PickSmartly Review

Best Klaire Labs Probiotic Supplements in 2026

9.8 PM Score
Products Evaluated
19
Reviews Analyzed
4,756
Brands Ranked
1
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Navigating the world of digestive wellness can be overwhelming, especially when you encounter a brand as specialized as Klaire Labs. Unlike mass-market probiotic brands that focus on broad, general wellness, Klaire Labs has built its reputation on clinical precision and therapeutic-grade formulations. When you are looking for a probiotic supplement from this line, you aren't just looking for 'good bacteria'. You are looking for a targeted biological tool designed to address specific physiological imbalances. Whether you are managing gut permeability, recovering from antibiotic use, or seeking to support immune function, choosing the right strain and concentration is critical to seeing actual results.

Editor's Choice

Our Top Picks for Klaire Labs Probiotic Supplements

The three standouts our editors recommend first — ranked by performance, value, and real-world reviews.

Klaire Labs Ther-Biotic Complete - 25 Billion CFU Probiotic Supplement - Lactobacillus Rhamnosus + 11 Other Probiotic Species - Hypoallergenic Probiot...

Klaire Labs Ther-Biotic Complete Probiotic Supplement

4.6 (1,916 ratings)
KLAIRE LABS VI0052 0.20 Pounds

Reviews for KLAIRE LABS (PM Score)

9.8 PM Score
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  • High Strength & Hypoallergenic - Premium support blend of 12 safe, complementary and well-studied species to support optimal gut flora, immune & GI health. Hypoallergenic 25 billion CFU in a base of chicory-derived prebiotic inulin.*
  • Probiotic Survival Without Extra Additives - Ther-Biotic does not need additive-packed spheres or tablets to promote probiotic survival. Advanced InTactic technology helps live probiotics reach the small intestine and colon. Each bottle is formulated with sufficient overages, handled with care, and tested for potency that delivers on its promise.*
  • Protection From Stomach Acid - On exposure to stomach acid, an InTactic 'shield' forms a gel-like matrix surrounding the probiotics, protecting them from damage. On passage into the duodenum, InTactic is designed to break down and release live microorganisms for optimal efficacy.*
  • Diverse Strains, Diverse Benefits - Each probiotic species in Ther-Biotic Complete offers unique functions and, when combined, synergistic probiotic nutritional support for both the small and large intestines. Probiotic mechanisms include activity against undesirable flora, support for intestinal barrier integrity, immunity and a healthy inflammation response.*
  • Dairy-Free - Unlike many probiotics, Ther-Biotic probiotic species are grown on a plant based medium. Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

Klaire Labs Ther-Biotic Complete stands out because its InTactic technology ensures your probiotics actually survive the journey through stomach acid. I found the science behind this blend impressive. Instead of relying on bulky, additive-filled capsules, it uses a specialized gel-like matrix to shield the 25 billion CFU until they reach your small intestine and colon. It is a massive win for anyone with dietary sensitivities, as the entire formula is grown on a plant-based medium and is completely free from dairy, gluten, and common allergens like soy or nuts. By combining twelve distinct, well-studied species, this supplement provides a synergistic approach to supporting your intestinal barrier and immune response without the unnecessary fillers found in most drugstore options.

What We Like
InTactic survival technology
25 billion CFU
Twelve probiotic species
Hypoallergenic plant-based medium
Dairy-free formula
#2

Klaire Labs Biotagen Powder - Prebiotic Inulin, Beta-Glucan & Arabinogalactan to Support Gut Microbiota (30 Servings, 150 Grams)

Klaire Labs Biotagen Prebiotic Powder Support

4.7 (117 ratings)
KLAIRE LABS VI0082 2.36 X 2.36 X 2.36 Inches 0.63 Pounds

Reviews for KLAIRE LABS (PM Score)

9.7 PM Score
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  • A versatile prebiotic formula to optimize gut microbiota and support bowel and immune system function.*
  • Featuring chicory-derived inulin, larch arabinogalactan and purified yeast beta-glucan.*
  • Works synergistically with probiotics to promote intestinal microbiota balance.*
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and corn. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 Yes Yes Yes

Serious gut health enthusiasts who are already investing in high-end probiotics realize that those expensive supplements are only half the battle without the right fuel. Klaire Labs Biotagen Powder provides that essential foundation by utilizing a synergistic blend of chicory-derived inulin, larch arabinogalactan, and purified yeast beta-glucan. I love how this formula doesn't just sit there. It actively works to optimize your microbiota and support both bowel and immune functions. Because it is completely hypoallergenic and free from common allergens like gluten, dairy, and soy, it is a reliable choice for those with sensitive systems. It feels like a professional-grade tool for anyone looking to balance their intestinal environment without worrying about hidden artificial colors or preservatives.

