Best 365 By Whole Foods Market Vitamin B Supplements in 2026

High-potency, fast-dissolving tablets featuring bioactive forms of both vitamin B12 (1000mcg methylcobalamin) and folate to support cardiovascular and nervous system health.*

Convenient lozenge form supports optimal absorption and utilization by the body.*

Folate complements actions of B12 for homocysteine methylation and nervous system function. These tiny tablets use premium active folate (methylfolate).*

High Potency, Active Complex - This activated B complex is formulated to enhance your lifestyle with amounts and forms of B vitamins that are directly usable by the human body.*

Superior Folate & B12 - Includes Metafolin (L-5-MTHF), a bioactive form of folate that ensures more immediate effects on metabolism than common folic acid. B12 as methylcobalamin promotes B12 absorption and bioavailability.*

B Vitamins At Their Best - Includes benfotiamine, a fat-soluble derivative of thiamin with increased absorption compared to common water-soluble forms. Also includes active forms of vitamin B2 and vitamin B6 as P-5-P, nutrients that support energy production (metabolism).*

For optimal assimilation and pH balance, this formulation uses zinc citrate, the natural form of zinc that is found in human milk.

Vitamin B6 and ascorbic acid have also been added to facilitate zinc metabolism.

Zinc is an essential mineral that activates more than 70 enzymes, including those that assist with protein synthesis and tissue repair.*

This high-potency B-complex vitamin supplement is formulated to be hypoallergenic* and yeast free.

B vitamins are essential nutrients required for optimal health and functioning of numerous systems and biochemical reactions in the body, including energy production, brain, liver and nerve cell function, and muscle tone in the GI tract.*

Active forms of folate (Metafolin® L-5-methyltetrahydrofolate) and vitamin B12 (methylcobalamin) are used for enhanced absorption and bioavailability.*

A unique formula that combines bioactive forms of four essential B vitamins with trimethylglycine (betaine).*

Vitamins B2, B6, B12, and folate are provided in active, coenzyme forms for maximal bioavailability and function.*

These ingredients work together to synergistically support methylation processes and help maintain normal homocysteine metabolism.*

Supplies methylcobalamin, the active, coenzyme form of vitamin B12.

Prepared as a convenient liquid to support rapid and efficient absorption of this important B vitamin.*

1 mg (1000 mcg) of vitamin B12 per dropper full.

Make It Two - This maintenance multivitamin offers an ideal middle ground between once-dailies (which may provide insignificant nutrient amounts) and comprehensive 6-tablet formulas. Supplies significant amounts of essential nutrients in well-utilized forms in just two tablets daily.*

Professional Grade, Premium Nutrients - Packed with high quality, bioavailable nutrients designed for optimal absorption and tolerance. Compared to common retail once daily multis, VitaPrime offers enhanced antioxidant protection, broader trace element nutrition, and augmented B vitamin support.*

Active B Vitamins & Mineral Chelates - Active folate (L-5-MTHF), chelated minerals (magnesium bisglycinate chelate & more!), and B12 as methylcobalamin support optimal comfort and efficacy of these essential nutrients.*

Make It Two - This maintenance multivitamin offers an ideal middle ground between once-dailies (which may provide insignificant nutrient amounts) and comprehensive 6-capsule formulas. Supplies significant amounts of essential nutrients in well-utilized forms in just two capsules daily.*

Professional Grade, Premium Nutrients - Packed with high quality, bioavailable nutrients designed for optimal absorption and tolerance. Compared to common retail once daily multis, VitaPrime offers enhanced antioxidant protection, broader trace element nutrition, and augmented B vitamin support.*

Active B Vitamins & Mineral Chelates - Active folate (L-5-MTHF), chelated minerals (magnesium bisglycinate chelate & more!), and B12 as methylcobalamin support optimal comfort and efficacy of these essential nutrients.*

Designed to support the body's ability to respond to stress.*

Delivers beneficial amounts of glycyrrhizic acid, herbs, and several vitamins.

Featuring vitamin B6 (as pyridoxal-5-phosphate), n-acetyl tyrosine, L-carnitine, eleuthero, rhodiola, bacopa, and more. Please note that this is not a vegetarian formula.

Supports adrenal function with botanicals recognized to have adaptogenic properties.*

Eleuthero and rhodiola act on neurotransmitter function, the central nervous system, and cardiovascular function to help the body adjust appropriately when faced with biological, physical, or chemical challenges.*

Cordyceps mushroom, known for its revitalizing effects, and pantothenic acid, a B vitamin required for adrenal hormone formation, are also included.*