Best Doctors Best Enzyme Supplements in 2026

Daisy
Last Updated: Feb 11, 2026

At a Glance: Our Top Picks for Doctors Best Enzyme Supplements

NOW Supplements, Magnesium Citrate, Enzyme Function*, Nervous System Support*, 120 Veg Capsules
#TOP1
Now Supplements, Magnesium Citrate, Enzyme Function*, Nervous System
9.9
PM SCORE
Doctor's Best Natto-Serra, Non-GMO, Vegan, Gluten Free, 90 Veggie Caps
#TOP2
Doctor's Best Natto-Serra, Non-Gmo, Vegan, Gluten Free, 90
9.8
PM SCORE
Doctor's Best Stabilized R-Lipoic Acid with BioEnhanced Na-RALA, 100 mg, 60 Veggie Caps
#TOP3
Doctor's Best Stabilized R-Lipoic Acid With Bioenhanced Na-Rala,
9.8
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Doctors Best Enzyme Supplements of 2026

Now Supplements, Magnesium Citrate, Enzyme Function*, Nervous System Support*, 120 Veg Capsules

NOW
1294
2.63 X 2.63 X 4.75 Inches
0.35 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Best~Naturals 9.88

Features

SUPPORTS ENERGY PRODUCTION: Magnesium is a mineral that is critical for energy production and metabolism, muscle contraction, nerve impulse transmission, and bone mineralization.

CRITICAL FOR ENZYME FUNCTION: It is a required cofactor for an estimated 300 enzymes. Among the reactions catalyzed by these enzymes are fatty acid synthesis, protein synthesis, and glucose metabolism.

CLASSIFICATIONS/CERTIFICATIONS: Kosher, vegan, soy free, keto friendly, Non-GMO, halal

GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the now manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).

Packaged in the USA by a family owned and operated company since 1968.

During the summer months products may arrive warm, but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

Doctor's Best Natto-Serra, Non-Gmo, Vegan, Gluten Free, 90 Veggie Caps

DOCTOR'S BEST
DRB-00294
2.13 X 2.13 X 3.75 Inches
0.14 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Promotes and maintains healthy sinus and airway function

Helps maintain blood pressure already in the normal range

Supports healthy immune response and supports healthy circulation

Gluten Free, Non-GMO, Vegetarian

Label images may vary

Contains Soy

During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

Doctor's Best Stabilized R-Lipoic Acid With Bioenhanced Na-Rala, 100 Mg, 60 Veggie Caps

DOCTOR'S BEST
DRB-00123
2.13 X 2.13 X 3.69 Inches
0.09 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

DOCTOR’S BEST STABILIZED R-LIPOIC ACID CONTAINS BIOENHANCED NA-RALA - the sodium salt of R-Lipoic acid (RLA). BioEnhanced Na-RALA is in its natural and stabilized form of RLA that won’t degrade at high temperatures, and is more bioavailable and biologically active. Lipoic acid (LA) plays an important role in glucose metabolism and energy production. LA is both fat and water soluble. D-Biotin is an integral part of enzyme activity necessary for the breakdown and conversion of fatty acids and carbohydrates into energy.

POWERFUL ANTIOXIDANT – Lipoic acid is a potent antioxidant that supports mitochondrial function, helps protect against oxidative stress and maintains cellular energy. Supports nerve health, glucose metabolism and cardiovascular health.

CELLULAR ENERGY - R-lipoic acid is made by the body in our mitochondria, the cells that provide energy. Protecting mitochondria from free radicals, R-Lipoic Acid supports energy at the cellular level.

BETTER ABSORPTION - R-Lipoic Acids includes the active “R” form of lipoic acid, stable and easier for the body to absorb. Improved stability from this formula is the cause for better absorption and bioavailability.

During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

Source Naturals Ultra-Mag High-Efficiency Magnesium Complex - Maintains Muscle & Nerve Function - 240 Tablets

SOURCE NATURALS
SN0033
5.60 X 3.00 X 3.00 Inches
1.05 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Health Chest 9.96

Features

SUPPORTS CARDIOVASCULAR HEALTH. Research suggests that healthy homecysteine levels play a role in cardiovascular health. Enzymes support healthy homocysteine levels in the blood and many are dependent on vitamin B-6.

ULTRA-MAG BENEFITS. Ultra-Mag uses a complex blend of highly bioactive forms of magnesium—citrate, taurinate, malate, glycinate and succinate— to provide all of the benefits that magnesium offers. In addition to supplying 100 percent of the body’s daily magnesium needs, our formula includes vitamin B-6 to further support cardiovascular health.

ABOUT SOURCE NATURALS ULTRA MAG. Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, preservatives, or artificial color, flavor or fragrance.

TRUSTED FOR OVER 35 YEARS. Source Naturals was created in 1982 by CEO Ira Goldberg to support each individual's potential to enjoy optimal health.

MANUFACTURED IN THE USA. Our facility is located in Scotts Valley California.

