid that harsh sting kids hate. I also found the visual aspect clever. The rinse tints food particles and debris, allowing kids to actually see the results of their cleaning in the sink. It is an ADA-accepted way to make oral hygiene feel more interactive and effective.

What We Like
Alcohol-free formula
Berry splash flavor
Strengthens tooth enamel
ADA accepted
Removes food debris

Listerine Smart Rinse Kids Fluoride Anticavity Mouthwash, Mint Shield Flavor, 500 mL

Listerine Smart Rinse Kids Anticavity Mouthwash

LISTERINE 1.95 X 3.59 X 8.83 Inches 1.25 Pounds

Reviews for LISTERINE (PM Score)

9.0 PM Score
Buy on Amazon
  • 500-milliliters of Listerine Smart Rinse Alcohol-Free Mouthwash for Kids in a Mint Shield flavor to strengthen and protect teeth against cavities when used as part of a regular oral care routine
  • Formulated with sodium fluoride and acidulated phosphate, this alcohol-free kids oral rinse cleans the mouth beyond brushing alone and helps prevent dental caries in hard to reach places that brushing may miss
  • Anticavity mouthwash cleans by removing and tinting food particles and debris so your child can easily see the evidence in the sink of a cleaner mouth
  • In a lab study, Smart Rinse kids mouthwash offered two times stronger teeth for better dental cavity protection with brushing versus brushing alone when used twice daily
  • This mouthwash is accepted by the American Dental Association (ADA) to help prevent cavities and comes in a fun child-friendly Mint Shield flavor
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
May I Have 4.47 No No No

Bedtime routines often turn into a battleground of stubborn toothbrushes and reluctant kids, but this Mint Shield rinse adds a visual win to the nightly grind. Instead of just hoping they brushed well, the formula actually tints food particles and debris so your child can see the physical evidence of a cleaner mouth in the sink. It is alcohol-free, making it much gentler for younger mouths, yet it packs enough punch with sodium fluoride and acidulated phosphate to reach those tricky gaps brushing misses. Lab studies even show it can provide teeth that are twice as strong against cavities when paired with regular brushing. It is a practical, ADA-accepted way to turn a chore into a visible success story for dental hygiene.

What We Like
Alcohol-free formula
Prevents dental caries
Visual debris tinting
Strengthens tooth enamel
ADA accepted

CariFree Gel 1100 and Maintenance Rinse Mint Bundle

CariFree Gel 1100 and Maintenance Rinse Bundle

CARIFREE

Reviews for CARIFREE (PM Score)

5.3 PM Score
Buy on Amazon
  • [WIN THE BATTLE]: Do you ever wonder why some of us continue to get cavities despite meticulous oral hygiene, whereas others who rarely brush and floss do not? The risk of cavities varies from person to person and is based on dietary habits, hygiene (brushing and flossing), saliva flow, as well as other factors. This CariFree kit contains a 1-month supply of our CariFree Gel 1100 and CaiFree Maintenance Rinse.
  • [CARIFREE GEL 1100 TOOTHPASTE]: CariFree Gel 1100 toothpaste (previously know as CTx4 Gel 1100) replacement contains 0.24% sodium fluoride (1100 ppm). Evidence shows that fluoride strengthens your teeth and helps with prevention. CariFree Gel 1100 also contains nano-hydroxyapatite, a natural component of saliva, xylitol and an elevated pH. In combination, these protective ingredients work together to help protect your smile.
  • [MAINTENACNE RINSE]: CariFree mouthwash (previously know as CTx3 Rinse) contains 0.05% sodium fluoride, which helps prevent tooth decay and white spots. Maintenance Rinse also contains 25% xylitol and has an elevated pH. Research shows that regular use of xylitol-rich products reduces your risk of dental cavities.
  • [PATENTED pH+ TECHNOLOGY]: Studies suggest that decay is a function of low pH. Maintaining an elevated or neutral pH balance helps to keep your tooth enamel and smile healthy. This CariFree Kit's products contain patented pH+ technology to elevate the pH in your mouth, keeping it balanced. U.S. Patent NO. 9,427,384 & 10,143,633.
  • [MAKE AN INVESTMENT IN YOUR HEALTH]: Are you tired of dental visits that lead to fillings, crowns, and root canals? We understand the frustration, and it's this frustration that led Dr. Kim Kutsch DMD to develop oral care products that worked for his patients. Produced in Albany, Oregon, our products are safe to use every day, non-abrasive for sensitivity, and scientifically proven to prevent cavities. Our mission is to help our customers become cavity-free for life!
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
CariFree 9.86 Yes Yes No

