Best Constipation Relief Enzyme Supplements in 2025

DOCTOR FORMULATED IMMUNE SUPPORT FOR KIDS: Supports immune system and digestive health with 5 billion CFU and 14 probiotic strains, prebiotics and Whole Food vitamins C and D, all in one yummy chewable tablet that is gluten free, dairy free and soy free

GLUTEN-FREE DIGESTION SUPPORT: This 5 Billion CFU once daily probiotic supplement contains Lactobacillus acidophilus, gasseri, paracasei, and plantarum as well as Bifidobacterium (Bifidobacteria) lactis, breve, infantis, and bifidum for digestive health

WHOLE FOOD VITAMINS FOR KIDS: One-a-day Tasty Organic Berry Cherry flavor chewable probiotics for kids contain 30mg of Whole Food Vitamin C from Organic Amla Berry plus 400 IU of Whole Food Vitamin D, for added immune support—with no added sugar

Digestive Enzymes with Prebiotics & Probiotics: One before a meal to find relief from occasional bloating, gas, and discomfort from food and alcohol.

Advanced Enzymes Blend: Replenishes digestive enzymes that may decline with age to help break down alcohol, meat, dairy, fried foods, and raw vegetables.

Clinically Proven DE111 Probiotic: Guaranteed to arrive alive and work within hours in small intestine where 90% of nutrient absorption occurs + 70% of immune system resides.

Beat the bloat: Contains powerful and unique blend of bloat-busting digestive enzymes for relief of occasional bloating, gas, and indigestion.

Love what you eat again: Pizza? BBQ? Pasta? 1 capsule before each meal lets you rediscover digestive happiness and helps prevent the uncomfortable, “too-full” feeling after eating.

Restore digestive confidence: Works fast to break down fat, fiber, protein and carbohydrates, all the elements in a typical meal. Food breaks down more quickly, so digestion works more smoothly.

Relieve digestive issues: Enjoy food and feel good afterwards with a broad range of microbe-derived enzymes that help your body break down and digest proteins, fats, carbohydrates, dairy products, sugars and fiber, providing relief from common digestive issues such as gas, bloating, constipation and reflux.*

Beat the bloat: This keto-friendly formula features 10 vegan enzymes, specifically sourced from the USA, Denmark, Japan, Finland and Belgium, for their potency and ability to withstand stomach acid, so they work effectively in the gut and to provide comfort, especially for those experiencing gas and bloating after eating.*

Increase absorption: Our digestive enzyme supplement breaks down food properly, meaning your body can better absorb the essential nutrients it needs, resulting in better gut health and increased energy levels* - you may even be able to start eating many of the foods that used to cause you digestive upset, such as spicy, raw or acidic foods.

⚕️PROPRIETARY COMBINATION OF STRAINS – This probiotic supplement contains 50 Billion CFU making it a highly potent health supplement. Additionally, our CONSTIPATION RELIEF probiotics are formulated with a unique proprietary blend of enzymes and other natural ingredients that aid in digestion while promoting your overall health and well-being.

💚DIGESTIVE ENZYME PROPERTIES – The blend of digestive enzymes in our ultimate flora probiotic helps your body properly digest food. Our vegan probiotics formula contains Milk Thistle and extract from the roots of Dandelion, Ginger, & Turmeric which have been shown to reduce inflammation in the body.

🌿 ESSENTIAL FOR GUT HEALTH – Taking our probiotics for women and men can restore the beneficial bacteria in your gut and work as a detox cleanse for your gut. This is necessary for improving the health of your liver, kidneys, and other organs. The prebiotics and probiotics replenish your intestinal ecology and can improve digestive health.

Superfood Multivitamin: One n Only contains a combination of vitamins, minerals, 7500mg of whole foods, antioxidants, phytonutrients, and Superior Herbs which help support your energy level, hair, skin, and nails.

Natural Energy And Focus: For over 3500 years, Schizandra has been used to improve energy, concentration, memory, and alertness without producing the "jittery" feeling associated with caffeine. In fact, most people find that Schizandra calms as it energizes.

Improved Digestion: Digestive Enzymes help break down proteins, carbohydrates, and fats to assure the quickest, most complete and most efficient digestion possible. Improved digestion helps with bloating, gas relief, constipation, and increased regularity.

STRENGTH IN DIVERSITY - 3 in 1 probiotics for women and men deliver 100 billion CFU per serving from 15 carefully selected active culture strains, premium prebiotics fiber, and broad-spectrum digestive enzymes—far above average—to restore digestive balance and replenish any good bacteria that may have been lost. Combined with antioxidant cranberries and cherries, which are natural extracts, it assists probiotics in all aspects to work for whole-body health.

