Best Cream Hemorrhoid Gels in 2025
Daisy
Last Updated: Nov 3, 2025
Daisy
Last Updated: Nov 3, 2025
* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Four 48 count packs of Preparation H Hemorrhoid Wipes with Witch Hazel for gentle, everyday cleansing
Hemorrhoid treatment delivers relief of irritation caused by external hemorrhoids while cleansing the affected area
Medicated wipes formulated with soothing aloe and cleansing witch hazel
Flushable wipes help temporarily relieve skin irritation associated with hemorrhoids
Preparation H medicated wipes are biodegradable and septic safe
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Includes one 2.0 ounce tube of Preparation H hemorrhoidal ointment for hemorrhoid symptom relief
Provides prompt, soothing relief for hemorrhoid itching, burning and discomfort
Relieves both internal hemorrhoid symptoms and external hemorrhoid symptoms
Hemorrhoid ointment works immediately to protect against further irritation
Hemorrhoid treatment formula temporarily shrinks swollen hemorrhoidal tissue
Use with Preparation H Medicated Wipes to cool, soothe and cleanse before you treat, for better hemorrhoid relief
Preparation H is the doctor recommended brand for hemorrhoid treatment
HSA and FSA eligible product
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
One 1.8 Ounce tube
delivers fast pain relief
provides soothing relief
releives skin irritation
use wipes before cream
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
One box of wipes
Maximum strength
Relieves itch
Use as needed
Cools and soothes
HSA and FSA eligible product
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Includes two 18 Ounce tubes of Preparation H Maximum Strength Hemorrhoid Pain Relief cream
The only over the counter hemorrhoid treatment cream with maximum strength pramoxine for multi-symptom relief
Proprietary hemorrhoid cream blend with vitamin E, panthenol and soothing aloe
Provides rapid hemorrhoid relief from pain, burning, itching and discomfort
Preparation H cream rapidly relieves external hemorrhoid symptoms
Hemorrhoid treatment formula shrinks swollen hemorrhoidal tissue
Use with Preparation H Medicated Wipes to cool, soothe and cleanse before you treat for better hemorrhoid relief
Preparation H is the no.1 doctor recommended brand for hemorrhoid treatment
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Soapify | 9.72 | ❌ | ❌ | ❌ |
One 1 oz tube of Preparation H Rapid Relief Hemorrhoid Cream with Lidocaine
Hemorrhoid treatment delivers fast relief of pain, itching and burning caused by external hemorrhoids
Numbing cream formulated with lidocaine to numb skin and glycerin help promote skin healing
Itch relief cream helps temporarily relieve skin irritation associated with hemorrhoids
For better relief, Preparation H Medicated Wipes can be used before applying Preparation H Rapid Relief with Lidocaine Cream
Hemorrhoid relief from the number 1 doctor recommended brand for hemorrhoid treatment (1)
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
One 1.8 oz tube of Preparation H Hemorrhoid Cooling Gel with Aloe
External hemorrhoid treatment delivers fast hemorrhoid pain relief, as well as itching and burning relief
Hemorrhoid symptom treatment formulated with aloe and vitamin E for a soothing gel
Hemorrhoid itch treatment helps temporarily relieve skin irritation associated with hemorrhoids
Preparation H Medicated Wipes can be used before applying Preparation H Hemorrhoid Gel
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
One 0.9 oz tube of Preparation H Hemorrhoid Cooling Gel with Aloe
External hemorrhoid treatment delivers fast hemorrhoid pain relief, as well as itching and burning relief
Hemorrhoid symptom treatment formulated with aloe and vitamin E for a soothing gel
Hemorrhoid itch treatment helps temporarily relieve skin irritation associated with hemorrhoids
Preparation H Medicated Wipes can be used before applying Preparation H Hemorrhoid Gel
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| BetterNutrition | 9.95 | ✅ | ✅ | ✅ |
Two 2.7 ounce bottles of Preparation H Soothing Relief Cooling Spray, Witch Hazel Spray for Irritated Skin Relief
Cools irritated skin, offering fast, targeted hemorrhoid relief of burning and itching
Cooling spray for quick and easy irritated skin relief that is gentle enough for daily use
Witch hazel spray that's non-messy and easy to apply at any angle without touching the irritated area
Take this portable witch hazel spray bottle with you for relief on the go
This hemorrhoidal spray is the newest addition to our Soothing Relief line, which also includes Preparation H Soothing Relief Cleansing and Cooling Wipes
Use as directed
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| iTrifecta | 9.95 | ✅ | ✅ | ✅ |
🟢 GENTLE SOOTHING: Globe Hemorrhoid Cream focuses on relieving hemorrhoids as comfortably possible. We use fast numbing action to reduce itching, burning caused by Hemorroids. We use natural soothing aloe vera to help keep skin healthy while reducing swelling.
