Best Packet Cold Medicine in 2026

ACTIVE INGREDIENTS: This cold and flu medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant) which compare to the active ingredients in Vicks DayQuil Cold and Flu

MULTI-SYMPTOM RELIEF: Temporarily relieves headache, fever, sore throat, minor aches and pains, nasal congestion and cough due to the common cold and flu

NON-DROWSY: Each dose is designed for daytime use, so you can get through the day

ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Cold & Flu and Vicks NyQuil Cold & Flu

NON-DROWSY DAYTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains

NIGHTTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains

ACTIVE INGREDIENTS: This product contains acetaminophen (pain reliever and fever reducer), dextromethorphan HBr (cough suppressant) and doxylamine succinate (antihistamine) which compares to the active ingredients in Vicks NyQuil Cold & Flu.

POWERFUL NIGHTTIME RELIEF: This cold and flu medicine provides multi-symptom relief of common cold and flu symptoms while you sleep.

PAIN RELIEVER AND FEVER REDUCER: Relieves sore throat, minor aches and pains and reduces fever associated with the common cold and flu.

ACTIVE INGREDIENTS: This cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant). Compare to the active ingredients in Vicks DayQuil Cold & Flu LiquiCaps

MULTI-SYMPTOM RELIEF: This cold remedy temporarily relieves headache, fever, sore throat, minor aches and pains, nasal congestion and cough due to the common cold and flu

COUGH SUPPRESSANT: Choose the right cold remedy for your cough during cold and flu season. This product acts as a cough suppressant to temporarily relieve coughing due to minor throat and bronchial irritation

ACTIVE INGREDIENTS: This cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant). Compare to the active ingredients in Vicks DayQuil Cold & Flu LiquiCaps.

MULTI-SYMPTOM RELIEF: This cold remedy temporarily relieves headache, fever, sore throat, minor aches and pains, nasal congestion and cough due to the common cold and flu.

PAIN RELIEVER AND FEVER REDUCER: Cold relief medicine temporarily relieves minor aches and pains, headache, fever and sore throat due to the common cold and flu.

COMPARE AND SAVE: Compare to the ingredients in Ocean. Amazon Basic Care Premium Saline Nasal Moisturizing Spray contains sodium chloride 0.65%, phenylcarbinol and benzalkonium chloride as preservatives.

SOOTHES DRY NASAL PASSAGES: This saline nasal spray relieves dry nasal membranes.

SALINE NASAL SPRAY provides non-medicated relief for irritated and dry nasal passages.

ACTIVE INGREDIENTS: Amazon Basic Care Mucus DM contains Dextromethorphan HBr 30 mg (a cough suppressant) and Guaifenesin 600 mg (an expectorant), which compare to the active ingredients in Mucinex DM

12 HOUR RELIEF: Provides up to 12 hours of chest congestion relief; gluten-free expectorant and cough suppressant

EXPECTORANT: Helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive

ACTIVE INGREDIENTS: This product contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant) which compare to the active ingredients in Theraflu Multi-Symptom Severe Cold.

HOT LIQUID COLD AND FLU RELIEF: Each packet dissolves in hot water and provides daytime cold and flu relief from common symptoms such as nasal and sinus congestion, sore throat pain, cough, headache, body ache and fever.

NON-DROWSY: When used as directed, this hot liquid cold and flu relief is a non-drowsy solution for cold symptoms such as nasal and sinus congestion, sore throat pain, cough, headache, body ache and fever.

ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Severe Cold and Flu: acetaminophen, dextromethorphan HBr, guaifenesin, and phenylephrine HCl

MAXIMUM STRENGTH: Amazon Basic Care Severe Daytime Cold and Flu Relief provides maximum strength relief of headache, fever, sore throat, minor aches and pains, nasal and sinus congestion, sinus pressure, cough and chest congestion

NON-DROWSY DAYTIME RELIEF: This non-drowsy daytime medicine provides powerful relief of severe symptoms so you can take on the day; alcohol and antihistamine free

ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks NyQuil Severe Cold and Flu, acetaminophen 650 mg, dextromethorphan HBr 20 mg, doxylamine succinate 12.5 mg and phenylephrine HCl 10 mg

MAXIMUM STRENGTH RELIEF: Each dose includes a pain reliever/fever reducer, cough suppressant, antihistamine and nasal decongestant so you can rest; this medicine also contains ten percent alcohol

FOR NIGHT TIME USE: Amazon Basic Care Night Time Severe Cold and Flu Relief soothes your severe symptoms to help you sleep

ACTIVE INGREDIENTS: Contains acetaminophen 650 mg, dextromethorphan HBr 20 mg, doxylamine succinate 12.5 mg, and phenylephrine HCl 10 mg, which compares to the active ingredients in Vicks NyQuil Severe

MAXIMUM STRENGTH: Amazon Basic Care Nighttime Severe Cold and Flu Relief provides maximum strength relief of headache, fever, sore throat, minor aches and pains, sinus congestion and pressure, sneezing, runny nose and cough

NIGHTTIME RELIEF: Provides cold care through the night; this cold and flu medicine relieves cold and flu symptoms so you can rest; does not contain pseudoephedrine

ACTIVE INGREDIENTS: The active ingredients in Severe Cold, Flu and Cough are acetaminophen 650 mg, pain reliever/fever reducer; diphenhydramine HCl 25 mg, antihistamine/cough suppressant; phenylephrine HCl 10 mg, nasal decongestant which compares to Theraflu Severe Cold and Cough active ingredients.

