Best Refresh Eye Drops For Dry Eyes in 2026

Daisy
Last Updated: Aug 2, 2026

At a Glance: Our Top Picks for Refresh Eye Drops For Dry Eyes

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each
#TOP1
Systane Ultra Lubricant Eye Drops, Artificial Tears For
10.0
PM SCORE
Refresh Tears Lubricant Eye Drops (0.5 Fl Oz - 2 Count) & Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count - 60 Day Supply)
#TOP2
Refresh Tears Lubricant Eye Drops (0.5 Fl Oz
9.9
PM SCORE
LUMIFY Redness Reliever Eye Drops 0.25 Ounce (7.5mL)
#TOP3
Lumify Redness Reliever Eye Drops 0.25 Ounce (7.5Ml)
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Refresh Eye Drops For Dry Eyes of 2026

Market Overview
Refresh Eye Drops For Dry Eyes Reviewed
  • Reviews Analyzed: 465194 Items
  • PM Avg. Rating: 8.8 / 10
91 Products Evaluated
  • Highest Price: $109.80
  • Lowest Price: $2.99
  • Avg. Price: $19.75

Systane Ultra Lubricant Eye Drops, Artificial Tears For Dry Eye, Twin Pack, 10-Ml Each

SYSTANE
65143141
6.00 X 5.00 X 4.00 Inches
0.05 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

#1 Dr Recommended Brand of Artificial Tears*, packaging may vary

Extended Protection

Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature

Reduces both the signs and symptoms of dry eye

Quickly soothe irritated eyes wherever you are

Refresh Tears Lubricant Eye Drops (0.5 Fl Oz - 2 Count) & Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count - 60 Day Supply)

REFRESH
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Contains Refresh Tears Lubricant Eye Drops, 0.5 Fl Oz (2 Count) and Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count) 60 Day Supply

Original strength formula; Relieves mild symptoms of eye dryness

FAST-ACTING EYE ITCH RELIEF: Relieves itchy eyes from allergies in as little as 3 minutes

Lumify Redness Reliever Eye Drops 0.25 Ounce (7.5Ml)

LUMIFY
2.38 X 1.38 X 3.81 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Eye Drops for Red Eyes: LUMIFY significantly reduces redness to help reveal your eyes' natural radiance. From the eye care experts at Bausch and Lomb, LUMIFY works in 1 minute and lasts up to 8 hours

LUMIFY is different: The only OTC drop to contain brimonidine. It selectively targets redness, alleviating some potential side effects associated with other redness relief drops, when used as directed

LUMIFY contains no bleach or dyes. It’s Doctor recommended redness reliever (data on file)

Eye Care Experts at Bausch and Lomb: For over 150 years, we have focused on innovation and quality in eye care products, from contact lenses and solutions to eye drops, ointments, eye vitamins, and more

Amazing Looking Eyes: We understand how important eyes are. And despite all the eye creams, mascara, eyeliners and eyeshadows, if your eyes are red, you won’t look your best

Refresh Optive Mega-3 Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count

REFRESH
4.00 X 3.00 X 4.75 Inches
0.24 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Preservative-free moisture-rich formula; On-the-go single use vials

Designed to relieve eye dryness that may be due to Meibomian Gland Dysfunction.

Delivers advanced hydration and lubrication

Supports all three tear film layers

Helps prevent tears from evaporating

The only eye drop in the U.S. with Carboxymethylcellulose Sodium, Glycerin, and Flaxseed Oil (an inactive ingredient)

Hydrocell technology enables hydration and maintains the volume of cells on the ocular surface

The brand in preservative-free artificial tears; IRI Artificial tears preservative-free dollar and unit sales by manufacturer.

#TOP5

Systane Complete Lubricant Eye Drops, 10 Ml

SYSTANE
211281
1.25 X 1.75 X 3.88 inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
DeRomo 9.92

Features

Optimal dry eye relief

Nano-droplet technology takes our coverage to another level

Soothes eyes with fast-acting hydration

Hydrates fast and provides long-lasting relief.

#1 Doctor Recommended Brand for Artifical Tears

Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary

REFRESH
5783
5.00 X 5.00 X 5.00 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Original strength, preservative-free formula

Relieves mild symptoms of eye dryness

Instantly moisturizes and lubricates

Designed to act like your own natural tears

Great for sensitive eyes

Value size: 50 on-the go, single-use vials

Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.

