Best 365 By Whole Foods Market Vitamin B Supplements in 2026

Daisy
Last Updated: Jul 19, 2026

At a Glance: Our Top Picks for 365 By Whole Foods Market Vitamin B Supplements

Designs for Health Zinc Supreme - 30mg Zinc Bisglycinate Chelate Supplement with Cofactors Taurine, Vitamin B6, B2 + Molybdenum - Immune Support Supplement - Vegan + Non-GMO (90 Capsules)
#TOP1
Designs For Health Zinc Supreme - 30Mg Zinc
9.8
PM SCORE
designs for health Vitamin D Supreme - Vitamin D3 5000 IU with 2000mcg Vitamin K for Bone, Cardiovascular + Immune Health - K2 Vitamin + VIT D3 Enhanced with GG Supplement (180 Capsules)
#TOP2
Designs For Health Vitamin D Supreme - Vitamin
9.8
PM SCORE
Designs for Health Vitamin B12 Lozenges - 5000mcg B12 Methylcobalamin Methyl B12 - Vegan Vitamin B12 Supplements - Non GMO, Natural Berry Flavor (60 Quick Dissolve Lozenges)
#TOP3
Designs For Health Vitamin B12 Lozenges - 5000Mcg
9.7
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best 365 By Whole Foods Market Vitamin B Supplements of 2026

Market Overview
365 By Whole Foods Market Vitamin B Supplements Reviewed
  • Reviews Analyzed: 4978 Items
  • PM Avg. Rating: 9.0 / 10
14 Products Evaluated
  • Highest Price: $124.99
  • Lowest Price: $21.49
  • Avg. Price: $54.47

Designs For Health Zinc Supreme - 30Mg Zinc Bisglycinate Chelate Supplement With Cofactors Taurine, Vitamin B6, B2 + Molybdenum - Immune Support Supplement - Vegan + Non-Gmo (90 Capsules)

DESIGNS FOR HEALTH
879452000964
4.00 X 3.00 X 5.33 Inches
0.29 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

Support Immune Health - Zinc is essential for growth and physical development, and for the immune system. Most aspects of reproduction in both males and females require zinc.*

Unique Formula - Zinc Supreme contains Zinc, Molybdenum, Vitamin B-6, Riboflavin, Taurine and Malic Acid. *

Ideal Mineral Technology - Ideal chelates for optimal absorption, by Albion Advanced Nutrition, the leader in mineral technology. These minerals are combined with other nutrients like vitamins B6 and taurine to provide superior results.*

Higher Standards. Better Results - Designs for Health maintains a strict, no-compromises approach to quality raw material selection. We never cut corners with substandard ingredients. This product is Non-GMO, Gluten-Free, and Vegetarian-friendly.

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Vitamin D Supreme - Vitamin D3 5000 Iu With 2000Mcg Vitamin K For Bone, Cardiovascular + Immune Health - K2 Vitamin + Vit D3 Enhanced With Gg Supplement (180 Capsules)

DESIGNS FOR HEALTH
879452002999
3.00 X 3.00 X 4.00 Inches
0.16 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

Upgrade Your Vitamin D K - Each small easy-swallow capsule features clinically relevant amounts of bioavailable vitamin d3 (5000 IU), combined with 2000 mcg of vitamin K1 and K2. GG is also included as a complementary bone and immune supportive compound.* (Note: This product has been reformulated to include more vitamin K and GG).

Featuring a Superior K2 Form - This vitamin k1 k2 supplement features vitamin k2 mk-4, a premium form of vit k. Vitamins D and K work synergistically, thus, increasing vitamin D increases the need for vitamin K.

Why Add GG to Vitamin D? Geranylgeraniol is a compound produced naturally in the body that declined with age. It is included in this vitamin d complex to help promote optimal bone and heart health, maintain proper immune system balance and vitamin K status.

Immune, Bone + Cardiovascular Support - Vitamin d3 with k can support optimal bone health, cardiovascular health, and help maintain healthy immune system balance.*

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements and vitamin D supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Vitamin B12 Lozenges - 5000Mcg B12 Methylcobalamin Methyl B12 - Vegan Vitamin B12 Supplements - Non Gmo, Natural Berry Flavor (60 Quick Dissolve Lozenges)

DESIGNS FOR HEALTH
DF0334
2.25 X 3.00 X 4.00 Inches
0.04 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

Delicious, Activated B12 - Each lozenge supplies 5000 mcg methylcobalamin (the 'active' form of B12) in a delicious berry flavored tablet.*

Convenient Lozenge Form - Dissolve one lozenge slowly in mouth per day, or as directed by your health care practitioner.

Unique Delivery System - Designed to deliver B12 through the mucous membranes in order to bypass the need for intrinsic factor, a protein produced in the stomach needed for maximal GI absorption of B12.