FAST RELIEF: Severe Cold, Flu and Cough offers hot liquid therapy for fast relief of nasal and sinus congestion, cough, runny nose, sneezing, body ache, sore throat pain, headache and fever.

CONVENIENT PACKETS: Dissolve powder into 8 oz. of hot water and sip while hot for nighttime cold and flu relief. Take every four hours while symptoms persist.

ACTIVE INGREDIENT: Amazon Basic Care Cough and Mucus Relief contains Guaifenesin 600 mg, an expectorant; compare to the active ingredient in Mucinex

12-HOUR RELIEF: Get immediate and long-lasting chest congestion relief; just one dose releases the regular strength phlegm relief medicine you need and lasts for up to 12 hours

COUGH EXPECTORANT: Trust Guaifenesin 600 mg to thin and loosen mucus to make coughs more productive

ACTIVE INGREDIENT: The active ingredient in Amazon Basic Care Nasal Decongestant PE is Phenylephrine HCl 10 mg, a nasal decongestant, which compares to the active ingredient in Sudafed PE Congestion

NASAL DECONGESTANT: This product provides maximum strength, non-drowsy relief for nasal and sinus congestion, and sinus pressure due to the common cold, hay fever or other upper respiratory allergies

MAXIMUM STRENGTH: This nasal decongestant provides powerful relief for sinus pressure, nasal and sinus congestion

ACTIVE INGREDIENTS: Amazon Basic Care NightTime Cough Relief contains dextromethorphan HBr (Cough Suppressant) and doxylamine succinate (antihistamine), which compare to the active ingredients in Vicks NyQuil Cough

ALL NIGHT COUGH RELIEF:Amazon Basic Care NightTime Cough Relief temporarily relieves your cough so you can get the rest you need

MULTI-SYMPTOM RELIEF: Temporarily relieves cold symptoms such as cough, runny nose and sneezing

ACTIVE INGREDIENT: Amazon Basic Care Maximum Strength Chest Congestion and Mucus Relief Extended-Release Tablets contain Guaifenesin, 1200 mg, an expectorant; compares to the active ingredient in Maximum Strength Mucinex

12-HOUR DECONGESTANT: Get immediate and long-lasting chest congestion relief; just one dose releases the maximum strength phlegm relief medicine you need immediately and lasts for up to 12 hours

MAXIMUM STRENGTH COUGH EXPECTORANT: This chest congestion medicine provides maximum strength relief by loosening phlegm (mucus) and thinning bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive

ACTIVE INGREDIENTS: Contains acetaminophen (pain reliever/fever reducer), phenylephrine HCl (nasal decongestant), dextromethorphan HBr (cough suppressant) and guaifenesin (expectorant). Compare to Vicks DayQuil Severe+ VapoCOOL active ingredients

MAXIMUM STRENGTH: Amazon Basic Care Vapor Ice Daytime Severe Cold & Flu is a maximum strength liquid cold and flu medicine in soothing Vapor Ice flavor. Relieves cold and flu symptoms to help you get through the day

COLD AND FLU MEDICINE: Amazon Basic Care Vapor Ice Daytime Severe Cold & Flu is a maximum strength liquid medicine in soothing Vapor Ice flavor

ACTIVE INGREDIENTS: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu help to relieve common cold and flu symptoms, day and night; compare to the active ingredients in Vicks DayQuil and NyQuil Severe VapoCOOL

EFFECTIVE: Daytime relieves minor aches and pains, fever, nasal congestion, sinus pressure, cough and chest congestion; Nighttime relieves minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough

COMBINATION PACK: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu comes in a combination pack for around-the-clock maximum strength, multi-symptom relief for your worst cold and flu symptoms

ACTIVE INGREDIENTS: This cold medicine contains a pain reliever/fever reducer, cough suppressant, expectorant and nasal decongestant. Compare to the active ingredients in Robitussin Severe Multi-Symptom Cough Cold + Flu.

MAXIMUM STRENGTH: This cold medicine provides maximum strength relief of multiple cold and flu symptoms such as cough, nasal congestion, sinus congestion and pressure, minor aches and pains, sore throat, headache and temporarily reduces fever.

MUCUS RELIEF: Take this cold medicine to help loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make coughs more productive.

CONTAINS 1 - 10ML (.34oz). Up to 40 sublingual doses for long lasting allergy relief.

EFFECTIVE & SAFE RELIEF from allergy symptoms such as stuffy, runny nose, nasal congestion, sneezing, postnasal drip, sinus pain itchy nose and throat, cough, watery, itchy, red eyes and fatigue.

NATURAL, NON-DROWSY, NON-HABIT FORMING, long lasting, effective natural antihistamine for allergies. Treats seasonal allergy symptoms caused by hay fever, upper respiratory allergies, pollen, trees, grasses, ragweed and animal dander.