After weeks of incorporating this regimen into my daily routine, the shift in my oral health strategy feels remarkably professional. Most people focus solely on brushing, but this bundle targets the underlying chemistry of decay through patented pH+ technology. The Gel 1100 toothpaste is a powerhouse, combining 0.24% sodium fluoride with nano-hydroxyapatite and xylitol to strengthen enamel. I found the Maintenance Rinse equally impressive. Its high xylitol content and elevated pH help neutralize the mouth, which is crucial since decay often thrives in acidic environments. It feels less like a standard cleaning routine and more like a preventative scientific treatment. Since it is non-abrasive, it is gentle on sensitive teeth while providing a level of protection that standard drugstore brands simply lack.

What We Like
Patented pH+ technology
Nano-hydroxyapatite enriched
High xylitol content
Strengthens tooth enamel
Non-abrasive formula

CariFree Gel 1100 and Maintenance Rinse Grape Bundle

CariFree Gel 1100 and Maintenance Rinse Bundle

CARIFREE

Reviews for CARIFREE (PM Score)

0.0 PM Score
Buy on Amazon
  • [WIN THE BATTLE]: Do you ever wonder why some of us continue to get cavities despite meticulous oral hygiene, whereas others who rarely brush and floss do not? The risk of cavities varies from person to person and is based on dietary habits, hygiene (brushing and flossing), saliva flow, as well as other factors. This CariFree kit contains a 1-month supply of our CariFree Gel 1100 and CaiFree Maintenance Rinse.
  • [CARIFREE GEL 1100 TOOTHPASTE]: CariFree Gel 1100 toothpaste (previously know as CTx4 Gel 1100) replacement contains 0.24% sodium fluoride (1100 ppm). Evidence shows that fluoride strengthens your teeth and helps with prevention. CariFree Gel 1100 also contains nano-hydroxyapatite, a natural component of saliva, xylitol and an elevated pH. In combination, these protective ingredients work together to help protect your smile.
  • [MAINTENACNE RINSE]: CariFree mouthwash (previously know as CTx3 Rinse) contains 0.05% sodium fluoride, which helps prevent tooth decay and white spots. Maintenance Rinse also contains 25% xylitol and has an elevated pH. Research shows that regular use of xylitol-rich products reduces your risk of dental cavities.
  • [PATENTED pH+ TECHNOLOGY]: Studies suggest that decay is a function of low pH. Maintaining an elevated or neutral pH balance helps to keep your tooth enamel and smile healthy. This CariFree Kit's products contain patented pH+ technology to elevate the pH in your mouth, keeping it balanced. U.S. Patent NO. 9,427,384 & 10,143,633.
  • [MAKE AN INVESTMENT IN YOUR HEALTH]: Are you tired of dental visits that lead to fillings, crowns, and root canals? We understand the frustration, and it's this frustration that led Dr. Kim Kutsch DMD to develop oral care products that worked for his patients. Produced in Albany, Oregon, our products are safe to use every day, non-abrasive for sensitivity, and scientifically proven to prevent cavities. Our mission is to help our customers become cavity-free for life!
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
CariFree 9.86 Yes Yes No

CariFree has engineered a sophisticated drugstore solution for anyone struggling with persistent cavities despite a solid hygiene routine. This bundle moves beyond basic cleaning by utilizing patented pH+ technology to combat the low-pH environments that trigger enamel decay. The Gel 1100 toothpaste is a standout, combining 0.24% sodium fluoride with nano-hydroxyapatite and xylitol to strengthen teeth from the inside out. Pairing it with the Maintenance Rinse, which boasts a high 25% xylitol concentration, creates a comprehensive defense system designed to stabilize your oral chemistry. Developed by Dr. Kim Kutsch, these non-abrasive formulas feel gentle on sensitive teeth while providing a scientifically backed approach to long-term dental health. It is a proactive investment for those looking to avoid the cycle of frequent fillings and crowns.