Always Pure & Effective Products - This product is Vegetarian-Friendly, Non-GMO and contains No Gluten, Dairy, or Soy. Eco-conscious, tinted glass bottles offer a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.*

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Dfh Complete Multi - Comprehensive Multi Vitamin + Mineral Supplement With Folate, 1000 Iu Vitamin D, Immune Support Vitamins - Multivitamin With No Copper, No Iron (120 Capsules)

DESIGNS FOR HEALTH
CMF180
16.00 X 16.00 X 12.00 Inches
0.48 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

Full-Spectrum Multivitamin - This powerhouse multivitamin supplies supportive nutrients not normally found in regular multis, such as delta and gamma tocotrienols, TMG, and fruit bioflavanoids.

Premium Nutrients - Includes chelated minerals for maximum absorption as well as a full spectrum of vitamin K forms and levels of B vitamins based on our evolutionary intake of these nutrients.*

Iron & Copper Free - Appropriate for men and postmenopausal women.*

Always Pure & Effective Products - This product is Non-GMO and contains No Gluten, Dairy, or Soy. Eco-conscious, tinted glass bottles offer a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.*

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

#TOP5

Designs For Health Vitamin B Supreme - Vitamin B Complex For Mood + Energy Support - Bioactive Methyl Folate, Methyl B12, Niacinamide + Thiamine B1 Supplement (90 Vegan Capsules)

DESIGNS FOR HEALTH
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

Pre-Activated B Vitamins For Superior Absorption - This very powerful B complex vitamin supplement supplies most of the B vitamins in their coenzymated forms (including B12 methylcobalamin), meaning they are more readily available for the body to use than non-coenzymated forms.*

Premium B12 Folate Forms - Includes Quatrefolic folate, which has demonstrated high bioavailability, solubility, and long-lasting stability. This blend combines a premium folate and b12 supplement with all eight vitamins which form the B complex, including thiamine hcl, vitamin B5 pantothenic acid, and a biotin supplement.*

High Potency Energy Support Nutrients + Methylation Support - Trimethylglycine TMG and choline supplements can support methylation and thus the bioavailability of vitamin B nutrients. B complex vitamins can support mood, energy production, and cardiovascular health.*

Vegan & Non-GMO - B vitamins for women and men that are Vegetarian and Vegan-Friendly. Made without GMOs, Gluten, Dairy, or Soy. Tinted glass bottles offer a barrier against moisture and oxygen, which helps protect nutrient viability.*

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength vit b complex vitamins since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Twice Daily Multi - Iron-Free Adult Multivitamin Supplement - Multi Vitamin + Mineral For Adults With Vitamin C, B Vitamins, K, D, E, Folate + More - Non-Gmo (60 Capsules)

DESIGNS FOR HEALTH
TDM060
3.00 X 3.00 X 4.00 Inches
0.25 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

uperior Nutrient Forms - Uses higher quality ingredients than most multivitamins, including vitamin E Isomers as DeltaGold tocotrienols, a highly bioavailable form of folate, and true amino acid chelate minerals for optimal tolerance and absorption.*

With Active Folate - Contains 680 mcg of Quatrefolic methylfolate (5-MTHF), an innovative folate that has demonstrated high bioavailability and solubility as well as long lasting stability.*

Science-Based Nutrition - This exceptional balance of ingredients are combined in an up-to-date, science-based formulation to create a truly superior multi. Available in 60, 120, & 240 capsule bottles.*

Always Pure & Effective Products - This product is Non-GMO and Gluten-Free. DFH is transitioning to tinted glass bottles. Tinted glass offers a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.*

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Vitamin B Supreme - Vitamin B Complex For Mood + Energy Support - Bioactive Methyl Folate, Methyl B12, Niacinamide + Thiamine B1 Supplement (120 Vegan Capsules)

DESIGNS FOR HEALTH
BSP120
16.00 X 16.00 X 9.00 Inches
0.32 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

Pre-Activated B Vitamins For Superior Absorption - This very powerful B complex vitamin supplement supplies most of the B vitamins in their coenzymated forms (including B12 methylcobalamin), meaning they are more readily available for the body to use than non-coenzymated forms.*

Premium B12 Folate Forms - Includes Quatrefolic folate, which has demonstrated high bioavailability, solubility, and long-lasting stability. This blend combines a premium folate and b12 supplement with all eight vitamins which form the B complex, including thiamine hcl, vitamin B5 pantothenic acid, and a biotin supplement.*

High Potency Energy Support Nutrients + Methylation Support - Trimethylglycine TMG and choline supplements can support methylation and thus the bioavailability of vitamin B nutrients. B complex vitamins can support mood, energy production, and cardiovascular health.*

