Best Gluten Free P5P Dietary Supplements in 2026

Daisy
Last Updated: Aug 2, 2026

At a Glance: Our Top Picks for Gluten Free P5P Dietary Supplements

Nature’s Bounty Super B Complex with Vitamin C & Folic Acid, Immune & Energy Support, 150 tablets
#TOP1
Nature’s Bounty Super B Complex With Vitamin C
9.9
PM SCORE
Super B-Complex – Methylated Sustained Release B Complex & Vitamin C, Folate & Methylcobalamin, Vegan, Energy, Heart & Brain Function, 60 Small Tablets
#TOP2
Super B-Complex – Methylated Sustained Release B Complex
9.9
PM SCORE
Jarrow Formulas Ultra Strength Methyl B-12 &Methyl Folate - 60 Chewable Tablets, Cherry Flavored - Bioactive Vitamin B12 & B9 - Cellular Energy and Cardiovascular Support (PACKAGING MAY VARY)
#TOP3
Jarrow Formulas Ultra Strength Methyl B-12 &Methyl Folate
9.8
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Gluten Free P5P Dietary Supplements of 2026

Nature’s Bounty Super B Complex With Vitamin C & Folic Acid, Immune & Energy Support, 150 Tablets

NATURE'S BOUNTY
74312131684
1.98 X 1.98 X 4.17 Inches
0.17 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

FOR ENERGY: 150-count Coated Tablets; Nature’s Bounty Super B-Complex with Folic Acid Plus Vitamin C plays an important role in energy metabolism in the body(1); Helps the body convert food into the fuel which is used to maintain energy(1)

VITAMIN B: Contains key B vitamins that play an important role in energy metabolism; B vitamins may help with heart and nervous system health and aids in the conversion of food into energy(1)

VITAMIN C & FOLIC ACID: Nature’s Bounty Super B-Complex is a great way to increase your intake of these important vitamins for immune and antioxidant support while Folic Acid may help with energy metabolism and promotes the health of pregnant women(1)

PURITY IS OUR PRIORITY: Nature’s Bounty is committed to safety and purity in all our supplements; Our Super B-Complex is vegetarian-friendly non-GMO gluten-free sugar-free and contains no artificial colors sweeteners or flavors

FROM THE TRUSTED WELLNESS EXPERTS: Nature’s Bounty Super B-Complex tablets are a product of nearly 50 years of dedication to quality consistency and scientific research to make vitamins and nutritional supplements of unrivaled excellence

Super B-Complex – Methylated Sustained Release B Complex & Vitamin C, Folate & Methylcobalamin, Vegan, Energy, Heart & Brain Function, 60 Small Tablets

IGENNUS HEALTHCARE NUTRITION
169
1.85 X 1.85 X 3.43 Inches
0.04 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Igennus 9.87

Features

HIGH STRENGTH, SUPER ABSORBABLE B complex vitamins including thiamine (B1), Riboflavin-5-phosphate (B2), Niacinamide (flush free Niacin - B3), Calcium D-pantothenate (B5), D-Biotin (B7) & Pyridoxal-5-Phosphate (Vit B6)

METHYLATED VITAMIN FORMS that the body utilises immediately: bioavailable folate as methylfolate & methylcobalamin (Vit B12) - no poorly absorbed cyanocobalamin

SUSTAINED RELEASE provides all-day nutrient coverage and twice daily dosing optimises B12 levels

INTENSIVE HEALTH SUPPORT for energy metabolism, the immune and hormonal systems, homocysteine regulation, nutrient metabolism, heart function, psychological function

GMP MANUFACTURED IN THE USA. Vegetarian & Vegan. MTHFR friendly (no synthetic folic acid). Small tablets (9mm)

Jarrow Formulas Ultra Strength Methyl B-12 &Methyl Folate - 60 Chewable Tablets, Cherry Flavored - Bioactive Vitamin B12 & B9 - Cellular Energy And Cardiovascular Support (Packaging May Vary)

JARROW FORMULAS
BMF58
1.88 X 1.88 X 3.50 Inches
0.10 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Bioactive B Vitamins - Methyl B-12 & Methyl Folate provides methylcobalamin (methyl B-12) & methyl folate, which are the biologically active forms of vitamin B12 and B9, plus pyridoxal-5-phosphate (P5P), the coenzyme form of vitamin B6.

