Best Paleo Digestive Supplements in 2026

More Magnesium In Each Capsule - This magnesium complex supplement contains highly absorbable magnesium with each capsule providing 150 mg of elemental magnesium. Chelated magnesium can support a sense of calm, bone health, restful nights, and muscle health.*

Improved Absorption - Magnesium glycinate chelate can bypass normal modes of absorption in the intestine, which helps allow larger amounts of magnesium to be absorbed more quickly.* Magnesium complex supplement

Easier On The Stomach - Love magnesium, but not its digestive impact? Buffered chelated magnesium should not cause the unfavorable GI symptoms associated with magnesium supplements due to the very stable chelate formed between two glycine molecules and each magnesium ion via a patented process.

More Magnesium, Fewer Pills - This magnesium complex supplement contains highly absorbable magnesium with each capsule providing 150 mg of elemental magnesium. Chelated magnesium can support a sense of calm, bone health, restful nights, and muscle health.*

Improved Absorption with Magnesium Glycinate - Magnesium glycinate chelate can bypass normal modes of absorption in the intestine, which helps allow larger amounts of magnesium to be absorbed more quickly.*

Easier On The Stomach - Love magnesium, but not its digestive impact? Buffered chelated magnesium should not cause the unfavorable GI symptoms associated with magnesium supplements due to the very stable chelate formed between two glycine molecules and each magnesium ion via a patented process.

A combination of herbs, nutrients, and enzymes for modulating the inflammatory response, supporting the natural clearance of proteins like kinin and fibrin, and supporting healthy lymphatic drainage.*

Proprietary blend of proteolytic enzymes, curcumin (turmeric), quercetin, ginger, rutin, rosemary & resveratrol.

The ingredients in Inflammatone provide natural support for a healthy inflammatory response and help protect against oxidative stress.*

Shelf-Stable, Broad-Acting Probiotics - 50 billion CFU evidence-based digestive probiotic using 10 of the most highly-researched, validated probiotic strains. Designed to support gut health, a healthy immune response, and normal bowel movements.*

Survives Stomach Acid (No Refrigeration Required) - These specific strains are capable of surviving the harsh journey to the intestines, where they can grow and function effectively. The probiotic pills are encased in delayed release technology capsules. Unique moisture-resistant, desiccant-lined packaging helps further enhance survivability of this probiotic supplement.

Is Your Probiotic Transparent? An exceptional probiotic will list the specific strain and CFU count for each individual probiotic strain. ProbioMed offers label transparency on both lactobacillus and bifidobacterium probiotic strains, including an acidophilus probiotic, lactobacillus casei, bifidobacterium longum, and lactobacillus plantarum.

Supports a Healthy Inflammatory Response - A comprehensive blend of specialized protein-degrading or proteolytic enzymes, polyphenols and botanical extracts designed to promote a healthy inflammatory response and support the body’s ability to break down specific protein structures that are produced during the natural inflammatory process.*

Antioxidant & Joint Support - Helps maintain healthy joints. Supports the body’s antioxidant status. May support the body’s repair process after injury.*

Contains InflammEnz Enzymes - a clinically researched proprietary proteolytic enzyme blend that is highly resistant to stomach acid and can be absorbed intact from the small intestine into the bloodstream.*

Support Food Breakdown + Nutrient Absorption - This digestive enzyme supplement is a multi enzyme blend of a proprietary blend of digestive enzymes alongside betaine HCl with pepsin to support optimal digestion of proteins, fats, and carbohydrates.*

Occasional Gas or Bloating After Meals? The use of Digestzyme before meals may offer occasional bloating relief. Enzymes may be helpful for those experiencing occasional gas after eating, constipation, or a feeling of fullness after eating only a small quantity of food.* Take one digestion supplement capsule before meals for digestive support.*

Synergistic Enzyme Blend - Contains protease DPP IV (dipeptidyl peptidase IV), which aids in the breakdown of casomorphin (from casein protein) and gluteomorphin (from gluten). Lactase enzyme helps break down the dairy sugar lactose. Also includes a blend of lipase amylase bromelain enzymes.

PROMOTE GUT HEALTH - Glutamine is essential to the health of the immune system and the digestive tract. In the gut, it promotes the health and proper functioning of mucosal cells, which are necessary for normal healing and repair. *

SUPPORT MUSCLE REPAIR - Glutamine also supports optimal muscle growth and strength and has been shown to be particularly useful in helping to maintain muscle tissue in already healthy individuals.*

ANTIOXIDANT ACTIVITY - Increases production of glutathione, the body's main antioxidant.*

L-Glutamine Capsules - 850mg of 'Free Form' L-glutamine in just one vegetarian capsule.