DAILY DIGESTIVE HEALTH - In order to maximize the utility for digestive health, this formula features our advanced PRO+PRE+Multi-Enzyme system. The prebiotics is there to provide probiotics nutrition and keep them alive on the way to the gut, to help rebuild the intestinal and bacteria environment. Enzymes help you digest fried, spicy, raw, processed food, dairy, salts, carb/carbohydrates. Built into this advanced formula, there’s no need to buy probiotics and digestive enzymes separately.

HIGHER PROBIOTIC SURVIVAL RATE - Different parts of your body need different probiotics. Our probiotics with digestive enzymes are protected by a patented 3-layer acid-resistant technology that results in healthy bacteria releasing in the right part of your body to have the most effect. ZEBORA probiotic ensures that 83% of the probiotic bacteria reach the intestine alive, compared to an average of 7% across 10 leading US probiotic brands.

PROBIOTIC MULTI-ENZYME COMPLEX: Formulated with crucial probiotic strains and multiple food enzymes, MAV Nutrition’s Digestive Enzymes complex is designed to support digestion, ease gas and bloating, and increase nutrient absorption.*

BLOATING & GAS RELIEF: Beat the bloat! This powerful blend of essential enzymes like Lactase, Bromelain, Papain, Protease, and more provides digestive support and relief for gas and bloat after eating.

WITH 3 STRAINS OF LACTOBACILLUS: Our Digestive Enzymes are formulated with 3 potent strains of Lactobacillus probiotics to support optimal digestion and a healthy gut biome.*

Powerful supplements with a digestive enzyme: Digestive Enzymes 1000MG blend are powerful supplements with a natural enzyme, prebiotic, and probiotic blend to promote healthy digestion for men and women.

Benefits: This Transformation Enzymes Breaks down hard to digest foods, Support gas, bloating, and discomfort, enhances nutrient absorption, Healthy immune system, promotes constipation relief, manages sugar level, and promotes healthy metabolism.

Promotes fast digestion: The probiotic Digestive Enzymes supplements help to convert food to energy efficiently. The formula of the supplements features an advanced multi-enzyme system to help you to digest hard food. It supports the digestive system's function well and optimizes nutrient availability.

Guard your lawn & help your pet - Zesty Paws Stay Green Bites are lawn protector chewables that get to the source of grass burn caused by dog urine to help your lawn go from burned to beautiful, while also providing digestive and bowel support.

Enhanced with Cran-Max - This formula contains 50mg of Cran-Max, a concentrate made from cranberries using patented Bio-Shield technology, clinically proven to flush out bad bacteria to support the bladder, urinary tract, UT & digestive health.

Grass & Garden saver formula - Each soft chew contains 250mg of DL-Methionine, which is an essential amino acid that contains special properties that may help to reduce the nitrogen levels in your dog’s pee to put an end to lawn burn.

🛡️ BLOCKS INTERFERING DIETARY LECTINS: Add lectin supplements in your daily diet – and notice the difference. Lectin Defense shields your body from harmful Lectins. Found in fruits, vegetables, seafood, and in particular grains, LECTINS CAN SLOWLY CAUSE LONG TERM HEALTH PROBLEMS, BY CREATING INFLAMMATION. GoBiotix lectin shield supplement formula is an effective way to help aid your body’s overall health, fight against lectins, and safely remove them while reducing gas and bloating.

✅ SUPPORTS INTESTINAL & DIGESTIVE HEALTH: This groundbreaking new formula was created to OFFSET THE DISCOMFORTING EFFECTS OF LECTINS (proteins commonly found in plants that make them harder to digest). Lectin foods pervade the typical American diet and it can be difficult to maintain a completely lectin-free diet. This is where Lectin Defense comes in. Our lectin blocker protects you from a pile-up of lectins & to promote full-body comfort, enzymes for digestion, and promoting intestinal health.

📉 HELPS REDUCE GAS & BLOATING: We all know the frustration and psycho-physical pain gas and bloating can cause. Here is where our Lectin defense can be of great help. Specially formulated with key nutrients, Lectin Defense attracts troublesome lectins from the foods you eat and help to safely rid them out of your body. Don’t miss this lectin guard bloating supplement that can SIGNIFICANTLY REDUCE, OR EVEN END, THE GAS, BLOATING AND INDIGESTION you’ve been suffering with for so long.

We Stand Behind our Products - Feel better or your money back!

Stop Bloating, Stomach Discomfort & Gas: Yuve Daily Cleanse can help digesting fats, fiber, cellulose, protein, gluten by supporting the breakdown of difficult to digest foods and ease the pain or discomfort caused by irritable bowel syndrome, diarrhea, gas, bloating, constipation, and other gastrointestinal issues.

