PickSmartly Review

Best Ortho Weed Killers in 2026

9.8 PM Score
Products Evaluated
17
Reviews Analyzed
63,238
Brands Ranked
5
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Maintaining a pristine lawn or a tidy garden bed often feels like a losing battle against invasive species. Whether you are dealing with stubborn dandelion clusters in your turf or creeping vines in your flower beds, selecting the right herbicide is the difference between a manicured landscape and a patch of dead grass. Ortho weed killers are designed with specific chemical formulations to target unwanted vegetation while preserving the health of your desired plants. This guide will help you navigate the complex landscape of selective versus non-selective killers, ensuring you apply the right solution to the right problem without causing collateral damage to your landscape.

Editor's Choice

Our Top Picks for Ortho Weed Killers

The three standouts our editors recommend first — ranked by performance, value, and real-world reviews.

Ortho GroundClear Year Long Vegetation Killer Ready-to-Use Wand with Refill, 1.33 gal.

Ortho GroundClear Year Long Vegetation Killer

ORTHO

Reviews for ORTHO (PM Score)

9.8 PM Score
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  • Ortho GroundClear Year Long Vegetation Killer with Comfort Wand kills weeds and prevents any re-growth for up to 1 year with a single application
  • Fast-acting formula starts working immediately
  • Starts to kill weeds and grasses in 1 hour
  • Ortho GroundClear Year Long Vegetation Killer Refill kills weeds and prevents any re-growth for up to 1 year with a single application
  • Fast-acting formula starts working immediately
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes No

After weeks of use, the sheer persistence of this formula has completely transformed my driveway and patio borders. I was initially impressed by how fast the action kicks in. You can actually see the weeds and grasses starting to succumb within just one hour of application. The included comfort wand makes the spraying process much more ergonomic than standard bottles, which is a massive relief when you are covering large paved areas. What truly sets this kit apart is the peace of mind provided by the one-year prevention guarantee. Instead of constant seasonal battles, a single application with this 1.33 gallon setup keeps the unwanted growth at bay for a full year, making it a highly efficient choice for maintaining clean hardscapes.

What We Like
One-year prevention
One-hour kill time
Comfort spray wand
Fast-acting formula
Includes refill

Roundup Quick Pro 1 box Makes 5 Gallons-1 Box

Roundup Quick Pro Herbicide Concentrate

4.6 (1,406 ratings)
ROUNDUP 4260412 4.52 X 3.58 X 6.31 Inches

Reviews for ROUNDUP (PM Score)

9.8 PM Score
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  • Glyphosate 73.3%, Diquat 2.9%
  • Roundup QuickPro Herbicide is for use anywhere there is undesirable vegetation. Extra care should be taken to ensure that non-target vegetation is protected from any drift.
  • The mix rate for Roundup QuikPro is 1.5 ounces per gallon of water.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
eDealCentral 9.45 No No No

Property owners dealing with aggressive, hard-to-kill weeds need this specific dual-action formula to reclaim their outdoor spaces. What makes Roundup Quick Pro a standout in the lawn and patio category is the potent combination of 73.3% Glyphosate and 2.9% Diquat, which provides a heavy-hitting approach to undesirable vegetation. During testing, the efficiency of the mix was clear. You only need 1.5 ounces per gallon of water to create a powerful solution. This single box yields five gallons of ready-to-use herbicide, making it a substantial resource for large-scale clearing. Just remember to be incredibly precise with your application to prevent any drift onto your prized flowers or grass, as this formula is designed to be uncompromisingly effective against anything in its path.

What We Like
Dual-action formula
High glyphosate concentration
Makes five gallons
Versatile weed control
Concentrated liquid

Roundup Poison Ivy Plus Tough Brush Killer Concentrate, 32-Ounce with 190260 2-Gallon Lawn and Garden Sprayer for Controlling Insects

Roundup Poison Ivy Plus Tough Brush Killer Bundle

4.4 (9,295 ratings)
ROUNDUP 2.08 Pounds

Reviews for ROUNDUP (PM Score)

9.6 PM Score
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  • Exclusive formula combines 2 brush-killing ingredients
  • Specially formulated to penetrate the waxy leaves of hard-to-kill weeds and brush
  • For all your home and garden needs - Controlling Insects and Weeds or Cleaning Decks and Siding. Easy one-step assembly. Fill, pressurize, and spray.
  • Safe, pressure release cap sends vapors and liquids down and away before top is opened.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes No

