Best Osmotic Laxatives in 2026

Daisy
Last Updated: Feb 9, 2026

At a Glance: Our Top Picks for Osmotic Laxatives

Amazon Basic Care ClearLax, Polyethylene Glycol 3350 Powder for Solution, Osmotic Laxative, 17.9 Ounces
#TOP1
Amazon Basic Care Clearlax, Polyethylene Glycol 3350 Powder
9.9
PM SCORE
Fleet Children's Pedia-Lax Liquid Glycerin Suppositories -- 6 Suppositories
#TOP2
Fleet Children's Pedia-Lax Liquid Glycerin Suppositories -- 6
9.9
PM SCORE
GoodSense ClearLax, Polyethylene Glycol 3350 Powder for Solution, Osmotic Laxative, 17.9 Ounce
#TOP3
Goodsense Clearlax, Polyethylene Glycol 3350 Powder For Solution,
9.8
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Osmotic Laxatives of 2026

Market Overview
Osmotic Laxatives Reviewed
  • Reviews Analyzed: 44057 Items
  • PM Avg. Rating: 9.0 / 10
20 Products Evaluated
  • Highest Price: $39.60
  • Lowest Price: $7.12
  • Avg. Price: $15.40

Amazon Basic Care Clearlax, Polyethylene Glycol 3350 Powder For Solution, Osmotic Laxative, 17.9 Ounces

AMAZON BASIC CARE
306D8
3.18 X 4.25 X 7.00 Inches
1.30 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: The active ingredient of this osmotic laxative is Polyethylene Glycol 3350. Compare to MiraLAX active ingredient

OSMOTIC LAXATIVE: Amazon Basic Care ClearLax Polyethylene Glycol 3350 Powder for Solution acts as a laxative used to relieve occasional constipation/irregularity. The laxative generally produces a bowel movement in 1 to 3 days

RELIEF FOR IRREGULARITY: Amazon Basic Care ClearLax Polyethylene Glycol 3350 Powder for Solution increases frequency of bowel movements and softens the stool; relieves occasional constipation (irregularity).

UNFLAVORED POWDER: Unflavored laxative powder dissolves in any beverage. Grit free, sugar free and gluten free. For adults and children 17 years of age and older.

Polyethylene Glycol 3350 is the #1 Doctor Recommended Laxative Active Ingredient (Of U.S. physicians surveyed by an independent market research firm, excluding Therapeutic Fiber and Stool Softeners)

Fleet Children's Pedia-Lax Liquid Glycerin Suppositories -- 6 Suppositories

FLEET
106690
1.80 X 2.90 X 3.14 Inches
0.04 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Uniquely formulated for kids ages 2-5

Provides gentle relief in minutes

Predictable glycerin-based suppository won't upset your child's digestive system

Goodsense Clearlax, Polyethylene Glycol 3350 Powder For Solution, Osmotic Laxative, 17.9 Ounce

GOODSENSE
370030149162-1
3.71 X 3.71 X 6.95 Inches
1.30 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: The active ingredient of this osmotic laxative is Polyethylene Glycol 3350 Compare to MiraLAX active ingredient

OSMOTIC LAXATIVE: GoodSense ClearLax Polyethylene Glycol 3350 powder for solution acts as a laxative used to relieve occasional constipation/irregularity. The laxative generally produces a bowel movement in 1 to 3 days

RELIEF FOR IRREGULARITY: GoodSense ClearLax Polyethylene Glycol 3350 Powder for Solution increases frequency of bowel movements and softens the stool; Relieves occasional constipation (irregularity)

UNFLAVORED POWDER: Unflavored laxative powder dissolves in any beverage Grit free, sugar free and gluten free; For adults and children 17 years of age and older

Polyethylene Glycol 3350 is the number 1 Doctor Recommended Laxative Active Ingredient (Of US physicians surveyed by an independent market research firm, excluding Therapeutic Fiber and Stool Softeners)

