Best Alka Seltzer Antacids in 2026

Daisy
Last Updated: Jul 17, 2026

At a Glance: Our Top Picks for Alka Seltzer Antacids

TUMS Extra Strength Antacid Tablets for Chewable Heartburn Relief and Acid Indigestion Relief, Assorted Fruit Flavors - 330 Count
#TOP1
Tums Extra Strength Antacid Tablets For Chewable Heartburn
10.0
PM SCORE
TUMS Chewy Bites Antacid Tablets for Chewable Heartburn Relief and Acid Indigestion Relief, Assorted Berries - 60 Count
#TOP2
Tums Chewy Bites Antacid Tablets For Chewable Heartburn
9.9
PM SCORE
Amazon Basic Care Extra Strength Antacid SuperChews Assorted Fruit 90ct (Previously SoundHealth)
#TOP3
Amazon Basic Care Extra Strength Antacid Superchews Assorted
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Alka Seltzer Antacids of 2026

Market Overview
Alka Seltzer Antacids Reviewed
  • Reviews Analyzed: 131463 Items
  • PM Avg. Rating: 8.2 / 10
55 Products Evaluated
  • Highest Price: $118.79
  • Lowest Price: $2.16
  • Avg. Price: $18.61

Tums Extra Strength Antacid Tablets For Chewable Heartburn Relief And Acid Indigestion Relief, Assorted Fruit Flavors - 330 Count

TUMS
630721
2.40 X 4.00 X 8.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
KacKol Shopping 8.52

Features

Contents: 1 bottle containing 330 TUMS Extra Strength Antacid Tablets for Chewable Heartburn Relief and Acid Indigestion Relief in easy to take, delicious assorted fruit flavors (orange, cherry, lime and lemon) for immediate heartburn relief

Multi-Symptom Relief: This heartburn medicine treats the four signs of heartburn: burning in the chest, acid indigestion, sour stomach and upset stomach associated with these symptoms

Fast And Powerful Strength: Nothing works faster; These calcium carbonate tablets go to work instantly by starting to neutralize acid on contact

Gluten Free And Kosher: TUMS antacid tablets have the active ingredient 750 mg calcium carbonate

Number 1 Doctor Recommended: TUMS is the number 1 recommended adult antacid brand by doctors, pharmacists and OB-GYNs

Trusted Brand: America’s Number 1 antacid, providing trusted heartburn relief for 90 years, supported by a satisfaction guarantee

Tums Chewy Bites Antacid Tablets For Chewable Heartburn Relief And Acid Indigestion Relief, Assorted Berries - 60 Count

TUMS
491852
1.65 X 3.34 X 4.63 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Contents: 60 TUMS Chewy Bites Antacid Tablets for Chewable Heartburn Relief and Acid Indigestion Relief in assorted berry flavors (strawberry, mixed berry, raspberry) with a tasty outer shell and soft center in a portable, resealable bottle

Multi-Symptom Relief: This heartburn medicine treats the four signs of heartburn: burning in the chest, acid indigestion, sour stomach and upset stomach associated with these symptoms

Fast And Powerful Strength: Nothing works faster! These calcium carbonate tablets go to work instantly by starting to neutralize acid on contact

Gluten Free: This heartburn and sour stomach relief medicine has the active ingredient 750 mg calcium carbonate

Number 1 Doctor Recommended: TUMS is the number 1 recommended adult antacid brand by doctors, pharmacists and OB-GYNs

Trusted Brand: TUMS is America’s number 1 antacid, providing trusted heartburn relief for 90 years, supported by a satisfaction guarantee

Amazon Basic Care Extra Strength Antacid Superchews Assorted Fruit 90Ct (Previously Soundhealth)

AMAZON BASIC CARE
FETEGT230
2.63 X 2.63 X 4.75 Inches
0.72 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Chewy Not Chalky: Fast-acting relief for heartburn, acid indigestion, upset and sour stomach from 750 mg of calcium carbonate in an enjoyable product form

Full of Flavor: Delicious lemon, orange, and strawberry flavors are easily accessible in an easy-to-open flip cap bottle. Adults and children 12 years and up can take 1-2 chewable tablets every 2-4 hours as needed.

Same Benefits, Lower Cost: Amazon Basic Care Antacid Fruit Chews are formulated to include the same active ingredients and provide the same relief as the name brand, but at a lower price to consumers

This product was previously a SoundHealth product. Now it’s a part of the Amazon Basic Care Brand, the product is the exact same formulations, size, and quality.

