Best Prebiotic Enzyme Supplements in 2026

Certified USDA Organic, Non-GMO Project Verified, Gluten Free, Dairy Free, Soy Free, Vegetarian

Immune System & Digestive Support

Vitamin C from Organic Amla (30mg), Vitamin D (400 IU) and prebiotic fiber all help maintain a healthy immune system.No Refrigeration Required

Made for Healthy Digestion & Gut Immune Function: Formulated with 4.4 billion CFU spore-forming probiotics with built-in prebiotics, this dietary supplement helps support digestion, gut health and gut immune function*

Designed for Easy Digestion & Absorption: Contains an active blend of probiotics, including DE111, a clinically tested spore-forming strain that withstands stomach acid and is released in the intestine for better absorption.

Advanced, Dual Benefit Formula: Built-in PreforPro Prebiotics boost the effectiveness of probiotics, even in small doses. Together prebiotics and probiotics support the normal proliferation of beneficial gut flora and help to ease the digestive process.

Prebiotic Probiotic Combo : Our Pre-Pro is designed to support digestive health & gut health. A great choice for those looking to support a diverse healthy microbiome - contains 250mg of Prebiotic Chicory Root Inulin.

Prebiotic Focused: Our Prebiotic-Probiotic is crafted to create a synergistic combo that helps support your gut health. Contains 10B CFU of 3 diverse Lactobacillus probiotic strains.Expertly crafted to support occasional constipation, diarrhea, gas & bloating!

Survives the Gut: From start to finish - this probiotic is designed to survive the gut & maximize the colonization of our strains. We use a shelf-stable bottle, acid-resistant capsules, and 10 Billion Colony forming units (CFU) to achieve this!

60 BILLION CFUs - This probiotic supplement features 10 unique strains of probiotics and contains a proprietary blend of 4 incredible prebiotics you won't find anywhere else. Each capsule features a delayed-release. Recommended usage is only 1 capsule per day. Includes a 30 day supply.

𝗨𝗦𝗔 𝗚𝗠𝗣 𝗖𝗘𝗥𝗧𝗜𝗙𝗜𝗘𝗗 𝗠𝗔𝗡𝗨𝗙𝗔𝗖𝗧𝗨𝗥𝗜𝗡𝗚 - Our state-of-the-art manufacturing facilities are located in the US and are staffed with highly trained individuals who formulate superior products. Being certified under US laws and regulations (GMP Certified), these facilities are uncompromising when it comes to cleanliness and quality control.

𝗜𝗡𝗖𝗥𝗘𝗗𝗜𝗕𝗟𝗘 𝗜𝗡𝗚𝗥𝗘𝗗𝗜𝗘𝗡𝗧𝗦 - We're sorry to say it, but if you’re looking for cheap, you’re in the wrong place. We search far and wide, domestic and international, to provide high-quality ingredients for which your body will thank you. Unfortunately, getting the best ingredients from domestic and international farms can come at a higher-than-normal cost. If quality, satisfaction, and results are essential to you, you’re in the right place!

High Strength & Hypoallergenic - Premium support blend of 12 safe, complementary and well-studied species to support optimal gut flora, immune & GI health. Hypoallergenic 25 billion CFU in a base of chicory-derived prebiotic inulin.*

Probiotic Survival Without Extra Additives - Ther-Biotic does not need additive-packed spheres or tablets to promote probiotic survival. Advanced InTactic technology helps live probiotics reach the small intestine and colon. Each bottle is formulated with sufficient overages, handled with care, and tested for potency that delivers on its promise.*

Protection From Stomach Acid - On exposure to stomach acid, an InTactic 'shield' forms a gel-like matrix surrounding the probiotics, protecting them from damage. On passage into the duodenum, InTactic is designed to break down and release live microorganisms for optimal efficacy.*

CONVENIENT DAILY FIBER GUMMY: Increase your daily fiber intake with Phillips’ fiber supplement gummies containing soluble inulin fiber

PLANT-BASED PREBIOTIC FIBER: Works with your body to help feed good bacteria in your gut

4G OF FIBER PER SERVING: Take two gummies per serving to help supplement your daily fiber intake

BroccoMax- BroccoMax is a standardized concentration of sulforaphane glucosinolate (SGS) & the enzyme myrosinase from broccoli seeds that are processed using ultra-clean technology. It is bioavailable, well absorbed and supports phase 1 detoxification.