Immune & Gut Health - L-glutamine is essential for the health of the immune system and the digestive tract. In the gut it promotes the health and function of the mucosal cells for normal repair.*

Muscle Maintenance - L-Glutamine also supports optimal muscle growth and strength and has been shown to be particularly useful in helping to maintain muscle tissue.*

MAXIMUM ABSORPTION - This patented Magnesium Bisglycinate Chelate allows larger amounts of magnesium to be absorbed more quickly and be better retained by the body, as compared to many other forms.*

EASY ON THE STOMACH - Love magnesium, but not its digestive impact? This product should not cause any of the unfavorable GI symptoms sometimes associated with magnesium supplementation due to the very stable chelate.*

GET MORE FROM YOUR MAGNESIUM - Magnesium chelates can bypass normal modes of absorption in the intestine, where they would otherwise compete with other minerals. Designs for Health uses the latest research to help you get the most from this 200 mg serving of potent Magnesium, in just two easy tablets.*

DAIRY AND LACTOSE FREE - Unlike other products containing this organism, FloraMyces is free of dairy and lactose, making it a suitable probiotic for dairy-sensitive individuals.*

TEMPERATURE TOLERANT AND ACID RESISTANT - It is rare to find a quality probiotic that does not require refrigeration. This product is freeze-dried, temperature-tolerant, acid-resistant, and remains viable without refrigeration.*

HIGHER STANDARDS. BETTER RESULTS - Designs for Health maintains a strict, no-compromises approach to quality raw material selection. We never cut corners with substandard ingredients. This product is Non-GMO, Gluten-Free, and Vegetarian-friendly.

You Are What You Absorb - A proper diet is the foundation for good health and maintaining an appropriate body. However, the well-known phrase "you are what you eat" is only part of the equation. We are not just what we eat; we are also what we digest, absorb, and assimilate. If your digestive function is compromised, we cannot fully benefit from the nutrients in our diet, no matter how high the quality of our foods.*

No Animal Byproducts - Plant Enzyme Digestive Formula contains no animal products. It is presented in a vegetable capsule and is suitable for vegetarians. It may be particularly useful for the improved digestion of plant foods like grains and beans, as well as dairy products, which commonly induce digestive upset. Strengthened digestion means we will harness more of the essential, life-building nutrients in the quality foods we choose.*

Comprehensive Formula - Plant Enzyme Digestive Formula includes support for digesting all three macronutrients, carbohydrates, proteins, and fats. It includes the carbohydrate-digesting enzymes - amylase, glucoamylase, cellulase, hemicellulase, diastase, beta-glucanase, and invertase. This product also contains lactase, for the digestion of lactose - the 'milk sugar' along with the protein-digesting enzymes - protease, acid protease, alpha-galactosidase, and protease SP.*

REQUIRED FOR THE PROPER ABSORPTION OF NUTRIENTS - Betaine HCl is an excellent source of hydrochloric acid, which is produced by the parietal cells of the stomach. Hydrochloric acid is required for the proper absorption of nutrients, including vitamin B12 and minerals such as calcium, magnesium, zinc, iron, and selenium. *

SUPPORT DIGESTIVE FUNCTION - Betaine HCl provides 750 mg betaine hydrochloride along with pepsin, a key protein digestive enzyme produced in the stomach. This product is ideal for those who are looking to support their stomachs digestive function. Taking one capsule before a meal aids digestion, especially the digestion of protein-containing foods, and supports the assimilation of nutrients. *

UPGRADED DELIVERY - This product was previously in a tablet form. However, we have upgraded to a capsule. This change ensures delivery of betaine HCl and pepsin to the stomach where they are needed to initiate digestion. *

True TG Form - Unlike many omega 3 fish oils, our TruTG Fish Oils are in the Triglyceride form (TG), the same form found in fish. TruTG may support superior bioavailability than the standard EE form.*

Enhanced Absorption & Digestive Tolerance - Manufactured using a proprietary emulsification technology that significantly reduces the size of fish oil molecules, resulting in enhanced absorption and easy digestion.*

Convenient & Kid Friendly - Ideal for children and those who do not prefer to swallow softgels. OmegAvail has the taste of a fruit smoothie without any oily texture. Quickly dissolves for easy mixing in water, juice, or blended beverages.*