🟢 RELIEF AND PROTECTION: This hemorrhoid product uses Phenylephrine HCl, Pramoxine HCl, and White Petrolatum to reduce size and soothe Hemorroidal symptoms while numbing. Our formula uses glycerol to form a protective layer around the hemorrhoid to guard against friction.
🟢 EFFECTIVE RELIEF: Globe's Hemorrhoid Ointment relieves symptoms for both internal and external hemorrhoids and piles. The soothing creme gives relief from swelling, flare-ups, and discomfort. Just compare our active ingredients to Preparation H.
🟢 FASTER AND EASIER: Globe Hemorrhoid Cream acts quicker with ingredients formulated to penetrate deep and take action faster. You can add the creme to wipes, applicators, or just use a finger for external hemorrhoids.
🟢 FIRST-AID ESSENTIALS: Globe's Hemorrhoid Cream is a must have for any First-Aid Kit or Medicine Cabinet. This medicated cream is perfect for even the most sensitive cases and gives relief faster. We cut out unnecessary fillers and deliver effective results.
🟢 WHATS INSIDE: Phenylephrine HCl, Glycerol, Pramoxine HCl, and White Petrolatum. Compare to the Active Ingredients of Preparation H Hemorrhoid Cream.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| iTrifecta | 9.95 | ✅ | ✅ | ✅ |
🟢 GENTLE SOOTHING: Globe Hemorrhoid Cream focuses on relieving hemorrhoids as comfortably possible. We use fast numbing action to reduce itching, burning caused by Hemorroids. We use natural soothing aloe vera to help keep skin healthy while reducing swelling.
🟢 RELIEF AND PROTECTION: This hemorrhoid product uses Phenylephrine HCl, Pramoxine HCl, and White Petrolatum to reduce size and soothe Hemorroidal symptoms while numbing. Our formula uses glycerol to form a protective layer around the hemorrhoid to guard against friction.
🟢 EFFECTIVE RELIEF: Globe's Hemorrhoid Ointment relieves symptoms for both internal and external hemorrhoids and piles. The soothing creme gives relief from swelling, flare-ups, and discomfort. Just compare our active ingredients to Preparation H.
🟢 FASTER AND EASIER: Globe Hemorrhoid Cream acts quicker with ingredients formulated to penetrate deep and take action faster. You can add the creme to wipes, applicators, or just use a finger for external hemorrhoids.
🟢 FIRST-AID ESSENTIALS: Globe's Hemorrhoid Cream is a must have for any First-Aid Kit or Medicine Cabinet. This medicated cream is perfect for even the most sensitive cases and gives relief faster. We cut out unnecessary fillers and deliver effective results.
🟢 WHATS INSIDE: Phenylephrine HCl, Glycerol, Pramoxine HCl, and White Petrolatum. Compare to the Active Ingredients of Preparation H Hemorrhoid Cream.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| VIP Beauty Shop | 9.76 | ✅ | ✅ | ✅ |
For soothing and relies on the skin in the anal area
Cloth Wipes, Especially Soft & Moist
Contains herbal essential oils, herbal extracts and Vitamins E & B5
Especially effective when used jointly with Presto Gel cream, Presto Gel suppositories & Presto Gel liquid soap
Suitable for the everyday feminine hygiene - external vaginal care
Here is the list of top-rated brands that were evaluated by PM.
| Brand | Count |
|---|---|
| Preparation H | 9 |
| Globe | 2 |
| Presto Gel | 1 |
We've carried out a comprehensive analysis of 58,806 reviews on hemorrhoid gels, using our selection criteria to identify the best options in the bedding. Our findings reveal that most customers typically select hemorrhoid gels priced around $12.45, with top brands including dr. frederick's original, preparation h, natureplex, magic gel, hemorrwedge, simplyvital, presto gel, cherioll and amazon basic care and hemorrhoidal ointment
Our team of expert editors reviewed these high-quality items and handpicked the top 12 hemorrhoid gels for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the bedding category. These include frederick medical supply, amazon.com, dropped price sales, stretton online, hemorrwedge, premier prime outlet, alpha plants inc, vip beauty shop and auspicious-us and itrifecta .
We are dedicated to assisting our users in finding the right products Products based on their needs, saving them considerable time when choosing which hemorrhoid gels to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.
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