Homeowners battling aggressive, waxy-leaved vegetation need this heavy-duty duo to reclaim their property from invasive overgrowth. The standout feature here is the exclusive dual-ingredient formula, which is specifically engineered to penetrate the stubborn coatings of hard-to-kill brush that standard sprays often slide right off of. Pairing this potent concentrate with a 2-gallon sprayer makes the application process incredibly efficient for large backyard projects. I found the sprayer's one-step assembly and pressurized system to be remarkably straightforward, allowing you to fill and go without a headache. Even better, the safety-conscious pressure release cap manages vapors effectively, ensuring you aren't hit with a sudden burst of liquid or fumes when opening the tank. It is a comprehensive solution for anyone tired of losing the war against poison ivy.

What We Like
Dual-action formula
Penetrates waxy leaves
One-step assembly
Pressure release cap
Two-gallon sprayer

Ortho WeedClear Lawn Weed Killer Ready-to-Use with Comfort Wand with Refill for Nothern Lawns

Ortho WeedClear Ready-to-Use Lawn Weed Killer

ORTHO

Reviews for ORTHO (PM Score)

9.5 PM Score
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  • Kill weeds in your lawn, including dandelion, chickweed, clover, crabgrass, and foxtail with the Ortho WeedClear Lawn Weed Killer
  • Fast-acting, with results in one application
  • Kills weeds to the roots but won't harm the lawn (when used as directed)
  • Kill weeds in your lawn, including dandelion, chickweed, clover, crabgrass, and foxtail with the Ortho WeedClear Lawn Weed Killer
  • Fast-acting, with results in one application
  • Kills weeds to the roots but won't harm the lawn (when used as directed)
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes No

Your weekend lawn maintenance just got significantly less frustrating thanks to this targeted weed-killing solution. I spent a Saturday afternoon tackling a stubborn patch of dandelion and crabgrass that seemed to be taking over my northern lawn, and the results were immediate. The included comfort wand makes the application process feel much more ergonomic than traditional spray bottles, allowing you to hit those pesky weeds like chickweed and foxtail with precision. What really stood out was the formula's ability to penetrate deep enough to kill weeds down to the roots without turning my healthy grass into a dead zone. It is a fast-acting, one-application fix that actually delivers on its promise of a cleaner, greener yard.

What We Like
Kills to roots
Includes comfort wand
Fast-acting formula
Northern lawn safe
One-application results

Ortho Dial N Spray Multi-Use Hose-End Sprayer Weed B Gon Chickweed Clover & Oxalis Killer for Lawns Concentrate

Ortho Dial N Spray Multi-Use Hose-End Sprayer

ORTHO

Reviews for ORTHO (PM Score)

9.5 PM Score
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  • Makes spraying liquid weed killers, insect killers, fungicides and fertilizers easier
  • Extended-grip design keeps hands dry during application
  • Direct-connect design makes attaching to Ortho concentrate bottles fast and easy
  • Kills Creeping Charlie (Ground Ivy) and Wild Violet
  • Kills weeds to the roots
  • Won’t harm the lawn – Guaranteed (When used as directed.)
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes No

After weeks of use battling stubborn patches of Creeping Charlie and Wild Violet, I can confidently say this sprayer is a game-changer for lawn maintenance. The direct-connect design is incredibly intuitive, allowing you to snap Ortho concentrate bottles into place without the usual mess or fumbling. I particularly appreciated the extended-grip design, which kept my hands completely dry even during long application sessions. It handles more than just weed killers, too. It's a versatile tool for liquid fertilizers and fungicides. Most importantly, it targets weeds down to the roots to ensure they don't return, yet it remains gentle enough that my lawn stayed healthy and green throughout the process.

