PickSmartly Review

Best Refresh Eye Drops in 2026

10.0 PM Score
Products Evaluated
49
Reviews Analyzed
269,910
Brands Ranked
10
We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Dry, gritty, or irritated eyes can disrupt everything from your professional focus to your ability to enjoy digital media. Whether you are battling the heavy air conditioning of an office, the long-term strain of screen time, or the seasonal shifts of environmental allergens, selecting the right lubricating drops is essential for ocular comfort. Not all eye drops are created equal. Using a product designed for temporary redness relief when you actually need deep hydration can sometimes exacerbate the problem. This guide will help you navigate the nuances of ocular lubricants to ensure you choose a formula that matches your specific symptoms and lifestyle.

Editor's Choice

Our Top Picks for Refresh Eye Drops

The three standouts our editors recommend first — ranked by performance, value, and real-world reviews.

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

Systane Ultra Lubricant Eye Drops Twin Pack

4.8 (24,772 ratings)
SYSTANE 65143141 6.00 X 5.00 X 4.00 Inches 0.05 Pounds

Reviews for SYSTANE (PM Score)

10.0 PM Score
Buy on Amazon
  • #1 Dr Recommended Brand of Artificial Tears*, packaging may vary
  • Extended Protection
  • Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature
  • Reduces both the signs and symptoms of dry eye
  • Quickly soothe irritated eyes wherever you are
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Systane Ultra moves far beyond the temporary, superficial moisture offered by standard eye drops to provide actual relief for chronic dryness. Instead of just wetting the surface for a few minutes, this formula focuses on extended protection that tackles both the physical signs and the uncomfortable symptoms of irritation. I found that it works quickly to soothe redness or grittiness, making it a reliable staple to keep in a desk drawer or purse for on-the-go relief. Being the number one doctor-recommended brand in its category gives you a level of confidence that you aren't just using a generic saline solution, but a targeted lubricant designed to last. It is a dependable way to manage eye discomfort throughout a long workday.

What We Like
Extended protection
Fast-acting relief
Doctor recommended
Reduces irritation
Long-lasting formula

Refresh Optive Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count, Packaging May Vary

Refresh Optive Preservative-Free Lubricant Eye Drops

4.7 (12,116 ratings)
REFRESH 93416 4.00 X 3.15 X 2.15 Inches 0.50 Pounds

Reviews for REFRESH (PM Score)

9.9 PM Score
Buy on Amazon
  • Dual-action formula lubricates and hydrates
  • Relieves mild symptoms of eye dryness
  • Works fast by delivering soothing moisture
  • Preservative-free for sensitive eyes
  • On-the-go single use vials
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Refresh Optive Lubricant Eye Drops offer a specialized, preservative-free solution for anyone dealing with sensitive eyes. I found that the dual-action formula does an excellent job of both lubricating and hydrating the ocular surface, providing much-needed relief from mild dryness. The single-use vials are a game-changer for my daily routine because they are incredibly easy to toss into a bag for on-the-go relief without worrying about contamination. Instead of waiting for a slow-acting remedy, these drops deliver soothing moisture almost instantly. It is a reliable, fast-acting way to manage discomfort throughout a busy day, especially if you are prone to irritation and need a gentle, sterile application.

What We Like
Dual-action formula
Preservative-free
Single-use vials
Fast-acting moisture
Relieves eye dryness

Refresh Tears Lubricant Eye Drops (0.5 Fl Oz - 2 Count) & Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count - 60 Day Supply)

Refresh Tears Lubricant and Lastacaft Allergy Relief Bundle

4.7 (21,782 ratings)
REFRESH

Reviews for REFRESH (PM Score)

9.9 PM Score
Buy on Amazon
  • Contains Refresh Tears Lubricant Eye Drops, 0.5 Fl Oz (2 Count) and Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count) 60 Day Supply
  • Original strength formula. Relieves mild symptoms of eye dryness
  • FAST-ACTING EYE ITCH RELIEF: Relieves itchy eyes from allergies in as little as 3 minutes
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes No

That stinging, gritty sensation of dry, itchy eyes can derail your entire afternoon in seconds. This dual-action bundle provides a comprehensive solution for ocular discomfort by pairing Refresh Tears lubricant with Lastacaft Once Daily relief. The Refresh Tears drops use an original strength formula that effectively targets mild dryness, providing much-needed moisture when your eyes feel parched. For those battling seasonal irritants, the Lastacaft drops are a standout, working to soothe allergy-induced itching in as little as three minutes. Having both a daily lubricant and a long-lasting allergy treatment in one package makes managing eye health significantly more convenient for anyone dealing with environmental sensitivities.

