Best Papain Enzyme Supplements in 2026

Complex containing 9 digestive enzymes per serving (2 capsules) including bromelain and papain, Supports Healthy Digestion*

Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery

180 capsules, a 1-3 month supply (taken daily at listed serving size)

Healthy Break Down: Formulated to help digest & absorb proteins, fats & carbohydrates

Pancreatin 4x: Strong support w/ 17,500 units protease & amylase and 1,400 units lipase activity

Plant Power: Includes papain from papaya, peppermint leaf, ginger root, bromelain, aloe vera & more

Supporting your digestive health just got easier with Papaya Digestive Support; These digestive enzymes help break down food and support the absorption of nutrients

Formulated with a careful blend of digestive enzymes including papain, protease, alpha amylase and papaya

Simply chew 4 wafers after each meal, up to 3 times a day for increased digestive support; Our delicious chewable wafers are flavored with natural papaya and pineapple fruit

THE CLINICALLY STUDIED FORMULA: First introduced in Germany over 40 years ago, the Wobenzym N formula includes pancreatin protease, papain, bromelain, trypsin, chymotrypsin, rutoside trihydrate to help maintain healthy joints, mobility and flexibility

A TRADITION OF SUCCESS: Wobenzym N is a global leader in joint health and is the only systemic enzyme formula backed by decades of clinical research & customer satisfaction; Systemic enzymes work throughout the entire body to support overall joint health

HELPS IMPROVE JOINT COMFORT AND RANGE OF MOTION: Get going with Wobenzym N, the authentic systemic enzyme formula trusted by millions worldwide to provide clinically demonstrated support for joint & tendon health; For speedy recovery following exertion

A Natural Digestive Aid; Contains freshly ripened papaya fruit with papain, amylase & protease enzymes, which aid in the digestion of proteins and carbohydrates

Promotes Nutrient Absorption; Ideal after meals to aid in nutrient absorption and support digestive health; Chewable enzyme blend

Convenient & Delicious; Take these great-tasting, naturally-sourced papaya enzyme chewables after any meal to promote gastrointestinal wellness

Say Ta-Ta to Tummy Trouble: May help reduce the occasional incidence of heartburn & indigestion

Healthy Digestion: Plant enzymes Lipase, Cellulase, Amylase, Papain & Bromelain w/ papaya & calcium

Deliciously Convenient: Great-tasting citrus chewables perfect for before & after meals

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PROBIOTIC MULTI-ENZYME COMPLEX: Formulated with crucial probiotic strains and multiple food enzymes, MAV Nutrition’s Digestive Enzymes complex is designed to support digestion, ease gas and bloating, and increase nutrient absorption.*

BLOATING & GAS RELIEF: Beat the bloat! This powerful blend of essential enzymes like Lactase, Bromelain, Papain, Protease, and more provides digestive support and relief for gas and bloat after eating.

WITH 3 STRAINS OF LACTOBACILLUS: Our Digestive Enzymes are formulated with 3 potent strains of Lactobacillus probiotics to support optimal digestion and a healthy gut biome.*

Digestive Enzymes Supplement: Our enzyme formula helps with hard to digest food. Each enzyme is specialized to break down specific compounds in proteins, fats, dairy, gluten, and carbs.

Essential Enzymes for Enhanced Nutrient Absorption: A comprehensive blend with 18 plant-based enzymes for digestion including Amylase, Lipase, Bromelain, Lactase, Papain, Protease, Cellulase, Invertase, Glucoamylase, & more.

Gas and Bloating Relief: Take 1 capsule, 1 to 2 times daily, preferably at the beginning of a meal to help replenish enzymes and minimize digestive discomfort.