The brand in preservative-free artificial tears; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Clear Eyes Redness Eye Relief Eye Drops, Relieves Redness & Calms Irritation, 0.2 Fl Oz

CLEAR EYES
361953
0.63 X 3.00 X 5.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Clear Eyes handy pocket Pal redness relief eye drops relieve redness from minor irritations and protect against further irritations

Soothes and moisturizes to relieve redness

Helps irritation, burning, and mild dry eyes

Same formulation in a convenient travel size

From the #1 brand of eye drops; provides up to 12 hours of soothing comfort

Allergy Eye Drops By Bausch & Lomb, For Itch & Redness Relief, 15 Ml (Pack Of 2), Packaging May Vary

OPCON-A
AB55299
2.60 X 1.10 X 3.40 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ALLERGY EYE DROPS: Opcon-A eye drops combine an antihistamine with redness reliever to help relieve itchy, red, irritated eyes. Temporarily relieves itching & redness caused by pollen, ragweed, grass, animal hair & dander

RELIEF FOR ITCHY EYES: Opcon-A eye drops are clinically proven to help temporarily relieve the redness & itching caused by symptoms of common airborne allergens like ragweed or grass

BAUSCH and LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops

EYE CARE EXPERTS: For over 150 years, Bausch and Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more

EYE DROPS & MORE: Bausch and Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to make sure your eyes feel healthy, moisturized & protected

Visine Red Eye Hydrating Comfort Redness Relief And Lubricant Eye Drops To Help Moisturize And Relieve Red Eyes Due To Minor Eye Irritations Fast, Tetrahydrozoline Hcl, 0.5 Fl. Oz

VISINE
MDB4901
1.07 X 1.76 X 3.75 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

0.5-fluid ounce bottle of Visine Red Eye Hydrating Comfort Redness Relief Eye Drops to offer eye redness relief in 30 seconds and lubricate irritated eyes

Formula contains 1% polyethylene glycol 400 and 0.05% tetrahydrozoline HCl which helps lubricate, refresh and relieve red irritated eyes

Fast-acting redness relief & moisturizing formula relieves symptoms due to minor eye irritations like exposure to smoke, lack of sleep and extended screen time and comes from Visine, a brand backed by 60 years of expertise

The sterile eye drops help hydrate to soothe eye irritation & provide redness relief

The small bottle is conveniently-sized and can be easily carried in your pocket, purse or bag for on-the-go relief anywhere

Genteal Tears Lubricant Eye Drops, Moderate Liquid Drops, Twin Pack ,0.5 Fl Oz (Pack Of 2) Package May Vary

GENTEAL
0065042637
1.25 X 2.56 X 4.25 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Moderate Dry Eye Symptom Relief

Fast Soothing Relief

Quick relief from moderate irritation and discomfort

Relieves discomfort: Provides relief from moderate irritation and discomfort caused by dry eye symptoms

Allergan Refresh Plus Lubricant Eye Drops Single-Use Vials, Clear, (100 Count (Pack Of 1))

REFRESH
B0799BHPS3
4.00 X 3.20 X 6.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Carnie Universal 9.84

Features

Long-lasting relief plus protection

No preservatives

#1 Doctor recommended

100 Vials

For mild to moderate dry eye including lasik dryness

Systane Long Lasting Lubricant Eye Drops Vials Eye Drops, 30 Count (Pack Of 1)

SYSTANE
531529
1.38 X 2.95 X 4.65 Inches
0.15 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Dr Recommended Brand of Artificial Tears

Reduces both the signs and symptoms of dry eye

Long Lasting Relief

Soothing comfort; Dry Eye Therapy

Single-Use Convenience

Boiron Optique1 Preservative Free Eye Drops For Relief From Eye Irritation, Dry Eyes, Allergies, Eyestrain, & Red Itchy Eyes, Single-Unit Doses - 30 Count

BOIRON
306969277720
2.13 X 3.50 X 4.25 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Temporarily relieves minor eye irritation due to fatigue or airborne irritants

Soothes red, dry, itchy, gritty, burning or tired eyes

Preservative-free; No vasoconstrictors or astringents

For everyone ages 2 & up

Also available in a box of 10 sterile, single-use liquid oral doses

Visine Dry Eye Relief Lubricant Eye Drops To Moisturize And Soothe Irritated, Gritty And Dry Eyes, Designed To Work Like Real Tears, Polyethylene Glycol 400, Twin Pack, 2 X 0.5 Fl. Oz

VISINE
524936200
1.84 X 2.20 X 3.80 Inches
3.55 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Twin pack containing two 0.5-fluid ounce bottles of Visine Dry Eye Relief Lubricant Dry Eye Drops to provide dry eye relief and protection from further eye irritation

These sterile moisturizing eye drops provide soothing relief of dry, gritty and irritated eyes and are designed to work like real tears

The hydrating drops lubricate eyes, feature polyethylene glycol 400 and contain 10 ingredients found in your own natural tears

Helps relieve dry eye symptoms such as burning and irritation due to activities such as extended screen use while also helping to protect against further eye irritation.