Energy Support Benefits - This Jarrow Formulas supplement helps to support cellular energy metabolism production, brain function, DNA & neurotransmitter synthesis, and amino acid metabolism.

Homocysteine Metabolism - The unique combination of these B vitamins support the recycling of homocysteine to methionine to support cardiovascular health.

Convenient Chewable Tablet - Each cherry-flavored chewable tablet delivers 2.5 mg of vitamin B6, 800 mcg of methyl folate, and 5000 mcg of vitamin B12. Contains no wheat, gluten, soybeans, dairy, egg, fish/shellfish, or peanuts/tree nuts.

Superior Science, Smarter Formulas - Informed by strong scientific research, Jarrow Formulas products are carefully crafted to ensure you get the benefit of each and every vitamin, mineral and supplement.

Jarrow Formulas Extra Strength Methyl B-12 & Methyl Folate - 100 Chewable Tablets, Lemon Flavored - Bioactive Vitamin B12 & B9 - Cellular Energy And Cardiovascular Support (Packaging May Vary)

JARROW FORMULAS
BMF14
3.50 X 1.88 X 1.88 Inches
0.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Bioactive B Vitamins - Methyl B-12 & Methyl Folate provides methylcobalamin (methyl B-12) & methyl folate, which are the biologically active forms of vitamin B12 and B9, plus pyridoxal-5-phosphate (P5P), the coenzyme form of vitamin B6.

Energy Support Benefits - This Jarrow Formulas supplement helps to support cellular energy metabolism & neurotransmitter synthesis.

Homocysteine Metabolism - The unique combination of these B vitamins support the recycling of homocysteine to methionine to support cardiovascular health.

Convenient Chewable Tablet - Each lemon-flavored chewable tablet delivers 1.5 mg of vitamin B6, 400 mcg of methyl folate, and 1000 mcg of vitamin B12. Contains no wheat, gluten, soybeans, dairy, egg, fish/shellfish, or peanuts/tree nuts, or sesame.

Superior Science, Smarter Formulas - Informed by strong scientific research, Jarrow Formulas products are carefully crafted to ensure you get the benefit of each and every vitamin, mineral and supplement.

Ez Melts B-Complex With Methylcobalamin And Methylfolate, Sublingual Vitamins, Vegan, Zero Sugar, Natural Strawberry Flavor, 60 Fast Dissolve Tablets

EZ MELTS
019962220357
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
EZ Melts 9.80

Features

DAILY ENERGY - Our natural blend of B vitamins supports increased energy, stamina, focus, and mental clarity throughout the day. Helps promote energy without the afternoon crashes or caffeine jitters.

GREAT TASTING, FAST MELT TABLETS - Natural strawberry flavor combined with our fast-melting technology produces a pleasant, easy to take tablet that melts in your mouth. Competing b complex vitamins are hard to swallow with an awful taste and scent.

SUPPORTS HEART HEALTH - EZ Melts B-Complex supplement includes 100% daily value or more for all B-Vitamins to promote a healthy heart. Including biotin to support the body’s hair, skin, & nail growth.

WELL-BEING - Our unique blend of high quality ingredients are essential for mood support, balance and general feelings of well-being.

MADE IN AMERICA AND QUALITY TESTED - All EZ Melts vitamins are manufactured in sunny Florida with domestic and globally sourced ingredients. Every ingredient is tested by independent 3rd Party Labs located in the USA, ensuring purity and safety.