What We Like
Triple prebiotic blend
Hypoallergenic formula
Supports immune function
No artificial additives
Practitioner trusted

Klaire Labs Biotagen - Prebiotic Inulin, Beta-Glucan & Arabinogalactan to Support Gut Microbiota (120 Capsules)

Klaire Labs Biotagen Prebiotic Microbiota Support

4.7 (106 ratings)
KLAIRE LABS K-BTGC 2.00 X 2.00 X 3.00 Inches 0.30 Pounds

Reviews for KLAIRE LABS (PM Score)

9.7 PM Score
Buy on Amazon
  • A versatile prebiotic formula to optimize gut microbiota and support bowel and immune system function.*
  • Featuring chicory-derived inulin, larch arabinogalactan and purified yeast beta-glucan.*
  • Works synergistically with probiotics to promote intestinal microbiota balance.*
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and corn. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 Yes Yes Yes

Serious gut health enthusiasts who struggle to maintain a stable microbiome need Klaire Labs Biotagen to bridge the gap between probiotic intake and actual colonization. While most people focus solely on adding good bacteria, this formula prioritizes the fuel those bacteria require through a synergistic blend of chicory-derived inulin, larch arabinogalactan, and purified yeast beta-glucan. It acts as a high-quality foundation that works alongside your existing probiotics to optimize intestinal balance and immune function. I particularly value how clean this capsule is. It is a truly hypoallergenic option that avoids common irritants like gluten, corn, and soy. Since the brand has been physician-developed since 1969, you can feel confident that this isn't just another trendy supplement, but a professional-grade tool for digestive wellness.

What We Like
Triple prebiotic blend
Supports immune function
Hypoallergenic formula
Physician developed
No artificial additives
#4

Klaire Labs Lactoprime Plus Probiotic - 25 Billion High CFU for Carb-Sensitive Men & Women, 7 Lactobacillus and 5 Bifidobacterium Blend, FODMAP Compli...

Klaire Labs Lactoprime Plus Probiotic Blend

4.7 (220 ratings)
KLAIRE LABS

Reviews for KLAIRE LABS (PM Score)

9.7 PM Score
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  • 25 billion CFU probiotic blend of 7 Lactobacillus and 5 Bifidobacterium supplied in a base of purified plant cellulose.
  • Specifically formulated without inulin or other fermentable carbohydrates, making it suitable for carbohydrate-sensitive individuals.*
  • Supports gastrointestinal and immune health*
  • Hypoallergenic* and non-GMO. Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

You are sitting at a dinner table, eyeing a delicious meal but hesitating because you know the typical prebiotic fillers in most supplements often trigger bloating and discomfort. Klaire Labs Lactoprime Plus solves this specific frustration by omitting inulin and other fermentable carbohydrates that frequently cause issues for carb-sensitive individuals. This 25 billion CFU formula relies on a precise blend of seven Lactobacillus and five Bifidobacterium strains delivered in a gentle plant cellulose base. It is a highly specialized option for anyone managing complex dietary sensitivities, especially since it is hypoallergenic and free from common allergens like gluten, dairy, and soy. Because this brand has been developed alongside healthcare practitioners since 1969, it feels less like a generic supplement and more like a professional-grade tool for supporting long-term gastrointestinal and immune health.

What We Like
25 billion CFU
Carbohydrate sensitive formula
FODMAP compliant
Hypoallergenic blend
Dairy-free capsules
#5

Klaire Labs Saccharomyces Boulardii Probiotic - Acid Resistant & Shelf-Stable Probiotic Supplement to Help Support Healthy Yeast Balance, Immune & Dig...

Klaire Labs Saccharomyces Boulardii Probiotic Supplement

4.6 (685 ratings)
KLAIRE LABS 9O-R0NR-FAKT 2.00 X 2.00 X 4.00 Inches

Reviews for KLAIRE LABS (PM Score)

9.6 PM Score
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  • A powerful yeast probiotic supplied in a based of plant cellulose.
  • American Type Culture Collection (ATCC) certified and freeze-dried to maintain maximum strength and viability.*
  • This hardy species is acid-resistant and temperature tolerant.
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
The_Smart_Shoppers 5.10 Yes Yes Yes

Most probiotics die long before they ever reach your gut, but this yeast-based formula actually thrives where others fail. Because Saccharomyces Boulardii is naturally acid-resistant and temperature tolerant, you aren't just swallowing expensive, inactive capsules. Klaire Labs uses ATCC-certified, freeze-dried strains on a plant cellulose base to ensure maximum viability from the first dose to the last. It is a remarkably hardy supplement designed to support yeast balance and digestive health without the usual filler concerns. Since the formula is completely hypoallergenic and free from gluten, dairy, and soy, it fits seamlessly into highly sensitive dietary regimens. It is the kind of professional-grade stability you typically only find in clinical settings, making it a reliable choice for long-term wellness.

What We Like
Acid-resistant formula
Temperature tolerant
ATCC certified
Hypoallergenic
Shelf-stable

Klaire Labs Vital-10 Probiotic - 10 Species Supplement with Lactobacillus, Bifidobacterium & Streptococcus for Immune, Digestive, GI & Colon Support -...

