Best Naproxen Sodium in 2026

Daisy
Last Updated: Jan 22, 2026

At a Glance: Our Top Picks for Naproxen Sodium

Amazon Basic Care Naproxen Sodium Tablets, 200 Count (Pack of 1)
#TOP1
Amazon Basic Care Naproxen Sodium Tablets, 200 Count
9.9
PM SCORE
Amazon Basic Care Back and Muscle Pain, Naproxen Sodium Tablets 220 mg, Pain Reliever and Fever Reducer, For Backache, Muscular Aches, Minor Arthritis Pain, Headache and More, 90 Count
#TOP2
Amazon Basic Care Back And Muscle Pain, Naproxen
9.8
PM SCORE
Aleve Easy Open Arthritis Cap Tablets, Naproxen Sodium for Pain Relief ‐ 200 Count
#TOP3
Aleve Easy Open Arthritis Cap Tablets, Naproxen Sodium
9.8
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Naproxen Sodium of 2026

Market Overview
Naproxen Sodium Reviewed
  • Reviews Analyzed: 7252 Items
  • PM Avg. Rating: 5.9 / 10
19 Products Evaluated
  • Highest Price: $79.95
  • Lowest Price: $6.43
  • Avg. Price: $28.29
#TOP1

Amazon Basic Care Naproxen Sodium Tablets, 200 Count (Pack Of 1)

AMAZON BASIC CARE
1
2.00 X 4.25 X 2.03 Inches
0.22 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: This pain reliever and fever reducer contains naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID); compare to the active ingredient in Aleve Caplets

STRENGTH TO LAST 12 HOURS: Pain reliever and fever reduction for up to 12 hours so you can get through the day

ACHES AND PAINS: Temporarily relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold; also temporarily reduces fever

ALL DAY RELIEF: Amazon Basic Care Naproxen Sodium Tablets 220 mg is a pain reliever and fever reducer for adults and children age 12 years and over

CAPSULE-SHAPED TABLETS: This 12 hour pain reliever and fever reducer comes in a capsule-shaped tablet; this product is gluten free

Amazon Basic Care Back And Muscle Pain, Naproxen Sodium Tablets 220 Mg, Pain Reliever And Fever Reducer, For Backache, Muscular Aches, Minor Arthritis Pain, Headache And More, 90 Count

AMAZON BASIC CARE
1
1.88 X 3.69 X 1.81 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: Amazon Basic Care Back and Muscle Pain contains the active ingredient naproxen sodium 220, a nonsteroidal anti-inflammatory drug (NSAID) and pain reliever/fever reducer. Compare to the active ingredient in Aleve Back and Muscle Pain.

BACK and MUSCLE: Count on up to 12 hours of relief with one dose of Amazon Basic Care Back and Muscle Pain Naproxen Sodium Tablets, 220 mg, a pain reliever and fever reducer for temporary relief of minor back and muscle aches and pains.

MINOR ACHES and PAINS: Amazon Basic Care Back and Muscle Pain Naproxen Sodium Tablets, 220 mg also alleviates: backache, muscular aches, minor pain of arthritis, menstrual cramps, headache, toothache, the common cold and temporarily reduces fever.

12 HOURS: A pain reliever and fever reducer with the strength to last 12 hours means stopping less often to take more doses.

ADULTS and ADOLESCENTS: This product contains naproxen sodium 220 mg, a pain reliever and fever reducer for use in adults and children age 12 years and older.

#TOP3

Aleve Easy Open Arthritis Cap Tablets, Naproxen Sodium For Pain Relief ‐ 200 Count

ALEVE
6.00 X 4.00 X 4.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Best Online Deal5 6.79

Features

UP TO 12-HOUR PAIN RELIEF MEDICINE: Minor arthritis, headache, and back pain relief medicine, with the strength to last up to 12 hours

FEVER REDUCER: This pain medicine for adults and children ages 12 and up also temporarily reduces fever

EFFECTIVE PAIN RELIEVER: Temporarily reduces fever and relieves minor pain of arthritis, menstrual cramps, muscular aches, backache, toothache, headache and the common cold

EASY OPEN ARTHRITIS CAP: This medication comes in a contoured bottle that fits comfortably in your hand, with an easy open cap. Not child resistant.

DOCTOR RECOMMENDED: Aleve is the #1 orthopedic surgeon recommended OTC brand for minor arthritic pain.

