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Best Reactions In Organic Chemistry Books in 2026

9.8 PM Score
Products Evaluated
15
Reviews Analyzed
1,405
Brands Ranked
9
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Mastering organic chemistry requires more than just memorizing functional groups. It demands a deep, intuitive understanding of how electrons move and how molecular structures transform. Reaction books serve as the fundamental roadmap for this journey, transitioning a student or researcher from simple rote learning to the predictive power of mechanistic reasoning. Whether you are preparing for advanced qualifying exams, navigating a laboratory synthesis, or teaching introductory coursework, selecting the right text is the difference between a chaotic collection of arrows and a coherent mental framework of chemical reactivity.

Editor's Choice

Our Top Picks for Reactions In Organic Chemistry Books

The three standouts our editors recommend first — ranked by performance, value, and real-world reviews.

Reactions: An Illustrated Exploration of Elements, Molecules, and Change in the Universe, Book 3 of 3

Reactions: An Illustrated Exploration of Elements by Black Dog & Leventhal

4.8 (891 ratings)
BLACK DOG & LEVENTHAL 980072461 10.50 X 0.88 X 10.38 Inches 2.80 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Reactions: An Illustrated Exploration of Elements, Molecules, and Change in the Universe is a visual masterpiece that brings the complex world of chemistry to life. As the third installment in this captivating series from Black Dog & Leventhal, this book moves beyond simple definitions to show how the fundamental building blocks of our world actually interact. Instead of feeling like a dry textbook, the illustrated approach makes understanding molecular change feel intuitive and engaging. It is a rare find that manages to be academically substantial while remaining visually stunning enough to sit on a coffee table. If you have followed the previous volumes, this conclusion provides a satisfying deep dive into the transformative processes that shape our entire universe.

What We Like
Illustrated scientific exploration
Third series volume
Molecular change focus
Visual chemistry guide
#2

Advanced Organic Chemistry: Part B: Reaction and Synthesis

Springer Advanced Organic Chemistry Part B

4.7 (151 ratings)
SPRINGER 22756279 7.50 X 2.50 X 10.00 Inches 5.32 Pounds

Reviews for SPRINGER (PM Score)

9.7 PM Score
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Amazon.com 9.68 Yes Yes Yes

A graduate student hunched over a complex multi-step synthesis diagram suddenly finds the missing mechanistic link within these pages. Advanced Organic Chemistry: Part B: Reaction and Synthesis from Springer serves as a rigorous deep dive for anyone serious about mastering chemical transformations. Unlike introductory texts that gloss over the nuances of electron movement, this volume focuses heavily on the mechanics of how reactions actually unfold in a laboratory setting. It is an essential companion for researchers navigating the intricate pathways of organic synthesis. While the density of the material requires significant mental heavy lifting, the clarity of the Springer editorial approach ensures that the logic holds up under scrutiny. It is less of a casual read and more of a foundational tool for professional chemical mastery.

What We Like
Reaction mechanisms focus
Synthesis depth
Springer academic standard
Advanced chemical theory

Strategic Applications of Named Reactions in Organic Synthesis

Strategic Applications of Named Reactions by Academic Press

4.6 (156 ratings)
ACADEMIC PRESS 22116247 8.40 X 1.60 X 10.90 Inches 5.25 Pounds

Reviews for ACADEMIC PRESS (PM Score)

9.6 PM Score
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Amazon.com 9.68 Yes Yes Yes

A researcher stares at a complex molecular scaffold, searching for the precise mechanistic pathway to forge a critical carbon-carbon bond. This is exactly where Academic Press’s Strategic Applications of Named Reactions in Organic Synthesis becomes an indispensable companion at the laboratory bench. Instead of digging through disparate journal articles, you get a concentrated deep dive into the specific transformations that drive modern synthesis. It bridges the gap between theoretical mechanism and practical, tactical execution in the lab. For any chemist navigating the intricacies of total synthesis or method development, this text serves as a high-level roadmap for selecting the right reaction at the right time, making the daunting task of retrosynthetic analysis feel significantly more manageable.