SUPPORT FOR THE MODERN DIET - Over the years, high protein/low carbohydrate diets have become very popular. These types of diets are fast becoming lifestyle changes for many people. *

ASSISTS WITH THE DIGESTION OF PROTEIN - AllerGzyme is a full spectrum proteolytic enzyme complex that assists with the digestion of difficult-to-break-down proteins such as gluten, gliadin, and casein from whey and dairy, as well as many other protein sources in the diet, including soy and rice. *

POWERFUL KEY INGREDIENTS - Featuring Glutalytic endo & exo-peptidase complexes as well as bromelain, which expands the proteolytic effectiveness of these enzymes and contributes in supporting the digestive system.*

HOW EFFECTIVE ARE YOUR PROBIOTICS? - 60-70% of the organisms in our Probiotic Supreme DF survive the harsh stomach acids to reach the GI tract, vs. 4% for standard capsules.*

SUPERIOR, PATENTED DELIVERY - As the probiotics are meant to release over an extended time frame (10-12 hours), effective dosing need only take place once per day. This also ensures delivery throughout the entire intestinal tract.*

15 BILLION DAIRY-FREE CFU - Most probiotics contain dairy, making it difficult for those looking for powerful dairy-free supplementation. This is our dairy-free alternative, which offers 15 Billion CFU (colony-forming units) per caplet.*

SUPPORT YOUR GUT - L-Glutamine is an amino acid with a vast array of functions and health benefits, derived from its ability to feed various cells in the body. Glutamine is essential to the health of the immune system and the digestive tract. In the gut, it promotes the health and proper functioning of mucosal cells, which are necessary for normal healing and repair. *

THERAPEUTIC DOSE - L-Glutamine powder contains 3000 mg of L-Glutamine per 3/4 teaspoon. *

POWERFUL HEALTH EFFECTS - Glutamine, like all amino acids, contains nitrogen, which is needed by many cells throughout the body - including immune, gut and muscle cells. Nitrogen is also a building block for proteins, antioxidants, neurotransmitters and DNA. Glutamine has a unique Robin Hood-like nature - it distributes nitrogen freely to the cells which need it most, giving your body powerful and wide-ranging health effects. *

PANCREATIC ENZYMES & OX BILE - These pancreatic enzymes are nearly bioidentical to human enzymes and support protein, carbohydrate, and fat digestion. PaleoZyme also includes bromelain to promote protein digestion and ox bile to aid the emulsification of fats.*

ALLERGEN-FREE & PALEO COMPLIANT - Free of grain, legume, and dairy-sourced ingredients, making it ideal for those with sensitivities to these common foods/food groups and those who prefer to maintain a strict Paleo diet.*

DELAYED RELEASE - Enteric coating protects the enzymes from stomach acid. This helps preserve their activity for the first section of small intestine, where pancreatic enzymes are intended to function.*

Highest Potency 250 CFU - Featuring ten of the most highly-researched probiotic strains, with each strain and specific CFU count being fully disclosed. These strains are capable of surviving the harsh journey to the intestines, where they can support GI health & immune health.*

Superior Packaging Technology - This new, state-of-the-art, innovative package lining protects probiotics from damaging exposure to moisture, oxygen, and light to extend shelf life while eliminating the need for refrigeration.

Shelf Stable & Dairy Free - This novel packaging removes the need for refrigeration, making this dairy-free probiotic convenient for travelers and anyone on the go.

Convenient Probiotic Powder - Unflavored, powder-filled sticks that are easy to mix into liquids. Formulated with 5 billion CFUs per serving.

Seven Diverse, Researched Strains - Lactobacillus and Bifidobacterium probiotic bacteria strains, human milk oligosaccharides, and a digestive enzyme blend modeled after human breast milk constituents.

Add to Breast Milk, Formula, Milk or Juice - Mix one stick pack (1 gram) into breast milk, infant formula, milk or juice per day, or as directed by your health-care practitioner.

HERBAL DIGESTIVE BITTERS - Powerful blend of herbal bitters to support healthy digestion.* Combines ginger, fennel, dandelion, gentian, and lemon balm.

TARGET GAS & BLOATING - Designed to optimize healthy digestion and help reduce occasional gastrointestinal discomfort after meals, such as gas, bloating, and excessive fullness.*

ALTERNATIVE TO ALCOHOL-BASED LIQUIDS - Capsule form offers powerful digestive support without needing an alcohol-based delivery method.*