Visine Dry Eye Relief Lubricant Eye Drops are available in a small, convenient-to-carry bottle for convenient relief anywhere, even on-the-go

Refresh Relieva Lubricant Eye Drops, 0.33 Fl Oz Sterile, Packaging May Vary

REFRESH
1.13 X 1.75 X 3.50 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Innovative formula relieves discomfort due to dry, irritated eyes

Prevents further irritation

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

Also available in a preservative-free formula and a formula for contact lens wearers. Store at 59-86F 15-30C

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Systane Hydration Preservative-Free Lubricant Eye Drops, Transparent, 0.6 Fl Oz, 30 Count

ALCON
0065143704
2.95 X 1.38 X 4.65 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Healthi Solutions 9.85

Features

Hydrates fast and provides long-lasting relief.

#1 Doctor & pharmacist Recommended brand

Preservative free

Contains hyaluronate for advanced hydration

Safe for use with all contact lenses

Systane Balance Lubricant Eye Drops, Restorative Formula, Twin Pack, 0.33 Fl Oz (Pack Of 2)

SYSTANE
B010CQVOEM
1.28 X 2.59 X 4.31 Inches
0.09 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Consensus Holdings 9.88

Features

Clinical strength intensive therapy

Restorative formula

Upgrade to a higher standard of relief

Uses : For the temporary relief of burning and irritation due to dryness of the eye. Direction for Use : Shake well before using. Instill 1 or 2 drops in the affected eye(s) as needed.

Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile

REFRESH
92056
3.60 X 1.90 X 1.00 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Original strength gel formula

Relieves dry, burning, irritated eyes

Alleviates discomfort

Keeps eyes feeling better longer

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun

Oasis Tears Plus Lubricant Eye Drops Relief For Dry Eyes, 30 Count Box Sterile Disposable Containers (Pack Of 3)

OASIS
OT6200-03
6.00 X 3.00 X 3.50 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
VerSure 9.98

Features

Recommended for the relief of moderate to severe dry eye symptoms

For day or night time use

Preservative-free

Refresh Celluvisc Lubricant Eye Gel Drops, Single-Use Containers, 30 Count (Pack Of 1)

REFRESH
178053
4.06 X 3.00 X 2.01 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Original strength gel formula

Relieves dry, burning, irritated eyes

Alleviates discomfort

Keeps eyes feeling better longer

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Genteal Tears Gel Drops, 8 Ml

GENTEAL
0065806701
1.75 X 1.25 X 3.88 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Product Type:Medication

Item Package Dimension:1.75 " L X1.25 " W X3.88 " H X

Item Package Quantity:1

Country Of Origin: United States

#TOP22
Best For Box

Eye Drops By Bausch & Lomb, Lubricant Relief For Dry Eyes, Preservative Free, Single Use Dispensers, 0.6 Ml, 28 Count (Pack Of 2)

SOOTHE
622219_OB
4.20 X 3.20 X 4.70 Inches
0.15 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
VerSure 9.98

Features

LONG LASTING, FAST RELIEF DRY EYE THERAPY: Use Soothe Lubricant Eye Drops to help moisturize & refresh dry eyes for long-lasting relief & comfort Formulated to relieve dryness of the eye & help prevent irritation

DRY EYE DROPS: Tear replacement drops are important to help relieve dry eye symptoms. Inactive Ingredients are boric acid, hydroxyalkylphosphonate, purified water, sodium alginate, sodium borate

BAUSCH + LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops

EYE CARE EXPERTS: For over 150 years, Bausch + Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more

EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to make sure your eyes feel healthy, moisturized, & protected

Rohto Dryaid Eye Relief Lubricant Eye Drops, Twin Pack, Dry Eye Relief, 0.34 Fl Oz

ROHTO
9843
2.59 X 1.28 X 4.31 Inches
0.08 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Two 0.34 fl oz bottles of Rohto Dry-Aid Eye Relief Lubricant Eye Drops

Provides fast-acting, non-blurring dry eye relief and superior comfort; Dry eye treatment with Liquidshield (TM) technology to mimic real tears and restore moisture

Relieves dryness due to electronics use, hormonal issues, environmental factors, and other irritation; Compact, portable bottle for convenient use

Apply one to two drops for up to 12 hours of relief

From the #1 global OTC eye care brand

Systane Lubricant Eye Gel Drops, 10-Ml (Packaging May Vary)

SYSTANE
ALCON528448
1.25 X 1.76 X 3.86 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

#1 Dr Recommended Brand of Artificial Tears*

Thicker eye drop formulation that creates a protective shield over your eyes.