More Efficient Use Of Your Energy: These Digestive Enzymes help your digestive system work more efficiently and consume less energy while processing food. No more after meal fatigue! Get an energy boost for the things you love!

Bloated Belly Relief - Flatter Me is a blend of full-spectrum enzymes for digestion and bloating relief for women.*

What's Inside - Flatter Me's unique no bloat formula contains 18 full-spectrum digestive enzymes plus ginger, peppermint leaf, and fennel seed, avoiding the need for individual products like peppermint capsules for bloating and more.*

Digestion Support - This anti bloat formula includes ginger and peppermint leaf to support digestive health. Fennel seed helps soothe digestion and support nutrient absorption. A potent digestive enzyme blend helps break down food for gas and bloating relief.*

Beat the Bloat & Say Goodbye to Meal Time Discomfort: 16 beneficial enzymes that digest proteins, carbs, fruits, veggies, beans, dairy, & fats to cover all diets. With SBO Probiotics & Prebiotics to aid digestion further - Your New Meal Time Hack!

Dual Action Relief: Our powerful digestive enzymes aid with breaking down food while the prebiotics & probiotics promote digestive function in the gut. They work synergistically to provide relief from mealtime discomfort.

Probiotics that Survive the Gut: Formulated with 3 soil-based probiotic strains - specifically selected due to their ability to survive the harsh gut environment. Along with Organic Prebiotics that fuel the growth of healthy bacteria in the gut.

Contains LACTASE DIGESTIVE AID, the digestive enzyme that breaks down lactose, the cause of lactose intolerance.

Bloating and gas relief : 18 Digestive Enzyme Supplement breaks down PROTEIN, FATS, CELLULOSE, CARBS, and FIBER for more complete digestion and less constipation.

Contains 60 Vegetarian and gluten free leaky gut repair ultra bowel support supplement pills

❤️ ️ #1 RECOMMENDED ENZYME SUPPLEMENT FOR MEN & WOMEN - Enzyme +7 helps aid with acid reflux and also reduces gas and bloating.

❤️ ️BEST DIGESTIVE ENZYME - HELPS TO PROCESS DIFFICULT TO DIGEST FOODS - NO MORE ACID REFLUX,AND IMPROVE INDIGESTION: All you need to do is take 1 tablet 10 minutes before each meal.

❤️ ️ IMPROVE HOW YOU DIGEST NUTRIENTS NOW - This enzymatic formula is the ultimate aid that boosts the body's ability to digest fats, fiber, protein and carbs as well as cellulose and gluten.

EAT CHEESE, ICE CREAM, AND YOGURT AGAIN - Our pills allow you to enjoy your favorite milk based foods without discomfort! Each chewable tablet provides 3000 FCC of highly active lactase enzyme

NATURAL DIGESTIVE AID - Our tablets provide relief from bloating, constipation, gas, diarrhea, stomach ache and other symptoms associated with inadequate lactose or dairy consumption

WORKS QUICKLY - Our dairy pills can be taken immediately before or after a meal to aid digestion

✔️MAKTREK TECHNOLOGY: 3D Probiotic Delivery System provides better survival of living beneficial probiotics and enzymes; This patented technology provides survivability so healthy probiotics can get into the small intestine to support digestion and comfort.

✔️DIGESTIVE HEALTH SUPPORT: A powerful mixture of Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus plantarum, papain lactase, lipase, and bromelain help the break down of sugars, dairy and fats; The perfect dietary supplement to help support your digestive system.

✔️TRUSTED FORMULA: Our Digestive Enzymes are expertly formulated and manufactured in the USA following strict GMP guidelines; Each batch is third party lab tested to ensure maximum purity and quality.

✅ Proudly Made in USA 🇺🇸 - Sunnychews Probiotics for Dogs is an advanced soft chew supplement with probiotics, dog probiotics and digestive enzymes to support digestive health, immune system, allergy relief and dog upset stomach relief. It make helps dogs gas

✅ Probiotic for dogs support dog gut health and prevent against occasional dog diarrhea, dog gas relief, and constipation. Our pet probiotics for dogs supplement is all-natural supplement for health issues such as upset stomach, bloating.

✅ Tasty probiotic dog chews. With no artificial flavors, delicious natural taste treats for dogs. Also known as dog probiotics and digestive enzymes, probiotics with enzymes for dogs, dogs probiotics, dog probiotics chewable, probiotics dogs, probiotics for puppies, and pet probiotics. We care about your pet’s wellness & happiness, so make only great products for your pups.