What We Like
Organic synthesis focus
Named reaction strategies
Academic Press publication
Advanced chemical methodology

Organic Chemistry: 100 Must-know Mechanisms: In Organic Chemistry (De Gruyter Textbook)

De Gruyter Organic Chemistry 100 Must-Know Mechanisms

DE GRUYTER 33602187 6.60 X 0.70 X 9.30 Inches 0.95 Pounds

Reviews for DE GRUYTER (PM Score)

8.3 PM Score
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Amazon.com 9.68 Yes Yes Yes

Organic chemistry students often hit a wall when trying to move past rote memorization into true mechanistic understanding. This De Gruyter textbook serves as a vital bridge for that exact transition, focusing on the core movement of electrons that defines the discipline. Instead of wading through endless fluff, you get a curated collection of the most essential reactions you will encounter in advanced coursework or laboratory settings. It functions less like a standard, dense textbook and more like a strategic roadmap for mastering complex chemical transformations. Having these fundamental patterns organized in one place makes the daunting task of predicting reaction outcomes feel much more manageable and intuitive.

What We Like
Essential reaction patterns
Core mechanistic focus
Curated mechanism list
Academic textbook format
#5

The Art of Writing Reasonable Organic Reaction Mechanisms

The Art of Writing Reasonable Organic Reaction Mechanisms

4.6 (55 ratings)
6.10 X 1.08 X 9.25 Inches 1.53 Pounds

Reviews for (PM Score)

7.4 PM Score
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SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Ibook USA 9.93 Yes Yes Yes

Can a single textbook actually bridge the gap between memorizing formulas and truly understanding chemical transformations? The Art of Writing Reasonable Organic Reaction Mechanisms tackles this exact problem by shifting the focus from rote repetition to logical deduction. Instead of just showing you the final product, this guide walks you through the underlying reasoning required to map out how electrons move during a reaction. It feels less like a dry academic manual and more like a mentor guiding you through the nuances of molecular behavior. For any student or researcher struggling to visualize complex pathways, this resource provides the structural framework needed to build confidence in organic chemistry. It is a focused, essential tool for anyone serious about mastering the logic of chemical reactivity.

What We Like
Logic-based approach
Reaction pathway guidance
Mechanism mastery
Organic chemistry focus
#6

March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure

Wiley March's Advanced Organic Chemistry Textbook

WILEY 36058539 7.30 X 3.50 X 10.10 Inches 7.50 Pounds

Reviews for WILEY (PM Score)

6.1 PM Score
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Amazon.com 9.68 Yes Yes Yes

The dense, authoritative weight of this textbook immediately signals that you are holding a cornerstone of chemical literature. March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure is not a casual read. It is a rigorous deep dive into the very mechanics that govern molecular behavior. As a professional resource from Wiley, it moves far beyond introductory concepts to explore the complex nuances of reaction pathways and structural intricacies. While the price point reflects its status as a specialized academic investment, the depth of insight provided makes it an indispensable asset for serious researchers and advanced students. If you are looking to master the fundamental logic behind organic transformations, this volume serves as a definitive roadmap through the complexities of the field.

What We Like
Advanced chemical mechanisms
Reaction structure analysis
Rigorous academic content
Wiley professional edition
#7

Arrow-Pushing in Organic Chemistry: An Easy Approach to Understanding Reaction Mechanisms

Wiley-Interscience Arrow-Pushing in Organic Chemistry Guide

WILEY-INTERSCIENCE 7.10 X 0.70 X 10.00 Inches 1.25 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Super Book Sales 9.86 No No No

Organic chemistry textbooks often feel like impenetrable walls of text, but this Wiley-Interscience guide treats reaction mechanisms like a logical puzzle rather than a memorization marathon. Instead of forcing you to swallow massive amounts of data, it focuses on the fundamental logic of electron movement. I found that the 'easy approach' promised in the title actually delivers on simplifying the intimidating process of arrow-pushing. It bridges the gap between seeing a complex structure and actually understanding why those electrons move the way they do. For anyone struggling to visualize how bonds break and form, this resource provides a much-needed roadmap that turns abstract concepts into manageable, predictable patterns.