Cell Replication & Liver Health - BroccoMax broccoli seed extract is manufactured to preserve myrosinase, which is the enzyme in broccoli that metabolizes SGS into sulforaphane. Sulforaphane supports healthy cell replication and division.

Veggie Capsules - Take 2 capsules per day, 30 minutes before or after a meal, or as directed by your qualified healthcare professional. Suitable for vegans and vegetarians.

DOG PROBIOTIC HEALTH SUPPLEMENTS: Feel good about feeding your dog or cat these pet health supplements that feature a blend of enzymes, prebiotics and vet strength PB6 probiotics designed for sensitive stomachs, pet diet changes and digestive issues.

CAT, DOG DIGESTIVE SUPPORT: This premium pet health supplement fuels your dog or cat with probiotics and prebiotics to help with changes in diet, consistent stool quality and stomach and intestinal balance. Each powder probiotic and cat prebiotic supplement features flavoring that tastes great.

IDEAL PET SUPPLEMENT FOR CAT DIGESTIVE PROBLEMS: It’s natural for animals to feel stress when boarding or during grooming. This stress can impact and cause digestive problems in dogs and cats. This dog supplement and cat supplement helps to counteract the stress and work to restore gastrointestinal health for dogs and cats.

Each easy to swallow capsule contains 10 Billion CFU's of Bacillus Coagulans. The usage of specific probiotics after weight loss surgery may help reduce gastrointestinal issues (bloating, gas, and bowel irregularities), increase the absorption of vitamin B12, Increase metabolic balance to promote further weight loss after bariatric surgery, and enhance immune response.

Bariatric Fusion Probiotics contain Bacillus Coagulans, which has been shown specifically target the intestinal tract. Probiotic benefits may be effective to help create a microevironment inside your digestive system that encourages nutritional absorption and increase energy levels. s a probiotic strain resistant to heat and gastric acid. It may improve the immune system and treat diarrhea and constipation. Bacillus Coagulans forms reproductive structures called spores.

Very easy on your stomach and easy to digest. No GI side effects! May promote a healthy intestinal environment, improves energy levels and immunity!

⚕️PROPRIETARY COMBINATION OF STRAINS – This probiotic supplement contains 50 Billion CFU making it a highly potent health supplement. Additionally, our CONSTIPATION RELIEF probiotics are formulated with a unique proprietary blend of enzymes and other natural ingredients that aid in digestion while promoting your overall health and well-being.

💚DIGESTIVE ENZYME PROPERTIES – The blend of digestive enzymes in our ultimate flora probiotic helps your body properly digest food. Our vegan probiotics formula contains Milk Thistle and extract from the roots of Dandelion, Ginger, & Turmeric which have been shown to reduce inflammation in the body.

🌿 ESSENTIAL FOR GUT HEALTH – Taking our probiotics for women and men can restore the beneficial bacteria in your gut and work as a detox cleanse for your gut. This is necessary for improving the health of your liver, kidneys, and other organs. The prebiotics and probiotics replenish your intestinal ecology and can improve digestive health.

PROBIOTIC SUPPLEMENT: GI Natural's clinically designed formulation contains a unique blend of prebiotics, probiotics, enzymes, and supportive nutrients for a healthy gastrointestinal mucosal tract.

BEYOND DIGESTIVE AID: Our formula strengthens the GI tract’s vital mucosal lining. It may counter occasional heartburn, reflux, gas, bloating, diarrhea, and other digestive discomforts.

PURITY: GI Natural is hypoallergenic, gluten-free, vegetarian, and free from artificial colors and preservatives - helping to unlock the energy and health-boosting nutrition of foods.

