Best Southern Weed Killers in 2026

Use with most pesticides to improve results

Don't let brown spots or mildew block your path to a beautiful yard; Scotts DiseaseEx Lawn Fungicide is a fast-acting formula that stops and prevents 26 common lawn-blemishing diseases

PREVENTS AND CONTROLS: This lawn fungus treatment is preventative when used on lawns to control brown spots and rings before they appear, and curative when applied on lawns showing signs of disease

CURES 26 LAWN DISEASE TYPES: Offers broad spectrum disease prevention and control against Brown Patch, Stem and Stripe Rust, Red Thread, Powdery Mildew, Necrotic Ring Spot, Summer Patch, Yellow Patch and more listed diseases

Scotts Turf Builder Weed & Feed5 weed killer plus fertilizer kills existing weeds and feeds to thicken your lawn and crowd out future weeds

Apply when weeds are actively growing and daytime temperatures are between 60°F and 90°F

Controls over 50 listed lawn weeds, including clover, dandelion, plantain, morningglory, chicory, eveningprimrose, and purslane

KILLS WEEDS AND GRASSES: use on driveways and walkways, and around fences, trees, flower beds, shrubs and other areas in your yard

KILLS THE ROOT: visible results as fast as 3 hours – replant new flowers, trees and shrubs the same weekend

RAINFAST: rainfall or watering 15 minutes after application will not wash away effectiveness

Visible results in hours - Reseed in just two weeks

Covers from 14,000 to 18,000 square feet - perfect for large property owners

Rapid and effective weed control for common and troublesome weed species in turfgrass

Product 1: Eliminates weeds at seedlings so new grass can flourish.

Product 1: Brand name: Syngenta

Product 1: Made in United States

Tenacity is a systemic pre-emergence and post-emergence herbicide for the selective contact and residual control of weeds in turfgrasses.

When applied as a pre-emergent, weeds absorb Tenacity during emergence from the soil.

Target pests: Barnyardgrass, Carpetweed, Chickweed, Clover, Crabgrass (large & smooth), Dandelion, Foxtail, Goosegrass, Henbit, Yellow Nutsedge, Purslane, Thistle, Wild Carrot and others

1 Application blocks weeds up to 6 months guaranteed

When used as directed Preen Extended Control Weed Preventer can be used around more than 600 perennials, groundcovers, shrubs and trees as listed on the product label

Flip-top applicator cap makes it easy to apply

Rainproof in 2 hours

Visible results in as little as 2 to 4 days. Single application kills most weeds

Contains 41-percent glyphosate

one application prevents crabgrass all season long

apply in spring to prevent crabgrass and problem weeds all season long

fall application prevents winter weeds, such as poa annua, henbit and chickweed

Convenient, ready-to-use refill is easy to pour right into your Roundup for Lawns Extended Wand bottle-no mixing required

Kills over 250 weeds, including crabgrass, dandelion, clover, and yellow nutsedge-won't harm your lawn

Lawn weed killer for use on Northern grasses, including Kentucky bluegrass, perennial ryegrass, fescue, bermudagrass, buffalograss, and zoysiagrass

Makes spraying liquid weed killers, insect killers, fungicides and fertilizers easier

Extended-grip design keeps hands dry during application

Direct-connect design makes attaching to Ortho concentrate bottles fast and easy

Kill weeds without harming your lawn (when used as directed) with Ortho WeedClear Lawn Weed Killer Ready-To-Use Refill; kills all major broadleaf weeds (see label for weed list), including dandelion, chickweed and crabgrass

RESULTS IN HOURS: This weed killer is rainproof in 1 hour and delivers visible results in hours, after just one application.

OVER 200 TYPES OF WEEDS: Kills weeds to the roots and won't harm the lawn when used as directed; kills over 200 types of weeds (see label for weed list)

SOUTHERN LAWNS: BioAdvanced Weed and Feed is specially formulated for Southern lawns

6-MONTH PROTECTION: Prevents broadlead, grassy weeds, and crabgrass for up to 6 months

WEED KILLER: Kills weeds including Dandelion, Dollarweed, and Clover

2-In-1 formula: kills existing lawn weeds and prevents listed weeds from emerging

6 Month protection: proprietary 2-in-1 formula kills and prevents weeds for up to 6 months

Weed killer: kills weeds including dandelion, dollar weed, and clover

Kills the toughest crabgrass and grassy weeds without harming lawns (when used as directed)

Designed for use on Northern lawns: Kentucky bluegrass, fine fescue, perennial ryegrass and tall fescue

Weeds will turn white 4-7 days after application. White means it's working!

All-in-one formula: BioAdvanced's all-in-one formula kills listed lawn weeds and crabgrass without harming the lawn

Weed killer: kills over 200 listed broadleaf weeds like dandelion and clover PLUS crabgrass

Root killer: kills even the toughest weeds to the root

✔️ PET & KID SAFE HERBICIDE - Eco Garden Pro Weed Killer is designed with you and your family in mind! All of our ingredients are carefully selected to be SAFE FOR: PETS, CHILDREN, BEES, FISH, AND ANY LIVESTOCK!

