Best Vicks Cough Sore Throat Medicine in 2026

Daisy
Last Updated: Jul 20, 2026

At a Glance: Our Top Picks for Vicks Cough Sore Throat Medicine

Amazon Basic Care Cold & Flu Relief Multi-Symptom Daytime/Nighttime Combo Pack Softgels, 48 Count
#TOP1
Amazon Basic Care Cold & Flu Relief Multi-Symptom
9.9
PM SCORE
Amazon Basic Care Daytime Cold & Flu Liquid, Orange Flavor, 8 Fluid Ounces
#TOP2
Amazon Basic Care Daytime Cold & Flu Liquid,
9.9
PM SCORE
Amazon Basic Care Daytime Cold and Flu Relief Softgels, Non-Drowsy, Relief of Pain, Fever, Cough, Sore Throat, Nasal Congestion, 48 Count
#TOP3
Amazon Basic Care Daytime Cold And Flu Relief
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Vicks Cough Sore Throat Medicine of 2026

Market Overview
Vicks Cough Sore Throat Medicine Reviewed
  • Reviews Analyzed: 96785 Items
  • PM Avg. Rating: 9.8 / 10
17 Products Evaluated
  • Highest Price: $12.21
  • Lowest Price: $4.47
  • Avg. Price: $8.69

Amazon Basic Care Cold & Flu Relief Multi-Symptom Daytime/Nighttime Combo Pack Softgels, 48 Count

AMAZON BASIC CARE
58072
4.38 X 2.00 X 3.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Cold & Flu and Vicks NyQuil Cold & Flu

NON-DROWSY DAYTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains

NIGHTTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains

PAIN RELIEVER AND FEVER REDUCER: Both Daytime and Nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat

COLD AND FLU: Influenza (flu) and the common cold are respiratory illnesses caused by viruses. A cold medicine like Cold & Flu Relief Multi-Symptom Daytime/Nighttime can help

Amazon Basic Care Daytime Cold & Flu Liquid, Orange Flavor, 8 Fluid Ounces

AMAZON BASIC CARE
0615190
2.18 X 2.25 X 6.48 Inches
0.67 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: This cold and flu medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant) which compare to the active ingredients in Vicks DayQuil Cold and Flu

MULTI-SYMPTOM RELIEF: Temporarily relieves headache, fever, sore throat, minor aches and pains, nasal congestion and cough due to the common cold and flu

NON-DROWSY: Each dose is designed for daytime use, so you can get through the day

MAXIMUM STRENGTH: When a cold or flu strikes, you need powerful relief

FOR AGES 6 AND OVER: For adults and children ages 6 and older; take as directed for cold and flu medicine that is alcohol, antihistamine and gluten free

Amazon Basic Care Daytime Cold And Flu Relief Softgels, Non-Drowsy, Relief Of Pain, Fever, Cough, Sore Throat, Nasal Congestion, 48 Count

AMAZON BASIC CARE
SB-123
2.00 X 4.38 X 3.25 Inches
0.30 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: This cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant). Compare to the active ingredients in Vicks DayQuil Cold & Flu LiquiCaps

MULTI-SYMPTOM RELIEF: This cold remedy temporarily relieves headache, fever, sore throat, minor aches and pains, nasal congestion and cough due to the common cold and flu

COUGH SUPPRESSANT: Choose the right cold remedy for your cough during cold and flu season. This product acts as a cough suppressant to temporarily relieve coughing due to minor throat and bronchial irritation

NASAL DECONGESTANT: Cold and flu season often brings nasal congestion as a symptom. This cold relief medicine will help temporarily relieve this symptom

An Amazon Brand

Amazon Basic Care Nite Time Cold Flu Relief Softgels, Pain Reliever, Fever Reducer, Cough Suppressant Antihistamine, 48 Count

AMAZON BASIC CARE
SB-123
2.00 X 4.38 X 3.25 Inches
0.30 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: This product contains acetaminophen (pain reliever and fever reducer), dextromethorphan HBr (cough suppressant) and doxylamine succinate (antihistamine) which compares to the active ingredients in Vicks NyQuil Cold & Flu.