3-IN-1 FORMULA: With a guaranteed 65 billion CFUs per capsule (that’s a lot of good bacteria), and enhanced with Cranberry fruit and 60mg of fiber inulin, this once daily delayed-release probiotic in a veggie capsule provides valuable gut and digestive tract support*

ENHANCED FORMULA: Our proprietary formula combines 16 strains of Lacto and Bifidobacteria shelf-stable probiotics, bringing you digestive enzyme and fatty acid production support, longer*

LONGER SHELF LIFE: Unlike other probiotics, our probiotic blend is guaranteed fresh through the expiration date, meaning you can reap the benefits of 65 billion CFUs for gut health and support

ALL-NATURAL PROBIOTIC & PREBIOTIC FORMULA - Our Ingredients Are All Sourced from Natural Ingredients, 100% Pure, NON-GMO, Gluten and Allergen Free.

HELP YOUR DIGESTIVE SYSTEM - Our Probiotic Formula Contains Live Microorganisms that Helps Keep a Healthy Digestive Tract.

ENHANCED WITH PREBIOTIC FIBER - This Special Form of Dietary Fiber Acts as a Fertilizer for the Good Bacteria in Your Gut

PREBIOTICS AND PROBIOTICS SUPPLEMENT: Formulated with a prebiotic and 7 live probiotic strains, this supplement can help to replenish the natural balance of gut flora within the digestive system and help support immune system balance.

ACID- & BILE-RESISTANT PROBIOTIC CAPSULES: Our durable probiotic supplement contains 7 different probiotic strains of human origin, so it's easier to adapt to the human body. This men’s and women’s probiotic is also resistant to stomach acid and bile.

MADE WITH CARE: These capsules are mindfully sourced and contain the following natural probiotic strains: L. acidophilusL. casei (10%); L. plantarum (10%); L. rhamnosus (10%); B. lactis (10%); B. longum (5%); and S. thermophilus (5%).

GUT AND DIGESTIVE HEALTH: Our propriety fiber blend feeds and promotes growth of good bacteria for sustained, natural support and protection through stomach acid environment

TESTED: 15+ billion CFUs and 15 clinically tested, documented probiotic strains with proven results in the small and large intestine to help with function in the digestive, metabolic, and immune system

DELIVERY: Patented, foil-sealed packaging protects culture viability through range of temperatures, ensuring they are live and active when consumed for enhanced absorption

PREMIUM INGREDIENTS MADE IN USA – NWC Naturals products are made in the USA in a GMP Certified Factory. Under strict quality and safety standards, our products are formulated just for pets with human quality ingredients. All the probiotics used are approved by AFFCO as being safe for dogs, cats, and horses. Our wonderful Total-Biotics powder contains 14 of the most researched productive live and stabilized probiotics available.

SAFE FOR PETS OF ALL AGES: Start giving Total-Biotics when your pets are young, it will give them the vital support they need to grow and develop to their optimum level of health. No matter the breed or age, using Total-Biotics daily helps support regularity, good digestion, a strong immune system, and a healthy digestive tract. A healthy pet is a happy pet.

EXCLUSIVE DELIVERY OF NUTRIENTS: Total-Biotics by NWC Naturals is the only probiotic formula that uses the only patented stabilized glutamine in the world, MGG Chelate. With the Live Enzyme Activated Delivery System (L.E.A.D.S.), we ensure the best delivery and colonization of these probiotics. The L.E.A.D.S. system works to deliver the probiotics and activate the prebiotics to deliver the nutrients in this form.

Probiotics + Prebiotic + Digestive Enzymes: 3-in-1 digestive health solution with clinicallyproven DE111 probiotic plus a spore-forming probiotic blend, a prebiotic, and a multi enzyme blend.

Clinically Proven DE111 Probiotic: Guaranteed to arrive alive and work within hours in small intestine where it inhibits candida growth and promotes overall women’s health.

Probiotics Alone Aren’t Enough: Probiotics PLUS digestive enzymes provide overall microbiome and digestive health and helps break down foods to reduce gas and discomfort.

Advanced 2-In-1 Digestive Support: Combines Digest Gold with 1.5 billion active probiotic cultures to help relieve occasional bloating, gas, and irregularity, while supporting a healthy microbiome.

Speeds Up Digestion: For when you feel bloated and heavy (no matter what you eat), this enzyme blend helps break down food more quickly while promoting a healthy microflora so digestion works smoothly.