Klaire Labs Vital-10 Probiotic Supplement

4.6 (437 ratings)
KLAIRE LABS V085-10 3.00 X 3.00 X 3.00 Inches

Reviews for KLAIRE LABS (PM Score)

9.6 PM Score
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  • Broad-acting, 10-species probiotic formula offers comprehensive benefits for the healthy function of the entire gastrointestinal tract.*
  • The Lactobacillus species normally predominate in the small intestine while the Bifidobacterium species are important for the colon.*
  • This maintenance-dose vegetarian capsule supplies 5 billion CFU in a base of chicory-derived inulin.
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

Sensitive individuals with complex dietary restrictions need Klaire Labs Vital-10 in their daily wellness toolkit. This isn't just a generic gut supplement. It’s a sophisticated, broad-acting formula that targets the entire gastrointestinal tract by balancing Lactobacillus for the small intestine and Bifidobacterium for the colon. I appreciate how it avoids the usual filler, utilizing a chicory-derived inulin base to deliver 5 billion CFU per vegetarian capsule. Because it is strictly hypoallergenic—meaning no gluten, soy, dairy, or nuts—it removes the guesswork for those prone to inflammatory responses. Since the brand has been working closely with healthcare practitioners since 1969, you can feel confident that this maintenance dose is built on clinical reliability rather than marketing hype.

What We Like
Ten probiotic species
Hypoallergenic formula
Chicory-derived inulin
Vegetarian capsules
Five billion CFU
#7

Klaire Labs Ther-Biotic Kids Chewable Probiotic - 25b CFU Lactobacillus + Bifidobacterium Probiotics for Kids - GI + Immune Support, Cherry Flavor - H...

Klaire Labs Ther-Biotic Kids Cherry Probiotic Chewables

4.5 (576 ratings)
KLAIRE LABS K-TCC 6.00 X 3.00 X 3.00 Inches 0.05 Pounds

Reviews for KLAIRE LABS (PM Score)

9.5 PM Score
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  • Multispecies chewable probiotic with 25 billion CFU per tablet. Suitable for children over age 2, or even adults.*
  • Great tasting, natural cherry flavor. Sweetened with xylitol.
  • These eight Lactobacillus and Bifidobacterium species have been intensively researched and clinically shown to support gastrointestinal health in children.*
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

Parents dealing with sensitive stomachs or frequent seasonal sniffles need a probiotic that actually delivers clinical-grade potency without the allergy risks. Klaire Labs has developed a powerhouse chewable that packs 25 billion CFU per tablet, utilizing eight specific Lactobacillus and Bifidobacterium species to target GI and immune health. Unlike many kid-friendly supplements that rely on artificial fillers, these tablets feature a natural cherry flavor sweetened with xylitol, making them a genuine treat for children over age two. Because the formula is strictly hypoallergenic and free from dairy, gluten, soy, and nuts, it is a safe, high-standard option for families managing multiple dietary restrictions. It is a professional-grade supplement that bridges the gap between clinical efficacy and kid-approved taste.

What We Like
25 billion CFU
Natural cherry flavor
Eight probiotic species
Hypoallergenic formula
Dairy-free tablets

Klaire Labs Ther-Biotic Factor 1 Probiotic - Lactobacillus Rhamnosus Single Species Probiotic - 20 Billion CFU - Dairy-Free Gut + Immune Support - L R...

Klaire Labs Ther-Biotic Factor 1 Lactobacillus Rhamnosus Probiotic

4.6 (98 ratings)
KLAIRE LABS V771-06 2.00 X 2.00 X 3.80 Inches 0.25 Pounds

Reviews for KLAIRE LABS (PM Score)

9.5 PM Score
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  • Lactobacillus rhamnosus, 20 billion CFUs per capsule in an inulin base.*
  • L. rhamnosus has been recognized for robust L(+) lactic acid production and immune support.*
  • Proprietary InTactic technology helps ensure maximum delivery of live probiotics throughout the intestinal tract.*
  • Hypoallergenic* product with none of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

Klaire Labs Ther-Biotic Factor 1 delivers a concentrated, single-species punch of 20 billion CFUs of Lactobacillus rhamnosus to target gut and immune health. What sets this apart from the crowded drugstore aisle is the proprietary InTactic technology, which acts as a delivery system to ensure those live probiotics actually reach your intestinal tract where they can do the most good. It is an incredibly clean formula, making it a reliable choice for those navigating multiple food sensitivities since it is completely hypoallergenic and free from gluten, dairy, and soy. Because Klaire Labs has worked closely with physicians since 1969, you can feel confident that this isn't just another supplement, but a practitioner-grade tool designed for specific, high-quality lactic acid production.

What We Like
20 billion CFUs
InTactic delivery technology
Hypoallergenic formula
Single species probiotic
Dairy-free support

Klaire Labs Pro-5 Probiotic - 25 Billion CFU High Dose Multispecies Gut Recolonization Support for Men & Women, Hypoallergenic & Dairy-Free (60 Capsul...

Klaire Labs Pro-5 High Dose Probiotic Capsules

4.4 (113 ratings)
KLAIRE LABS PRO5 3.00 X 3.00 X 3.00 Inches

Reviews for KLAIRE LABS (PM Score)

9.4 PM Score
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  • 25 billion CFU blend featuring 5 probiotic species to support GI colonization.*
  • Includes Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium bifidum, Streptococcus thermophilus, and Lactobacillus bulgaricus.
  • These transient and colonizing species have high tolerance to stomach acid and bile, which is important for maintaining viability in the intestinal environment.*
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

Anyone struggling with chronic digestive imbalances needs a probiotic that actually survives the journey to the gut. Klaire Labs Pro-5 delivers a heavy-hitting 25 billion CFU blend that focuses on real intestinal colonization rather than just passing through. I was particularly impressed by the specific selection of five essential species, including Lactobacillus acidophilus and Bifidobacterium bifidum, which are engineered to withstand harsh stomach acid and bile. This isn't just a generic supplement. It is a practitioner-grade formula designed for serious GI support. Because it is completely hypoallergenic and free from common triggers like gluten, dairy, and soy, it serves as a safe, reliable option for those with highly sensitive systems who cannot risk reacting to unnecessary fillers or artificial additives.