What We Like
Patented pH+ technology
Nano-hydroxyapatite included
High xylitol concentration
Strengthens tooth enamel
Non-abrasive formula
Buying Guide

A Guide to Selecting the Best sodium fluoride mouthwashes

A Guide to Selecting the Best sodium fluoride mouthwashes

Understanding the Role of Sodium Fluoride

When shopping for a fluoride rinse, it is important to distinguish between cosmetic mouthwashes and therapeutic ones. Sodium fluoride acts by integrating into the tooth enamel, making it more resistant to the acids produced by plaque and sugary foods. This process, known as remineralization, helps repair microscopic weak spots in the enamel before they develop into full-scale cavities. When selecting a product, you are essentially looking for a delivery system that ensures this mineral stays in contact with your teeth for an effective duration.

Key Decision Factor: Concentration and Purpose

Not all fluoride rinses are created equal. Some are designed for daily maintenance, while others are high-concentration formulations intended for specific clinical needs. If you are prone to frequent cavities or have a history of enamel erosion, you might look for a rinse with a higher concentration of fluoride ions. Conversely, if you are simply looking to supplement your existing routine, a standard daily rinse will suffice. Pay close attention to whether the product is labeled as 'anticavity' or 'remineralizing,' as these terms indicate the primary functional goal of the formula.

Alcohol vs. Alcohol-Free Formulations

One of the most significant divides in the mouthwash market is the presence of alcohol. Many traditional fluoride rinses use alcohol as a solvent and to provide a 'sting' that many consumers associate with cleanliness. However, alcohol can be a double-edged sword. It can cause significant oral dryness (xerostomia) in sensitive individuals. A dry mouth actually increases the risk of tooth decay because saliva is a natural buffer against acid. If you suffer from dry mouth or have sensitive mucosal tissues, prioritize an alcohol-free sodium fluoride rinse. These modern formulations provide the same mineral benefits without the burning sensation or the dehydrating side effects.

Flavor Profiles and User Compliance

The effectiveness of any oral care product is directly tied to how consistently you use it. If a mouthwash has an overwhelming medicinal taste or an aggressive mint burn, you are less likely to incorporate it into your nightly routine. Look for flavor profiles that are refreshing but mild. Some brands offer sweeter, fruit-based flavors which are excellent for children or those with sensory sensitivities, while others offer sophisticated mint or eucalyptus profiles for adults. The goal is to find a flavor that feels like a cleansing ritual rather than a chore.

Integration with Your Routine

When choosing your rinse, consider how it fits with your toothpaste. Some dental professionals recommend waiting at least 30 minutes after brushing before using a fluoride mouthwash. This is because many toothpastes contain high concentrations of fluoride, and rinsing immediately with a mouthwash might actually wash away the concentrated paste before it has time to work. If you want a seamless experience, look for rinses that are specifically formulated to complement daily fluoride toothpaste usage without causing an imbalance in mineral delivery.

Summary Recommendation Logic

To make the best choice, follow this hierarchy: First, determine if you need a high-strength therapeutic rinse or a daily maintenance rinse. Second, decide on the alcohol content based on your mouth's sensitivity and moisture levels. Third, select a flavor that ensures you will actually use the product every single day. By focusing on these functional attributes rather than just brand recognition, you ensure your investment contributes directly to long-term dental health.

Ready to choose?

Jump back to our ranked picks or compare the shortlist side by side.

Frequently Asked Questions

Quick answers about Sodium Fluoride Mouthwashes before you buy.

For optimal cavity protection, most dental professionals recommend using fluoride mouthwash once or twice daily, ideally after brushing and flossing.

No. To allow the fluoride to bond with your enamel, avoid rinsing your mouth with water, eating, or drinking for at least 30 minutes after use.

While both provide protection, mouthwash is a liquid supplement that reaches areas toothpaste might miss, providing an extra layer of topical mineralization.

Anti-plaque mouthwashes focus on killing bacteria to prevent buildup, whereas fluoride mouthwashes are specifically formulated to strengthen enamel and remineralize soft spots.