What We Like
Reaction mechanism focus
Simplified approach
Organic chemistry guide
Logic-based learning
#8

Writing Reaction Mechanisms in Organic Chemistry

Writing Reaction Mechanisms in Organic Chemistry Ebook

Reviews for (PM Score)

5.2 PM Score
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SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com Services LLC 0.00 No No No

Organic chemistry students looking to master the visual language of molecular transformations will find this digital guide indispensable. Mastering electron pushing and mechanistic pathways is often the steepest hurdle in a chemistry curriculum, and this ebook targets that specific pain point directly. Instead of wading through dense, generalized textbooks, you get a focused resource dedicated to the actual act of drawing and understanding reactions. It represents a specialized investment in your technical literacy. Since it is available for immediate download, you can integrate these lessons into your study sessions the moment you hit purchase, making it a highly efficient tool for anyone tackling advanced coursework.

What We Like
Digital ebook format
Immediate download access
Mechanistic focus
Organic chemistry specialty
#9

Organic Chemistry: Theory, Reactivity and Mechanisms in Modern Synthesis

Wiley-Interscience Organic Chemistry Theory and Synthesis Guide

WILEY-INTERSCIENCE 54603245 8.80 X 2.30 X 11.00 Inches 7.95 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

After weeks of intensive study sessions, it becomes clear that this Wiley-Interscience text is a cornerstone for anyone serious about mastering complex molecular transformations. Organic Chemistry: Theory, Reactivity and Mechanisms in Modern Synthesis doesn't just skim the surface. It dives deep into the fundamental logic that governs how molecules interact. I found the progression from basic theory to advanced mechanistic pathways to be incredibly logical, making it an essential companion for advanced students or professional researchers. While the depth of the material requires significant mental heavy lifting, the clarity of the synthesis explanations provides a much-needed roadmap through the intricacies of modern chemical reactions. It is a substantial investment in your scientific education that pays off in sheer conceptual clarity.

What We Like
Advanced mechanistic insights
Modern synthesis focus
Comprehensive theoretical framework
Professional academic resource
#10

Things I Learned In Organic Chemistry Interesting Reactions Nomenclature Deadly Compounds How To Draw Hexagons: Nice Notebook For Chemistry Students

Organic Chemistry Student Notebook with Reaction Guides

INDEPENDENTLY PUBLISHED 6.00 X 0.30 X 9.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Most chemistry students settle for blank, uninspired notebooks that offer zero context during late-night study sessions. This specialized notebook changes the game by integrating essential organic chemistry concepts directly into your note-taking experience. Instead of just providing empty pages, it touches on the core pillars of the discipline, from complex nomenclature and interesting reactions to the dreaded task of drawing perfect hexagons. It serves as a practical companion for anyone navigating deadly compounds or trying to master structural formulas. At a very accessible price point, it acts as both a workspace and a quick-reference guide, making the daunting world of organic chemistry feel significantly more manageable and organized.

What We Like
Reaction guides included
Nomenclature support
Hexagon drawing practice
Chemistry student focused

Introduction to Phase Equilibria in Ceramic Systems

Introduction to Phase Equilibria in Ceramic Systems Ebook

Reviews for (PM Score)

4.2 PM Score
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SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com Services LLC 0.00 No No No

Introduction to Phase Equilibria in Ceramic Systems stands as an essential cornerstone for materials science students and professional ceramic engineers. This digital ebook provides a deep dive into the complex thermodynamic principles that govern how ceramic materials behave under varying conditions. Because it is available for immediate download, you can bypass the wait for physical shipping and dive straight into the technical complexities of phase diagrams and equilibrium states. It serves as a specialized academic investment that targets a very specific niche of thermal and chemical stability research. It is a streamlined, focused resource that prioritizes high-level technical accuracy over broad, superficial overviews.