POWERFUL NIGHTTIME RELIEF: This cold and flu medicine provides multi-symptom relief of common cold and flu symptoms while you sleep.

PAIN RELIEVER AND FEVER REDUCER: Relieves sore throat, minor aches and pains and reduces fever associated with the common cold and flu.

COUGH SUPPRESSANT: This nighttime cold and flu relief medicine helps to relieve coughing so you can rest.

ANTIHISTAMINE: Helps relieve runny nose and sneezing associated with the common cold and flu.

Amazon Basic Care Daytime Cold And Flu Relief Softgels, Non-Drowsy Cold Medicine, Relief Of Pain, Fever, Cough, Sore Throat, Nasal Congestion, 24 Count

AMAZON BASIC CARE
YAO468
1.00 X 4.38 X 3.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: This cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant). Compare to the active ingredients in Vicks DayQuil Cold & Flu LiquiCaps.

MULTI-SYMPTOM RELIEF: This cold remedy temporarily relieves headache, fever, sore throat, minor aches and pains, nasal congestion and cough due to the common cold and flu.

PAIN RELIEVER AND FEVER REDUCER: Cold relief medicine temporarily relieves minor aches and pains, headache, fever and sore throat due to the common cold and flu.

COUGH SUPPRESSANT: Choose the right cold remedy for your cough during cold and flu season. This product acts as a cough suppressant to temporarily relieve coughing due to minor throat and bronchial irritation.

NASAL DECONGESTANT: Cold and flu season often brings nasal congestion as a symptom. This cold relief medicine will help temporarily relieve this symptom.

Amazon Basic Care Severe Daytime Cold & Flu, Maximum Strength Liquid Medicine, Relieves Aches, Pain, Fever, Cough, Nasal & Chest Congestion, Sore Throat, 8 Fl Oz, Original Flavor

AMAZON BASIC CARE
111568
2.18 X 2.25 X 6.48 Inches
0.67 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Severe Cold and Flu: acetaminophen, dextromethorphan HBr, guaifenesin, and phenylephrine HCl

MAXIMUM STRENGTH: Amazon Basic Care Severe Daytime Cold and Flu Relief provides maximum strength relief of headache, fever, sore throat, minor aches and pains, nasal and sinus congestion, sinus pressure, cough and chest congestion

NON-DROWSY DAYTIME RELIEF: This non-drowsy daytime medicine provides powerful relief of severe symptoms so you can take on the day; alcohol and antihistamine free

EFFECTIVE: Each dose combines a pain reliever/fever reducer, cough suppressant, expectorant and nasal decongestant to soothe your severe daytime symptoms

POWERFUL LIQUID: This liquid medicine in original flavor provides powerful, multi-symptom relief; for adults and children age 6 and over; gluten, alcohol and antihistamine free

Amazon Basic Care Nighttime Severe Cold And Flu Syrup, Max Strength Liquid Cold Medicine, Multi-Symptom Relief, For Adults And Children 12 Years And Older, Mixed Berry Flavor, 12 Fluid Ounces

AMAZON BASIC CARE
SB-123
2.50 X 2.50 X 7.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: Contains acetaminophen 650 mg, dextromethorphan HBr 20 mg, doxylamine succinate 12.5 mg, and phenylephrine HCl 10 mg, which compares to the active ingredients in Vicks NyQuil Severe

MAXIMUM STRENGTH: Amazon Basic Care Nighttime Severe Cold and Flu Relief provides maximum strength relief of headache, fever, sore throat, minor aches and pains, sinus congestion and pressure, sneezing, runny nose and cough

NIGHTTIME RELIEF: Provides cold care through the night; this cold and flu medicine relieves cold and flu symptoms so you can rest; does not contain pseudoephedrine