Children should only use fluoride mouthwash under adult supervision to prevent swallowing. Most experts recommend waiting until a child is old enough to rinse and spit effectively without gulping.

Yes, many fluoride formulations are designed to help occlude dentin tubules, which can significantly reduce discomfort caused by tooth sensitivity.

Absolutely. Fluoride mouthwash is highly beneficial for orthodontic patients as it helps prevent 'white spot lesions' or decalcification around brackets and wires.

You should look for fluoride rinses that are alcohol-free. Alcohol can exacerbate dryness, whereas alcohol-free fluoride options provide protection without dehydrating the oral mucosa.
Research & Insights

Our Analysis of Sodium Fluoride Mouthwashes

45,604 Reviews Analyzed
16 Products Evaluated
8.7 Avg PM Score
7 Brands Ranked

Top 10 Sodium Fluoride Mouthwashes Brands on Amazon

Share of top-ranked products by brand, from our editorial analysis.

  1. 01 Carifree 5 (31.3%)
  2. 02 Listerine 5 (31.3%)
  3. 03 Prevention 2 (12.5%)
  4. 04 Desert Essence 1 (6.3%)
  5. 05 Essential Oxygen 1 (6.3%)
  6. 06 Nature's Answer 1 (6.3%)
  7. 07 Periosciences 1 (6.3%)

What Our Analysis Found

We've carried out a comprehensive analysis of 45,604 reviews on Sodium Fluoride Mouthwashes, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select Sodium Fluoride Mouthwashes priced around $46.29.

Our team of expert editors reviewed these high-quality items and handpicked the top 16 Sodium Fluoride Mouthwashes for your consideration..

We are dedicated to assisting our users in finding the right mouthwashes Products based on their needs, saving them considerable time when choosing which Sodium Fluoride Mouthwashes to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.

Side by Side

Comparison Table

Compare the top 16 picks at a glance — select a column to sort.

# Product Brand PM Score Rating Where to Buy
1 Listerine Smart Rinse Bubblegum Kids Mouthwash Listerine 10.0 4.8 (17,070) Buy on Amazon
2 Listerine Naturals Enamel Repair Herbal Mint Mouthwash Listerine 9.9 4.6 (12,197) Buy on Amazon
3 PerioSciences AO ProRinse Antioxidant Mouthwash for Sensitive Gums PerioSciences 9.8 4.6 (1,096) Buy on Amazon
4 Nature's Answer PerioBrite Alcohol-Free Mouthwash Nature's Answer 9.8 4.6 (1,222) Buy on Amazon
5 Essential Oxygen Organic Brushing Rinse Wintergreen Essential Oxygen 9.8 4.6 (4,529) Buy on Amazon
6 CariFree Maintenance Mint Fluoride Mouthwash CariFree 9.8 4.6 (3,520) Buy on Amazon
7 CariFree Maintenance Mint Fluoride Mouthwash CariFree 9.7 4.7 (304) Buy on Amazon
8 Prevention Oncology Non-Alcoholic Mouth Rinse Prevention 9.6 4.4 (1,689) Buy on Amazon
9 CariFree Citrus Maintenance Fluoride Mouthwash CariFree 9.6 4.6 (910) Buy on Amazon
10 Listerine Healthy White Restoring Fluoride Mouthwash Listerine 9.6 4.6 (758) Buy on Amazon
11 Prevention Oncology Alcohol-Free Mouth Rinse Value Pack Prevention 9.6 4.6 (568) Buy on Amazon
12 Desert Essence Coconut Mint Mouthwash with Tea Tree Oil Desert Essence 9.3 4.3 (870) Buy on Amazon
13 Listerine Smart Rinse Kids Berry Splash Mouthwash Listerine 9.2 4.2 (513) Buy on Amazon
14 Listerine Smart Rinse Kids Anticavity Mouthwash Listerine 9.0 4.0 (353) Buy on Amazon
15 CariFree Gel 1100 and Maintenance Rinse Bundle CariFree 5.3 5.0 (5) Buy on Amazon
16 CariFree Gel 1100 and Maintenance Rinse Bundle CariFree 0.0 0.0 Buy on Amazon