What We Like
Instant digital download
Ceramic system focus
Phase equilibria expertise
Academic technical resource
#12

Reaction Mechanisms in Environmental Organic Chemistry

Reaction Mechanisms in Environmental Organic Chemistry by CRC Press

CRC PRESS 8.25 X 1.00 X 9.75 Inches 2.18 Pounds

Reviews for CRC PRESS (PM Score)

4.1 PM Score
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  • Used Book in Good Condition
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Teknik-books 6.44 No No No

This CRC Press textbook serves as a vital cornerstone for anyone diving into the complexities of environmental organic chemistry, and it remains a highly reliable resource for academic study. Since this is a used copy in good condition, you are getting a substantial piece of scientific literature without the heavy burden of a brand-new retail price. The text provides the deep mechanistic insights necessary for understanding how organic compounds behave in our ecosystems. It is an excellent find for students or researchers who need a solid, physical reference that has been well-maintained. It represents a practical way to acquire high-level specialized knowledge that is currently in stock and ready for immediate use in your laboratory or study sessions.

What We Like
Good used condition
In stock
Specialized scientific text
CRC Press publication
#13

Writing Reaction Mechanisms in Organic Chemistry

Writing Reaction Mechanisms in Organic Chemistry by Academic Press

ACADEMIC PRESS ILLUSTRATED 7.50 X 0.90 X 9.10 Inches 2.29 Pounds

Reviews for ACADEMIC PRESS (PM Score)

4.0 PM Score
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SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Organic chemistry students struggling to bridge the gap between theory and the actual drawing of electron movements need this text immediately. Mastering the logic behind curved arrows and molecular transformations is often the single biggest hurdle in advanced coursework, and this Academic Press guide tackles that specific pain point head-on. It functions less like a dry textbook and more like a specialized roadmap for navigating complex chemical pathways. Instead of just memorizing outcomes, you learn the fundamental language of how bonds break and form. At a price point, it is a serious investment in your academic foundation, but for anyone serious about pursuing a career in synthesis or medicinal chemistry, the clarity it provides is indispensable.

What We Like
Organic chemistry guide
Mechanism writing focus
Academic Press publication
Specialized technical text

Side Reactions in Organic Synthesis II: Aromatic Substitutions

Side Reactions in Organic Synthesis II: Aromatic Substitutions

Reviews for (PM Score)

3.1 PM Score
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SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
JOHN WILEY AND SONS INC 0.00 No No No

You are staring at a failed reaction yield in the lab, wondering exactly which unintended pathway diverted your aromatic substrate away from the desired product. This digital ebook serves as a specialized deep dive into those exact moments of frustration, focusing specifically on the complexities of aromatic substitutions. Rather than a broad overview, it targets the nuanced side reactions that can derail a synthesis, making it an essential reference for researchers navigating complex organic pathways. Because it is available for immediate download, you can pull up these technical insights on your tablet right at the lab bench. At eighty-three dollars, it functions less like a casual read and more like a precision tool for mastering the unpredictability of chemical transformations.

What We Like
Aromatic substitution focus
Digital download format
Advanced organic synthesis
Immediate access
#15

Free Radical Reactions in Preparative Organic Chemistry

Free Radical Reactions in Preparative Organic Chemistry

Reviews for (PM Score)

0.0 PM Score
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BookDept 6.17 No No No

This specialized organic chemistry text serves as a vital resource for researchers navigating the complexities of radical mechanisms in a laboratory setting. While many textbooks focus heavily on theoretical frameworks, this volume targets the practical application of these reactions within preparative organic chemistry. It is a focused, academic deep dive that avoids unnecessary fluff, making it a direct tool for those working in synthetic labs. It offers an accessible entry into a niche subject that is often buried in much more expensive, generalized chemistry encyclopedias. If you are looking for a streamlined guide to understanding how free radicals behave during actual chemical preparation, this book hits the mark without wasting your time.