#TOP4

Alka-Seltzer Effervescent Gold, 36 Tablets, Pack Of 3

ALKA-SELTZER
56675
6.00 X 4.00 X 4.00 Inches
0.28 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Kazer 9.95

Features

For the relief of: heartburn, acid indigestion, sour stomach.

The package weight of the product is 13.8 ounces

The package dimension of the product is 8.6cmL x 10.9cmW x 15.7cmH

Country of origin is United States

Sal De Uvas Picot, Effervescent Powder Solution, Antacid, 3-Pack Of 12 Antacid Packets, 3 Boxes

SAL DE UVAS PICOT
0621028
6.45 X 3.45 X 2.30 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Sal de Uvas Picot is like a lifesaver when we have overindulged in food or drink. It helps with a quick relief to heartburn symptoms.

Picot Antacid gives fast relief against indigestion. The ingredients in our product are highly alkaline and, they are excellent neutralizers for stomach acid excess.

Sal de Uvas Picot, effervescent powder, dissolves very fast in the water. It helps adjust stomach pH and provide you with efficient and fast relief, reducing the stomach's heaviness.

Our formula is based on sodium bicarbonate and citric acid; both are antacids. These make Picot a helpful product for fast relief against acidity, reflux, and upset stomach.

Our product, Sal de Uvas Picot, comes in convenient, small, easy-to-carry sachets, so you can always have it on hand.

Prevacid 24Hr Lansoprazole Delayed-Release Capsules, 15 Mg/Acid Reducer, Proton Pump Inhibitor (Ppi) For Heartburn Relief, 42 Count

PREVACID
762864
1.50 X 4.37 X 3.21 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Buy Wise From Us 9.95

Features

24 HOUR HEARTBURN RELIEF: The active ingredient in Prevacid 24HR is lansoprazole, an acid reducer, which helps to keep heartburn pain at bay for 24 hours

REDUCE HEARTBURN: enjoy good meals, good times and a good night's sleep without the pain. Use as directed for 14 days to treat frequent heartburn. Not intended for immediate relief, although some people get complete relief of symptoms within 24 hours

EFFECTIVE HEARTBURN TREATMENT: Prevacid 24HR is a 14-day course treatment and clinically proven to treat frequent heartburn.

TREATS HEARTBURN DAY AND NIGHT: Prevacid 24HR prevents stomach acid that causes frequent heartburn and its unpleasant symptoms. So why treat after you start feeling the burn.

PROTON PUMP INHIBITOR: Prevacid 24HR turns off the pumps that produce the acid that causes heartburn.

#TOP7

Alka Seltzer Extra Strength Heartburn Relief Chews, Assorted Fruit Antacid Tablets For Acid Indigestion, Upset Stomach And Sour Stomach Relief - 60 Count

ALKA-SELTZER
55459
7.55 X 2.52 X 4.63 Inches
0.51 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Arkip 7.26

Features

TRUSTED BRAND: Alka Seltzer has been a trusted brand for over 80 years

FAST ACTING: starts neutralizing acid in seconds

MULTI SYMPTOM RELIEF: fast relief of heartburn, acid indigestion, sour stomach, and upset stomach related to these symptoms

EASY TO TAKE FORM: Alka Seltzer offers easy to eat and delicious chewable tablets

DELICIOUS FLAVORS: This product comes in delicious lemon, orange and strawberry flavors

Tums Tablets

TUMS
GL49180
1.65 X 3.12 X 3.65 Inches
0.26 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Comes in a container

Reduces stomach acid

Take two or three

Instantly neutralizes acid

Take on the go

HSA and FSA eligible product

Mylanta Antacid And Gas Relief, Maximum Strength Formula, Vanilla Caramel Flavor, 12 Fluid Ounce

MYLANTA
81990301029
2.20 X 3.00 X 7.20 Inches
0.75 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

New Smooth Creamy Taste and Extra Coating Power

Tough on heartburn and Gentle on your body

Works on contact

Multi-Symptom Relief

Paraben-Free

Easy grip bottle; dosage cup included

Target gender: unisex

Brioschi Italian Lemon Flavored Effervescent Heartburn, Upset Stomach, Acid Indigestion, 8.5 Oz Glass Bottle

BRIOSCHI
CHARCM-81
0.53 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
JF Distributions 9.98

Features

Refreshing Effervescent Digestive Aid

Gluten Free. No artificial flavors, no colorants.