Vegan & Non-GMO - B vitamins for women and men that are Vegetarian and Vegan-Friendly. Made without GMOs, Gluten, Dairy, or Soy. Tinted glass bottles offer a barrier against moisture and oxygen, which helps protect nutrient viability.*

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength vit b complex vitamins since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Same Capsules With B6, B12 + 5-Mthf - 200Mg S-Adenosylmethionine Supplement With 5-Mthf (Folate) + Vitamin B12 - Non-Gmo + Gluten-Free (90 Capsules)

DESIGNS FOR HEALTH
4.00 X 3.00 X 5.33 Inches
0.65 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

Immune And Hormone Support - S-Adenosylmethionine or SAMe is a naturally occurring compound found in the human body as well as in plant and animal foods. It is involved in many processes throughout the body. SAMe plays a role in supporting the immune system and maintaining cell membranes, the protective barrier that surrounds all cells. It also helps to produce neurotransmitters like melatonin- that helps with your body's sleep cycle, and serotonin, the "feel good" hormone. *

Includes Necessary Cofactors - Each capsule provides 200 mg of SAMe along with vitamins B6, B12, and folate as 5-MTHF to provide cofactors for the natural conversions of SAMe to L-homocysteine and then safely to L-cysteine. *

Special Technology - Our SAMe capsules are made using special technology with a patented stabilized powder which protects the SAMe from being destroyed by air and moisture. This cutting-edge technology prevents its breakdown by stomach acidity and allows the capsule to be absorbed intact in the small intestine. *

Always Pure & Effective Products - This product is Vegetarian-Friendly, Non-GMO, and contains No Gluten, Dairy, or Soy. Eco-conscious, tinted glass bottles offer a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.*

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Adrenotone - Adrenal Support Supplement With Rhodiola Rosea, Ashwagandha, Vitamins B6, B2 + B5 - Designed To Support Adrenals + Healthy Cortisol Levels (90 Capsules)

DESIGNS FOR HEALTH
TP-0879452001442_VENDOR
12.00 X 12.00 X 9.00 Inches
0.19 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

Support Your Adrenals - Adrenotone is a combination of herbs and nutrients known to support the adrenals. This product is designed to help support already healthy cortisol levels, HPTA axis, and catecholamine production.*

Energy-Promoting Nutrients - This formula contains potent doses of vitamins B2, the active form of B6, Pantothenic Acid and Vitamin C. N-Acetyl L-Tyrosine offers amino acid support.*

Adaptogenic Herbs - Includes meaningful quantities of standardized herbal 'adaptogens' like Eleuthero, American Ginseng, Ashwagandha, and Rhodiola. These botanicals may promote a healthy response to stress.*

Always Pure & Effective Products - This product is Vegetarian-Friendly, Non-GMO, and contains No Gluten, Dairy, or Soy. DFH is transitioning to tinted glass bottles. Tinted glass bottles offer a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.*

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Catecholacalm - Adaptogenic Herbs + Vitamins For Mood, Calm + Adrenal Support With L-Theanine, Passion Flower + Phosphatidylserine - Non-Gmo Supplement (90 Capsules)

DESIGNS FOR HEALTH
TP-0879452001268_VENDOR
16.00 X 16.00 X 9.00 Inches
0.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

Support The Adrenals - This unique formulation addresses adrenal gland health. It is designed to support healthy catecholamine levels with adaptogenic herbs and nutrients.

Superior Nutrient Forms - The formula includes B vitamins such as the active forms of Methylcobalamin (B12) and P-5-P (B6). Vitamin C, Magnesium, Taurine, Phosphatidylserine (PS) and L-Theanine round out this focused nutrient profile.*

Herbal Support - Ashwagandha is an adaptogenic herb with a long history of use. Valerian, Lemon Balm and Passion Flower.

Higher Standards. Better Results - Designs for Health maintains a strict, no-compromises approach to quality raw material selection. We never cut corners with substandard ingredients. This product is Non-GMO, Gluten-Free, and Vegetarian-friendly.

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

#TOP11

Designs For Health Migranol - Feverfew Supplement With Magnesium Malate, Curcumin (Turmeric) Extract, Rosemary + B2 Riboflavin - Non-Gmo + Gluten Free (90 Capsules)

DESIGNS FOR HEALTH
TP-0879452001145_VENDOR
16.00 X 16.00 X 9.00 Inches
0.23 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

COMPREHENSIVE SUPPORT - Rosemary's active compound, carnosic acid, is especially supportive of the brain. Migranol also includes Magnesium and Riboflavin (Vitamin B2), a B vitamin required for the enzyme that helps recycle glutathione, the body's 'master antioxidant.'*

PROMOTE BLOOD FLOW - Feverfew has been studied extensively for its ability to support muscle relaxation throughout the body, including the delicate walls of blood vessels.*

SUPERIOR CURCUMIN COMPLEX - The curcumin in this product consists of the three strongest, most protective and best-researched curcuminoids: curcumin, bisdemethoxy curcumin, and demethoxy curcumin. This complex is standardized to 95% cucruminoids.*

HIGHER STANDARDS. BETTER RESULTS - Designs for Health maintains a strict, no-compromises approach to quality raw material selection. We never cut corners with substandard ingredients. This product is Non-GMO, Gluten-Free, and Vegetarian-friendly.