Perrigo Polyethylene Glycol 3350 17.9 Oz (510Gm) Powder (Compare To Miralax)

PERRIGO
ASINPPOBTYO9842
1.12 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
PHARMCO 9.95

Features

OSMOTIC LAXATIVE

RELIEVES OCCASIONAL CONSTIPATION (IRREGULARITY)

SOFTENS STOOL

30 ONCE DAILY DOSES

DISSOLVES IN ANY BEVERAGE, SUGAR FREE

Pedia-Lax Enema - 2.25 Oz - 6 Ct

FLEET
190B
3.20 X 2.85 X 1.75 Inches
0.14 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Fenny World Store Ship Internationally Thank You

Country Of Origin: United States

Item Package Dimension: 3.25" L x 3.0" W x 2.0" H

Item Package Weight: 2.3 oz

Nature’s Way Cascara Sagrada Bark, Occasional Constipation Relief*, Non-Gmo Project Verified, 270 Mg Per Serving, 180 Capsules

NATURE'S WAY
11308
2.59 X 2.59 X 5.15 Inches
0.26 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Provides occasional constipation relief.*

Cascara sagrada bark has been used for hundreds of years for various purposes. It is also known as “sacred bark” and “chittem bark.”

Trusted quality. This product is Non-GMO Project Verified.

Gluten-free and vegan. No salt, yeast-derived ingredients, wheat, soy, corn, dairy, or artificial colors, flavors, or preservatives.

Responsible packaging. Bottle made with 97% post-consumer recycled materials. Please recycle.

Prunelax Ciruelax Natural Laxative Regular Liquid For Kids, For Occasional Constipation, 4.05 Fl Oz

PRUNELAX
EX1492
2.76 X 3.15 X 2.36 Inches
0.08 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Perfect product for children because it's very easy to swallow and has a great taste.

Prunelax Ciruelax for kids is an effective natural laxative that contains natural fruit juice and senna extract which relieves occasional constipation and helps maintain bowel regularity.

Each 5 ml dose contains 7.5 mg of sennosides B

Daily dosage: Children from 4 to 5: 2,5 to 5 ml / Children from 6 to 12: 5 to 10 ml / Children over 12: 20 ml

Provides gentle overnight relief

Easy to Take

Prunelax Ciruelax is a predictable and effective solution that works in just 8 to 12 hours, providing gentle overnight relief from constipation.

This product is 100% gluten-free.

Miralax Single Dose Sachets, 10 Count

MIRALAX
1.77 X 3.35 X 4.33 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
VerSure 9.98

Features

Miralax is gluten and sugar free

No bloating

No cramping

No sudden urges

Amazon Basic Care Clearlax, Polyethylene Glycol 3350 Powder For Solution, Osmotic Laxative, Unflavored, 0.5 Ounce Each, 10 Count (Pack Of 1)

AMAZON BASIC CARE
2.69 X 4.00 X 6.19 Inches
0.04 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: The active ingredient of this osmotic laxative is Polyethylene Glycol 3350. Compare to MiraLAX active ingredient.

OSMOTIC LAXATIVE: Amazon Basic Care ClearLax Polyethylene Glycol 3350 Powder for Solution acts as a laxative used to relieve occasional constipation/irregularity. The laxative generally produces a bowel movement in 1 to 3 days

RELIEF FOR IRREGULARITY: Amazon Basic Care ClearLax Polyethylene Glycol 3350 Powder for Solution increases frequency of bowel movements and softens the stool; relieves occasional constipation (irregularity).

UNFLAVORED POWDER: Unflavored laxative powder dissolves in any beverage. Grit free, sugar free and gluten free. For adults and children 17 years of age and older.

