Best 90 Pounds And Above Dog Flea Drops in 2026

Waterproof flea and tick treatment for dogs: Frontline Plus for Dogs provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your dog. This product is approved for use on dogs 23-44 lbs.

Break the flea life cycle with frontline: Frontline flea and tick treatment for dogs kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations.

Kills fleas and ticks: Frontline flea and tick treatment for dogs kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease.

K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice

Kills fleas within 12 hours of application

Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die

EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a waterproof, flea & tick topical prevention for dogs that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.

TRUSTED, VET QUALITY FORMULA: Containing fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs. PetArmor Plus for Dogs has a powerful formula that starts to kill fleas within 24 hours.

BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by effectively breaking the flea life cycle. Kill flea eggs and larvae to prevent re-infestation.

COMPARE TO K9 ADVANTIX II: Activate II uses Imidacloprid, Permethrin, and Pyriproxyfen - the same safe, fast acting active ingredients used in Advantix II for Dogs. Includes four (4) monthly doses

ACTIVELY PROTECTS YOUR DOG: Activate II is approved by veterinarians to repel and kill fleas and ticks on contact - before your dog is exposed to bites and potential flea borne illnesses

STOP INFESTATIONS FAST: Our topical drops prevent infestations by breaking the flea life cycle - our insect growth regulator (IGR) starts killing flea eggs and larvae within 12 hours of application

Same product, new look - This product is identical in manufacturing and formulation as the Solimo brand

One 3 dose pack of Amazon Basics Flea and Tick Treatment for Dogs, Small (5-22 lbs), 3 Count (Previously Solimo)

Amazon Basics Flea & Tick starts eliminating fleas and ticks within 24 hours of treatment

Vet recommended flea treatment and prevention for dogs at weighing over 55 lbs., at least 7 weeks of age

Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment

Same-day effectiveness, kills fleas within 12 hours of application and keeps working for 30 days

The patented and easy-to-use Pro-Glide angled applicator with rounded edges easily gets through dog's fur, for gentle on-skin application. Suitable for long and short-haired dogs

Includes 3 monthly treatments in easy to apply, single dose tubes

Topical drop formula kills fleas, flea eggs, flea larvae, brown dog and deer ticks, prevents re-infestation, plus repels mosquitoes for 30 days

KILLS FLEAS AT ALL LIFE STAGES: Breaks the flea life cycle by killing all stages of fleas: Eggs, Larvae, and Adults. This provides a well-rounded flea treatment for dogs.

SAME EFFECTIVENESS AS THE LEADING BRAND: The SAME amount of the SAME active ingredients delivering the SAME dog flea and tick control for a lot LESS!

WATERPROOF: ZoGuard Plus for Dogs is waterproof and will remain effective even after bathing, water immersion, or exposure to sunlight. It is a great dog flea and tick treatment option for even the most active dogs.

Kills fleas, ticks, eggs, larve, and chewing lice

Can be used on puppies and kittens eight weeks and older

Can be used on breeding, pregnant, and lactating dogs

EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Max is a fully waterproof, flea & tick topical prevention for dogs that kills and repels fleas, ticks, and mosquitoes for up to 30 days after application.

TRUSTED, VET QUALITY FORMULA: Containing the same active ingredients as K9 Advantix II for Dogs, PetArmor Max for Dogs has a powerful formula that kills fleas within 12 hours.

BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may only kill adult fleas, PetArmor Max Dog Flea Treatment works by breaking the flea life cycle. Kills flea eggs and larvae for up to 4 weeks

BREAK THE FLEA LIFE CYCLE: Effectively breaks the flea life-cycle by killing all life stages of fleas: adults, eggs and larvae

ACTIVE INGREDIENTS THAT WORK: Contains the same active ingredients as Bayer K9 Advantix II for Dogs (pyriproxyfen & imidacloprid)

FLEA TREATMENT FOR DOGS: Kills fleas and lice within 12 hours of drops application, and prevents reinfestations for up to 4 months

SAFE & EFFECTIVE: Kills and repels fleas and ticks by contact for up to one month for large dogs over 40 lbs and 12 weeks or older.

EASY APPLICATION: Simply use the supplied dropper applicator and squeeze the specified amount betweeh the shoulder blades and base of the tail.

NATURAL FORMULA: Made with a unique blend of certified natural oils like Clove, Thyme and Cinnamon oils.

A Natural Flea + Tick Defense - These delicious hickory bacon flavored soft chews promote the body's natural response to ward off fleas, ticks and mites. These soft chews have been vet-reviewed and formulated by experts using natural ingredients like coconut oil, flaxseed, garlic and brewer's yeast (all within the safe limits for dogs) to provide safe defense for your dog!

Builds Daily + Long-Term Resistance When Given Every Day - 100% safe levels of natural ingredients like coconut oil, garlic, B vitamins and omegas help build up internal resistance to seasonal pests in your dog's body. These ingredients also have the added benefit of supporting your dog's skin, joint and immune health with omega-3's that help promote a healthy inflammatory response.

Easier + Less Mess Than Oils, Sprays and Collars - These soft chews have a delicious hickory bacon flavor that your dog will love.1-3 treats a day (depending on your dog's weight) will not only help provide additional protection against pests but will also help support joint, skin and immune health with the added omegas and vitamins. Please consult with your vet first before stopping any medication.

4X PROTECTION FOR ACTIVE DOGS: Topical formula destroys fleas, flea eggs, ticks, lice, and even mosquitos on contact

POWERFUL, LONG-LASTING PREVENTION: Prevent mosquito or tick bites and lice or flea infestations with a single application per month

THE OUTDOORSMAN’S CHOICE: Waterproof treatment drops offer protection through the harshest conditions of wind, sun, or even heavy rain

✅ FLEA & TICK PREVENTION: revolution flea & tick chewables treats provides daily protection and control for your dog, against fleas, ticks, eggs, larvae, mosquito.

✅ NATURAL & DELICIOUS & SAFE: the bio soft chews made with only natural and safe ingredients and it’s really tasty bacon flavor for dogs.

✅ BEST REPLACEMENT FOR COLLAR, DROPS, SPRAYS, SHAMPOO: Just give some chews your dog daily to protect from flee and ticks. RECOMMENDED SERVING PER DAY: up to 10 LB - single dose, 10-22lbs - 2 meds chews, 31-60 LB - 3 capsules, large 61-90 LB - 4 pill, 90 - 110 lbs - 5 tabs.

From the #1 Name in Flea and Tick Protection* *Data on file at Boehringer Ingelheim.

Easy to use flea and tick protection for dogs

Kills adult fleas, flea larvae, flea eggs and ticks

🐾FLEA AND TICK PREVENTION FOR DOGS: Get dog flea & tick control all year. Tasty bacon-flavored flea treatment dogs love to eat. A safer all-natural alternative supplement to flea medicine for dogs.

🐾MADE IN THE USA: Our dog flea & tick control chews are a careful blend of natural ingredients that help maintain dog flea & tick control but also support overall dog wellness. Fleas will flee!

🐾ADDED VITAMINS: Besides helping offer dog flea and tick treatment chewable protection against annoying fleas & ticks, Vitamins B1+B6+B12 help stimulate healthy growth, immune system & digestion.

- Advanced Technology: The sound wave produced by the device has a frequency range of 19.5-135 kHz and can cover an area of around 64 square feet.

- Safe for Humans and Pets: The device emits a high-frequency sound that can safeguard your pet and their sleeping areas from pests in a manner that is completely safe, odor-free, and free of any harmful chemicals.

- Rechargeable: This innovative device comes with a Rechargeable battery that lasts approximately six months.