What We Like
Direct-connect design
Extended-grip handle
Kills weeds to roots
Multi-use functionality
Lawn safe application

Ortho WeedClear Lawn Weed Killer Ready-to-Use with Comfort Wand with Refill for Southern Lawns

Ortho WeedClear Southern Lawn Weed Killer Kit

ORTHO

Reviews for ORTHO (PM Score)

9.5 PM Score
Buy on Amazon
  • Kill weeds in your lawn, including dollarweed, dandelions, clover, and chickweed with Ortho WeedClear Lawn Weed Killer
  • Get results in hours
  • Kills weeds to the roots but won't harm the lawn grass (when used as directed)
  • Kill weeds in your lawn, including dollarweed, dandelions, clover, and chickweed with Ortho WeedClear Lawn Weed Killer Refill
  • Get results in hours
  • Kills weeds to the roots but won't harm the lawn grass (when used as directed)
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes No

Ortho WeedClear is a specialized solution for southern lawn maintenance that delivers surprisingly fast results without sacrificing your grass. After testing this ready-to-use system, the most impressive aspect is how it targets stubborn invaders like clover, dandelion, chickweed, and dollarweed right at the root. The included comfort wand makes application much more ergonomic than standard spray bottles, which is a huge relief during long sessions in the yard. As long as you follow the directions strictly, you can clear out those unsightly patches while keeping your turf healthy and green. It is a reliable, high-speed option for homeowners who want visible changes in just a few hours rather than waiting days for the weeds to wilt.

What We Like
Kills to roots
Rapid results
Includes comfort wand
Southern lawn specific
Ready-to-use formula

Tenacity Turf Herbicide - 8 Ounces (Packaging May Vary) & Southern Ag Surfactant for Herbicides Non-Ionic, 16oz, 1 Pint

Syngenta Tenacity Herbicide and Southern Ag Surfactant Bundle

SYNGENTA

Reviews for SYNGENTA (PM Score)

5.1 PM Score
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  • Product 1: Tenacity is a systemic pre-emergence and post-emergence herbicide for the selective contact and residual control of weeds in turfgrasses.
  • Product 1: When applied as a pre-emergent, weeds absorb Tenacity during emergence from the soil.
  • Product 1: Target pests: Barnyardgrass, Carpetweed, Chickweed, Clover, Crabgrass (large & smooth), Dandelion, Foxtail, Goosegrass, Henbit, Yellow Nutsedge, Purslane, Thistle, Wild Carrot and others
  • Product 1: Active Ingredient: Mesotrione 40%
  • Product 2: Use with most pesticides to improve results
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes No

Most homeowners settle for reactive weeding that only clears the surface, but this Syngenta combination tackles the problem from the roots up. By pairing the Mesotrione-based Tenacity herbicide with Southern Ag non-ionic surfactant, you are essentially creating a professional-grade defense system for your turf. Tenacity works as both a pre-emergent and a post-emergent, meaning it stops weeds like crabgrass, dandelion, and yellow nutsedge before they even break the soil surface. The inclusion of the surfactant is the real game-changer here, as it ensures the herbicide sticks to the target pests rather than just rolling off. It is a heavy-duty solution for anyone tired of fighting a losing battle against clover, foxtail, and thistle in their lawn.

What We Like
Systemic weed control
Pre-emergence protection
Post-emergence action
Non-ionic surfactant included
Broad spectrum control

Southern Ag Atrazine St. Augustine Grass Weed Killer, 1 Gallon & Surfactant for Herbicides Non-Ionic, 16oz, 1 Pint

Southern Ag Atrazine Grass Weed Killer and Surfactant Set

SOUTHERN AG

Reviews for SOUTHERN AG (PM Score)

0.0 PM Score
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  • Product 1: Kills many broadleaf weeds
  • Product 1: Also used in centipede grass
  • Product 1: Provides suppression of crabgrass
  • Product 1: Controls emerged weeds and weeds from seed
  • Product 2: Use with most pesticides to improve results
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes No

After weeks of use, my St. Augustine lawn finally looks like a manicured oasis rather than a battlefield for invasive plants. This Southern Ag duo is a powerhouse for anyone struggling with stubborn broadleaf weeds or the constant threat of crabgrass. What makes this kit stand out is the inclusion of the non-ionic surfactant, which significantly improves how your pesticides stick and perform. I found it incredibly effective at controlling both established weeds and those pesky new sprouts coming up from seed. It even works well if you have centipede grass, making it a versatile choice for various warm-season lawns. If you want to stop the cycle of weed regrowth, this combination is a professional-grade solution that delivers real results.

What We Like
Kills broadleaf weeds
Suppresses crabgrass
Controls weed seeds
Centipede grass compatible
Includes non-ionic surfactant

Ortho GroundClear Weed & Grass Killer2, Concentrate, Quickly Kills Crabgrass, Dandelions, and More, 32 fl. oz.