Drink and enjoy while bubbly.

Natural Lemon Flavor

Product of Italy

Maty’s Acid & Indigestion Relief Capsules – Safe & Effective, All Natural Heartburn Antacid Alternative Made With Apple Cider Vinegar, Ginger & Turmeric – 60 Count (30 Servings)

MATYS
20899874002333
2.39 X 2.39 X 4.38 Inches
4.00 ounces
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
California Distribution Inc 9.57

Features

Drug-Free Relief from Heartburn: Our safe, natural alternative works with your body to relieve occasional acid indigestion and heartburn; safe for everyday use to help relieve incidents of heartburn & indigestion

Made with Whole Food Ingredients: Each of our products are naturally drug-free and derived from whole food ingredients you know, recognize and can pronounce, like apple cider vinegar, turmeric and ginger.

No Added Sugar, Flavors, Colors or Preservatives: Maty's natural heartburn remedy contains healthy, functional ingredients to relieve occasional heartburn and indigestion; it’s aluminum-free, talc-free, alcohol-free, dairy-free, gluten-free, drug-free and chemical-free (for chronic conditions, consult your healthcare provider)

Intentionally Crafted Remedies: At Maty’s, we believe in the power of Mother Nature and functional foods to help you feel better, using only real ingredients to provide real relief; as with any natural dietary supplement, it may be more effective in some cases than others

For Relief from Occasional Heartburn & Indigestion: If you are a first time user, start with one capsule and slowly work up to two; Can be taken with meals or at the first sign of symptoms for relief; best when taken with at least 6 oz of water.

Wonderbelly Antacid Chewable Tablets - Maximum Strength Calcium Carbonate Acid Neutralizer - Instant Heartburn Relief, Acid Indigestion & Sour Stomach -Vegan (Strawberry Milkshake)

WONDERBELLY
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Wonderbelly 5.79

Features

Maximum Strength & Instant Relief: Wonderbelly Antacid tablets provide maximum strength and instant relief from heartburn, acid indigestion and related upset stomach with a great taste and clean ingredients. Includes one bottle of 60 chewable Strawberry Milkshake flavored tablets with 1000MG each of Calcium Carbonate.

Clean Relief: Instantly soothe your heartburn and sour stomach with clean ingredients. Wonderbelly is free from talc, dyes, parabens, preservatives, common allergens, artificial sweeteners and is vegan, dairy free, gluten free, and NON-GMO Project Verified.

Delicious Flavor: The Strawberry Milkshake flavor tastes like strawberries blended into your favorite sweet vanilla ice cream, topped with a dollop of whipped cream.

No Plastic, Just Happy Bellies: We put the planet first every step of the way. Join us and start making your medicine cabinet 100% plastic-free with our aluminum containers.

Same Effectiveness as Leading Brands: Wonderbelly Antacid is real medicine that fights heartburn, acid indigestion, sour belly and related upset stomach with the same effective, active ingredient as the leading brands while using clean, non-gmo inactive ingredients.

#TOP13

Hilma Heartburn & Indigestion Relief - Natural Antacid For Occasional Acid Reflux & Heartburn - Ginger, Chamomile, Marshmallow Root & More - Doctor-Formulated & Clincially-Studied - 50 Vegan Capsules

HILMA
STOMF_50
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Hilma Natural Remedies 9.67

Features

Occasional Heartburn + Indigestion? - Get effective, drug-free relief. Hilma uses herbs that relieve occasional acid reflux + heartburn: Chamomile, Ginger, Marshmallow Root, DGL Licorice, Artichoke Leaf.* Ditch the chalky, sugary pills and syrups.

Clinically Studied - In an independent clinical study with over 100 participants, 94% saw decreased upset stomach in 30 minutes after taking Hilma Occasional Heartburn + Indigestion Relief.

Perfect For - When you’re feeling the burn after a big meal, or when your stomach is feeling unsettled from travel or stress. Take 2 easy-to-swallow capsules as needed.

Only The Best Ingredients - Clean Label Project certified. Naturally drug-free, Non-GMO, Gluten Free, Vegan, Cruelty Free, Nut Free, Soy Free. No synthetic colors, fillers, dyes, sweeteners, or flavors. Always 3rd party lab tested.

Hilma Brand Story - We are a women-owned and led company that has created a new standard for the medicine cabinet--natural remedies, backed by science and formulated with the highest quality ingredients. We guarantee 100% happiness on every order.