⭐ FINALLY, FEEL COMFORTABLE! Have you ever had stomach issues that turned your day upside down? We’ve got some good news...you don’t have to feel that way! Beat those digestive problems with just one bottle - our Digestive Enzymes supplement. It’s formulated to ease discomfort in your system so you can enjoy life comfortably. It’s packed with everything your gut needs - digestive enzymes. Feel the transformation from the inside out!

⭐ PUT AN END TO YOUR TUMMY ISSUES: Do you have frequent and irregular bowel movements? Are you looking for something that truly works to ease bloating, constipation, or IBS? Can’t wait to enjoy a delicious meal without worrying about indigestion? Packed with the most essential enzymes to help digest protein, carbs, fat, and sugar, our supplement promotes better digestion, enhanced nutrient absorption, and happier days. Finally, you and your tummy can feel good again!

⭐ POWERFUL ENZYMES IN EVERY SERVING: Lots of people struggle with food intolerance and discomfort. If you’re one of them, you know how frustrating it can be always having to watch what you eat, and worrying about the aftermath! Digestive enzymes are an important part of managing these issues.

Stomach Relief: Bromelain, papain, and protease help relieve bowel discomfort, bloating, and gas

Digestive Health: Helps with the breakdown of food sensitivities like gluten, dairy, and beans

More Active: Helps improve food break down to allow full absorption of nutrients for more energy

VIABILITY : We use only those probiotic strains that have survived the intense fermentation process needed to make Kimchi - and by extension, the harshest conditions of the gastrointestinal tract. In fact, 90% of these probiotics reach the intestine in a living state - compared to only 20-30% of animal lactic acid bacteria found in other probiotic foods.

PATENTED STRAIN : Lactobacillus Sakei proBio65 is patented* and clinically shown to "Reduce atopic dermatitis(eczema) and allergy-related disorders" by improving immune function. *US 8,034,606 B2 (Patent No.)

DAILY DIGESTIVE & IMMUNE SUPPORT: Lactobacillus Brevis proBio-96 and Weissella Koreensis proBio-97 replenish friendly bacteria to restore gut health to its optimal state. Enjoy improved digestive and immune function, and find relief from uncomfortable bloating, gas, and constipation.

DIGESTIVE & GUT HEALTH: Enzymates Doggy Digestive Enzymes + Pumpkin offers a unique blend of enzymes, custom probiotics, brewer’s yeast and pumpkin for digestive and gastrointestinal health; our enzyme blend specifically formulated for dogs can provide relief from diarrhea, constipation, gas, bloating, and irritable bowels. and more as they help maintain healthy, balanced intestinal microflora, making vitamins and nutrients, and supporting the immune system

UNIQUE ENZYME FORMULA: Including Therablend, Formulated by the Enzyme experts at Enzymedica, this digestive supplement for dogs includes protease, to hydrolyze protein; Amylase, Glucoamylase, and Alpha-galactosidase to hydrolyze carbohydrates; Lipase, to hydrolyze fats; Cellulase, Pectinase, and Phytase to break down cellulose such as corn and wheat common in many popular pet foods.

SUPERFOOD BLEND: Special formula combines high fiber pumpkin and brewer’s yeast to soothe your pet’s upset stomach, helps maintain healthy, balanced intestinal microflora, supports nutrient absorption and the immune system.

OPTIMIZES DIGESTION - Our enzymes for digestive health contain a comprehensive combination of different strains of powerful enzymes, designed to optimize digestive function. They assist in the breakdown, digestion, and absorption of proteins, carbohydrates and fats in food.

UPSET STOMACH RELIEF - Many people experience difficulty digesting food due to poor enzymes or hydrochloric acid levels, which stops them from breaking down their food effectively. Our super digestive enzyme has a special PH sensitive coating which allows capsules to pass through the acid medium of the stomach and into the digestive tract.

HELPS REDUCE GAS & BLOATING - Our enzymes for digestion not only support optimal nutrient absorption, but can also help to reduce and prevent digestive upset such as bloating and reflux as well as nausea and gas and also provide bloating relief and constipation relief for adults.

TRUE HEALTH STARTS IN YOUR GUT: Loosen Up soluble fiber supplement increases motility, helps relieve constipation, and alleviates irritable bowel syndrome (IBS) symptoms. Like all of our formulas, Loosen Up is clinician-developed, optimizes digestion, enhances detoxification, helps regulate hormones, and boosts your microbiome.

WHO IT'S FOR: Loosen Up is for people who experience strain, pain, and/or inconsistent bowel movements, and for people who have adverse reactions to psyllium. Most ideal for individuals who experience pain with constipation, irritable bowel syndrome (IBS), and a counter reaction to psyllium husk. Also for those looking for help with hunger control.