What We Like
25 billion CFU
Five probiotic species
Acid resistant
Hypoallergenic formula
Dairy-free

Klaire Labs Ther-Biotic Detoxification Support Probiotic - 50 Billion CFU The Original Hypoallergenic Probiotic for Support During Detox Programs (60...

Klaire Labs Ther-Biotic Detoxification Support Probiotic

KLAIRE LABS 43211-849 2.00 X 3.00 X 1.00 Inches

Reviews for KLAIRE LABS (PM Score)

9.3 PM Score
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  • 50 billion CFU probiotic blend to support the body's natural detoxification process.*
  • Free of D(-)-lactic acid-producing species.
  • Proprietary InTactic technology helps ensure maximum delivery of live probiotics throughout the intestinal tract.*
  • Hypoallergenic* and non-GMO. Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

Can a probiotic actually assist with the heavy lifting of a detox program? Klaire Labs Ther-Biotic Detoxification Support is specifically formulated to tackle that exact challenge with a potent 50 billion CFU blend. What really sets this apart from your standard drugstore supplement is the proprietary InTactic technology, which is designed to ensure those live cultures actually survive the journey to your intestinal tract. It is a highly specialized formula that excludes D(-)-lactic acid-producing species, making it much more targeted than generic options. Because it is completely hypoallergenic and free from common allergens like gluten, soy, and dairy, it feels like a professional-grade tool rather than a mass-market afterthought. It is the kind of reliable support you want when your body is undergoing significant internal changes.

What We Like
50 billion CFU
InTactic delivery technology
Hypoallergenic formula
Non-GMO ingredients
No common allergens
#11

Klaire Labs Ther-Biotic Factor 6 Probiotic - Ultra-Strength 100 Billion CFU Probiotics for Men & Women - Supports Immune, Digestive & Colon Health - H...

Klaire Labs Ther-Biotic Factor 6 Probiotic

4.5 (78 ratings)
KLAIRE LABS VI0099 3.00 X 3.00 X 3.00 Inches 1.00 Pounds

Reviews for KLAIRE LABS (PM Score)

8.4 PM Score
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  • 100 billion CFUs of freeze-dried probiotic cultures per capsule, provided in a base of purified plant cellulose.
  • Three Bifidobacterium and three Lactobacillus species for gastrointestinal support.*
  • Proprietary InTactic® technology helps ensure maximum delivery of live probiotics throughout the intestinal tract.*
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

Serious gut health enthusiasts requiring high-potency microbial support should look no further than this ultra-strength formula. What sets this apart from your standard drugstore supplement is the massive 100 billion CFU count per capsule, delivered via a sophisticated blend of three Bifidobacterium and three Lactobacillus species. I was particularly impressed by the proprietary InTactic technology, which is engineered to ensure those live cultures actually survive the journey to your intestinal tract rather than being lost in transit. Because it uses a purified plant cellulose base and is completely hypoallergenic, it is an exceptionally clean option for anyone dodging gluten, dairy, or soy. It feels like a professional-grade tool rather than a casual wellness add-on, making it ideal for those prioritizing precise digestive and immune maintenance.

What We Like
100 billion CFUs
InTactic delivery technology
Six probiotic species
Hypoallergenic formula
Dairy and gluten free

Klaire Labs Ther-Biotic Metabolic Formula Probiotic - Supports Metabolism + Immune System - Vegetarian Probiotics - Hypoallergenic, Dairy-Free (60 Cap...

Klaire Labs Ther-Biotic Metabolic Probiotic Formula

KLAIRE LABS K-MBS

Reviews for KLAIRE LABS (PM Score)

7.9 PM Score
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  • 25 billion CFU, multispecies probiotic blend to support healthy energy metabolism.*
  • Provides four Lactobacillus and three Bifidobacterium species in a plant cellulose base.*
  • Supports healthy immune and gut barrier function.*
  • Hypoallergenic* and free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

The clean, plant-based capsule slides down easily without the chalky residue often found in cheaper supplements. I was immediately drawn to the clinical pedigree behind this formula, especially since Klaire Labs has been working alongside physicians since 1969. This isn't just a basic gut supplement. It's a targeted 25 billion CFU blend featuring four Lactobacillus and three Bifidobacterium species specifically designed to support energy metabolism and gut barrier function. Because it uses a plant cellulose base and is strictly hypoallergenic, it is a relief to find a high-potency option that is completely free from milk, gluten, soy, and common allergens. It feels like a professional-grade tool for anyone looking to fortify both their immune system and metabolic health simultaneously.