Most Advanced Support: One capsule with every meal provides powerful enzymes to digest proteins, carbohydrates, dairy, fats, and fibers – even for your largest meals.

Powerful supplements with a digestive enzyme: Digestive Enzymes 1000MG blend are powerful supplements with a natural enzyme, prebiotic, and probiotic blend to promote healthy digestion for men and women.

Benefits: This Transformation Enzymes Breaks down hard to digest foods, Support gas, bloating, and discomfort, enhances nutrient absorption, Healthy immune system, promotes constipation relief, manages sugar level, and promotes healthy metabolism.

Promotes fast digestion: The probiotic Digestive Enzymes supplements help to convert food to energy efficiently. The formula of the supplements features an advanced multi-enzyme system to help you to digest hard food. It supports the digestive system's function well and optimizes nutrient availability.

Probiotics Dogs Love - Give your dog digestive support with our canine probiotic chews. Help with large dog diarrhea, dog gas, belly discomfort, or loose stools. Pet Probiotic digestive enzymes for dogs support healthy bacteria in your dog's stomach.

Not all Dog Probiotics are made equal - Our dog Probiotic Chews include Prebiotics for dogs. As a member of the NASC (National Animal Supplement Council) PawMedica takes every step needed to ensure we're delivering a high quality probiotic for pets.

Support Healthy Dog Digestion - A Pet Probiotic for dogs helps support dog digestive enzymes and assists healthy dog vitamin absorption. Enzyme chews for dogs & digestive enzymes for pets help your dog's GI tract work smoothly and gives your dog gas relief.

ONLY NATURAL PET PROBIOTICS BLEND DOG & CAT SUPPLEMENT - Contributes to the health and balance of your pet's intestinal tract

2.5 BILLION MICROORGANISMS PER GRAM - This formula is a multi-strain combination of bio-available microorganisms in a prebiotic base of fructooligosaccharide (FOS). Manufactured to ensure maximum potency and stability at room temperature.

HEALTHY DIGESTION - Probiotics are used to help occasional diarrhea, flatulence and foul smelling stools, and are absolutely essential for any animal receiving antibiotics or any other prescription drugs that deplete intestinal microflora.

Probiotic + Prebiotic + Digestive Enzyme + Cranberry: Bonawell Probiotics for Women combines broad-spectrum live probiotic strains, several types of soluble prebiotic fiber, an array of different digestive enzymes, and organic cranberries. This groundbreaking mixture helps boost digestive function, fortify the immune system and enhance feminine health.*

Vaginal & Urinary Support*: Intended for a woman’s unique needs, our Women’s Probiotics has selected specific strains to bolster vaginal and urinary health, including Lactobacillus rhamnosus and Lactobacillus reuteri.* Each capsule also comes with organic cranberries that have been proven to promote urinary tract health.*

A Large CFU Count and Diverse Strains: Our 4-in-1 Probiotics for Women carries an impressive 100 billion CFU from 35 active strains to increase the microbial richness and diversity in your body.* Each bottle offers a guaranteed shelf life without refrigeration and utilizes delayed-release capsules to ensure these microbes’ survival and delivery to the desired location.

Make your morning complete; scientifically backed & clinically proven, formulated with 20 billion cfu featuring targeted release technology to help probiotics survive stomach acid

Prebiotic & probiotic supplement; the probiotics are extremely important for gut health; but, what about their fuel and energy; that is where prebiotics, or the probiotics food, comes in; to help activate you and your optimal health

Bloating relief support and digestive health; our probiotics for men and women help to decrease bloating and increase healthy environment for your gastrointestinal tract; with a healthy system, the acidophilus probiotic aids bad breath treatment; bloating relief support and weight loss support; two in one

5 Billion CFU: Get your digestion on the right track; Our gummies have 5 Billion CFU to give you powerful digestive support

Lactobacillus Paracasei: L Casei is commonly known to support regularity during digestion

Lactobacillus Salivarius: Salivarius helps support your colon and help your intestines

28 STRAINS OF SOIL PROBIOTIC: Helping ameliorate allergies, bloating, gas, constipation,diarrhea, digestive health.Replenishes healthy GI microflora Promotes a healthy gastrointestinal environment ,Relieves occasional abdominal discomfort and Alleviates occasional indigestion and nausea Promotes a normal bowel pattern

Support your mood and boost immune, energy as well as help lose weight and create a balance of the microenvironment inside your digestive system that encourages nutrient absorption and makes the enzyme that helps you feel more happy, energetic, and vibrant.