Polyethylene Glycol 3350 is the #1 Doctor Recommended Laxative Active Ingredient (Of U.S. physicians surveyed by an independent market research firm, excluding Therapeutic Fiber and Stool Softeners)

Goodsense Clearlax, Polyethylene Glycol 3350 Powder For Solution, Osmotic Laxative, 8.3 Ounce

GOOD SENSE
14915
2.26 X 3.30 X 6.26 Inches
0.52 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: The active ingredient of this osmotic laxative is Polyethylene Glycol 3350 Compare to MiraLAX active ingredient

OSMOTIC LAXATIVE: GoodSense ClearLax Polyethylene Glycol 3350 Powder for Solution acts as a laxative used to relieve occasional constipation/irregularity The laxative generally produces a bowel movement in 1 to 3 days

RELIEF FOR IRREGULARITY: GoodSense ClearLax Polyethylene Glycol 3350 Powder for Solution increases frequency of bowel movements and softens the stool; relieves occasional constipation (irregularity)

UNFLAVORED POWDER: Unflavored laxative powder dissolves in any beverage Grit free, sugar free and gluten free For adults and children 17 years of age and older

Polyethylene Glycol 3350 is the #1 Doctor Recommended Laxative Active Ingredient (Of US physicians surveyed by an independent market research firm, excluding Therapeutic Fiber and Stool Softeners)

Phillips' Fresh Mint Milk Of Magnesia Liquid,26 Fl Oz (Pack Of 2)

PHILLIPS'
306
6.00 X 4.00 X 5.00 Inches
3.75 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Pattern Products 9.95

Features

Pack of two, 26-ounce bottle

Relieves occasional constipation

(total of 52-ounces)

The package dimension of the product is 6"L x 4"W x 5"H

Miralax 14Dose Oz (238G) Powder 8.3 Ounce

MIRALAX
82073
2.80 X 2.80 X 6.00 Inches
0.52 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Medikus 9.77

Features

UNBLOCK YOUR SYSTEM: MiraLAX, an osmotic laxative, works naturally with the water in your body to hydrate, soften, and ease stool through your colon in 1-3 days. Other stimulant laxatives stimulate the nerves to move stool through the colon

NO HARSH SIDE EFFECTS: MiraLAX helps relieve your occasional constipation without causing gas, bloating, cramping, or sudden urgency

#1 PHYSICIAN RECOMMENDED: Since going on the market as an OTC laxative in 2007, MiraLAX has been the #1 Physician Recommended OTC brand of laxative

HOW TO USE: Fill bottle cap to the indicated line (white section in cap) and pour into 4 to 8 ounces of hot or cold beverage. Mix until the powder is fully dissolved and drink. MiraLAX has no added taste or grit

FREE FROM: Gluten, sugar, and preservatives

Fleet Saline Enema, 4 Count And Fleet Laxative Liquid Glycerin Suppositories For Adult Constipation Relief | 4 Ct | 3 Pack

FLEET
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Ready to use, disposable squeeze bottle with a soft, pre lubricated Comfortis

Ideal for bowel cleansing prior to a rectal examination

Works without pain or spasm

Liquid suppository for occasional constipation relief

Osmotic laxative; works with the water in your body

Gentle relief in minutes

Perrigo Polyethylene Glycol 3350 8.3 Oz (238Gm) Powder (Compare To Miralax)

PERRIGO
345802868022
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
CareMartOTC 9.91

Features

Osmotic laxative

Relieves occasional constipation (irregularity)

Softens stool

Original Prescription strength

14 daily doses, sugar free

Phillips' Milk Of Magnesia Overnight Relief Of Occasional Constipation Liquid Laxative - Original Flavor- 26 Fl Oz Bottle, Pack Of 4

PHILLIPS'
303
6.00 X 6.00 X 5.10 Inches
6.00 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Pattern Products 9.95

Features

Trusted brand: Phillips' has over 140 years of trusted digestive health expertise

Gentle and effective overnight relief: Formulated with Magnesium Hydroxide, Phillips' Milk of Magnesia offers cramp-free, gentle overnight relief of occasional constipation without the use of harsh stimulants

