Best Dimetapp Medicine in 2026

Daisy
Last Updated: Jul 18, 2026

At a Glance: Our Top Picks for Dimetapp Medicine

Sudafed PE Sinus Pressure + Pain Relief Maximum Strength Non-Drowsy Decongestant, 24 Count
#TOP1
Sudafed Pe Sinus Pressure + Pain Relief Maximum
9.9
PM SCORE
GoodSense Maximum Strength Nasal Decongestant PE, Phenylephrine HCl 10 mg, Sinus Congestion Relief; Relieves Nasal Congestion Due to Hay Fever, Common Cold and Upper Respiratory Allergies, 72 Count
#TOP2
Goodsense Maximum Strength Nasal Decongestant Pe, Phenylephrine Hcl
9.9
PM SCORE
Sudafed Nasal Spray
#TOP3
Sudafed Nasal Spray
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Dimetapp Medicine of 2026

Sudafed Pe Sinus Pressure + Pain Relief Maximum Strength Non-Drowsy Decongestant, 24 Count

SUDAFED
JJ-2314
0.63 X 2.91 X 4.52 Inches
0.05 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

24-count box of Sudafed PE Sinus Pressure + Pain Relief Maximum Strength Non-Drowsy Decongestant Tablets provide powerful relief of sinus pain, sinus pressure, nasal congestion and headaches

Each caplet contains 5 milligrams of the decongestant phenylephrine HCl and 325 milligrams of acetaminophen, a pain reliever and fever reducer

This sinus congestion & pain medicine also temporarily relieves nasal congestion associated with hay fever, upper respiratory allergies and the common cold

The non-drowsy decongestant helps promotes sinus drainage, temporarily reduces fever and helps relieve headaches and minor aches and pain

From the #1 pharmacist recommended brand among oral OTC decongestants, this maximum strength formula can be used by adults and children 12 years and older for powerful symptom relief

Goodsense Maximum Strength Nasal Decongestant Pe, Phenylephrine Hcl 10 Mg, Sinus Congestion Relief; Relieves Nasal Congestion Due To Hay Fever, Common Cold And Upper Respiratory Allergies, 72 Count

GOOD SENSE
370030147403-1
3.25 X 1.00 X 4.38 Inches
0.09 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: The active ingredient in GoodSense Maximum Strength Nasal Decongestant PE is phenylephrine HCl 10 mg, a nasal decongestant, which compares to the active ingredient in Sudafed PE Congestion

NASAL DECONGESTANT: This product provides maximum strength, non-drowsy relief for nasal and sinus congestion, and sinus pressure due to the common cold, hay fever or other upper respiratory allergies

MAXIMUM STRENGTH: GoodSense Maximum Strength Nasal Decongestant PE provides maximum strength relief for sinus pressure, nasal and sinus congestion

NON-DROWSY relief so you can power through your day

ASPIRIN AND GLUTEN FREE. GoodSense Maximum Strength Nasal Decongestant PE, Phenylephrine HCl, 10 mg does not contain pseudoephedrine

Sudafed Nasal Spray

SUDAFED
106445500
3.94 X 1.18 X 1.18 Inches
0.11 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Subha Enterprise 9.94

Features

Nose spray

Unblocks your nose fast

Lasts up to 10 hours

Non-drowsy

Metered spray

Sudafed Children's Pe Nasal Decongestant, Liquid Cold Relief Medicine With Phenylephrine Hcl, Alcohol Free And Sugar-Free, Berry-Flavored, 4 Fl. Oz

SUDAFED
JJ-765
6.00 X 5.00 X 4.00 Inches
0.04 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

4-fluid ounces of Children's Sudafed PE Nasal Decongestant provides temporary relief for children's nasal congestion and sinus pressure due to the common cold and hay fever

Non-drowsy nasal decongestant formula that is alcohol-free and sugar-free and includes the active ingredient of phenylephrine HCl as a nasal decongestant

Find both sinus pressure and nasal congestion relief with this cold medicine for kids ages 4-11 with a non-drowsy formula

Non-drowsy relief of nasal congestion from the common cold and allergies in a kid-friendly berry flavor suitable for ages 4 to 11