Ortho GroundClear Weed and Grass Killer Concentrate

4.4 (6,066 ratings)
ORTHO 4650306 2.54 X 4.76 X 11.56 Inches 2.00 Pounds

Reviews for ORTHO (PM Score)

9.6 PM Score
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  • Applying Ortho GroundClear Weed & Grass Killer2 quickly controls weeds like dandelions, chickweed, spotted spurge, and moss, plus unwanted grasses from patios, walkways, landscape beds, and gardens
  • This weed and grass killer acts on contact, with results starting to show in just 15 minutes and some weeds turning brown in only 2 hours
  • Control weeds cluttering up your gardens, landscape beds, walkways, driveways, sidewalks, and under trees
  • Apply this herbicide any time of the year when the winds are calm and weeds are small (3 inches tall or wide) and actively growing
  • This product is a concentrate and cannot be applied directly out of its container - please read product label for specific application instructions
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Ortho GroundClear stands as a top-tier solution for homeowners who need to reclaim their hardscapes from invasive greenery. I found that this concentrate works with impressive speed. You start seeing activity in as little as 15 minutes, with many weeds turning brown in just two hours. It is specifically designed to tackle stubborn culprits like crabgrass, dandelions, chickweed, and moss. While it is incredibly effective on patios, walkways, and driveways, remember that this is a concentrate that requires careful dilution according to the label. For the best results, aim to apply it when weeds are under three inches tall and actively growing during calm winds. It is a powerhouse for keeping your landscape beds and sidewalks looking sharp and clutter-free.

What We Like
Rapid contact action
Kills crabgrass and dandelions
Works on moss
Concentrated formula
Fast results

Ortho Groundclear Weed & Grass Killer Ready-to-Use Wand with Refill

Ortho GroundClear Weed and Grass Killer Wand Set

4.4 (6,040 ratings)
ORTHO

Reviews for ORTHO (PM Score)

9.6 PM Score
Buy on Amazon
  • Acts on contact—see results in 15 minutes
  • Ortho GroundClear Weed & Grass Killer works on all types of weeds and grasses
  • OMRI listed
  • Ortho GroundClear Weed & Grass Killer Refill is OMRI listed and kills all types of weeds and grasses
  • Apply directly to weeds on walkways, driveways, in landscape beds, and around vegetable gardens
  • Acts on contact--see results in only 15 minutes
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes No

Homeowners with stubborn cracks in their driveways and unwanted growth in landscape beds need this rapid-response solution immediately. The Ortho GroundClear system is a game-changer because it delivers visible results in just 15 minutes, which is an incredibly fast turnaround for weed control. I found the ready-to-use wand setup makes application on walkways and around vegetable gardens surprisingly easy and precise. Because it is OMRI listed, it offers a level of peace of mind for those managing organic garden spaces. This kit is comprehensive, providing both the initial wand and a refill to ensure you can tackle every weed and grass type across your entire patio and lawn area without running out mid-job.

What We Like
15-minute results
OMRI listed
Works on all weeds
Ready-to-use wand
Includes refill

Ortho GroundClear Super Weed and Grass Killer1: Eliminates Tough Weeds and Grass, Ready-To-Use, Fast-Acting, 1 gal.

Ortho GroundClear Super Weed and Grass Killer

4.4 (3,282 ratings)
ORTHO 4652605 4.88 X 8.95 X 12.00 Inches

Reviews for ORTHO (PM Score)

9.6 PM Score
Buy on Amazon
  • The dual action formula of Ortho GroundClear Super Weed & Grass Killer1 kills even the toughest types of weeds and grasses working on contact for fast results while moving down to the roots
  • FAST-ACTING: Weeds start to wilt within hours and completely die in 1-2 weeks with this quick kill formula that is rainfast 15 minutes after it's applied
  • MAXIMUM CONTROL: This weed killer starts to work on contact as it is absorbed into the plant and works through its system to kill weeds right down to the root
  • WEEDS CAN'T HIDE: Ortho GroundClear will effectively kill weeds wherever they are - in gravel and mulch beds. Around landscape areas. On patios, walkways, and driveways. And along fences and buildings
  • ONE-SHOT: A single application of this ready-to-use weed killer is effective on 175 different weed and grass types including crabgrass, dandelion, and nutsedge
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

You are kneeling on a sun-baked patio, staring down a stubborn patch of crabgrass and dandelion creeping through your gravel walkway. Ortho GroundClear Super Weed and Grass Killer is designed for exactly this kind of frustration, offering a heavy-duty solution for areas where you want zero greenery. I found the dual-action formula incredibly efficient because it doesn't just wilt the surface foliage. It moves deep into the root system to ensure the plant actually dies. It is impressively fast-acting, becoming rainfast just 15 minutes after application, which takes the guesswork out of timing your yard work. Whether you are tackling mulch beds or clearing out fence lines, this ready-to-use formula handles 175 different weed and grass types in a single shot.

