Best Vicks Cough Sore Throat Medicine in 2026

Daisy
Last Updated: Jul 20, 2026

At a Glance: Our Top Picks for Vicks Cough Sore Throat Medicine

ALKA-SELTZER PLUS Severe Cold - Sparkling Original Powerfast Fizz Effervescent Common Cold Tablets, Sinus Congestion, Runny Nose, and Dry Cough, 36CT
#TOP1
Alka-Seltzer Plus Severe Cold - Sparkling Original Powerfast
9.9
PM SCORE
ALKA-SELTZER PLUS Severe Night Cold PowerFast Fizz Effervescent Tablets, Lemon, 20 Count
#TOP2
Alka-Seltzer Plus Severe Night Cold Powerfast Fizz Effervescent
9.9
PM SCORE
ALKA-SELTZER PLUS Severe, Cold & Flu Medicine, Citrus Effervescent Tablets, Nasal & Sinus Congestion, Sneezing, Runny Nose, Cough, Sore Throat, Fever, Headache and Body Aches & Pains, 48ct
#TOP3
Alka-Seltzer Plus Severe, Cold & Flu Medicine, Citrus
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Vicks Cough Sore Throat Medicine of 2026

Alka-Seltzer Plus Severe Cold - Sparkling Original Powerfast Fizz Effervescent Common Cold Tablets, Sinus Congestion, Runny Nose, And Dry Cough, 36Ct

ALKA-SELTZER PLUS
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ALKA-SELTZER PLUS Severe Cold Sparkling Original POWERFAST Fizz EFFERVESCENT Cold Tablets provide fast relief from cold symptoms

Our severe cold, cough formula provides fizzy fast relief of: nasal congestion, sinus pressure & congestion, sneezing, runny nose, headache, fever, sore throat and body aches & pains.

Provides severe cold relief from congestion, coughing, and sore throat

Each box containing 18 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes this cold remedy easy to take with you on the go.

Works as flu and cold relief with acetaminophen as an ingredient

Alka-Seltzer Plus Severe Night Cold Powerfast Fizz Effervescent Tablets, Lemon, 20 Count

ALKA-SELTZER PLUS
016500587590-VC
2.68 X 1.93 X 3.19 Inches
0.18 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Spintrex 7.81

Features

Our fantastic formula made even better: improved flavor, less sodium, & aspartame free

Our severe Cold night formula provides unbeatably liquid fast relief of headache, sore throat, cough, nasal congestion, sinus pressure & Congestion, runny nose, sneezing, Aches & pains and fever.

Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.

Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go

Comes in Effervescent form, with a refreshing lemon flavor. Use as directed.

Alka-Seltzer Plus Severe, Cold & Flu Medicine, Citrus Effervescent Tablets, Nasal & Sinus Congestion, Sneezing, Runny Nose, Cough, Sore Throat, Fever, Headache And Body Aches & Pains, 48Ct

ALKA-SELTZER PLUS
3.86 X 3.23 X 4.33 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Our fantastic formula made even better: improved flavor, less sodium, & aspartame free

Our severe Cold & Flu medicine formula provides unbeatably fast relief of headache, sore throat, cough, nasal & sinus congestion, runny nose, sneezing, aches & pains and fever.

#1 Cold & Flu effervescent Brand

Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.

Each box containing 24 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go

Alka-Seltzer Plus Severe Non-Drowsy Cold & Flu Powerfast Fizz Citrus Effervescent Tablets 20 Count (Pack Of 1)

ALKA-SELTZER PLUS
1692945
2.68 X 1.93 X 3.19 Inches
0.17 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Our fantastic formula made even better: Improved flavor, less sodium and aspartame free

Our severe Cold and Flu formula provides unbeatably liquid fast relief of headache, sore throat, cough, nasal and sinus congestion, runny nose, sneezing, Aches, pains and fever.

Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.

Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go

Comes in Effervescent form, in a refreshing citrus flavor. Use as directed.

Alka Seltzer Plus Severe Non-Drowsy Cold & Cough Powerfast Fizz Effervescent Common Cold Tablets, Sinus Congestion, Runny Nose, And Dry Cough, Citrus Flavor, 20 Count (Pack Of 1)

ALKA-SELTZER PLUS
016500587620-VC
2.68 X 1.93 X 3.19 Inches
0.17 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
MASKU LLC 9.65

Features

ALKA-SELTZER PLUS Severe Non-Drowsy Cold & Cough PowerFast Fizz Effervescent Tablets is a cold remedy for adults, with less sodium, improved flavor, and aspartame free.