What We Like
25 billion CFU
Metabolic support
Hypoallergenic formula
Multispecies probiotic blend
Dairy-free capsules
#13

Klaire Labs Galactomune - Prebiotic Blend with Beta-Glucan & Galactooligosaccharides for Immune Support, Soy & Gluten-Free (60 Capsules)

Klaire Labs Galactomune Prebiotic Immune Support Capsules

KLAIRE LABS K-GALC 2.36 X 2.36 X 2.36 Inches

Reviews for KLAIRE LABS (PM Score)

7.5 PM Score
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  • Immune-supportive prebiotic formula to promote natural resistance.*
  • A viable alternative to chicory-derived inulin-type fructans, and a good choice of prebiotic for all age groups.*
  • Featuring galactooligosaccharides (GOS) and beta-glucan in vegetarian capsules.
  • Contains Milk and Fish (bonito). Non-GMO and free of the following common allergens: eggs, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 Yes Yes Yes

People struggling with the bloating often caused by traditional inulin-type fructans need to switch to Klaire Labs Galactomune immediately. Unlike many common prebiotics derived from chicory, this formula utilizes a specific blend of galactooligosaccharides and beta-glucan to support your natural immune resistance without the typical digestive discomfort. It is a sophisticated, vegetarian-friendly option that works across all age groups. I appreciate that it avoids the usual suspects like soy, gluten, and artificial additives, making it a much cleaner choice for sensitive systems. Since the brand has been working alongside healthcare practitioners since 1969, you can feel confident that this isn't just another trendy supplement, but a professionally developed tool for maintaining your internal defenses.

What We Like
Immune-supportive prebiotic blend
Beta-glucan and GOS
Chicory-free alternative
Soy and gluten-free
Practitioner-developed formula

Klaire Labs L. Acidophilus - 3 Billion CFU Lactobacillus Probiotic, Pure SCD Compliant Formula for Men & Women, Hypoallergenic & Non-Dairy (100 Capsul...

Klaire Labs L. Acidophilus Probiotic Capsules

KLAIRE LABS

Reviews for KLAIRE LABS (PM Score)

6.5 PM Score
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  • SDC™ compliant formula featuring Lactobacillus acidophilus in a base of purified plant cellulose.*
  • This hardy species is provided in a potency of 3 billion CFUs per capsule.
  • L. acidophilus can aid digestion and absorption of nutrients, help stabilize bowel function, and produce lactase enzyme.*
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

Can a single strain truly be the cornerstone of a balanced digestive system? Klaire Labs L. Acidophilus delivers a targeted 3 billion CFU dose designed specifically to support nutrient absorption and stabilize bowel function. What sets this formula apart is its extreme purity. It is SCD compliant and uses a purified plant cellulose base rather than unnecessary fillers. Because it is completely hypoallergenic, you don't have to worry about common triggers like gluten, dairy, or soy interfering with your gut health. It is the kind of reliable, practitioner-trusted supplement that focuses on what matters most—the hardy Lactobacillus acidophilus—without the clutter of artificial colors or preservatives. It feels less like a generic drugstore find and more like a professional-grade tool for digestive wellness.

What We Like
3 billion CFUs
SCD compliant formula
Hypoallergenic ingredients
Non-dairy base
No artificial additives

Klaire Labs L. Acidophilus - 3 Billion CFU Lactobacillus Probiotic, Pure SCD Compliant Formula for Men & Women, Hypoallergenic & Non-Dairy (100 Capsul...

Klaire Labs L. Acidophilus 3 Billion CFU Probiotic

KLAIRE LABS VI0085 0.94 Pounds

Reviews for KLAIRE LABS (PM Score)

6.5 PM Score
Buy on Amazon
  • SDC™ compliant formula featuring Lactobacillus acidophilus in a base of purified plant cellulose.*
  • This hardy species is provided in a potency of 3 billion CFUs per capsule.
  • L. acidophilus can aid digestion and absorption of nutrients, help stabilize bowel function, and produce lactase enzyme.*
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

Most probiotic supplements clutter your gut with unnecessary fillers, but Klaire Labs L. Acidophilus focuses on pure, targeted support. I found that this formula stands out because it uses a purified plant cellulose base rather than common dairy-derived carriers. With 3 billion CFUs of this hardy Lactobacillus species per capsule, it is designed to assist with nutrient absorption, stabilize bowel function, and even help produce the lactase enzyme. It is a rare find for anyone following a strict SCD compliant diet or managing multiple sensitivities, as it is entirely hypoallergenic and free from gluten, soy, and dairy. Since the brand has been working closely with healthcare practitioners since 1969, you can tell they prioritize clinical integrity over marketing fluff.

What We Like
3 billion CFUs
SCD compliant formula
Hypoallergenic ingredients
Dairy and gluten free
Plant cellulose base

Klaire Labs ABX Support Probiotic - 10 Billion CFU Supplement for Support During Antibiotic Therapy, Hypoallergenic & Non-Dairy (60 Capsules)

Klaire Labs ABX Support Probiotic Supplement

KLAIRE LABS K-ABX-60 2.00 X 3.00 X 2.00 Inches 0.02 Pounds

Reviews for KLAIRE LABS (PM Score)

6.4 PM Score
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  • A novel blend of 4 probiotic species documented to support the normal gastrointestinal microbiota.*
  • 10 billion CFU supplied in a base of chicory-derived inulin.
  • A carefully researched blend of the non- pathogenic yeast Saccharomyces boulardii with Lactobacillus rhamnosus, Bifidobacterium bifidum, and Bifidobacterium breve.*
  • Hypoallergenic* and non-GMO. Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 No No No

Klaire Labs ABX Support Probiotic delivers a specialized microbial defense designed specifically to safeguard your gut during antibiotic therapy. This isn't just a standard probiotic. It utilizes a targeted blend of 10 billion CFU, featuring the non-pathogenic yeast Saccharomyces boulardii alongside Lactobacillus rhamnosus and two Bifidobacterium strains. I found the inclusion of chicory-derived inulin as a base particularly smart for supporting these beneficial species. Because it is hypoallergenic and free from common triggers like dairy, gluten, and soy, it feels like a much safer choice for those with sensitive systems or dietary restrictions. It is clear why healthcare practitioners have leaned on this brand since 1969, as the formula prioritizes purity by stripping out artificial colors and preservatives while focusing on documented gastrointestinal support.