#TOP4

Aleve Liquid Gels With Easy Open Arthritis Cap, Naproxen Sodium Capsules 220 Mg (Nsaid), Pain Reliever/Fever Reducer, Fast Pain Relief, 80 Count

ALEVE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
GOLDEN WAREHOUSE 6.22

Features

Aleve is the #1 Orthopedic Surgeon Recommended over-the-counter brand for minor arthritis pain.

Only Aleve Works at the Site of Pain All Day with Just Two Pills. Aleve is different, unlike Tylenol and Advil, each Aleve caplet has the strength to last 12 hours.**

Get Fast, Continuous Pain Relief with Aleve Liquid Gels.

The Aleve Easy Open Cap features a contoured bottle that fits comfortably in your hand and a cushioned cap to give you better control. Easy Open cap is not child resistant.

Aleve is an over-the-counter (OTC), nonsteroidal anti-inflammatory drug (NSAID) that has provided temporary relief from minor aches and pains for 25 years.

Aleve provides temporary relief of minor aches and pains due to backaches, muscular aches, headaches, minor arthritis and other joint pain, menstrual pain, toothaches, and the common cold. Also temporarily reduces fever. *Data on file. **Based on minimum labeled dosing.

#TOP5

Aleve Soft Grip Arthritis Cap Gelcaps, Naproxen Sodium 220 Mg (Nsaid), Pain Reliever/Fever Reducer, #1 Orthopedic Surgeon Recommended, 40 Count

ALEVE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
YSSG Deals 9.76

Features

Aleve is the #1 Orthopedic Surgeon Recommended over-the-counter brand for minor arthritis pain.

Only Aleve Works at the Site of Pain All Day with Just Two Pills. Aleve is different, unlike Tylenol and Advil, each Aleve caplet has the strength to last 12 hours.**

The Aleve Soft Grip Arthritis Cap features a contoured bottle that fits comfortably in your hand and a cushioned cap to give you better control. Soft Grip cap is child resistant.

Aleve is an over-the-counter (OTC), nonsteroidal anti-inflammatory drug (NSAID) designed to deliver continuous pain relief at the site of pain.

For 25 years, Aleve has provided temporary relief of minor aches and pains due to backaches, muscular aches, headaches, minor arthritis and other joint pain, menstrual pain, toothaches, and the common cold. Also temporarily reduces fever.

**Based on minimum labeled dosing.

#TOP6

Aleve Pm, 80 Count

ALEVE
BY-297
1.44 X 4.75 X 2.00 Inches
0.15 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Generic Giant 9.44

Features

Two Aleve PM caplets help you fall asleep for a good night’s rest and wake up with less pain

Also available with Easy Open and Soft Grip Caps

For occasional sleeplessness associated with minor aches and pains

ALEVE is proven better on tough pain than Tylenol 8hr. *Based on menstrual and dental pain studies.

For minor aches and pains due to minor arthritis, back and body aches, and headache

#TOP7

Aleve Soft Grip Arthritis Cap Caplets With Naproxen Sodium, 220Mg (Nsaid) Pain Reliever/Fever Reducer, 270 Count

ALEVE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
DeRomo 9.92

Features

The Aleve Soft Grip Arthritis Cap has received the Arthritis Foundation's Ease of Use Commendation

Just 1 caplet can manage pain for up to 12 hours

The Soft Grip Arthritis Cap is child resistant

ALEVE is proven better on tough pain than Tylenol 8hr. *Based on menstrual and dental pain studies.

ALEVE is the #1 recommended brand for minor arthritis pain among orthopedic doctors.

Member's Mark 220 Mg Naproxen Sodium (400 Ct.) By Members Mark

MEMBERS MARK
078742091433-1-A4
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Lowest_Price_Highest_Quality_Fastest_Shipping 8.90

Features

Compare to the active ingredient in Aleve

Pain reliever

Fever reducer

Strength to last 12 hours

#TOP9

Aleve Pain Reliever/Fever Reducer Tablets, 220 Mg 10 Ea (Pack Of 2)

ALEVE
935
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Pattern Products 9.95

Features

Up to 12-hour pain relief medicine: Minor arthritis, headache, and back pain relief medicine, with the strength to last up to 12 hours

Fever reducer: This pain medicine for adults and children ages 12 and up also temporarily reduces fever

Effective pain reliever: Temporarily reduces fever and relieves minor pain of arthritis, menstrual cramps, muscular aches, backache, toothache, headache and the common cold