WHAT TO EXPECT: You should see gradual improvements in regularity and stool consistency over a period of 1 to 4 weeks. After 2 to 3 months of daily use, patients report a range of improvements including better sleep, balanced hormones, more energy, clearer skin, and better metabolism.

Digestive Supplements - Our digestion supplement for women and men offers extra Bloating relief and Digestive support for a complete digestive aid supplement you can trust for your well-being

Digestive Enzyme Complex - Upgrade your digestion pills with our digestive enzyme supplement made with super digestive enzymes for one of the best gut health supplements for women and men

Gut Cleanse - Give your body a digestive cleanse and detox so you can feel better whether you’re looking for a bloated stomach cleanser for men and women or debloat pills for everyday use

✅ 100% RISK-FREE MONEY-BACK GUARANTEE - Support better digestion and a robust microbiome with Lumen Digestive Enzymes, or get 100% of your money back. That's our guarantee to you. Whether you've taken just one pill or used the entire bottle. Ideal for women and men who want a RISK-FREE way to improve their digestive health.

💪 FIGHTS COMMON DIGESTION ISSUES - This specially formulated enzyme and probiotics supplement may provide support against common digestive problems. These essential enzymes help combat gas, bloating, and may offer constipation relief by helping to further break down foods.

❤️ IMPROVES GUT HEALTH - With its proprietary Makzyme-Pro enzyme blend and other important enzymes for digestion, Lumen Digestive Enzymes assists with digestion of protein, carbs, fats, and lactose with proteolytic enzymes and other enzymes such as lipase and lactase, allowing you to get the most nutrition out of your meals.

Upgraded Gut Support Formula: With a new look and a new name, a good thing just got better. Based on the latest scientific research, we enhanced our broad-spectrum digestive enzyme formula and added 3 adaptogenic superfoods to further support digestion.

Physician Formulated: UpWellness products are formulated by our wonderful naturopathic physicians Dr. Josh Levitt, a specialist in natural medicine, and Dr. Amanda Levitt, an expert in nutrition and herbal medicine. Wellness starts in the gut and Total Revive + is designed to aid overall gastrointestinal function and support regularity. Get relief from bloating, gas, constipation, and more as you begin to thrive from the inside out!

Plus 3 New Key Enzymes and Herbal Adaptogens: Total Revive + now has a wider range of benefits. Our expert formula now has Lipase, Cellulase, and Serratiopeptidase to support proper breakdown of a wider range of foods. We made it even better by adding potent adaptogen superfoods Amla, Gotu Kola, and Holy Basil to help increase energy and vitality and support skin health.

ESSENTIAL ENZYMES FOR DIGESTIVE SUPPORT - Good health begins in the gut! This wellness formula with daily essential enzymes supports healthy digestion and may provide upset stomach relief, gerd relief, constipation, gas and bloating relief, or prevent various types of digestive discomfort

CONVERTS FOOD TO ENERGY - The combination of 18 enzymes and nutritious extracts in our digestion supplement that decrease as we age. It promotes optimal digestive health, gut immunity, and cholesterol balance

BREAKS DOWN HARD TO DIGEST FOODS - The advanced Multi Enzyme System with Protease, Bromelain, Papain, Lipase, Galactosidase may help you digest fried, spicy, raw, and processed foods. Lactase enzyme can provide more efficient lactose digestion and less bloating after eating dairy, Aspergillopepsin enhances gluten digestion*

Get ready to experience the ultimate digestive support Pick me up blend with KORESELECT Enzyme Blend with Apple Cider Vinegar! Our specially selected blend of 17 enzymes will not only improve your digestive health but also enhance your nutrient uptake, making you feel more energized and revitalized.Our powerful digestive enzymes are specially designed to break down carbohydrates, proteins, and fats, ensuring that your body absorbs all the essential nutrients it needs to thrive.

Gut wellness and MORE*:this formula is a great choice for women & men looking for natural ways to promote digestive efficiency and reduce bloating. Packed with powerful ingredients like Papaya, Ginger, and Apple Cider Vinegar to help improve overall digestion and relieve gas and bloating problems. With the added benefits of amylase and lipase enzymes, our blend helps break down carbohydrates and fats for optimal gut health.

Digesting boost & immunity care :Packed with energizing apple cider vinegar and digestion-boosting ginger and papaya, this supplement is an essential way to boost your energy levels, support your immune system, and even enjoy clearer skin. Ginger and papaya are added to help break down food during digestion. Papaya is known for its ability to break down proteins, while ginger helps your intestines absorb more of the important nutrients.