What We Like
Preparative chemistry focus
Specialized organic text
Academic resource
Niche subject matter
Buying Guide

A Guide to Selecting the Best Reactions in Organic Chemistry Books

A Guide to Selecting the Best Reactions in Organic Chemistry Books

Determine Your Functional Depth: Mechanism vs. Methodology

The first decision factor is whether you need to understand why a reaction happens or how to perform it. For students and those entering graduate school, mechanistic books are paramount. These texts focus on electron pushing, transition states, and orbital interactions (FMO theory). You should look for books that prioritize the 'why'—explaining the influence of stereochemistry, solvent effects, and electronic induction on the reaction outcome. Conversely, if you are a synthetic chemist in a lab, you require methodology books. These are encyclopedic references that focus on reagents, yields, conditions, and substrate scope. A methodology book tells you which catalyst to use to achieve a specific transformation, while a mechanistic book tells you how that catalyst interacts with your starting material.

Assess the Level of Mechanistic Detail

Organic chemistry books generally fall into three pedagogical tiers. The first tier is 'Introductory/General,' which focuses on foundational reactions like nucleophilic substitution (SN1/SN2) and electrophilic addition. These are best for undergraduates. The second tier is 'Advanced/Mechanistic,' which delves into pericyclic reactions, organometallic cycles, and complex rearrangements. This is the gold standard for PhD candidates. The third tier is 'Specialized/Total Synthesis,' which applies reactions to the construction of complex natural products. When choosing, ensure the book's complexity matches your current cognitive load. A book that is too advanced will be a source of frustration, while one that is too basic will fail to provide the predictive tools needed for research.

Look for Visual and Structural Clarity

In organic chemistry, a picture is worth a thousand words. A high-quality reaction book must feature high-resolution, clear chemical structures. Pay close attention to how the book handles 3D representations. Does it use wedge-dash notation effectively to explain stereochemical outcomes? Are the reaction arrows (curved arrows) drawn with precision to show electron flow? Poorly formatted books can lead to fundamental misunderstandings of regioselectivity and stereoselectivity. Furthermore, check if the book includes 'reaction maps' or summary tables that allow you to quickly scan for specific functional group transformations.

Check for Modernity and Reagent Relevance

The field of organic chemistry evolves rapidly, particularly in the realms of transition-metal catalysis, photoredox catalysis, and green chemistry. A book written in the 1980s may be excellent for classical carbonyl chemistry but will be woefully inadequate for a modern researcher looking for cross-coupling techniques or C-H activation methods. When evaluating a text, look at the publication date or the bibliography. If the book does not mention modern catalytic cycles or sustainable synthetic methodologies, it may be better suited as a historical reference rather than a primary tool for contemporary laboratory work.

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Jump back to our ranked picks or compare the shortlist side by side.

Frequently Asked Questions

Quick answers about Reactions In Organic Chemistry Books before you buy.

While textbooks focus on fundamental mechanisms and theory, reaction books are specialized references that catalog specific transformations, functional group interconversions, and optimized synthetic protocols for laboratory use.

Most reaction books are designed for advanced undergraduates or graduate researchers. Beginners should stick to core textbooks first to master basic electron pushing before moving to specialized reaction encyclopedias.

Choose a mechanism book if you want to understand 'why' and 'how' electrons move. Choose a methodology book if you need to know 'which' reagents and conditions will successfully execute a specific transformation in a lab.

High-quality reaction books often include detailed experimental sections, including molar ratios, temperature requirements, and work-up steps, though some theoretical volumes focus solely on the electronic nature of the reaction.

Organic chemistry is an evolving field. While foundational reaction mechanisms rarely change, books focusing on catalysis or green chemistry should be updated more frequently to include modern, more efficient methodologies.

Yes, specialized reaction books are essential tools for retrosynthetic analysis, providing a library of known chemical transformations to help build complex molecular architectures.