Our severe Cold & Cough formula provides unbeatably liquid fast cold relief of headache, sore throat, cough, nasal & sinus congestion, runny nose, sneezing, aches, pains, fever and other severe cold symptoms.

Also acting as a cough suppressor and dry cough medicine, the non-drowsy formula allows individuals to stay alert and productive while battling cold symptoms.

Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes this cold remedy for adults easy to take with you on the go

The cold tablets are designed to dissolve quickly in water, creating a refreshing and effervescent citrus-flavored drink while tackling your severe cold & cough symptoms.

Alka-Seltzer Plus Severe,Cold & Cough Medicine For Adults,Powerfast Fizz Citrus Effervescent Tablets,Fast Relief Of Headache,Sore Throat,Cough,Nasal & Sinus Congestion,Runny Nose,& Fever,48Ct

ALKA-SELTZER PLUS
3.86 X 3.23 X 4.33 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Our fantastic formula made even better: improved flavor, less sodium, and aspartame free

Our severe Cold and Cough medicine formula provides unbeatably liquid fast relief of headache, sore throat, cough, nasal and sinus congestion, runny nose, sneezing, aches and pains and fever

Quickly dissolves in water and instantly ready to start working so you can get back to your busy life

Cold and Flu Effervescent Brand

Each box containing 24 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go

Alka-Seltzer Plus Non-Drowsy Cold Powerfast Fizz Effervescent Tablets For Adults With Nasal & Sinus Congestion/Cough/Sore Throat/Fever/Headache And Body Aches & Pains, Citrus, 20 Count (Pack Of 1)

ALKA-SELTZER PLUS
016500590965-VC
2.68 X 1.93 X 3.19 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Bigfoot Distribution 9.42

Features

Our fantastic formula made even better: improved flavor, less sodium, & aspartame free

Our severe non-drowsy formula provides unbeatably liquid fast relief of sore throat, cough, nasal & sinus congestion, headache, Aches & pains and fever.

Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.

Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go

Comes in Effervescent form, with a refreshing citrus flavor. Use as directed.

Alka-Seltzer Plus Severe Cold & Flu Day/Night Medicine For Adults And Children 12 Years And Older - Powerfast Fizz Effervescent Tablets For Common Cold Relief And Other Cold Symptoms, 48Ct

ALKA-SELTZER PLUS
3.86 X 3.23 X 4.33 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

ALKA-SELTZER PLUS Severe Cold Day Night Medicine is a powerful cold and flu medicine designed specifically for adults and children 12 years and older.

Our Severe Day and Night cold and flu medicine provides fizzy fast daytime relief of nasal & sinus congestion, cough, headache, fever, sore throat and body aches & pains. Provides nighttime cold relief of: nasal congestion, sinus pressure & congestion, sneezing, runny nose, cough, headache, fever, sore throat and body aches & pains.

This cold and flu medicine for adults and children 12 years and older quickly dissolves in water and instantly ready to start working so you can get back to your busy life

Each flu & cold relief box has 24 Sachets each containing 1 individually wrapped dose (2 effervescent cold tablets), which makes it easy to take with you on the go

Each cold and flu medicine tablet comes in Effervescent form. Use as directed.

Packaging may vary

Top 10 cough sore throat medicine Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Alka-Seltzer Plus 8

Top 10 cough sore throat medicine Brands Pie Chart


We've carried out a comprehensive analysis of 12,724 reviews on cough sore throat medicine, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select cough sore throat medicine priced around $15.92, with top brands including mucinex, boiron, chloraseptic, vicks, theraflu, alka-seltzer plus, robitussin, hyland's and sucrets and ricola

Our team of expert editors reviewed these high-quality items and handpicked the top 8 cough sore throat medicine for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, nc commercial, greatprices4u, bnt distributor, incredible designs llc, name brand overstock, healthy products a plus llc, the customer land and beekeeper's naturals and focus health .

We are dedicated to assisting our users in finding the right medicine Products based on their needs, saving them considerable time when choosing which cough sore throat medicine to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.