OVER 50,000 DOCTORS AGREE - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our ""Science First"" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Dfh Complete Multi With Copper + Iron - Comprehensive Multi Vitamin + Mineral Supplement With Folate, 1000 Iu Vitamin D, Immune Support Vitamins - Multivitamin (120 Capsules)

DESIGNS FOR HEALTH
CMU180
0.53 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

Full-Spectrum Multivitamin - This powerhouse multivitamin supplies supportive nutrients not normally found in regular multis, such as delta and gamma tocotrienols, TMG, and fruit bioflavanoids.

Premium Nutrients - Includes chelated minerals for maximum absorption as well as a full spectrum of vitamin K forms and levels of B vitamins based on our evolutionary intake of these nutrients.*

With Copper And Iron - Appropriate for teenagers, menstruating females, lactating women and individuals who avoid eating red meat.*

Always Pure & Effective Products - This product is Non-GMO and contains No Gluten, Dairy, or Soy. DFH is transitioning to tinted glass bottles. Eco-conscious, tinted glass bottles offer a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.*

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Dfh Complete Multi With Copper - Comprehensive Multi Vitamin + Mineral Supplement With Folate, 1000 Iu Vitamin D, Immune Support Vitamins - Multivitamin With No Iron (120 Capsules)

DESIGNS FOR HEALTH
16.00 X 16.00 X 12.00 Inches
0.50 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

Full-Spectrum Multivitamin - This powerhouse multivitamin supplies supportive nutrients not normally found in regular multis, such as delta and gamma tocotrienols, TMG, and fruit bioflavanoids.

Premium Nutrients - Includes chelated minerals for maximum absorption as well as a full spectrum of vitamin K forms and levels of B vitamins based on our evolutionary intake of these nutrients.*

Plus Copper, Minus Iron - This version contains 2 mg of copper as copper glycinate chelate, a stabilized mineral chelate that reduces the risk of free copper in the body, which can cause oxidative stress.*

Always Pure & Effective Products - This product is Non-GMO and contains No Gluten, Dairy, or Soy. DFH is transitioning to tinted glass bottles. Eco-conscious, tinted glass bottles offer a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.*

Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Designs For Health Vitamin D Supreme + B-Supreme Essentials Duo - 5000 Iu Vitamin D3 + Vitamin K, Active B Complex (2 Product Set)

DESIGNS FOR HEALTH
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Designs for Health 9.95

Features

TWO PREMIUM ESSENTIALS - Foundational vitamin duo featuring a high potency vitamin D supplement and B-Supreme, a powerful spectrum of B vitamins with TMG and choline.

5000 IU VITAMIN D3 + K - Vitamin D Supreme provides a high 5000 IU dose of vitamin D3, along with bioavailable vitamin K1 and K2 (MK-7). This formula provides the most absorbable, highly bioavailable form of vitamin K.

ACTIVATED B COMPLEX - Powerful B vitamin combination with most of the B vitamins in their coenzymated forms, promoting optimal bioavailability. Includes our proprietary NatureFolate blend of naturally-occurring folates, B12 as methylcobalamin, TMG and choline.*

NON-GMO + PREMIUM GLASS PACKAGING - Non-GMO with No Gluten, Dairy, or Soy. Packaged in more eco-conscious glass bottles. Tinted glass offers a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.*

OVER 50,000 DOCTORS AGREE - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our 'Science First' philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

Top 10 vitamin b supplements Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Designs For Health 14

Top 10 vitamin b supplements Brands Pie Chart


We've carried out a comprehensive analysis of 4,978 reviews on vitamin b supplements, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select vitamin b supplements priced around $54.47, with top brands including nature made, natures craft, nature's bounty, nurturly, honeycombs, vegepower, bronson, nordic naturals and methylpro and divine bounty

Our team of expert editors reviewed these high-quality items and handpicked the top 14 vitamin b supplements for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, natures craft deals, nurturly nutrition, honeycombs herbs & vitamins, beautyelan, bronson laboratories, nordic naturals, fortressbrand and divine bounty and gladness! .

We are dedicated to assisting our users in finding the right supplements Products based on their needs, saving them considerable time when choosing which vitamin b supplements to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.