Best K9 Advantix Dog Flea Drops in 2025

Contains one 2-pack of K9 Advantix II for Extra Large Dogs over 55lbs and one 2-pack of K9 Advantix II for Large Dogs 21-55 lbs. Do not use on cats.

K9 Advantix II 30-day treatment & prevention protects dogs from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

Contains one 6-pack, one 4-pack, and one 2-pack of K9 Advantix II for Extra Large Dogs over 55lbs. Do not use on cats.

K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die

K9 Advantix II Medium Dog 30-day treatment & prevention protects dogs 11-20 lbs. from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die

Contains one 6-pack of K9 Advantix II for Small Dogs 4-10 lbs and one 2-pack of K9 Advantix II for Small Dogs 4-10 lbs

K9 Advantix II Small Dog 30-day treatment & prevention protects dogs 4-10 lbs. from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

Contains one 6-pack of K9 Advantix II for Medium Dogs 11-20 lbs and one 2-pack of K9 Advantix II for Medium Dogs 11-20 lbs

K9 Advantix II Medium Dog 30-day treatment & prevention protects dogs 11-20 lbs. from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

Vet recommended flea treatment and prevention for dogs at weighing 21 to 55 lbs., at least 7 weeks of age

Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment

Same-day effectiveness, kills fleas within 12 hours of application and keeps working for 30 days

BREAK THE FLEA LIFE CYCLE: Effectively breaks the flea life-cycle by killing all life stages of fleas: adults, eggs and larvae

ACTIVE INGREDIENTS THAT WORK: Contains the same active ingredients as Bayer K9 Advantix II for Dogs (pyriproxyfen & imidacloprid)

FLEA TREATMENT FOR DOGS: Kills fleas and lice within 12 hours of drops application, and prevents reinfestations for up to 4 months

Vet recommended flea treatment and prevention for dogs at weighing 3 to 10 lbs., at least 7 weeks of age

Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment

Same-day effectiveness, kills fleas within 12 hours of application and keeps working for 30 days

For dogs 7 weeks of age and older weighing 55 lbs and over.

K9 Advantix provides protection from more biting pests than the leading competitor.

It not only kills ticks, fleas and mosquitoes, it also repels them!

KILLS FLEAS AT ALL LIFE STAGES: Breaks the flea life cycle by killing all stages of fleas: Eggs, Larvae, and Adults. This provides a well-rounded flea treatment for dogs.

SAME EFFECTIVENESS AS THE LEADING BRAND: The SAME amount of the SAME active ingredients delivering the SAME dog flea and tick control for a lot LESS!

WATERPROOF: ZoGuard Plus for Dogs is waterproof and will remain effective even after bathing, water immersion, or exposure to sunlight. It is a great dog flea and tick treatment option for even the most active dogs.

EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Max is a fully waterproof, flea & tick topical prevention for dogs that kills and repels fleas, ticks, and mosquitoes for up to 30 days after application.

TRUSTED, VET QUALITY FORMULA: Containing the same active ingredients as K9 Advantix II for Dogs, PetArmor Max for Dogs has a powerful formula that kills fleas within 12 hours.

BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may only kill adult fleas, PetArmor Max Dog Flea Treatment works by breaking the flea life cycle. Kills flea eggs and larvae for up to 4 weeks

BREAK THE FLEA LIFE CYCLE: Effectively breaks the flea life-cycle by killing all life stages of fleas: adults, eggs and larvae

ACTIVE INGREDIENTS THAT WORK: Contains the same active ingredients as Bayer K9 Advantix II for Dogs (pyriproxyfen & imidacloprid)

FLEA TREATMENT FOR DOGS: Kills fleas and lice within 12 hours of drops application, and prevents reinfestations for up to 4 months

Kills ALL flea life stages, including eggs

Kills ALL flea life stages, including eggs

Prevents fleas on treated dogs from infesting your home

Kills fleas within 12 hours of application

EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Max is a fully waterproof, flea & tick topical prevention for dogs that kills and repels fleas, ticks, and mosquitoes for up to 30 days after application.