EFFECTIVE: Each dose contains a pain reliever, fever reducer, cough suppressant, antihistamine and nasal decongestant

MIXED BERRY FLAVOR LIQUID: This liquid cold and flu medicine comes in tasty mixed berry flavor and provides multi-symptom relief; alcohol free, sugar free and gluten free

Amazon Basic Care Severe Daytime Cold And Flu Relief, Maximum Strength Liquid Cold Medicine; Relieves Aches, Pain, Fever, Cough, Nasal Congestion, Sore Throat, Chest Congestion, 12 Fluid Ounces

AMAZON BASIC CARE
2.50 X 2.50 X 7.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

THE ACTIVE INGREDIENTS are acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant), guaifenesin (expectorant) and phenylephrine HCl (nasal decongestant); compare to the active ingredients in Vicks DayQuil Severe Cold and Flu

SEVERE COLD AND FLU RELIEF: Temporarily relieves common cold and flu symptoms, such as headache, fever, sore throat, minor aches and pains, nasal and sinus congestion, sinus pressure, cough and chest congestion

MAXIMUM-STRENGTH PAIN RELIEVER AND FEVER REDUCER: This alcohol-free daytime medicine temporarily eases the discomfort caused by symptoms of the common cold and flu

NASAL DECONGESTANT: This cold medicine relieves nasal and sinus congestion and sinus pressure for non-drowsy relief

COUGH SUPPRESSANT AND EXPECTORANT: Amazon Basic Care Severe Cold and Flu temporarily relieves cough and helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus; makes coughs more productive

Amazon Basic Care Vapor Ice Daytime And Nighttime Severe Cold And Flu, Coated Caplets, Combo Pack, 48 Count

AMAZON BASIC CARE
2.00 X 4.38 X 3.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu help to relieve common cold and flu symptoms, day and night; compare to the active ingredients in Vicks DayQuil and NyQuil Severe VapoCOOL

EFFECTIVE: Daytime relieves minor aches and pains, fever, nasal congestion, sinus pressure, cough and chest congestion; Nighttime relieves minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough

COMBINATION PACK: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu comes in a combination pack for around-the-clock maximum strength, multi-symptom relief for your worst cold and flu symptoms

COATED CAPLETS: Contain pain reliever/fever reducer, cough suppressant, nasal decongestant, antihistamine, expectorant (antihistamine in nighttime only, expectorant in daytime only)

MAXIMUM STRENGTH: Get day and night cold and flu relief with these max strength coated caplets. Relieve sore throat and other cold and flu symptoms with Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu

Amazon Basic Care Nighttime Cold & Flu Relief, Pain Reliever, Fever Reducer, Cough Suppressant, Antihistamine, Cherry Flavor, 12 Fluid Ounces

AMAZON BASIC CARE
2.50 X 2.50 X 7.25 Inches
12.00 ounces
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: Active ingredients are Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, and Doxylamine succinate, 12.5 mg. Compare to the active ingredients of Vicks NyQuil Cold & Flu

RELIEVES COLD & FLU SYMPTOMS: Amazon Basic Care Nighttime Cold & Flu Relief provides multi-symptom relief by helping with common symptoms such as aches, fever, cough, sneezing and runny nose

NIGHTTIME COLD AND FLU RELIEF: Amazon Basic Care Nighttime Cold and Flu Relief relieves cold and flu symptoms so you can rest through the night.

EFFECTIVE: Acts as a pain reliever, fever reducer, cough suppressant and antihistamine.

GLUTEN FREE: This product is Gluten Free. Does not contain Pseudoephedrine; contains 10% ALCOHOL.