Child-resistant packaging: Aleve pain relief pills come in a convenient, child‐resistant bottle

Doctor recommended: Aleve is the #1 orthopedic surgeon recommended OTC brand for minor arthritic pain

Aleve Liquid Gels Easy Open Arthritis Cap 80 Liquid Gels (Pack Of 3)

ALEVE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
PharmacyStoreStruff 9.65

Features

LONG LASTING RELIEF: Each Aleve liquid gel has the strength to last up to 12 hours""LONG LASTING RELIEF: Each Aleve liquid gel has the strength to last up to 12 hours

FEVER REDUCER: This pain medicine for adults and children ages 12 and up also temporarily reduces fever

EFFECTIVE PAIN RELIEVER: Temporarily reduces fever and relieves minor pain of arthritis, muscular aches, backache, toothache, menstrual cramps, headache and the common cold

EASY OPEN ARTHRITIS CAP: This comes in a contoured bottle that fits comfortably in your hand, with an easy open cap. Not child resistant

DOCTOR RECOMMENDED: Aleve pain relief pills are the #1 orthopedic surgeon recommended oral OTC brand for minor arthritic pain

EASY TO TAKE: This Aleve Naproxen Sodium 220 mg pain medicine comes in liquid gel form that makes it easy to swallow

Medique @ Home Mediproxen Compare Active Ingredient To Aleve 50 X 1 (Child Resistant Packaging), White (73750)

MEDIQUE
73750
4.13 X 3.00 X 3.75 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Medique @ Home the brands that work now work at home

Each tablet contains Naproxen Sodium 220mg

Compares to Aleve

Long lasting relief from pain associated with headaches, muscular aches and minor arthritis

Effectively reduces fevers from colds and flu

#TOP12

Welly Remedies | Otc 12-Hour Pain Reliever | Pain Relief/Fever Reducer | Naproxen Sodium | Medicine With Proven Active Ingredients

WELLY
1.88 X 1.88 X 3.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
gilded leaf 7.68

Features

Naproxen Sodium 220 mg pain relief

Made with the same active ingredient as the leading brands

Free from artificial flavors, dyes, parabens and talc

Temporarily relieves minor aches and pains due to: minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache, the common cold; Temporarily reduces fever

40 softgels

Naproxen sodium 220 mg (naproxen 200 mg) (NSAID)* *nonsteroidal anti-inflammatory drug

Aleve Pm Soft Grip 3Dz 120 Ct (Pack Of 2)

ALEVE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Generic Giant 9.43

Features

LONG LASTING RELIEF: Two Aleve PM caplets help you fall asleep for a good night's rest and wake up refreshed and relieved from pain

NIGHTTIME ALEVE PAIN RELIEVER: Pain relief caplets indicated for occasional sleeplessness associated with minor aches and pains

EFFECTIVE OVER‐THE‐COUNTER PM PRODUCT: Only Aleve PM combines a sleep aid and the 12‐hour pain relieving strength of Aleve

Soft Grip Cap: This medication comes in a contoured bottle that fits comfortably in your hand, with a Soft Grip Cap that is covered with a cushioned material

ALL NIGHT RELIEF: Two caplets can help you fall asleep and stay asleep to wake up refreshed and relieved from pain

EASY TO TAKE: Aleve PM comes in small, oval caplets that are easy to swallow

Aleve Cplt 2Dz 200 Ct (Pack Of 3)

ALEVE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
ISKOLIVE 12 INC 9.86

Features

UP TO 12-HOUR PAIN RELIEF MEDICINE: Minor arthritis, headache, and back pain relief medicine, with the strength to last up to 12 hours

FEVER REDUCER: This pain medicine for adults and children ages 12 and up also temporarily reduces fever

EFFECTIVE PAIN RELIEVER: Temporarily reduces fever and relieves minor pain of arthritis, menstrual cramps, muscular aches, backache, toothache, headache and the common cold

EASY OPEN ARTHRITIS CAP: This medication comes in a contoured bottle that fits comfortably in your hand, with an easy open cap. Not child resistant.

DOCTOR RECOMMENDED: Aleve is the #1 orthopedic surgeon recommended oral OTC brand for minor arthritic pain.