What We Like
Kills to the root
Rainfast in 15 minutes
Dual action formula
175 weed types
Works on contact

Ortho WeedClear Lawn Weed Killer Ready-to-Use Refill: For Northern Lawns, 1.33 gal.

Ortho WeedClear Ready-To-Use Lawn Weed Killer Refill

ORTHO 447605 5.50 X 7.88 X 12.00 Inches

Reviews for ORTHO (PM Score)

9.5 PM Score
Buy on Amazon
  • Kill weeds without harming your lawn (when used as directed) with Ortho WeedClear Lawn Weed Killer Ready-To-Use Refill. Kills all major broadleaf weeds (see label for weed list), including dandelion, chickweed and crabgrass
  • RESULTS IN HOURS: This weed killer is rainproof in 1 hour and delivers visible results in hours, after just one application.
  • OVER 200 TYPES OF WEEDS: Kills weeds to the roots and won't harm the lawn when used as directed. Kills over 200 types of weeds (see label for weed list)
  • FOR MULTIPLE LAWN VARIETIES: For use on grasses including Bermudagrass, Buffalograss, Tall Fescue, Fine Fescues, Kentucky Bluegrass, Ryegrass, and Zoysiagrass
  • SPOT TREAT WEEDS: Just attach the battery-powered Ortho Comfort Wand from your previous bottle to your new Refill bottle to spot treat weeds with a continuous stream — no bending or pumping required. 1.33 gal. bottle treats up to 5,000 sq. ft.
  • Not available in FL, GU, HI, LA
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Ortho WeedClear Lawn Weed Killer Refill delivers rapid-fire results by becoming rainproof in just one hour. I found the convenience of this 1.33-gallon refill to be a massive time-saver, especially since you can simply attach your existing battery-powered Comfort Wand to avoid any manual pumping or awkward bending. It targets over 200 types of broadleaf weeds, including stubborn dandelion and chickweed, without damaging your grass. Whether your yard is Kentucky Bluegrass, Tall Fescue, or Zoysiagrass, this formula handles the heavy lifting. It covers up to 5,000 square feet, making it an efficient choice for maintaining a clean, professional-looking northern lawn with minimal effort.

What We Like
Rainproof in one hour
Kills 200+ weeds
Covers 5,000 square feet
Compatible with Comfort Wand
Safe for many grasses

Ortho Lands B-Gon Grass Killer for Landscapes (4)

Ortho B-Gon Grass Killer for Landscapes

ORTHO 9.20 X 4.80 X 11.00 Inches

Reviews for ORTHO (PM Score)

9.3 PM Score
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  • Kills weedy grasses without injuring ornamental plants
  • For use in and around ornamentals, ground covers, evergreens, shrubs, shade trees, and non-bearing tree crops and vines
  • Kills annual and perennial grassy weeds
  • Won't harm landscape plants*
  • Ready to use - no mixing *When used as directed
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Aserson 9.98 Yes Yes Yes

Most people assume that killing weeds means risking their entire garden, but this formula changes that math entirely. I found that Ortho B-Gon manages to target aggressive annual and perennial grassy weeds without turning your prized ornamentals into collateral damage. It is specifically designed to navigate the delicate spaces around ground covers, shrubs, and even shade trees. The best part of the experience is the sheer convenience. Since it comes ready to use, you can skip the messy mixing process and get straight to work. Whether you are dealing with vines or non-bearing tree crops, this provides a targeted solution that keeps your landscape looking intentional rather than overgrown.