Amazon Basic Care Daytime Cold & Flu Liquid; Cold Care For Daytime Cold And Flu, 12 Fluid Ounces

AMAZON BASIC CARE
2.50 X 2.50 X 7.25 Inches
1.00 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: This cold and flu medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant) which compare to the active ingredients in Vicks DayQuil Cold and Flu

MULTI-SYMPTOM RELIEF: Temporarily relieves headache, fever, sore throat, minor aches and pains, nasal congestion and cough due to the common cold and flu

NON-DROWSY: Each dose is designed for daytime use, so you can get through the day

MAXIMUM STRENGTH: When a cold or flu strikes, you need powerful relief

FOR AGES 6 AND OVER: For adults and children ages 6 and older; take as directed for cold and flu medicine that is alcohol, antihistamine and gluten free

Amazon Basic Care Severe Cold & Flu Relief Powder, Relieves Cough, Sore Throat Pain, Body Ache, Headache And Fever, Green Tea & Honey Lemon Flavors, 6 Count

AMAZON BASIC CARE
03282830
1.81 X 3.13 X 5.00 Inches
0.23 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: This product contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant) which compare to the active ingredients in Theraflu Multi-Symptom Severe Cold.

HOT LIQUID COLD AND FLU RELIEF: Each packet dissolves in hot water and provides daytime cold and flu relief from common symptoms such as nasal and sinus congestion, sore throat pain, cough, headache, body ache and fever.

NON-DROWSY: When used as directed, this hot liquid cold and flu relief is a non-drowsy solution for cold symptoms such as nasal and sinus congestion, sore throat pain, cough, headache, body ache and fever.

JUST ADD WATER: Add Severe Cold & Flu Relief powder to hot water for cold and flu hot liquid therapy that provides fast relief of nasal and sinus congestion, sore throat, headache, body aches, fever and cough.

An Amazon brand

Amazon Basic Care Nighttime Severe Cold & Flu Liquid, Original, 12 Fl Oz

AMAZON BASIC CARE
2.50 X 2.50 X 7.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks NyQuil Severe Cold and Flu, acetaminophen 650 mg, dextromethorphan HBr 20 mg, doxylamine succinate 12.5 mg and phenylephrine HCl 10 mg

MAXIMUM STRENGTH RELIEF: Each dose includes a pain reliever/fever reducer, cough suppressant, antihistamine and nasal decongestant so you can rest; this medicine also contains ten percent alcohol

FOR NIGHT TIME USE: Amazon Basic Care Night Time Severe Cold and Flu Relief soothes your severe symptoms to help you sleep

MULTI-SYMPTOM RELIEF: Temporarily relieves common cold and flu symptoms: fever, minor aches and pains, sore throat, coughing, sneezing, runny nose and sinus pressure

SOOTHES COLD AND FLU SYMPTOMS: Promotes nasal and/or sinus drainage and temporarily restores freer breathing through the nose; this medicine is sugar free and gluten free; for ages 12 and older

Amazon Basic Care Nighttime Severe Cold, Flu And Cough Suppressant Medicine Powder, Pain Reliever/Fever Reducer, Nasal Decongestant, Antihistamine, Honey Lemon Infused With White Tea Flavors, 6 Count

AMAZON BASIC CARE
0615424
1.81 X 3.13 X 5.00 Inches
0.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

ACTIVE INGREDIENTS: The active ingredients in Severe Cold, Flu and Cough are acetaminophen 650 mg, pain reliever/fever reducer; diphenhydramine HCl 25 mg, antihistamine/cough suppressant; phenylephrine HCl 10 mg, nasal decongestant which compares to Theraflu Severe Cold and Cough active ingredients.

FAST RELIEF: Severe Cold, Flu and Cough offers hot liquid therapy for fast relief of nasal and sinus congestion, cough, runny nose, sneezing, body ache, sore throat pain, headache and fever.

CONVENIENT PACKETS: Dissolve powder into 8 oz. of hot water and sip while hot for nighttime cold and flu relief. Take every four hours while symptoms persist.

COMFORTING WARMTH WITH GREAT TASTE: This flu medicine relieves pain with soothing honey lemon infused with white tea flavors.

ALCOHOL-FREE COLD AND FLU POWDER: This product contains no alcohol or gluten.