BREAKS DOWN FATS, CARBS, AND PROTEIN: Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion*

OPTIMIZES NUTRIENT AVAILABILITY: Formulated with bromelain, ox bile, pancreatin, and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates, and protein*

EASY TO SWALLOW TABLET: Supports healthy digestion!*

OPTIMIZES THE NUTRITIONAL VALUE OF FOODS*: A potent proprietary combination of digestive enzymes produced through controlled fermentation of select microbial species and is stable throughout the pH range of the GI tract.*

FULL SPECTRUM ENZYME FORMULA: This full-spectrum digestive support formula helps to optimize nutrient absorption by assisting in the breakdown of protein, carbohydrate, and fat, as well as dairy, grains, and indigestible fibers found in foods such as vegetables and beans.*

VEGAN: In addition, Digest Ultimate is suitable for vegetarians

Healthy Digestion – Sunshine Naturals Super-Digestive is a comprehensive blend of digestive enzymes, ox Bile, and activated Charcoal that promotes healthy digestion. Your body naturally produces a range of digestive enzymes and supplementing your body's natural production with these enzymes may promote digestive health.

Digest Fats, Carbs, And Proteins – Formulated with ox bile, betaine HCl, activated charcoal, pancreatin, pepsin, mycozyme, lipase, and papain, Sunshine Naturals Super-Digestive helps boost the breakdown of fats, proteins, and carbohydrates and enhance the nutrient absorption in your gut. Our formula has been developed for people experiencing digestive distress, slow digestion, and intestinal gas.

Most Effective Formula – Super-Digestive is the most effective enzyme formula on the market, containing protein, fat, carbohydrate, and fiber digestion enzymes. The digestive enzymes protect against cramps, flatulence, heartburn, belching, and reflux. Digestive enzymes supported by ox bile break down indigestible types of fiber that produce gas or bloating. Helps to manage regular bowel movements by encouraging metabolism, which relieves constipation and diarrhea symptoms.

This powder is made from the mature green papaya which contains the highest sources of papain and chymopapain

Royal Tropics

SUPPORTS HEALTHY INFLAMMATION PROCESSES: Intenzyme Forte is a potent source of enzymes that are an effective combination to break down proteins associated with inflammation.

PROMOTES MUSCULAR RELAXATION AND COMFORT: Muscles grow sore from overexertion. Proteolytic enzymes are an outstanding and highly effective source for supporting muscular relaxation.

SUPPORTS HEALTHY DIGESTION: Intenzyme Forte is a broad-spectrum nutrition supplement that supports pathways of protein metabolism, hormone processing, healthy circulation system support and healthy digestion. If taken on an empty stomach, Intenzyme Forte will work as a digestive aid.

ADVANCED ENZYME FORMULA: No more fearing food intolerance and avoiding certain foods, this complete multi enzyme complex digest proteins, carbs, fats, sugars, wheat, dairy, grains, gluten, lactose and more, for a better digestion

BROAD SPECTRUM BLEND: A digestive relief formula that breaks down unwanted wastes such as toxins, cellular debris and undigested proteins. Helps relieve inflammatory bowel discomfort, IBS, bloating and gas with the combination of ingredients such as protease, bromelain and papain

NATURAL PREBIOTIC & PROBIOTIC BALANCE: Offering beneficial gut flora for a healthy digestion & immune system; 18 critical enzymes: amylase, lipase, lactase & many more, supporting natural intestinal flora and nutrient absorption

Digestive Support: Pancreatic enzyme blend specially formulated for digestive support.*

Bioactive Formula: Bilex is a enzyme formula with pancreatin and papain for proper protein, carbohydrate, and digestion, along with the addition of ox bile extract to help break down and assimilate lipids in the intestinal tract.*

Digestive: supplement formulated to support G.I. health and its highly complex ecosystem.*

Nutritionally Supports Your Body's Natural Response to Inflammation, immune function, and Supports Digestive and Intestinal Health*

Contains Bromelain, Lipase, Trypsin, Papain, Pancreatin, Chymotrypsin, Protease, and Amylase

Bromelain and Proteolytic Enzymes to help support the breakdown of proteins in digestion, immune function, and other vital processes.*

Enteric Coated Advanced Delivery Method: Vitalzym high potency gel caps are unlike any tablet or powder based enzyme product available on the market today. Our formula contains no gluten, yeast or dairy and is designed to ensure maximum absorption into the bloodstream where it is then dispersed via your circulatory system throughout your body