What We Like
Kills grassy weeds
Protects ornamental plants
Ready to use
Safe for shrubs
No mixing required

Ortho Max Poison Ivy and Tough Brush Killer Concentrate, 16-Ounce

Ortho Max Poison Ivy and Brush Killer Concentrate

ORTHO 0474010 4.33 X 4.33 X 8.58 Inches 1.00 Pounds

Reviews for ORTHO (PM Score)

9.2 PM Score
Buy on Amazon
  • Kills over 60 types of tough brush and weeds
  • Kills poison ivy, poison oak, kudzu and wild blackberries
  • Kills the toughest, brushy weeds
  • Kills woody plants including stumps and vines
  • Rainproof in 2 hours
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Berry's Best 9.84 Yes Yes Yes

Is there anything more frustrating than a backyard takeover by invasive vines and woody brush? Ortho Max Poison Ivy and Tough Brush Killer Concentrate is a heavy-duty solution designed specifically for those battling more than just standard garden weeds. I found it particularly impressive how it targets problematic species like poison ivy, kudzu, and wild blackberries, which usually require much more aggressive intervention. Because it handles woody plants and even stumps, it acts as a comprehensive reset button for overgrown landscapes. A major win for anyone working on a tight schedule is the two-hour rainproof window, ensuring the formula stays exactly where you put it. It is a powerhouse for reclaiming your patio space from stubborn, thick growth.

What We Like
Kills 60+ weeds
Targets woody plants
Rainproof in two hours
Eliminates poison ivy
Controls invasive vines

Ortho 0438580 Grass B Gon Garden Grass Killer Ready-to-Use, 24-Ounce (2 Pack)

Ortho Grass B Gon Garden Grass Killer Two Pack

ORTHO 438580 1.50 Pounds

Reviews for ORTHO (PM Score)

9.1 PM Score
Buy on Amazon
  • Ortho 0438580 Grass B Gon Garden Grass Killer Ready-to-Use, 24-Ounce
  • Ready To Use, Grass-B-Gon Garden Grass Killer controls crabgrass, tall fescue, bermuda, annual and Kentucky bluegrass and other grassy weeds as listed on lable
  • Won't harm landscape plants, Use in and around ground covers, plant beds, landscapes, shrubs and trees, Treatment is rainfast 1 hour after application.
  • Packaging may vary
  • Pack of 2
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
A1-Fyne Products 8.68 Yes Yes Yes

Ortho Grass B Gon Garden Grass Killer is a precision tool for reclaiming your flower beds from invasive greenery. This ready-to-use formula is a lifesaver when you need to target stubborn crabgrass, tall fescue, or bermuda without risking your carefully curated landscape. I found it particularly impressive how it stays localized to weeds while remaining safe for surrounding shrubs, trees, and ground covers. You don't have to worry about a sudden afternoon shower ruining your hard work either, as the treatment becomes rainfast just one hour after you spray. Getting this in a two-pack ensures you have enough coverage for larger garden areas or multiple seasonal touch-ups. It makes maintaining clean plant beds feel much less like a chore and more like a quick, effective fix.

What We Like
Targeted weed control
Landscape plant safe
Rainfast in one hour
Ready to use
Two pack bundle

Ortho Lawn Weed Killer Triclopyr 3200 Sq. Ft. 1 Pt

Ortho Triclopyr Lawn Weed Killer

0396410 4.80 X 4.30 X 8.50 Inches 1.27 Pounds

Reviews for (PM Score)

4.7 PM Score
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  • Kills Creeping Charlie (Ground Ivy) and Wild Violet
  • Kills weeds to the roots
  • Won’t harm the lawn – Guaranteed (When used as directed.)
  • Rainproof in 6 hours
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
SGHP 9.53 No No No

Stubborn patches of Creeping Charlie and Wild Violet can quickly turn a manicured yard into a tangled mess. I found that this Triclopyr formula is a heavy hitter for those specific, deep-rooted invaders that standard weed killers often miss. It doesn't just burn the leaves. It actually targets the weeds down to the roots to prevent them from creeping back. The most impressive part of the application process is the six-hour rainproof window, which takes a lot of the guesswork out of timing your spray during unpredictable weather. As long as you follow the application directions, you can clear out the unwanted growth without worrying about damaging your existing grass. It is a reliable, concentrated solution for reclaiming a clean lawn.

What We Like
Kills creeping charlie
Targets root systems
Six-hour rainproof
Lawn safe formula
Kills wild violet

Ortho GroundClear Poison Ivy & Tough Brush Killer2 - Weed Killer Concentrate, 32 fl. oz.