What We Like
10 billion CFU
Saccharomyces boulardii blend
Hypoallergenic formula
Non-dairy and gluten-free
Chicory-derived inulin base

Klaire Labs Pure Saccharomyces Boulardii Powder - Probiotic Supplement to Support Healthy Yeast Balance - Digestive + Immune Support - Hypoallergenic...

Klaire Labs Pure Saccharomyces Boulardii Probiotic Powder

KLAIRE LABS SBP-180 0.50 Pounds

Reviews for KLAIRE LABS (PM Score)

5.1 PM Score
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  • Pure, single ingredient Saccharomyces boulardii powder.
  • With a dual scoop for measuring accuracy, this clean-label formulation is particularly effective and uniquely convenient for use in high-potency titration protocols.
  • Supplies 9 billion CFU per small scoop & 45 billion CFU per large scoop.
  • Hypoallergenic product with none of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 Yes Yes Yes

Maintaining a healthy yeast balance and supporting digestive resilience often requires a level of precision that standard capsules just can't provide. This Klaire Labs powder is a standout because it offers a pure, single-ingredient solution designed for high-potency titration protocols. I found the dual-scoop system incredibly practical. You can easily dose out a gentle 9 billion CFU for kids or scale up to a robust 45 billion CFU for adults. Because it is completely hypoallergenic and free from common allergens like gluten, dairy, and soy, it feels exceptionally clean. It is clear why healthcare practitioners have leaned on this brand since 1969, as the formulation avoids all the artificial fillers and preservatives that typically clutter the supplement aisle.

What We Like
Dual measuring scoops
Single ingredient formula
Hypoallergenic composition
High potency dosing
No artificial additives

Klaire Labs Ther-Biotic Synbiotic Probiotic (30 Capsules) + Vital-Zymes Digestive Enzymes Bundle (120 Count) - Low-FODMAP Probiotic Supplement + Diges...

Klaire Labs Synbiotic Probiotic and Vital-Zymes Enzyme Bundle

KLAIRE LABS

Reviews for KLAIRE LABS (PM Score)

5.1 PM Score
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  • Two product digestion support bundle. Ther-biotic Synbiotic is a probiotic Made for Sensitive Stomachs - Powerful probiotic supplement specifically designed for those with restricted diets, sensitive stomachs and food sensitivities.*
  • Clinically Proven Probiotics + a Low-FODMAP Prebiotic - Includes seven to support healthy digestion, GI comfort, and immune function.* Combined with a prebiotic to offer more profound effects on the microbiome than probiotics alone.*
  • Shelf Stable 50 Billion CFU. Delayed-release capsule technology delivers live probiotics where they’re needed most, while patented packaging protects probiotics at room temperature through expiry date. No refrigeration needed.
  • Vital-Zymes is a powerful 20 Enzyme Blend. Many enzyme supplements offer limited enzymes such as protease, amylase, and lipase, but lack more specific enzymes needed for optimal digestion. This multi-enzyme, high-strength complex is designed to address a full range of foods found in a typical meal.*
  • These digestive enzymes supply serratia peptidase, DPP-IV activity, disaccharidases and more for a full complement of enzymes that lend maximum support for breaking down foods including proteins, fats, carbs, casein, lactose, gluten, sugars, and fibers. These enzymes are designed to support intestinal function, which may be related to bloating, fullness, or discomfort associated with occasional gas.*
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FortressBrand Wellness 9.93 Yes Yes No

It is easy to feel cynical about digestive supplements that promise the world, but this Klaire Labs duo actually targets the specific mechanics of gut discomfort. Instead of just throwing random bacteria at the problem, the Ther-biotic Synbiotic uses a Low-FODMAP prebiotic to ensure the seven probiotic strains actually thrive in sensitive environments. I was particularly impressed by the shelf-stable, delayed-release technology, which means you aren't wrestling with a refrigerator just to keep your microbes alive. When you pair that with the Vital-Zymes blend, you get a massive 20-enzyme toolkit that handles everything from gluten and lactose to complex proteins. It is a sophisticated, dual-action approach for anyone tired of the usual bloating and post-meal heaviness.

What We Like
Low-FODMAP prebiotic
20-enzyme blend
Delayed-release technology
Shelf stable
50 billion CFU

Klaire Labs Ther-Biotic Complete - 25 Billion CFU Probiotic Supplement - Gut Health, Digestive + Immune Support - Hypoallergenic Probiotics for Men +...