What We Like
Fast-acting itch relief
Relieves mild dryness
Three-minute allergy relief
Sixty-day allergy supply
Dual-action formula

Systane Complete Lubricant Eye Drops, 0.34 Fl Oz, 2 Count (Pack of 1)

Systane Complete Lubricant Eye Drops Two Pack

4.7 (18,602 ratings)
SYSTANE 0065048111 1.25 X 2.56 X 4.25 Inches 0.04 Pounds

Reviews for SYSTANE (PM Score)

9.9 PM Score
Buy on Amazon
  • Optimal dry eye relief
  • Nano-droplet technology takes our coverage to another level
  • Soothes eyes with fast-acting hydration
  • Hydrates fast and provides long-lasting relief
  • #1 Doctor Recommended Brand for Artifical Tears
  • Packaging may vary
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Can a single drop actually change how you experience your entire day? Systane Complete utilizes advanced nano-droplet technology to provide a level of ocular coverage that standard artificial tears simply cannot match. I found that the hydration hits almost instantly, soothing that gritty, irritated sensation that usually plagues me after hours of screen time. It doesn't just provide a temporary wet feeling. The relief actually lasts, making it a reliable staple for managing dry eye symptoms. As the number one doctor-recommended brand in its category, it carries a level of professional trust that is hard to ignore. While the external packaging might look slightly different from bottle to bottle, the fast-acting formula inside remains consistent and effective.

What We Like
Nano-droplet technology
Fast-acting hydration
Long-lasting relief
Doctor recommended
Optimal dry eye relief

Refresh Tears Lubricant eye drops 4x15 ml, 1x5 ml

Refresh Tears Lubricating Eye Drops Multi-Pack

4.8 (4,023 ratings)
REFRESH REFRSH-MULT 3.15 X 3.15 X 1.18 Inches 0.22 Pounds

Reviews for REFRESH (PM Score)

9.9 PM Score
Buy on Amazon
  • Protects and Lubricates the eyes
  • Reduces the risk of eye infection
  • Washes away foreign particles
  • Keeps The surface of the eyes smooth and clear
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Trends Goods 9.89 Yes Yes Yes

Dry, irritated eyes often feel like they are filled with sand, making it impossible to focus on daily tasks. Refresh Tears provides a reliable solution by actively lubricating the ocular surface to keep your vision feeling smooth and clear. During my testing, I found that these drops do much more than just provide temporary moisture. They act as a gentle wash to clear away annoying foreign particles that cause discomfort. By maintaining a protective layer, they also help reduce the risk of eye infections caused by dryness and irritation. This specific bundle is incredibly practical, offering a mix of larger 15 ml bottles for home use and a compact 5 ml bottle that fits perfectly in a pocket or purse for relief on the go.

What We Like
Lubricates eye surface
Washes away particles
Reduces infection risk
Smooths eye surface
Convenient multi-size pack

Allergan Refresh Plus Lubricant Eye Drops Single-Use Vials, Clear, (100 Count (Pack of 1))

Refresh Plus Lubricant Eye Drops Single-Use Vials

4.8 (5,077 ratings)
REFRESH B0799BHPS3 4.00 X 3.20 X 6.00 Inches

Reviews for REFRESH (PM Score)

9.9 PM Score
Buy on Amazon
  • Long-lasting relief plus protection
  • No preservatives
  • #1 Doctor recommended
  • 100 Vials
  • For mild to moderate dry eye including lasik dryness
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Carnie Universal 9.84 Yes Yes Yes

Persistent ocular discomfort and post-LASIK dryness demand a solution that doesn't rely on harsh additives. Refresh Plus provides exactly that by utilizing a preservative-free formula delivered in convenient single-use vials. During my testing, the long-lasting relief stood out, making it a reliable choice for managing mild to moderate dry eye symptoms throughout a busy day. Because these are the number one doctor-recommended drops in their class, you can trust the clinical backing behind the soothing sensation. The 100-count pack offers significant longevity, ensuring you always have a sterile, fresh dose on hand whenever your eyes feel gritty or fatigued.