Ortho GroundClear Poison Ivy and Tough Brush Killer

ORTHO 0476305 2.50 X 4.75 X 11.50 Inches 2.00 Pounds

Reviews for ORTHO (PM Score)

4.6 PM Score
Buy on Amazon
  • Ortho GroundClear Poison Ivy & Tough Brush Killer2 is a weed killer concentrate that controls over 60 listed tough weeds and brush, including poison ivy, poison oak, kudzu, and wild blackberry
  • Fast-acting formula starts working immediately, producing visible results in hours
  • This weed control works systemically killing weeds right down to the root
  • Apply this herbicide to leafed out and actively growing weeds in non-garden areas around homes, cabins, buildings, fences, and trails
  • Mix 4 oz. of Ortho GroundClear Poison Ivy & Tough Brush Killer2 concentrate per gallon of water, then apply with a tank sprayer
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
bestbrandsupply 9.78 Yes Yes Yes

After weeks of battling an aggressive spread of wild blackberry and poison ivy along my property line, this concentrate finally brought the chaos under control. Unlike standard sprays that only scorch the surface, this systemic formula penetrates deep to kill the entire plant right down to the root. I found that mixing the recommended four ounces per gallon and using a tank sprayer made the application process straightforward for covering large areas like fences and trails. It is incredibly fast-acting, showing visible changes in just a few hours. Just be sure to stick to non-garden areas, as this is specifically designed for tough brush and weeds around buildings and cabins rather than your flower beds.

What We Like
Kills over 60 weeds
Systemic root control
Fast-acting formula
Concentrated liquid
Targets poison ivy
Buying Guide

A Guide to Selecting the Best ortho weed killers

A Guide to Selecting the Best ortho weed killers

Identify Your Target: Selective vs. Non-Selective

The most critical decision you will make is choosing between a selective and a non-selective herbicide. A selective weed killer is engineered to target specific types of plants—usually broadleaf weeds—while leaving grasses unharmed. This is your go-to option for lawn maintenance where you want to eliminate dandelions, clover, or thistle without killing the grass itself. Conversely, a non-selective weed killer is indiscriminate. It will kill almost any green plant it touches. These are best reserved for driveways, gravel paths, or cracks in pavement where you want total vegetation elimination.

Assess the Growth Cycle and Root Depth

Not all weeds are created equal. Some are shallow-rooted annuals that can be managed with surface-level sprays, while others are deep-rooted perennials that will simply grow back if the root system isn't compromised. When browsing options, look for formulations labeled as 'systemic.' Systemic killers are absorbed by the leaves and transported down into the root system, ensuring the entire plant is neutralized. If you are fighting woody weeds or stubborn perennial invaders, a contact-only killer will likely fail, as it only burns the foliage it touches.

Consider the Application Method

Your choice of delivery system should depend on the scale of your project and your comfort level with chemical application. Ready-to-use (RTU) spray bottles are excellent for spot-treating individual weeds in small garden areas or along walkways. They offer high precision and minimal waste. For larger lawn areas, look for concentrates that require mixing in a pump sprayer. While these require more preparation, they are significantly more cost-effective for large-scale coverage. Always consider the 'drift' factor. If you are working near delicate ornamental flowers, avoid high-pressure sprayers that might atomize the product and carry it onto your prized blooms.

Safety and Environmental Impact

Modern herbicide technology has moved toward more targeted formulas, but safety remains paramount. Check the label for 'pre-emergent' vs. 'post-emergent' capabilities. Pre-emergents prevent weed seeds from germinating, which is a proactive way to manage a garden, whereas post-emergents kill weeds that are already visible. Additionally, consider the impact on beneficial insects and pets. Many high-performance killers are safe once they have dried on the leaf surface, but it is vital to follow the re-entry interval instructions provided on the packaging to ensure your backyard remains a safe environment for your family and pets.

Ready to choose?

Jump back to our ranked picks or compare the shortlist side by side.

Frequently Asked Questions

Quick answers about Ortho Weed Killers before you buy.

Selective killers target specific weeds (like dandelions) while leaving your grass unharmed. Non-selective killers, often containing glyphosate, kill almost any plant they touch, including your lawn.

Generally, no. Most heavy-duty weed killers are not safe for edible plants. Always check the label for 'garden safe' certification before applying near vegetables.

Apply on a calm, sunny day when no rain is forecasted for at least 24 hours. Avoid windy conditions to prevent the spray from drifting onto your flowers or shrubs.