Convenience of a drop with a protection of a gel.

For the temporary relief of burning and irritation due to dryness of the eye

NOTE: PRODUCT PACKAGING MAY VARY

Bausch + Lomb Soothe Preservative-Free Lubricant Eye Drops, Xtra Protection, Box Of 30 Single Use Dispensers

SOOTHE
11-IPLQ-8OZF
2.95 X 2.17 X 4.72 Inches
0.15 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

EXTRA PROTECTION FOR DRY EYES: Soothe XP Preservative Free Eye Drops do what ordinary eye drops (non-lipid containing) can't This formula helps restore the eyes lipid layer for relief that lasts, but is preservative free for sensitive eyes

DIFFERENT THAN ARTIFICIAL TEARS: MGD, which often includes breakdown of the lipid layer, is the main cause of evaporative dry eye Soothe XP Dry Eye Drops help restore the lipid layer to seal in moisture & protect against further irritation

BAUSCH and LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops

EYE CARE EXPERTS: For over 150 years, Bausch and Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more

EYE DROPS & MORE: Bausch and Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to make sure your eyes feel healthy, moisturized, & protected

Systane Complete Pf Multi-Dose Preservative Free Dry Eye Drops 10Ml

SYSTANE
AL150928
2.00 X 2.00 X 2.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Fast acting hydration for sensitive eyes

Preservative free tear evaporation protection

Nano droplets for better coverage

Refresh P.m. Lubricant Eye Ointment, Nighttime Relief, Preservative-Free, 0.12 Oz Sterile, Packaging May Vary

REFRESH
95761
2.80 X 0.90 X 3.30 inches
0.01 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Nighttime relief for intense eye dryness

Preservative-free

Soothes eyes while you sleep

Protects eyes from nighttime dryness due to exposure

Ideal for use at bedtime

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Eye Ointment By Bausch & Lomb, Lubricant Relief For Dry Eyes, 3.5 G

SOOTHE
AB31336
0.01 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Vitabox 9.88

Features

Soothing nighttime dry eye relief

Contains no preservatives

Gentle enough to use as often as needed

Remove contact lenses before using

Oasis Tears Pf Preservative-Free Lubricant Eye Drops Relief For Dry Eyes, 0.34 Ounce

OASIS
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Healthy Eyes 9.88

Features

Oasis TEARS PF Preservative-Free Lubricant Eye Drops Relief For Dry Eyes, 0.34

Refresh Classic Lubricant Eye Drops, Preservative-Free,0.01 Fl Oz Single-Use Containers, 50 Count (Pack Of 1), Packaging May Vary

REFRESH
4889
6.00 X 4.00 X 4.00 Inches
0.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Relieves mild symptoms of eye dryness

Instantly moisturizes and lubricates

Designed to act like your own natural tears

Preservative-free formula

Great for sensitive eyes

Value size! 50 on-the go, single-use vials

The #1 selling brand in preservative-free artificial tears.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Top 10 eye drops for dry eyes Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Refresh 20
Systane 16
Soothe 5
Visine 5
Clear Eyes 4
Genteal 4
Biotrue 3
Dr Vitamin Solutions 3
Boiron 2
Oasis 2

Top 10 eye drops for dry eyes Brands Pie Chart


We've carried out a comprehensive analysis of 465,194 reviews on eye drops for dry eyes, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select eye drops for dry eyes priced around $19.75, with top brands including theratears, systane, refresh, ocusoft, ivizia, similasan, visine, clear eyes and octiq and lumify

Our team of expert editors reviewed these high-quality items and handpicked the top 30 eye drops for dry eyes for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, healthi solutions, evergreencreations, buy wise from us, aytu consumer health, barginhousedeals, consensus holdings, carnie universal and jjbookit and healthy eyes .

We are dedicated to assisting our users in finding the right drops Products based on their needs, saving them considerable time when choosing which eye drops for dry eyes to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.