EASY TO TAKE: Aleve Naproxen Tablets comes in small, round form that makes them easy to swallow

Good Sense Naproxen Sodium Tablets 220 Mg And Goodsense Arthritis Pain Relieving Gel, Diclofenac Sodium Topical Gel, 1 Percent

GOODSENSE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

CONVENIENCE PACK: Products are not intended to be taken together; use each product only as directed

NAPROXEN SODIUM: GoodSense Naproxen Sodium Tablets 220 mg are a nonsteroidal anti-inflammatory drug (NSAID); compare to the active ingredient of Aleve Caplets

ARTHRITIS PAIN RELIEF: GoodSense Arthritis Pain Relieving Gel contains diclofenac sodium, an NSAID (non-steroidal anti-inflammatory drug) 1 percent (equivalent to 0.93 percent diclofenac); compare to the active ingredient in Voltaren Arthritis Pain

JOINT PAIN RELIEF: GoodSense Arthritis Pain Relieving Gel is an arthritis pain reliever for hands, wrists, elbows, feet, ankles and knees

STRENGTH TO LAST 12 HOURS: GoodSense Naproxen Sodium Tablets 220 mg relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold; temporarily reduces fever

#TOP16

Aleve Pain Reliever/Fever Reducer Tablets, 220 Mg 10 Ea (Pack Of 3)

ALEVE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Pattern Products 9.95

Features

UP TO 12-HOUR PAIN RELIEF MEDICINE: Minor arthritis, headache, and back pain relief medicine, with the strength to last up to 12 hours

FEVER REDUCER: This pain medicine for adults and children ages 12 and up also temporarily reduces fever

EFFECTIVE PAIN RELIEVER: Temporarily reduces fever and relieves minor pain of arthritis, menstrual cramps, muscular aches, backache, toothache, headache and the common cold

CHILD‐RESISTANT PACKAGING: Aleve pain relief pills come in a convenient, child‐resistant bottle

DOCTOR RECOMMENDED: Aleve is the #1 orthopedic surgeon recommended oral OTC brand for minor arthritic pain.

EASY TO TAKE: Aleve Naproxen Tablets comes in small, round form that makes them easy to swallow

Naproxen Sodium 220 Mg 500Ct

CAMBER
69230032905
2.50 X 2.50 X 4.80 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Camber 5.81

Features

12 Hour Pain relief Medicine: headache, Bodyache, tooth ache relief for 12 hours

Effective Pain reliever for menstrual cramps,minor arthiritis and muscle pains

Temporary Fever Reducer

#TOP18

A+Health Naproxen Sodium 220 Mg Liquid Gels, Pain Reliever/Fever Reducer (Nsaid), Made In Usa, 180 Count

A+HEALTH
NAP180
2.75 X 2.75 X 4.84 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT NAPROXEN SODIUM: Contains active ingredient Naproxen 220mg (nonsteroidal anti-inflammatory drug) in an easy-to-swallow capsule—compare to the active ingredient in Aleve Liquid Gels

TEMPORARY PAIN RELIEF: Temporarily reduces fever and relieves minor pains due to headaches, toothaches, backaches, menstrual cramps, the common cold, muscular aches, and minor arthritis pain

LIQUID-FILLED CAPSULES: Our A+ Health Naproxen Sodium capsules are liquid-filled capsules which can provide rapid relief and get you back on track

12 HOUR RELIEF: Proudly made in the USA using ingredients originating from various countries for 12 hour relief from most common aches and pains at a great value; Contains 180 capsules

FAST-ACTING: Don’t let pain get in your way! Find fast-acting relief on-the-go with these easy-to-swallow capsules so you can get back to living

#TOP19

Aleve, Caplets, Box Of 50 (50/1'S)

PM MEDICAL
64754
0.21 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Aleve, Caplets, Box of 50 (50/1's) PAIN RELIEF

PAIN RELIEF

Top 10 naproxen sodium Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Aleve 10
Amazon Basic Care 2
A+Health 1
Camber 1
Goodsense 1
Medique 1
Members Mark 1
Pm Medical 1
Welly 1

Top 10 naproxen sodium Brands Pie Chart


We've carried out a comprehensive analysis of 7,252 reviews on naproxen sodium, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select naproxen sodium priced around $28.29, with top brands including good sense, camber, goodsense, members mark, medique, aleve, pamprin and pm medical and flanax

Our team of expert editors reviewed these high-quality items and handpicked the top 19 naproxen sodium for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, camber, lowest_price_highest_quality_fastest_shipping, iskolive 12 inc and highly rated choice and generic giant .

We are dedicated to assisting our users in finding the right sodium Products based on their needs, saving them considerable time when choosing which naproxen sodium to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.