#TOP14

Alka- Seltzer Lemon Lime, 36-Count

ALKA-SELTZER
B0043OYBQ8
4.00 X 3.40 X 2.05 Inches
1.30 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
KaYTo 9.18

Features

Fast Relief of Acid Indigestion, Sour Stomach, Heartburn, Body Aches & Pains, and Headache

Gently Breaks Up and Dissolves Away the Full Feeling of Indigestion and Pain Fast

Original formula antacid, providing trusted, effective, effervescent relief for over 74 years

Refreshing lemon-lime flavor

#TOP15
Best For Tums

Tums Antacid Chewable Tablets For Travel, 12 Rolls Extra Strength Fast Acting Chewy Bites Assorted Berry Flavor For Heartburn Relief And Acid Indigestion Relief Calcium With Np Mints Packet, 96 Pieces

NOSH PACK
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Number 1 In Service 9.94

Features

Tums Chewy Bites - Provides fast acting extra strength relief for heartburns. Comes with total of 96 Tums and Nosh Pack Mints

Travel Size Tums -12 small rolls with 8 pieces in each so you can take them with you anywhere. Now you will never get stuck with a heartburn on the go!

Calcium Carbonate is the most efficient way to get rid of heartburns, goes to work in seconds to relieve digestion issues

Relieves heartburn, sour stomach, acid indigestion and upset stomach associated with these symptoms

#TOP16

Goodsense Effervescent Antacid And Pain Relief, Blue, 36 Count

GOOD SENSE
TW00148
2.12 X 3.37 X 4.00 Inches
0.05 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
myREVCO 9.73

Features

Prevents heartburn

Treats upset stomach

Cures headache

Treats body aches and pains

Contains 36 tablets

Equate Extra Strength Heartburn Relief + Gas Relief Chews, Mixed Berry, 54 Ct Bundle With Exclusive "Say "No" To Indigestion And Heartburn" - Better Idea Guide (2 Items)

IDEA SHOP USA
WMT-5D58C-EQHEARTBR-54CT-1P
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
IDEA SHOP USA 9.75

Features

Relieves heartburn, sour stomach, acid indigestion, and stomach ache

Helps symptoms such as bloating, pressure, and gas

Gluten-free

Soft, chewable tablets

The tasty mixed berry flavor

#TOP18

Quality Choice, Extra Strength Effervescent Antacid And Pain Relief Tablets, Relief From Acid Indigestion, Upset Stomach, Heartburn, Body Aches And More, 24 Effervescent Tablets

QUALITY CHOICE
QC99790
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
PLQC 9.84

Features

Quality Choice Extra Strength Effercescent Antacid & Pain Relief Tablets compares to the Active Ingredients in Alka-Seltzer Extra Strength

Extra Strength Antacid & Pain Relief is Used to Treat Heartburn, Acid Indigestion, and Sour Stomach when accompanied by Headache or Body Aches and Pains.

Extra Strength Effervescent Antacid is commonly used when you experience an upset stomach following from overindulgence in food or drink.

Extra Strength Antacid and Pain relief by Quality Choice contains Anhydrous Citric Acid 1000 mg (Antacid), Aspirin 500 mg (Pain Reliever), and Sodium Bicarbonate (heat-treated) 1985 mg (Antacid)

Each Package of Antacid and Pain Relief contains 24 Effervescent Tablets.

Top 10 antacids alka seltzer Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Alka-Seltzer 36
Sal De Uvas Picot 3
Tums 3
Amazon Basic Care 2
Alka Seltzer Pm 1
Brioschi 1
Good Sense 1
Hilma 1
Idea Shop Usa 1
Matys 1

Top 10 antacids alka seltzer Brands Pie Chart


We've carried out a comprehensive analysis of 131,463 reviews on antacids alka seltzer, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select antacids alka seltzer priced around $18.61, with top brands including alka-seltzer, tums, wonderbelly, sal de uvas picot, alka seltzer pm, healtha2z, advil, matys and prevacid and mylanta

Our team of expert editors reviewed these high-quality items and handpicked the top 18 antacids alka seltzer for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, kackol shopping, wonderbelly, worldwidesuperstore, spak wala, khyber llc, versure, smartz choices and clickandship and the customer land .

We are dedicated to assisting our users in finding the right antacids Products based on their needs, saving them considerable time when choosing which antacids alka seltzer to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.