Cold medicine for kids ages 4-11 in a 4-fluid ounce bottle to help relieve both sinus pressure and nasal congestion

Sudafed Pe Non-Drowsy Head Congestion + Pain Relief Caplets With Ibuprofen 200 Mg & Phenylephrine Hcl 10 Mg, Nasal Decongestant & Nsaid Pain Reliever & Fever Reducer, 20 Ct

SUDAFED
55120
1.00 X 3.00 X 4.38 Inches
0.05 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

20-count of Sudafed PE Non-Drowsy Head Congestion + Pain Relief Caplets for effective nasal congestion relief and nasal swelling relief, now coupled with the powerful pain relief of ibuprofen

From the #1 pharmacist recommended brand among oral OTC decongestants, it provides non-drowsy relief from head congestion and pain symptoms caused by head colds

Each coated caplet contains 200 milligrams of ibuprofen, the #1 doctor-recommended pain reliever, to help reduce fever while also helping to alleviate headache and minor body aches and pains

Each coated caplet also contains 10 milligrams of phenylephrine HCl nasal decongestant to relieve sinus pressure and nasal congestion by helping to reduce nasal passage swelling and temporarily restoring freer breathing through the nose

This decongestant medicine can be used by adults and children 12 years and older and provides nasal congestion relief with the pain-relieving benefits of ibuprofen

Amazon Basic Care Sinus Pe, Maximum Strength Nasal Decongestant, Cold Medicine, Phenylephrine Hcl Tablets, 10 Mg, 36 Count

AMAZON BASIC CARE
1.00 X 4.38 X 3.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: The active ingredient in Amazon Basic Care Nasal Decongestant PE is Phenylephrine HCl 10 mg, a nasal decongestant, which compares to the active ingredient in Sudafed PE Congestion

NASAL DECONGESTANT: This product provides maximum strength, non-drowsy relief for nasal and sinus congestion, and sinus pressure due to the common cold, hay fever or other upper respiratory allergies

MAXIMUM STRENGTH: This nasal decongestant provides powerful relief for sinus pressure, nasal and sinus congestion

NON-DROWSY: These tablets offer non-drowsy relief so you can power through your day

ASPIRIN AND GLUTEN FREE: Amazon Basic Care Maximum Strength Nasal Decongestant PE is aspirin and gluten free

Sudafed Pe Day And Night Sinus Pressure & Congestion Tablets, 20 Count

SUDAFED
503835
0.64 X 4.56 X 2.88 Inches
0.04 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

20-count of Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant Medicine Tablets to temporarily relieve sinus pressure and sinus congestion for both day and night

Each multi-pack contains 20 tablets of nasal decongestant, with 12 Daytime and 8 Nighttime tablets for powerful symptom relief throughout the day and while you sleep

Each daytime and nighttime dose contains 10 milligrams of the nasal decongestant phenylephrine HCl per tablet and each nighttime dose also contains 25 milligrams per tablet of the antihistamine diphenhydramine HCl

Both formulas help relieve sinus pressure and sinus congestion, and nasal congestion due to the common cold, hay fever, or upper respiratory allergies. Nighttime tablets also relieve sneezing, runny nose, itchy, watery eyes and itchy throat or nose

From the #1 pharmacist recommended brand among oral OTC decongestants, this maximum-strength formula can be used by adults and children 12 years and older for powerful symptom relief

Sudafed Pe Head Congestion + Mucus Relief Tablets For Sinus Pressure, Congestion, & Headache, Non-Drowsy Decongestant With Acetaminophen, Guaifenesin & Phenylephrine Hci, 24 Ct

SUDAFED
300450580252
0.75 X 4.44 X 2.88 Inches
0.07 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
westlake 9.87

Features

24-count box of Sudafed PE Head Congestion + Mucus Tablets to provide non-drowsy relief from sinus pain and pressure, nasal & chest congestion, and excess mucus

Sinus relief medicine contains 5 mg of phenylephrine HCl, a decongestant, for congestion relief and 325 mg of acetaminophen for pain and fever reduction. Also has 200 mg of guaifenesin, an expectorant, for mucus reduction

Head congestion tablets temporary relieves symptoms associated with hay fever, upper respiratory allergies, and the common cold

Non-drowsy decongestant tablets provide relief of sinus pressure, headaches, nasal and chest congestion, excess mucus, and minor aches and pains

Head congestion relief medicine also helps loosen mucus to clear bronchial passageways and make coughs more productive. Get powerful head congestion relief from the #1 pharmacist recommended brand among oral OTC decongestants.