TRUSTED, VET QUALITY FORMULA: Containing the same active ingredients as K9 Advantix II for Dogs, PetArmor Max for Dogs has a powerful formula that kills fleas within 12 hours.

BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may only kill adult fleas, PetArmor Max Dog Flea Treatment works by breaking the flea life cycle. Kills flea eggs and larvae for up to 4 weeks

COMPARE TO K9 ADVANTIX II: Activate II uses Imidacloprid, Permethrin, and Pyriproxyfen - the same safe, fast acting active ingredients used in Advantix II for Dogs. Includes 8 monthly doses

ACTIVELY PROTECTS YOUR DOG: Activate II is approved by veterinarians to repel and kill fleas and ticks on contact - before your dog is exposed to bites and potential flea borne illnesses

STOP INFESTATIONS FAST: Our topical drops prevent infestations by breaking the flea life cycle - our insect growth regulator (IGR) starts killing flea eggs and larvae within 12 hours of application

LONG-LASTING WATERPROOF PROTECTION: PetArmor Max for dogs is a waterproof, flea & tick topical prevention for dogs that kills and repels fleas, ticks, and mosquitoes for up to 30 days.

CONTAINS THE SAME ACTIVE INGREDIENTS AS K9 ADVANTIX II FOR DOGS: Get an affordable, powerful, vet-quality formula that kills fleas within 12 hours.

BREAK THE FLEA LIFE-CYCLE: PetArmor Max dog flea treatment works by killing adult fleas and preventing flea eggs and larvae from maturing for up to 4 weeks.

Contains one 6-pack of K9 Advantix II flea and tick prevention for large dogs 21-55 lbs, PLUS one 60-count pack of Synovi G4 joint supplement for dogs of all ages, sizes and breeds

K9 ADVANTIX II: Vet recommended, easy-to-apply monthly topical that kills and repels fleas, ticks and mosquitoes; kills through contact, no biting required. Do not use on cats

SYNOVI G4: Poultry-flavored, easy-to-give chew that features a unique combination of ingredients that assist with joint health, muscle tone and antioxidant function; promotes healthy hips and joints for everyday mobility in dogs

LONG-LASTING PROTECTION: Sergeant’s Guardian Topical is a flea and tick prevention for dogs that kills fleas and ticks plus repels moquitoes for up to 4 weeks.

AFFORDABLE FLEA & TICK TREATMENT: Sergeant’s Guardian Flea and Tick is an affordable way to protect your dog from fleas, ticks and mosquitoes.

QUICK-DRYING FORMULA: Sergeant's Guardian is quick drying flea and tick medication that is specially formulated for dogs over 12 weeks.

Kills adult fleas, eggs and larvae

Packaging may vary

Remains effective even after swimming or shampooing

K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die

K9 Advantix II Medium Dog 30-day treatment & prevention protects dogs 11-20 lbs. from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die

Contains one 6-pack of K9 Advantix II Flea and Tick Prevention for Small Dogs 4-10 lbs, PLUS one 60-count pack of Synovi G4 joint supplement for dogs of all ages, sizes and breeds

K9 ADVANTIX II: Vet recommended, easy-to-apply monthly topical that kills and repels fleas, ticks and mosquitoes; kills through contact, no biting required. Do not use on cats

SYNOVI G4: Poultry-flavored, easy-to-give chew that features a unique combination of ingredients that assist with joint health, muscle tone and antioxidant function; promotes healthy hips and joints for everyday mobility in dogs

Contains and one 6-pack of K9 Advantix II flea and tick prevention for small dogs (4-10 lbs) and one 60-count bottle of Free Form snip tip fish oil supplements for small dogs and cats

K9 ADVANTIX II: K9 Advantix II flea and tick prevention provides 30 days of protection from fleas, ticks, and mosquitoes. Easy to apply topical formula that starts working to kill fleas within 12 hours of application.

FREE FORM SNIP TIPS: Highly-concentrated, liquid-filled capsules of Omega-3 fatty acids that support overall health and wellness for sensitive skin, eye, joint, brain, heart and kidney health

K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die

K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die