Best Paleo Digestive Supplements in 2026

COMPLETE SUPPORT. Complete Digestion is a comprehensive formula that contains gentle digestive enzyme blends to calm digestive complaints like occasional gas, bloating, and indigestion while also working to provide you with the nutrition and fuel you need to be at your best.*

HEALTHY DIGESTION SUPPORT. Complete Digestion is the ideal digestive enzyme supplement for those with mild to moderate discomfort or for those who want general digestive support.*

3 BENEFITS IN 1. This digestion supplement provides 3-in-1 support with a classic strength digestive enzyme blend, a hardy probiotic blend at 125 million CFU per capsule, and ATPro for energy promotion.*

HIGH POTENCY. Enzyme Defense Pro is Enzyme Science’s highest potency proteolytic formula. With Vitamin D3, L-lysine, and minerals, this unique, powerful enzyme formulation is designed to support and promote a healthy immune function.*

SUPPORTS IMMUNE FUNCTION. Nearly all environmental threats contain proteins that the immune system must identify and break down. Enzyme Defense contains proteolytic enzymes that help break down unwanted proteins and support the immune system, respiratory, and sinus health.* Additional enzymes are included to target and help break down excess mucus.*

HELPS PROMOTE CELLULAR REPAIR. Formulated within this immune system booster are proteolytic enzymes, also known as proteases, that help promote cellular repair & recovery and encourage a healthy physiological response.*

DIGESTIVE & GUT HEALTH: Enzymates Doggy Digestive Enzymes + Pumpkin offers a unique blend of enzymes, custom probiotics, brewer’s yeast and pumpkin for digestive and gastrointestinal health; our enzyme blend specifically formulated for dogs can provide relief from diarrhea, constipation, gas, bloating, and irritable bowels. and more as they help maintain healthy, balanced intestinal microflora, making vitamins and nutrients, and supporting the immune system

UNIQUE ENZYME FORMULA: Including Therablend, Formulated by the Enzyme experts at Enzymedica, this digestive supplement for dogs includes protease, to hydrolyze protein; Amylase, Glucoamylase, and Alpha-galactosidase to hydrolyze carbohydrates; Lipase, to hydrolyze fats; Cellulase, Pectinase, and Phytase to break down cellulose such as corn and wheat common in many popular pet foods.

SUPERFOOD BLEND: Special formula combines high fiber pumpkin and brewer’s yeast to soothe your pet’s upset stomach, helps maintain healthy, balanced intestinal microflora, supports nutrient absorption and the immune system.

Relieves discomfort associated with the digestion of fatty foods

Metabolism booster; Supports healthy fat metabolism and provides unparalleled gallbladder, pancreas and liver support

Cardiovascular and Circulatory Support; When taken on an empty stomach, enzymes promote whole body wellness

Digestive Booster: Speeds up digestion & improves energy to help unlock the power of your food to fuel your life

Fast Acting Relief: Enjoy the meal without discomfort; helps to eliminate occasional gas, bloating & indigestion

Complete Support: A comprehensive blend of 13 types of digestive enzymes to break down all the components of your meal, like fats, fiber, protein and carbohydrates

Digestive Booster: Speeds up digestion & improves energy to help unlock the power of your food to fuel your life

Fast Acting Relief: Enjoy the meal without discomfort; helps to eliminate occasional gas, bloating & indigestion

Complete Support: A comprehensive blend of 13 types of digestive enzymes to break down all the components of your meal, like fats, fiber, protein and carbohydrates

BALANCED FLORA. Supports vaginal and urinary health, naturally helping the body reduce occasional gas, bloating, & indigestion

MICROBIOME BOOSTER. Helps to sustain a healthy gut

3 BENEFITS IN 1 with Enzymes, Broccoli Seed Extract and 1 Billion CFU probiotics

HEALTHY AGING. Telomere Pro is a supplement formulated to encourage cellular rejuvenation and healthy aging, featuring a Telomerin blend that activates the Telomerase enzyme, the enzyme responsible for rebuilding telomeres.*

NATURALLY OCCURRING ENZYME. Telomerase is a naturally occurring enzyme that influences a cell’s ability to lengthen telomeres and prevent them from shortening.* Subject of a study published in Alternative Therapies in Health and Medicine.

FORMULATED WITH BOTANICALS. The botanicals used in Telomere Pro have been specifically formulated to positively influence telomerase.*

PHYSIOLOGICAL SUPPORT. Enzyme Science’s (PEA)+ supplement provides support for physiological stress or discomfort associated with occasional stiffness and compromised tissue function as a result of overexertion and everyday stress.*

ALL-NATURAL. Palmitoylethanolamide (PEA) is a clinically studied, natural ingredient from safflower seed. It has been utilized for decades and is available in dietary supplements worldwide as an option for the onset of physiological stress.*

SAFFLOWER + CURCUMIN. Enzyme Science’s (PEA)+ features a unique blend of PEA from safflower seed paired with the well-researched, patented, and highly bioavailable curcumin, Meriva Phytosome.

FOR MUSCLE & JOINT FUNCTION. Myomend consists of a high potency, therapeutic blend of enzymes, including nattokinase and serrapeptase. In combination with Rutin, this formula naturally accelerates muscle and tissue repair and provides optimal wellness.*

HEALTHY MUSCLE SUPPORT. MyoMend is the ideal enzyme supplement for recovery and muscle function after overexertion.*

CONTAINS PROTEOLYTIC ENZYMES. Proteolytic enzymes, also known as proteases, work systemically to help break down damaged proteins, speeding up recovery and promoting flexibility and mobility.*

FOR MUSCLE & JOINT FUNCTION. Myomend consists of a high potency, therapeutic blend of enzymes, including nattokinase and serrapeptase. In combination with Rutin, this formula naturally accelerates muscle and tissue repair and provides optimal wellness.

HEALTHY MUSCLE SUPPORT. MyoMend is the ideal enzyme supplement for recovery and muscle function after overexertion.

PHYSIOLOGICAL SUPPORT. Enzyme Science’s (PEA)+ supplement helps provide support for physiological stress or discomfort associated with occasional stiffness and compromised tissue function as a result of overexertion and everyday stress