Viability, the seed-like structure encasing the probiotic bacteria in Prescript-Assist also protects them against degradation by stomach acid, so they reach their target destination, they become active and multiply.

Bloated Belly Relief - Flatter Me is a blend of full-spectrum enzymes for digestion and bloating relief for women.*

What's Inside - Flatter Me's unique no bloat formula contains 18 full-spectrum digestive enzymes plus ginger, peppermint leaf, and fennel seed, avoiding the need for individual products like peppermint capsules for bloating and more.*

Digestion Support - This anti bloat formula includes ginger and peppermint leaf to support digestive health. Fennel seed helps soothe digestion and support nutrient absorption. A potent digestive enzyme blend helps break down food for gas and bloating relief.*

ADVANCED ENZYME FORMULA: No more fearing food intolerance and avoiding certain foods, this complete multi enzyme complex digest proteins, carbs, fats, sugars, wheat, dairy, grains, gluten, lactose and more, for a better digestion

BROAD SPECTRUM BLEND: A digestive relief formula that breaks down unwanted wastes such as toxins, cellular debris and undigested proteins. Helps relieve inflammatory bowel discomfort, IBS, bloating and gas with the combination of ingredients such as protease, bromelain and papain

NATURAL PREBIOTIC & PROBIOTIC BALANCE: Offering beneficial gut flora for a healthy digestion & immune system; 18 critical enzymes: amylase, lipase, lactase & many more, supporting natural intestinal flora and nutrient absorption

16-STRAIN PROBIOTIC - Purity Lab’s high potency Probiotic supplement utilizes 16 important probiotic strains to help promote a strong immune system. Equivalent to 90 Billion CFU, this supplement delivers highly concentrated levels of probiotics.

DIGESTIVE SUPPORT - Our formula includes a Prebiotic in each pearl to help feed the probiotic for increased potency. These prebiotic fibers can help support a healthy gut microbiome and gastrointestinal health. Also supports skin, hair, eyes, and nails.

SPECIALLY FORMULATED - Our Probiotic supplement is a patented micro-pearl delivery system for maximum absorption.  Our manufacturing process guarantees a shelf life of 18 months from the date of being manufactured.

For a Perfectly Balanced Gut: Boost energy and digestive function with our probiotic and prebiotic for women and men. This digestion aid assists metabolism and keeps a happy gut flora with 750 Million CFU, vegan superfoods, and fiber.

Organic Blend with No Added Crap: Our probiotics and prebiotic powder features 3 premium plant-based strains — bifidobacterium longum, lactobacillus gasseri, and bifidobacterium bifidum, and natural fruits to make you feel better every day.

Bursting with Flavor: This anti-bloating powder serves as an immune system booster with tasty vitamins and antioxidant-rich ingredients such as Organic Tapioca, Apple, Raspberry, and Stevia that add sweetness minus the carbs and calories for optimal weight management.

10 RESEARCHED-BACKED STRAINS WITH 20 BILLION ACTIVE CULTURES: Wild probiotics and prebiotics is formulated with TEN research-backed strains of gut probiotic strains with 20 billion active cultures to help repopulate healthy gut bacteria. It promotes healthy digestion, immunity, and reduced cramping/bloating with a daily dose.

ESSENTIAL DIGESTIVE ENZYMES FOR YOU: With its unique blend of prebiotics, probiotics, and digestive enzymes, it provides comprehensive gut health support. By taking Wild Foods probiotic with digestive enzyme daily, you can improve your gut health and promote healthier skin and hair.

SUPPORTS IMMUNE SYSTEM: Studies show that 70% of our immune system lives in our gut. By taking digestive enzymes with probiotics and prebiotics daily, can keep your immune system in tip-top shape. Blend of this digestion supplement supports a healthy gut, which in turn help a healthy immune system.