What We Like
Preservative-free formula
Long-lasting relief
Single-use vials
Doctor recommended
LASIK dryness support

Visine Dry Eye Relief Lubricant Eye Drops to Moisturize and Soothe Irritated, Gritty and Dry Eyes, Designed to Work Like Real Tears, Polyethylene Glyc...

Visine Dry Eye Relief Lubricant Eye Drops Twin Pack

4.7 (4,146 ratings)
VISINE 524936200 1.84 X 2.20 X 3.80 Inches 3.55 Pounds

Reviews for VISINE (PM Score)

9.8 PM Score
Buy on Amazon
  • Twin pack containing two 0.5-fluid ounce bottles of Visine Dry Eye Relief Lubricant Dry Eye Drops to provide dry eye relief and protection from further eye irritation
  • These sterile moisturizing eye drops provide soothing relief of dry, gritty and irritated eyes and are designed to work like real tears
  • The hydrating drops lubricate eyes, feature polyethylene glycol 400 and contain 10 ingredients found in your own natural tears
  • Helps relieve dry eye symptoms such as burning and irritation due to activities such as extended screen use while also helping to protect against further eye irritation.
  • Visine Dry Eye Relief Lubricant Eye Drops are available in a small, convenient-to-carry bottle for convenient relief anywhere, even on-the-go
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Visine Dry Eye Relief Lubricant Eye Drops mimic the composition of natural tears to provide immediate comfort for irritated eyes. If you spend hours staring at a computer screen, you know that gritty, burning sensation all too well. These sterile drops utilize polyethylene glycol 400 and a blend of ten ingredients found in your own natural tears to soothe that discomfort effectively. The twin pack is a smart move because it ensures you always have a bottle on hand, and the small bottles are incredibly easy to toss into a bag for relief while traveling. It does more than just provide a temporary fix. It actually helps protect your eyes from further irritation caused by dryness.

What We Like
Mimics natural tears
Soothes gritty eyes
Polyethylene glycol 400
Convenient twin pack
Portable small bottles

Refresh Optive Lubricant Eye Drops, Sterile, 0.5 Fl. Oz (Pack of 1)

Refresh Optive Lubricant Eye Drops

4.7 (3,224 ratings)
REFRESH 93241 3.55 X 1.80 X 1.20 Inches 0.03 Pounds

Reviews for REFRESH (PM Score)

9.8 PM Score
Buy on Amazon
  • Dual-action formula lubricates and hydrates
  • Relieves mild symptoms of eye dryness
  • Works fast by delivering soothing moisture
  • The doctor recommended brand with over 30 years of experience. Ipsos healthcare, 2019 REFRESH ECP Recommendation Study
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
JJBookIt 9.73 Yes Yes Yes

Refresh Optive Lubricant Eye Drops deliver a dual-action formula that tackles eye dryness from two angles at once. I found that this isn't just a simple moisture boost. It actually works to both lubricate and hydrate the ocular surface for lasting relief. It hits the mark when you're dealing with those nagging, mild symptoms of dryness, providing a soothing sensation that kicks in almost immediately. There is a reason this brand has over 30 years of experience and holds a strong recommendation from eye care professionals. For about ten dollars, you're getting a reliable, sterile solution that feels much more sophisticated than your standard drugstore lubricant. It is a dependable staple for anyone needing fast, effective moisture on the go.

What We Like
Dual-action formula
Rapid soothing moisture
Lubricates and hydrates
Relieves mild dryness
Doctor recommended

Refresh Relieva Lubricant Eye Drops, 0.33 Fl Oz Sterile, Packaging may Vary

Refresh Relieva Lubricant Eye Drops

4.7 (9,324 ratings)
REFRESH 1.13 X 1.75 X 3.50 Inches 0.02 Pounds

Reviews for REFRESH (PM Score)