Amazon Basic Care Nighttime Severe Vapor Ice Cold And Flu, Coated Caplets, Temporarily Relieves Common Cold And Flu Symptoms Like Runny Nose And Sneezing

AMAZON BASIC CARE
1.00 X 4.38 X 3.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: This product contains a pain reliever/fever reducer, cough suppressant, antihistamine and nasal decongestant. Compare to the active ingredients in Vicks NyQuil Severe+ VapoCOOL

EFFECTIVE: Temporarily relieves common cold and flu symptoms such as nasal congestion, sinus congestion and pressure, runny nose and sneezing, minor aches and pain, sore throat and cough

COATED CAPLETS provide maximum strength, common cold and flu symptom relief

NIGHTTIME COLD and FLU RELIEF for minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough

VAPOR ICE: Soothing Vapor Ice flavor in gluten free cold and flu symptom medicine

Amazon Basic Care Vapor Ice Daytime And Nighttime Severe Cold And Flu, Coated Caplets, Combo Pack, 24 Count

AMAZON BASIC CARE
YAO946
1.50 X 4.38 X 3.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu help to relieve common cold and flu symptoms, day and night; compare to the active ingredients in Vicks DayQuil and NyQuil Severe VapoCOOL

EFFECTIVE: Daytime relieves minor aches and pains, fever, nasal congestion, sinus pressure, cough and chest congestion; Nighttime relieves minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough

COMBINATION PACK: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu comes in a combination pack for around-the-clock maximum strength, multi-symptom relief for your worst cold and flu symptoms

COATED CAPLETS: Contain pain reliever/fever reducer, cough suppressant, nasal decongestant, antihistamine, expectorant (antihistamine in nighttime only, expectorant in daytime only)

MAXIMUM STRENGTH: Get day and night cold and flu relief with these max strength coated caplets. Relieve sore throat and other cold and flu symptoms with Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu

Amazon Basic Care Tussin Severe Cf Max Syrup, Multi-Symptom Cough, Cold And Flu Liquid Medicine, Non-Drowsy, Relieves Cough, Sore Throat, Body Aches, Fever, Nasal And Chest Congestion, 8 Fl Oz

AMAZON BASIC CARE
2.38 X 2.34 X 6.19 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: This cold medicine contains a pain reliever/fever reducer, cough suppressant, expectorant and nasal decongestant. Compare to the active ingredients in Robitussin Severe Multi-Symptom Cough Cold + Flu.

MAXIMUM STRENGTH: This cold medicine provides maximum strength relief of multiple cold and flu symptoms such as cough, nasal congestion, sinus congestion and pressure, minor aches and pains, sore throat, headache and temporarily reduces fever.

MUCUS RELIEF: Take this cold medicine to help loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make coughs more productive.

NON-DROWSY: This non-drowsy cold and flu medicine provides relief for adults and children age 12 years and over. Dosage cup included.

GREAT TASTING COLD MEDICINE: Amazon Basic Care Tussin CF Max, Multiple Symptom Cough Cold & Flu is gluten free, sugar free and alcohol free. Maximum strength claim based on maximum levels of active ingredients per 4 hour dose.

Top 10 cough sore throat medicine Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Amazon Basic Care 17

Top 10 cough sore throat medicine Brands Pie Chart


We've carried out a comprehensive analysis of 96,785 reviews on cough sore throat medicine, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select cough sore throat medicine priced around $8.69, with top brands including mucinex, boiron, chloraseptic, vicks, theraflu, alka-seltzer plus, robitussin, hyland's and sucrets and ricola

Our team of expert editors reviewed these high-quality items and handpicked the top 17 cough sore throat medicine for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, nc commercial, greatprices4u, bnt distributor, incredible designs llc, name brand overstock, healthy products a plus llc, the customer land and beekeeper's naturals and focus health .

We are dedicated to assisting our users in finding the right medicine Products based on their needs, saving them considerable time when choosing which cough sore throat medicine to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.