Ingredients: Vitalzym Extra Strength premium softgels are the original, all-natural, vegetarian multi enzyme complex. Vitalzym was designed using a scientific research process to identify nature’s miracle ingredients that include Serrapeptase, Bromelain, Papain, Rutin, Amylase, Protease, Lipase and Amla Extract

Protect Your Health: Living well in modern times can be stressful and a source of pain at times. Vitalzym contains the most effective, purified vegan-based enzyme blend to promote healing, human bodily functions and leave you feeling clear and fresh

ORGANIC PAPAYA ENZYME CAPSULES - This Fresh Organic Papaya powder is made in the USA and certified USDA Organic & OU Kosher. The capsules are veggie caps and are Vegan and Non GMO herbal supplements.

NATURAL PAPAIN ENZYMES FROM PAPAYA - Papaya supplements are a great source of vitamin A, B, C, and K and is known as an excellent immunity supporter. It is a Super Fruit that is great for the support of hair and skin. A few papaya Capsules per day could provide you double your daily requirement of vitamins.

PAPAYA POWDER IS HIGH IN FIBER - Pure & Organic Papaya Capsules of papaya powder is often recommended as a natural home remedy for digestion related issues. This Organic Papaya is sugar free, high in fiber, and high in water content, both of which help to support constipation and promote a smooth bowel movement.

SUPPORTS JOINT HEALTH, COMFORT AND FLEXIBILITY: Each capsule of Heal-n-Soothe contains a blend of Proteolytic Enzymes, Turmeric Extract, Bromelain, Boswellia Extract, Papain, Rutin, Mojave Yucca Root, Devil's Claw, Citrus Bioflavonoids, Alpha Lipoic Acid and Ginger supplement.

SCIENTIFICALLY FORMULATED PROTEOLYTIC ENZYMES TO SUPPORT A HEALTHY IMMUNE SYSTEM: Heal-n-Soothe is formulated to be a strong and high potency proteolytic enzyme formulation.

BETTER THAN ORDINARY TURMERIC CURCUMIN SUPPLEMENTS: Yes, Heal-n-Soothe contains 60mg of turmeric, a widely recognized antioxidant. But we didn't stop there. Heal-n-Soothe also contains 12 more natural ingredients, designed to deliver maximum natural joint support.

100% Vegetarian product made using natural ingredients.

Strongest Formula with 500mg Carica Papaya Fruit and Leaf Extract in every dose.

Helps Increasing platelet and RBC counts. Promotes immunity

PROMOTES BETTER DIGESTION, , HELPS PREVENT BLOATING AND GI DISCOMFORT- well digestion allows our body to receive nutrients from food properly. Papaya contains special digestive health enzymes called papain which helps release vital nutrients into the body, supports and promotes maximum digestion of fats, carbohydrates, proteins, cellulose and fiber. Hence our Natural Papaya enzymes help optimize digestion and alleviate gastrointestinal discomfort.

FORMULATION OF PAPAYA WITH ALL-NATURAL CONTENTS FOR OPTIMUM RESULTS- Papaya is naturally high in multiple vitamins, minerals, and flavonoids. Known as the “fruit of the angels” because of its luscious flavor, it has been used for decades to promote your digestion. Our formulation of Natural Papaya contains 100% natural health enzymes such protease, amylase lipase, bromelain and papain for an overall optimal digestive support making it an ideal supplement for all!

BPA FREE, RECYCLABLE GLASS BOTTLES- Cheap plastic bottles are harmful to your health. We seal your supplements in amber glass bottles with heat-sealed sleeves and best by dates to ensure the safest and purest product available. Unlike some other supplement manufacturers, our bottles are fully recyclable. Each bottle contains 90 tablets that are easy to swallow, Gluten Free and Vegetarian.

❤️ ️ #1 RECOMMENDED ENZYME SUPPLEMENT FOR MEN & WOMEN - Enzyme +7 helps aid with acid reflux and also reduces gas and bloating.

❤️ ️BEST DIGESTIVE ENZYME - HELPS TO PROCESS DIFFICULT TO DIGEST FOODS - NO MORE ACID REFLUX,AND IMPROVE INDIGESTION: All you need to do is take 1 tablet 10 minutes before each meal.