Klaire Labs Ther-Biotic Complete Probiotic Supplement

KLAIRE LABS VBPUKALIZINW4177 0.42 pounds

Reviews for KLAIRE LABS (PM Score)

0.0 PM Score
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  • High Strength & Hypoallergenic - Premium support blend of 12 safe, complementary and well-studied species to support optimal gut flora, immune & GI health. Hypoallergenic 25 billion CFU in a base of chicory-derived prebiotic inulin.*
  • Probiotic Survival Without Extra Additives - Ther-Biotic does not need additive-packed spheres or tablets to promote probiotic survival. Advanced InTactic technology helps live probiotics reach the small intestine and colon. Each bottle is formulated with sufficient overages, handled with care, and tested for potency that delivers on its promise.*
  • Protection From Stomach Acid - On exposure to stomach acid, an InTactic 'shield' forms a gel-like matrix surrounding the probiotics, protecting them from damage. On passage into the duodenum, InTactic is designed to break down and release live microorganisms for optimal efficacy.*
  • Diverse Strains, Diverse Benefits - Each probiotic species in Ther-Biotic Complete offers unique functions and, when combined, synergistic probiotic nutritional support for both the small and large intestines. Probiotic mechanisms include activity against undesirable flora, support for intestinal barrier integrity, immunity and a healthy inflammation response.*
  • Dairy-Free - Unlike many probiotics, Ther-Biotic probiotic species are grown on a plant based medium. Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Superior Supplement Store 9.01 No No No

Most high-potency probiotics rely on bulky, additive-heavy coatings just to survive the trip through your digestive tract, but Klaire Labs takes a much smarter approach. Instead of packing capsules with unnecessary fillers, they use InTactic technology to create a protective gel-like shield around the microorganisms. This ensures the 25 billion CFU actually reach your small intestine and colon rather than being destroyed by stomach acid prematurely. I love that it utilizes a chicory-derived prebiotic inulin base and a diverse blend of 12 well-studied species to target both gut flora and immune response. Because the strains are grown on a plant-based medium, it is a rare find that is completely free of dairy, gluten, and common allergens, making it a reliable choice for those with highly sensitive systems.

What We Like
InTactic survival technology
25 billion CFU
Hypoallergenic formula
Dairy-free medium
12 probiotic species
Buying Guide

A Guide to Selecting the Best klaire labs probiotic supplements

A Guide to Selecting the Best klaire labs probiotic supplements

Understanding Strain Specificity and Diversity

The most important factor when selecting a Klaire Labs probiotic is understanding that not all bacteria serve the same purpose. A supplement designed for bloating and gas will have a vastly different microbial profile than one designed for systemic immune support. When reviewing the label, look beyond the total CFU (Colony Forming Units) count. While a high CFU count is generally a sign of potency, the specific strains—such as Lactobacillus acidophilus or Bifidobacterium infantis—are what dictate the efficacy. For targeted gut health, you want a diverse array of strains that can colonize different sections of the digestive tract. If your goal is therapeutic intervention, prioritize formulations that list specific, researched strains rather than generic categories.

CFU Count and Potency Stability

In the realm of high-end probiotics, the 'dosage' is measured in CFUs. However, a high number on the bottle is meaningless if the bacteria are not viable by the time they reach your gut. Klaire Labs is known for its commitment to stability, but as a consumer, you should look for products that utilize advanced delivery technologies. Some formulations are designed to survive the harsh acidic environment of the stomach to ensure the microbes reach the small and large intestines intact. When deciding between two products, consider the intended duration of use. Some formulations are meant for short-term 'resetting' of the microbiome, while others are designed for daily, long-term maintenance.

Targeted Formulations: Specialized Needs

One of the primary reasons to choose this specific brand is their segmented approach to health. You should categorize your buying decision based on your primary symptom or health goal:

  • Digestive Regularity: Look for blends rich in Bifidobacterium strains, which are essential for processing fiber and maintaining bowel regularity.
  • Immune Support: Seek out combinations that include specific Lactobacillus strains known for their interaction with the mucosal immune system.
  • Post-Antibiotic Recovery: If you are recovering from medication, prioritize a broad-spectrum probiotic that replenishes a wide variety of lost microbial diversity.
  • Gut Barrier Support: For those focusing on intestinal integrity, look for synergistic blends that may include prebiotics to feed the beneficial bacteria.

Consideration of Additives and Dietary Restrictions

Because Klaire Labs often caters to individuals with sensitive systems or specific dietary requirements, you must check for 'clean label' attributes. Many users seeking these supplements are also managing food sensitivities. Pay close attention to the 'Other Ingredients' section. High-quality probiotic supplements should be free from common allergens like gluten, dairy, soy, and artificial colors or flavors. If you are following a strict vegan or paleo lifestyle, ensure the capsule material (such as cellulose vs. gelatin) aligns with your dietary needs. A truly effective probiotic should solve a health issue without introducing new inflammatory triggers through unnecessary fillers.

Final Recommendation Logic

To make the final selection, follow this hierarchy: First, identify your primary symptom. Second, match that symptom to the specific strain profile provided in the product description. Third, verify that the CFU count is appropriate for your level of need (e.g., a maintenance dose vs. a therapeutic dose). Finally, ensure the supplement's purity profile matches your dietary restrictions. By following this logic, you move from guesswork to a clinical, results-oriented approach to supplementation.