✔️ ORGANIC WEED KILLER - Formulated to KILL WEEDS AND GRASS FAST. Our proprietary formula will deliver IMMEDIATE RESULTS WITHIN 24 HOURS! Perfect for all residential, commercial, industrial, and agricultural use - including: driveways, sidewalks, concrete, mulch beds, pavement, flowers beds, parking lots, and farm lands.

✔️ WORKS within 24 HOURS POWERFUL PROPRIETARY FORMULATION - Our READY TO USE (RTU) formula contains natural white vinegar, organic rock salt, biodegradable plant activators, and fermentation derived co-factors, all designed to eliminate weeds and grass effectively and quickly.

CONTAINS NO GLYPHOSATE - Natural, Concentrated Formula For Making 250+ Types of Weeds and Grasses Stop Right in Their Tracks. Weeds and Grass Will Look Like You Took A Torch To Them.

EASY TO USE - People & Pet Friendly. Ready To Use, Just Spray and Go. No Messy Mixing or Diluting.

PLACES TO USE - Use Anywhere You Donâ€t Want Weeds and Grass Growing Such As, Around Flower Beds, Shrubs and Trees, Barns, Driveways, Edging, Fence Lines, Foundations, Gravel Areas, Mulch Beds, Overgrown Weed Areas, Parking Areas, Patios, Pavers, Pool Areas, Rock Walls and Pathways, Walkways, Wells & Water Systems. Any Location Where No Vegetation is Wanted

Kills Hard-To-Control Lawn Weeds

For Use On Cool-Season Grasses

Available In one gallon

Not your typical weed killer! Mesotrione prevents photosynthesis in plants. It will absorb and start working immediately, however, it can take up to 2-3 weeks before full death occurs on your weeds

Mesotrione must be activated by water. If rainfall hasn’t occurred within 10 days of application, water the area with 0.15 inches of water

Liquid Harvest Mesotrione targets 46 broadleaf species of weed and grass. It can combat Barnyard grass, Carpetweed, Chickweed, Clover, Crabgrass (large & smooth), Dandelion, Foxtail, Goosegrass, Henbit, Yellow Nutsedge, Purslane, Thistle, Wild Carrot, and others.

This selective weed killer kills or controls many Broadleaf Weeds and plants susceptible to 2, 4-D.

Works on Dandelion, Arrowhead, Buckhorn, Aster, Goatsbeard and more. See label for full list.

Pairs great with Hi-Yield Spreader Sticker (31063) for increased effectiveness.

Kills yellow and purple Nutsedge, Kyllinga and over 50 other tough weeds

For Northern and Southern turf grasses

Rainproof in 2 hours

Kills 470+ weed types as listed: this product kills broadleaf and grassy weeds, including dandelion, chickweed and clover as well as crabgrass and yellow nutsedge — see product label for complete list of weed types

Visible results IN 5 hours: the product kills by contact and kills weed roots, producing visible results in 5 hours

Kills listed weeds, not the lawn: Spectracide Weed Stop For Lawns plus crabgrass killer3 kills weeds including crabgrass — not the lawn, when used as directed

Scotts EZ Feed Plus Weed Control fertilizes lawns and kills broadleaf weeds all in one easy step

Weeds begin to curl up within a few days of an application (some hard-to-control weeds may require a repeat application in 3-to-4 weeks)

Controls carpetweed, clover, dandelion, goldenrod, ground ivy, poison ivy, ragweed, virginia creeper, wild onion, and other broadleaf weeds

Concentrate

Kills even the toughest weeds, like dandelion and clover

Specially formulated to control more than 200 weed types

Starts working on contact

ALL-in-ONE FORMULA: BioAdvanced's All-in-One formula kills listed lawn weeds and crabgrass without harming the lawn

WEED KILLER: Kills over 200 listed broadleaf weeds like dandelion and clover PLUS crabgrass

SMARTTRACK MARKER: SmartTrack non-staining red marker shows treated weeds and fades with sunlight

KILLS WEEDS TO THE ROOTS – Earth’s Ally is a non-selective, ready-to-use herbicide proven to eliminate common weeds like broadleaf, crabgrass, dandelion, clover, ivy and chickweed.

NO HARSH SYNTHETIC CHEMICALS – Earth’s Ally kills weeds with the power of sea salt. The pet safe weed killer contains safe ingredients that are an effective alternative to harsh synthetic chemicals.

VISIBLE RESULTS IN 3 HOURS - Spray weeds on a dry, sunny day and get visible results in 3 hours with our easy-to-use garden sprayer. About 4-5 sprays per weed will kill to the root on the first pass.

Long-Term Pond Weed Control: Provides an easy-to-use, all-season treatment for the entire water body. The systemic fluridone herbicide controls submerged and floating pond weeds slowly by reducing their chlorophyll, starving them of nutrients without a rapid oxygen depletion or a fish kill.

Combination Treatment Effective on Floating & Submerged Aquatic Weeds: Controls duck weed, water lilies, coontail, fanwort, watermilfoil, American pondweed, bladderwort, curly leaf pondweed, hydrilla, elodea, lily pads, sago pondweed, spatterdock, southern naiad, and other common species.

Easy Application: Simply mix treatment with pond water and pour in several spots around the pond's edge. Treat once and then enjoy your pond all season, without the hassle of continual treatments. A great solution for busy pond owners as well as for HOAs, commercial facilities, and golf courses with ponds. No sprayer or granular spreader required.