#TOP5

Doctor's Best Serrapeptase, Non-Gmo, Gluten Free, Vegan, Supports Healthy Sinuses, 40,000 Spu, 270 Count (Pack Of 1)

DOCTOR'S BEST
DRB-00190
2.63 X 2.63 X 5.06 Inches
0.40 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Root Summit 9.53

Features

DOCTOR’S BEST SERRAPEPTASE 40,000 SPU - Formulated with Serrateric, a superior alternative to enteric coating that protects the serrapeptase enzyme until it reaches the intestine for optimal absorption.

Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery

BEST SERRAPEPTASE ENZYME SUPPLEMENT - Serrapeptase is a powerful proteolytic enzyme derived from the bacteria found in the intestine of silkworms.

SUPPORT HEALTHY SINUSES & IMMUNE SYSTEM – Helps support healthy respiratory and sinus function. Helps support muscle joint and overall tissue health. Helps transport mucus in t

HIGH POTENCY - Serrapeptase (serratio-peptidase) is a protein-digesting enzyme isolated from the friendly bacterium Serratia E-15 discovered in the Japanese silkworm and has been used as a nutritional supplement in Europe and Asia for over three decades.

OPTIMAL ABSORPTION - Each vegetarian capsule of Doctor’s Best Serrapeptase contains pure serrapeptase designed for optimal absorption in the intestinal tract.

During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

Enzymedica Digest Gold + Probiotics, 2-In-1 Advanced Formula, Supports Healthy Gut With 9 Different Probiotic Strains, Improves Digestion, 45 Capsules (Ffp)

ENZYMEDICA
29110-FFP
2.00 X 2.00 X 3.63 Inches
0.10 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
NetRush 9.98

Features

Advanced 2-in-1 digestive support: Combines Digest Gold with 1.5 billion active probiotic cultures to help relieve occasional bloating, gas, and irregularity, while supporting a healthy microbiome

Speeds up digestion: When you feel bloated and heavy (no matter what you eat), this enzyme blend helps break down food more quickly while promoting a healthy microflora so digestion works smoothly

Most advanced support: One capsule with every meal provides powerful enzymes to digest proteins, carbohydrates, dairy, fats, and fibers – even for your largest meals

Powered by Thera-blend: Our Thera-blend enzymes are formulated for optimal activity in the digestive system (and all the pH levels found within), for better digestion every time

Purity promise: Contains no gluten, milk, casein, soy, egg, artificial colors, flavors, or GMOs

#TOP7

Doctor's Best Same -- 200 Mg - 60 Enteric Coated Tabs

DOCTOR'S BEST
753950002067
0.00 X 0.00 X 0.00 Inches
0.15 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Swanson Health Products 9.96

Features

Our SAMe 200 contains 200 mg of active SAMe in each tablet

Doctor's Best

Swanson Dr. Stephen Langer's Formula - Natural Probiotic W/Prebiotic Fos - 16-Strain Supplement Promoting Digestive Support W/ 3.2 Billion Cfu Per Capsule - (60 Veggie Capsules) 3 Pack

SWANSON
1.90 X 1.90 X 3.50 Inches
0.10 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Swanson Health Products 9.96

Features

PROMOTES DIGESTIVE HEALTH: Featuring probiotic FOS, Swanson's Dr. Stephen Langer formula is specially formulated with diverse strains to promote digestion, gut health, and immune support using ingredients you can trust.

POWERFUL FORMULA: Our natural digestive supplement features 16 strains of probiotics — almost 4x the strains of other popular formulations — with 3.5 billion CFUs per capsule, supporting comprehensive probiotic nourishment.

DOSAGE INSTRUCTIONS: Our wellness supplements offer everyday solutions for an enhanced mind, body, and home using only the purest ingredients. For best results, take one veggie capsule per day with water or juice.

OUR QUALITY COMMITMENT: For nearly 50 years, Swanson has delivered science-backed health products worldwide. Each wellness supplement is made in our GMP certified facilities, and our purity and potency testing includes independent third-party labs.

MONEY BACK GUARANTEE: At Swanson, we guarantee that every health product is made from the purest, freshest ingredients. If you aren't satisfied with any product(s) purchased within the last 30 days, return the unused portion to us for a full refund.

Top 10 enzyme supplements doctors best Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Doctor's Best 4
Enzymedica 1
Now 1
Source Naturals 1
Swanson 1

Top 10 enzyme supplements doctors best Brands Pie Chart


We've carried out a comprehensive analysis of 16,001 reviews on enzyme supplements doctors best, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select enzyme supplements doctors best priced around $26.32, with top brands including dr. berg nutritionals, garden of life, pure encapsulations, microbiome labs, dr. mercola, doctor's best, enzymedica, swanson and micrazym and amy myers md

Our team of expert editors reviewed these high-quality items and handpicked the top 8 enzyme supplements doctors best for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include dr. berg products, amazon.com, pattern., sportingdoc, dr. mercola, planet healthy 101, root summit, netrush and swanson health products and avva pharma .

We are dedicated to assisting our users in finding the right supplements Products based on their needs, saving them considerable time when choosing which enzyme supplements doctors best to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.