Most reputable academic publishers use standardized IUPAC nomenclature and consistent arrow-pushing conventions, making them highly reliable for cross-referencing with peer-reviewed literature.
Research & Insights

Our Analysis of Reactions In Organic Chemistry Books

1,405 Reviews Analyzed
15 Products Evaluated
5.8 Avg PM Score
9 Brands Ranked

Top 10 Reactions In Organic Chemistry Books Brands on Amazon

Share of top-ranked products by brand, from our editorial analysis.

  1. 01 5 (33.3%)
  2. 02 Academic Press 2 (13.3%)
  3. 03 Wiley-Interscience 2 (13.3%)
  4. 04 Black Dog & Leventhal 1 (6.7%)
  5. 05 Crc Press 1 (6.7%)
  6. 06 De Gruyter 1 (6.7%)
  7. 07 Independently Published 1 (6.7%)
  8. 08 Springer 1 (6.7%)
  9. 09 Wiley 1 (6.7%)

What Our Analysis Found

We've carried out a comprehensive analysis of 1,405 reviews on Reactions In Organic Chemistry Books, using our selection criteria to identify the best options in the science & math. Our findings reveal that most customers typically select Reactions In Organic Chemistry Books priced around $70.86, with top brands including academic press, wiley, crc press, independently published, black dog & leventhal, de gruyter and wiley-interscience and springer.

Our team of expert editors reviewed these high-quality items and handpicked the top 15 Reactions In Organic Chemistry Books for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the science & math category — including amazon.com, superbookdeals-, amazon.com services llc, teknik-books, bookdept, super book sales and john wiley and sons inc and ibook usa.

We are dedicated to assisting our users in finding the right asins Products based on their needs, saving them considerable time when choosing which Reactions In Organic Chemistry Books to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.

Side by Side

Comparison Table

Compare the top 15 picks at a glance — select a column to sort.

# Product Brand PM Score Rating Where to Buy
1 Reactions: An Illustrated Exploration of Elements by Black Dog & Leventhal Black Dog & Leventhal 9.8 4.8 (891) Buy on Amazon
2 Springer Advanced Organic Chemistry Part B Springer 9.7 4.7 (151) Buy on Amazon
3 Strategic Applications of Named Reactions by Academic Press Academic Press 9.6 4.6 (156) Buy on Amazon
4 De Gruyter Organic Chemistry 100 Must-Know Mechanisms de Gruyter 8.3 4.3 (80) Buy on Amazon
5 The Art of Writing Reasonable Organic Reaction Mechanisms 7.4 4.6 (55) Buy on Amazon
6 Wiley March's Advanced Organic Chemistry Textbook Wiley 6.1 4.9 (23) Buy on Amazon
7 Wiley-Interscience Arrow-Pushing in Organic Chemistry Guide Wiley-Interscience 5.3 4.3 (19) Buy on Amazon
8 Writing Reaction Mechanisms in Organic Chemistry Ebook 5.2 4.8 (8) Buy on Amazon
9 Wiley-Interscience Organic Chemistry Theory and Synthesis Guide Wiley-Interscience 5.2 4.7 (9) Buy on Amazon
10 Organic Chemistry Student Notebook with Reaction Guides Independently Published 5.1 5.0 (1) Buy on Amazon
11 Introduction to Phase Equilibria in Ceramic Systems Ebook 4.2 3.9 (6) Buy on Amazon
12 Reaction Mechanisms in Environmental Organic Chemistry by CRC Press CRC Press 4.1 4.0 (1) Buy on Amazon
13 Writing Reaction Mechanisms in Organic Chemistry by Academic Press Academic Press 4.0 3.8 (4) Buy on Amazon
14 Side Reactions in Organic Synthesis II: Aromatic Substitutions 3.1 3.0 (1) Buy on Amazon
15 Free Radical Reactions in Preparative Organic Chemistry 0.0 0.0 Buy on Amazon