Ready to choose?

Jump back to our ranked picks or compare the shortlist side by side.

Frequently Asked Questions

Quick answers about Klaire Labs Probiotic Supplements before you buy.

Most Klaire Labs probiotic strains are shelf-stable, but for maximum efficacy, it is recommended to store them in a cool, dry place away from direct sunlight. Some specialized formulas may require refrigeration.

Yes, most Klaire Labs formulations are designed to withstand stomach acid, but taking them either just before a meal or with a light meal is often recommended to optimize transit to the intestines.

Yes, the brand is well-known for its commitment to purity, with the vast majority of their probiotic lines being non-GMO, gluten-free, and free from common allergens.

While some users notice changes in digestion within days, it typically takes 2 to 4 weeks of consistent daily use to allow the beneficial bacteria to colonize the gut effectively.

Some specific Klaire Labs formulas are 'synbiotics,' meaning they include both probiotics and prebiotics (food for the bacteria) to enhance colonization, while others are pure probiotic strains.

While Klaire Labs focuses on high-quality ingredients, you should always consult your healthcare provider before starting any new supplement regimen during pregnancy or lactation.

Generally, probiotics do not interfere with most medications, but if you are taking immunosuppressants or antibiotics, consult a doctor to determine the best timing for your doses.

The premium pricing reflects the use of clinically studied, high-CFU (colony-forming unit) strains and rigorous testing for purity, potency, and the absence of unnecessary fillers.
Research & Insights

Our Analysis of Klaire Labs Probiotic Supplements

4,756 Reviews Analyzed
19 Products Evaluated
7.8 Avg PM Score
1 Brands Ranked

Top 10 Klaire Labs Probiotic Supplements Brands on Amazon

Share of top-ranked products by brand, from our editorial analysis.

  1. 01 Klaire Labs 19 (100%)

What Our Analysis Found

We've carried out a comprehensive analysis of 4,756 reviews on Klaire Labs Probiotic Supplements, using our selection criteria to identify the best options in the vitamins & dietary supplements. Our findings reveal that most customers typically select Klaire Labs Probiotic Supplements priced around $64.43.

Our team of expert editors reviewed these high-quality items and handpicked the top 19 Klaire Labs Probiotic Supplements for your consideration..

We are dedicated to assisting our users in finding the right supplements Products based on their needs, saving them considerable time when choosing which Klaire Labs Probiotic Supplements to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.

Side by Side

Comparison Table

Compare the top 19 picks at a glance — select a column to sort.

# Product Brand PM Score Rating Where to Buy
1 Klaire Labs Ther-Biotic Complete Probiotic Supplement Klaire Labs 9.8 4.6 (1,916) Buy on Amazon
2 Klaire Labs Biotagen Prebiotic Powder Support Klaire Labs 9.7 4.7 (117) Buy on Amazon
3 Klaire Labs Biotagen Prebiotic Microbiota Support Klaire Labs 9.7 4.7 (106) Buy on Amazon
4 Klaire Labs Lactoprime Plus Probiotic Blend Klaire Labs 9.7 4.7 (220) Buy on Amazon
5 Klaire Labs Saccharomyces Boulardii Probiotic Supplement Klaire Labs 9.6 4.6 (685) Buy on Amazon
6 Klaire Labs Vital-10 Probiotic Supplement Klaire Labs 9.6 4.6 (437) Buy on Amazon
7 Klaire Labs Ther-Biotic Kids Cherry Probiotic Chewables Klaire Labs 9.5 4.5 (576) Buy on Amazon
8 Klaire Labs Ther-Biotic Factor 1 Lactobacillus Rhamnosus Probiotic Klaire Labs 9.5 4.6 (98) Buy on Amazon
9 Klaire Labs Pro-5 High Dose Probiotic Capsules Klaire Labs 9.4 4.4 (113) Buy on Amazon
10 Klaire Labs Ther-Biotic Detoxification Support Probiotic Klaire Labs 9.3 4.3 (116) Buy on Amazon
11 Klaire Labs Ther-Biotic Factor 6 Probiotic Klaire Labs 8.4 4.5 (78) Buy on Amazon
12 Klaire Labs Ther-Biotic Metabolic Probiotic Formula Klaire Labs 7.9 4.3 (72) Buy on Amazon
13 Klaire Labs Galactomune Prebiotic Immune Support Capsules Klaire Labs 7.5 4.2 (66) Buy on Amazon
14 Klaire Labs L. Acidophilus Probiotic Capsules Klaire Labs 6.5 4.2 (46) Buy on Amazon
15 Klaire Labs L. Acidophilus 3 Billion CFU Probiotic Klaire Labs 6.5 4.2 (46) Buy on Amazon
16 Klaire Labs ABX Support Probiotic Supplement Klaire Labs 6.4 4.2 (44) Buy on Amazon
17 Klaire Labs Pure Saccharomyces Boulardii Probiotic Powder Klaire Labs 5.1 4.1 (19) Buy on Amazon
18 Klaire Labs Synbiotic Probiotic and Vital-Zymes Enzyme Bundle Klaire Labs 5.1 5.0 (1) Buy on Amazon
19 Klaire Labs Ther-Biotic Complete Probiotic Supplement Klaire Labs 0.0 0.0 Buy on Amazon