Nature Made Vitamin B6 100 Mg, Dietary Supplement For Energy Metabolism Support, 100 Tablets, 100 Day Supply

NATURE MADE
1285
2.00 X 2.00 X 4.25 Inches
0.13 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Energy metabolism support supplement: contains one 100 count bottle of Nature Made Vitamin B6 100 mg Tablets for a 100-day supply(1)

This B6 vitamin supplement supports the production of neurotransmitters needed for mood health, and is important for proper red blood cell formation

Nature Made B6 100 mg tablets also help support energy metabolism(1) and nervous system function

Adults take one Nature Made Vitamin B6 100mg tablet daily with water and a meal

This gluten free Vitamin B6 supplement has no color added, no artificial flavors and no preservatives

United States Pharmacopeia (USP) Verified, Number 1 Pharmacist Recommended Vitamin & Supplement Brand*

These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease

Ez Melts Vitamin B6 Supplement To Support Cardiovascular & Nervous System Health - Dissolvable Vegan B6 Vitamins - B 6 Vitamins That Promote Healthy Energy Levels - Fast Dissolving Vitamin B-6

EZ MELTS
EZMELTS016
3.82 X 1.93 X 1.89 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
EZ Melts 9.79

Features

Support Vital Systems –– Don't rely on diet alone. Give your body a helping hand with these vitamin B6 50mg tablets. Helping to support your heart and nervous system health is among the key benefits of taking vit B6 supplements*

Convert Food to Fuel –– Get the most from everything you eat. This B6 vitamin can help support a healthy metabolic function and healthy energy levels.* Vitamin B 6 also supports mood balance to help keep your mind free of clutter.*

No Sweat Supplements –– Gone are the days of chalky tablets you can't choke down. These B6 dissolvable supplements make it easier to get your vitamins. Enjoy vitamins B6 tablets with a refreshing orange flavor that have zero sugar

A Dose for Any Diet –– Take a B6 vitamins 50mg tablet that you can trust. All EZ Melts supplements are made with non-GMO, vegan-friendly ingredients. Each tablet is formulated without the use of common allergens: gluten, dairy, lactose, eggs, nuts, fish, shellfish, and soy.

Manufactured in the USA –– A supplement you can count on. These vitamin B6 50 mg tablets are made at our Florida facilities using ingredients that are globally sourced by our certified US-based suppliers

Kal B-6, B-12, Folic Acid Activmelt | Healthy Heart & Energy Support | Natural Berry Flavor | 60 Micro Tablets, 60 Serv.

KAL
65185
1.89 X 1.89 X 3.66 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Healthway Shop 9.90

Features

Superior B: Formulated for high absorption, 1 micro tablet provides vitamins B-6, B-12 & folic acid

Strong Synergy: Helps support red blood cell synthesis & normal homocysteine levels for heart health

Preferred Form: Our formula contains vitamins B6 & B12 in their active forms, P-5-P & Methyl

ActivMelt: Instantly dissolving micro tablets deliver vitamins w/ a delicious natural berry flavor

Committed to Quality: Lab verified using the strictest standard to ensure purity, identity & potency

P5P Activated Vitamin B6 100Mg | 120 Tablets | Vegetarian Supplement, Non-Gmo, Gluten Free | Pyridoxal 5 Phosphate | Coenzyme B6 | By Horbaach

HORBÄACH
CL14551
1.85 X 1.85 X 3.60 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Carlyle 9.99

Features

P-5-P: Get premium quality and exceptional value from this metabolically active form of vitamin B-6

VEGETARIAN FORMULA: Delivers 100 mg of P-5-P in just two easy-to-take tablets

EXPERTLY CRAFTED: Our professional formula is backed by our commitment to purity and potency

HORBAACH MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!

NATURALLY FREE OF: Gluten, Wheat, Artificial Flavor, Artificial Sweetener, Preservatives & Non-GMO

Top 10 p5p dietary supplements Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Ez Melts 2
Jarrow Formulas 2
Horbäach 1
Igennus Healthcare Nutrition 1
Kal 1
Nature Made 1
Nature's Bounty 1

Top 10 p5p dietary supplements Brands Pie Chart


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We are dedicated to assisting our users in finding the right supplements Products based on their needs, saving them considerable time when choosing which p5p dietary supplements to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.