❤️ ️ IMPROVE HOW YOU DIGEST NUTRIENTS NOW - This enzymatic formula is the ultimate aid that boosts the body's ability to digest fats, fiber, protein and carbs as well as cellulose and gluten.

Unique proteolytic enzyme & bioflavonoid formula designed to support the body's immune response.*

Quercetin is a potent bioflavonoid that protects cells and tissues against free radicals.*

Bromelain, papain, and pancreatin provide a mixture of protein-specific and other enzymes that help ensure proper breakdown of protein molecules that may otherwise cause occasional irritation.*

ADVANCED PLANT BASED FORMULA: This formula is power packed with many plant based enzymes that you will not normally find in other products. Our product contains Aspergillopepsin, Amylase, Bromelain, Lipase, Protease, Papain & many other plant based enzymes.

QUALITY YOU CAN TRUST: Our product has been made using high quality ingredients and we strive to keep our prices reasonable.

SUPPORTS DIGESTIVE HEALTH: The ingredients in this product support gastrointestinal and immune health and overall digestion. This product can help in relieving bloating and associated discomfort.

Formulated with a broad range of enzymes

Contains both bromelain (from pineapple) and papain (from papaya)

Easy to swallow soft gels

➕ Packed with Antioxidants - Antioxidants are important for overall health.* Papaya fruit is a great source of vitamins and minerals, including protein, fiber, Vitamin C, lycopene, Vitamin A, potassium and folic acid, making our Papaya Fruit Extract powder, or Papaya Extract, a great addition to any diet for a daily dose of vitamins, minerals and antioxidants!

✔️ For the Skin - Papaya contains lycopene and Vitamin C which are essential for skin health.* Our Papaya Fruit Extract powder, or Papaya extract powder, is a great addition to any diet and healthy regimen for a overall skin health.* Add our papaya powder in your daily routine and keep your skin looking healthy!*

✔️ Pure & Gluten Free - Our Papaya Extract powder, or Papaya powder, does not contain any fillers, additives, and artificial flavors.* Not only that it's filler free, our Papaya Fruit Extract, or Carica Papaya, is also free of gluten, dairy, soy and added sugar which is ideal for those with dietary restrictions.

✔️MAKTREK TECHNOLOGY: 3D Probiotic Delivery System provides better survival of living beneficial probiotics and enzymes; This patented technology provides survivability so healthy probiotics can get into the small intestine to support digestion and comfort.

✔️DIGESTIVE HEALTH SUPPORT: A powerful mixture of Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus plantarum, papain lactase, lipase, and bromelain help the break down of sugars, dairy and fats; The perfect dietary supplement to help support your digestive system.

✔️TRUSTED FORMULA: Our Digestive Enzymes are expertly formulated and manufactured in the USA following strict GMP guidelines; Each batch is third party lab tested to ensure maximum purity and quality.

Stomach Relief: Bromelain, papain, and protease help relieve bowel discomfort, bloating, and gas

Digestive Health: Helps with the breakdown of food sensitivities like gluten, dairy, and beans

More Active: Helps improve food break down to allow full absorption of nutrients for more energy

🌱ADVANCED GI-TRACT HEALTH - Natural Digestive Enzyme formula with probiotics and prebiotics. Fast and efficient digestive enzyme replenishment and easy handling of long-digesting foods. Easy-to-take capsules for facilitated digestion, nutrient absorption, and bloating reduction.

🌱EASY DIGESTION & ABSORPTION — Imagine life without bloating! A two-month supply of fast-acting capsules. Digestive Enzymes capsules are an excellent enzyme mix to easily digest carbohydrates, fats, proteins, fiber, gluten, and dairy lactose products. All the best for your body!

🌱PREBIOTIC & PROBIOTIC DUO — Includes 500 mg of 13 superior enzymes blend, probiotics, prebiotics, and Papaya extract. Support your overall digestive health! Safe and effective capsules for men and women of all ages. Each jar contains 60 capsules with a serving size of 1 capsule daily and will last for two months of proper daily use.