Variety of flavors: This classic, medicine-cabinet standard is available in three liquid flavors: Original, Wild Cherry, and Fresh Mint

Phillips' is the 1 Milk of Magnesia brand

Gericare Sorbitol Solution, 16 Fl Oz

GERICARE
SPPPOA045475
2.00 X 4.00 X 8.00 Inches
1.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Moofin 9.87

Features

Product Type:Health Personal Care

Item Package Dimension:4.9 cm L X7.6 cm W X19.5 cmh

Item Package Weight:1.5 lbs

Country Of Origin: United States

Sorbitol Solution Usp 70% W/W Laxative ,16 Oz. (473Ml)

MCKESSON
57896043516
6.61 X 4.06 X 2.80 Inches
1.00 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Atlantic Pharma Co 9.95

Features

Soritol

357896435165

McKesson

Health & Personal Care > Health Care > Medications & Treatments > Digestion & Nausea > Laxatives

Movicol Sachets For Relieve Of Constipation To Restore Comfortable Bowel Movements - Lemon - Lime Flavor - 30 Sachets

MOVICOL
AUST R 60786
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Global Convenience Co 9.88

Features

EFFECTIVE RELIEF: Movicol is popularly-known for its effective results against long-time chronic constipation and faecal impaction.

HIGH-QUALITY: These powder sachets contain fast-acting laxative made from premium ingredients, such as acacia solids, maltodextrin, lime oil, lemon oil, citral, and citric acid.

PLEASANT FLAVOUR: The lime and lemon flavours and ingredients like acacia solids, lime oil, and lemon oil are not only enriched with antioxidants but also make these movicol sachets pleasant to consume.

VEGAN-FRIENDLY: The movicol powder is made with a premium composition that is dairy-free, gluten-free, and sucrose-free. This makes these sachets all the more reliable for effective results.

DIRECTIONS OF USE: Oral consumption of these effective laxatives include one sachet in 125mL water for constipation while certain intestinal disorders, 8 sachets may be dissolved in 1 litre of water and consumed within 6 hours.

Rugby Polyethylene Glycol (Peg) 3350 Osmotic Laxative Sugar-Free Unflavored Grit Free Powder 8.3 Oz - 14 Once-Daily Doses

SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
xeteor 9.92

Features

Compare to the active ingredient in the leading osmotic laxative brand

Polyethylene Glycol 3350 17 g (cap filled to the line) - Osmotic Laxative

Relieves occasional constipation (irregularity) / Softens stool

Unflavored Grit Free Powder - 14 Once-Daily Doses

Sugar-Free

Phillips' Laxative Caplets (24-Count Box), Multi (Pack Of 3)

PHILLIPS'
B001G7QIFW
0.31 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

The below information is per pack only

Phillips' Laxative Caplets are a convenient, easy-to-swallow laxative supplement that works with the body's natural process to gently relieve occasional constipation.*

Formulated with Magnesium Oxide, Phillips' Laxative Caplets offer gradual, cramp-free, gentle relief of occasional constipation.*

Does not contain harsh stimulants, helping you get back to regular with comfortable relief.

Phillips’ has over 140 years of trusted digestive health expertise.

This product ships as one 24-count box.

Top 10 laxatives osmotic Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Fleet 3
Phillips' 3
Amazon Basic Care 2
Miralax 2
Perrigo 2
1
Gericare 1
Good Sense 1
Goodsense 1
Mckesson 1

Top 10 laxatives osmotic Brands Pie Chart


We've carried out a comprehensive analysis of 44,057 reviews on laxatives osmotic, using our selection criteria to identify the best options in the categories. Our findings reveal that most customers typically select laxatives osmotic priced around $15.40, with top brands including and

Our team of expert editors reviewed these high-quality items and handpicked the top 20 laxatives osmotic for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the categories category. These include and .

We are dedicated to assisting our users in finding the right laxatives Products based on their needs, saving them considerable time when choosing which laxatives osmotic to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.