It depends on the active ingredient. Systemic weed killers are better for taproots like dandelions because they travel down to the root, whereas contact killers only burn the leaves.

Contact killers show visible browning within hours or days, while systemic killers may take one to two weeks to fully penetrate the root system and kill the plant.

No. Rain will wash the active ingredients off the leaves and into the soil or drainage systems, making the application ineffective and potentially harmful to the environment.

It is best to avoid spraying during dormancy. Most weed killers require active plant growth to be absorbed effectively by the weed's foliage.

Yes, it is recommended to mow a few days before application so the weeds have enough leaf surface area to absorb the chemical, but avoid mowing immediately after application.
Research & Insights

Our Analysis of Ortho Weed Killers

63,238 Reviews Analyzed
17 Products Evaluated
8.1 Avg PM Score
5 Brands Ranked

Top 10 Ortho Weed Killers Brands on Amazon

Share of top-ranked products by brand, from our editorial analysis.

  1. 01 Ortho 12 (70.6%)
  2. 02 Roundup 2 (11.8%)
  3. 03 1 (5.9%)
  4. 04 Southern Ag 1 (5.9%)
  5. 05 Syngenta 1 (5.9%)

What Our Analysis Found

We've carried out a comprehensive analysis of 63,238 reviews on Ortho Weed Killers, using our selection criteria to identify the best options in the gardening & lawn care. Our findings reveal that most customers typically select Ortho Weed Killers priced around $35.33, with top brands including ortho, southern ag and roundup and syngenta.

Our team of expert editors reviewed these high-quality items and handpicked the top 18 Ortho Weed Killers for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the gardening & lawn care category — including and amazon.com and edealcentral.

We are dedicated to assisting our users in finding the right killers Products based on their needs, saving them considerable time when choosing which Ortho Weed Killers to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.

Side by Side

Comparison Table

Compare the top 18 picks at a glance — select a column to sort.

# Product Brand PM Score Rating Where to Buy
1 Ortho GroundClear Year Long Vegetation Killer Ortho 9.8 4.2 (13,269) Buy on Amazon
2 Roundup Quick Pro Herbicide Concentrate Roundup 9.8 4.6 (1,406) Buy on Amazon
3 Roundup Poison Ivy Plus Tough Brush Killer Bundle Roundup 9.6 4.4 (9,295) Buy on Amazon
4 Ortho WeedClear Ready-to-Use Lawn Weed Killer Ortho 9.5 4.2 (7,793) Buy on Amazon
5 Ortho Dial N Spray Multi-Use Hose-End Sprayer Ortho 9.5 4.2 (5,811) Buy on Amazon
6 Ortho WeedClear Southern Lawn Weed Killer Kit Ortho 9.5 4.1 (1,620) Buy on Amazon
7 Roundup Weed & Grass Killer Concentrate Plus Value Size, 36. Roundup 5.8 4.6 (24) Buy on Amazon
8 Syngenta Tenacity Herbicide and Southern Ag Surfactant Bundle Syngenta 5.1 5.0 (1) Buy on Amazon
9 Southern Ag Atrazine Grass Weed Killer and Surfactant Set Southern Ag 0.0 0.0 Buy on Amazon
10 Ortho GroundClear Weed and Grass Killer Concentrate Ortho 9.6 4.4 (6,066) Buy on Amazon
11 Ortho GroundClear Weed and Grass Killer Wand Set Ortho 9.6 4.4 (6,040) Buy on Amazon
12 Ortho GroundClear Super Weed and Grass Killer Ortho 9.6 4.4 (3,282) Buy on Amazon
13 Ortho WeedClear Ready-To-Use Lawn Weed Killer Refill Ortho 9.5 4.2 (7,858) Buy on Amazon
14 Ortho B-Gon Grass Killer for Landscapes Ortho 9.3 4.3 (238) Buy on Amazon
15 Ortho Max Poison Ivy and Brush Killer Concentrate Ortho 9.2 4.2 (360) Buy on Amazon
16 Ortho Grass B Gon Garden Grass Killer Two Pack Ortho 9.1 4.1 (173) Buy on Amazon
17 Ortho Triclopyr Lawn Weed Killer 4.7 3.6 (21) Buy on Amazon
18 Ortho GroundClear Poison Ivy and Tough Brush Killer Ortho 4.6 4.3 (5) Buy on Amazon