#TOP9

Sudafed Pe Sinus Congestion Maximum Strength Non-Drowsy Decongestant Tablets, 36 Ct

SUDAFED
YO580
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Cloud-Kart Inc. 9.83

Features

36-count of Sudafed PE Sinus Congestion Maximum Strength Non-Drowsy Tablets for fast, powerful relief of sinus pressure and sinus and nasal congestion

Each coated tablet contains 10 milligrams of phenylephrine HCl, a nasal decongestant that provides non-drowsy symptom relief

The maximum strength formula helps clear sinus congestion and relieve sinus pressure due to the common cold, hay fever or other upper respiratory allergies

This sinus congestion & pressure relief medicine also helps reduce nasal swelling to help you breathe easier, and can be taken every 4 hours as necessary for effective relief of cold and allergy symptoms

From the #1 pharmacist recommended brand among oral OTC decongestants, this non-drowsy decongestant can be used by adults and children 12 years and older for fast, powerful relief

Goodsense Maximum Strength Nasal Decongestant Pe, Phenylephrine Hcl 10 Mg, Sinus Congestion Relief; Relieves Nasal Congestion Due To Hay Fever, Common Cold And Upper Respiratory Allergies, 36 Count

GOODSENSE
370030147410
3.25 X 1.00 X 4.38 Inches
0.07 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENT: The active ingredient in GoodSense Maximum Strength Nasal Decongestant PE is phenylephrine HCl 10 mg, a nasal decongestant, which compares to the active ingredient in Sudafed PE Congestion

NASAL DECONGESTANT: This product provides maximum strength, non-drowsy relief for nasal and sinus congestion, and sinus pressure due to the common cold, hay fever or other upper respiratory allergies

MAXIMUM STRENGTH: GoodSense Maximum Strength Nasal Decongestant PE provides maximum strength relief for sinus pressure, nasal and sinus congestion

NON-DROWSY relief so you can power through your day

ASPIRIN AND GLUTEN FREE. GoodSense Maximum Strength Nasal Decongestant PE, Phenylephrine HCl, 10 mg does not contain pseudoephedrine

Medique 80964 Medi-First Sinus Decongestant, 24 Tablets

MEDIQUE
80964
6.50 X 4.00 X 7.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

A non-drowsy formula that quickly clears sinus pressure and nasal congestion

Each tablet contains: Phenylephrine HCl 10mg

Compare active ingredient to Sudafed PE

24 tablets, 24 packets each contain 1 tablet

Children's Sudafed Pe Cold + Cough Suppressant, Cold Medicine & Nasal Decongestant, Grape Flavor Liquid Cough Relief, 4 Fl. Oz

SUDAFED
4.22 X 4.15 X 5.22 Inches
1.63 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Silver fox 1 8.96

Features

4-fluid ounces of Children's Sudafed PE Cold + Cough cold medicine for kids temporarily relieves various symptoms due to common cold, hay fever, and other upper respiratory allergies

Contains a cough suppressant, dextromethorphan HBr, and a nasal decongestant, phenylephrine HCl for multi symptom cold and cough relief for your children aged 4 and up

Non-drowsy, multi-symptom cold medicine for kids with a kid-friendly grape flavor

Children's cough suppressant and nasal decongestant for relieving cold and upper respiratory allergies symptoms, including stuffy nose, nasal congestion, sinus pressure and cough

Alcohol-free and sugar-free liquid cough relief intended for ages 4 & up formula in a 4-fluid ounce bottle

Top 10 medicine Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Sudafed 8
Amazon Basic Care 1
Good Sense 1
Goodsense 1
Medique 1

Top 10 medicine Brands Pie Chart


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