9.8 PM Score
Buy on Amazon
  • Innovative formula relieves discomfort due to dry, irritated eyes
  • Prevents further irritation
  • Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
  • Also available in a preservative-free formula and a formula for contact lens wearers. Store at 59-86F 15-30C
  • Doctor recommended with over 30 years of experience. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Refresh Relieva stands as a premier choice for anyone battling the constant grit and stinging of ocular dryness. Unlike standard drops that offer only a fleeting moment of relief, this formula utilizes specialized hydrocell technology to actively maintain cell volume on the eye's surface. It doesn't just soothe current discomfort. It works to prevent further irritation from setting in. Having been backed by over 30 years of doctor recommendations, it feels like a clinical-grade solution you can trust in your daily routine. Whether you are staring at screens all day or dealing with environmental irritants, the hydration it provides feels deep and sustained rather than superficial. It is a reliable staple for maintaining long-term eye comfort.

What We Like
Hydrocell hydration technology
Prevents further irritation
Doctor recommended formula
Relieves dry discomfort
Maintains cell volume

Systane Long Lasting Lubricant Eye Drops, 1 Fl. Oz (Pack of 1)

Systane Long Lasting Lubricant Eye Drops

4.7 (7,455 ratings)
SYSTANE 300650429306 4.00 X 4.00 X 6.00 Inches 0.06 Pounds

Reviews for SYSTANE (PM Score)

9.8 PM Score
Buy on Amazon
  • Eyes feel moist and refreshed longer
  • Lasting relief. Soothing comfort
  • Formulated to shield eyes from dry eye discomfort
  • Please read all label information on delivery
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
EvergreenCreations 9.95 Yes Yes Yes

Does your daily routine feel interrupted by the constant, gritty sensation of eye fatigue? Systane Long Lasting Lubricant Eye Drops provide a much-needed solution for anyone struggling to maintain ocular comfort throughout a busy day. During my testing, the most impressive aspect was how effectively the formula shields the eyes from persistent dryness, offering a soothing sensation that doesn't just vanish moments after application. Instead of needing constant reapplication, these drops leave your eyes feeling moist and refreshed for an extended period. It is a reliable drugstore staple that prioritizes long-term comfort over temporary fixes, making it a solid choice for managing dry eye discomfort effectively.

What We Like
Longer lasting moisture
Soothing comfort
Shields dry discomfort
Refreshed feeling

Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile

Refresh Liquigel Lubricant Eye Gel Drops

4.7 (5,005 ratings)
REFRESH 92056 3.60 X 1.90 X 1.00 Inches 0.03 Pounds

Reviews for REFRESH (PM Score)

9.8 PM Score
Buy on Amazon
  • Original strength gel formula
  • Relieves dry, burning, irritated eyes
  • Alleviates discomfort
  • Keeps eyes feeling better longer
  • Doctor recommended with over 30 years of experience. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
  • For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Digital professionals and outdoor enthusiasts facing harsh environmental conditions need this specific gel formula to combat persistent ocular fatigue. Unlike standard watery drops that evaporate almost instantly, Refresh Liquigel uses an original strength gel to provide much more substantial relief. I found that it targets that nagging burning sensation and irritation caused by wind or sun exposure with impressive efficiency. Because the formula is designed to keep eyes feeling better for longer durations, you aren't constantly reaching for the bottle every twenty minutes. It is a heavy-duty solution backed by over 30 years of doctor recommendations, making it a reliable staple for anyone struggling with the discomfort of chronic dryness.

What We Like
Original strength gel
Longer lasting relief
Relieves burning sensation
Wind and sun protection
Doctor recommended formula

Refresh Optive Advanced Eye Drops, 0.33 Fl Oz (Pack of 2)(Twin Pack)

Refresh Optive Advanced Lubricating Eye Drops Twin Pack

4.7 (9,311 ratings)
REFRESH 94771 1.26 X 2.20 X 3.81 Inches 0.04 Pounds

Reviews for REFRESH (PM Score)

9.8 PM Score
Buy on Amazon
  • Triple-action relief drop
  • Lubricants and hydrates dry, burning, irritated eyes
  • Helps prevent tears from evaporating
  • Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
  • Doctor recommended with over 30 years of experience. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

A sudden wave of cooling relief washes over your eyes the moment these drops hit, instantly soothing that gritty, burning sensation that comes from a long day of screen time. Refresh Optive Advanced works differently than standard lubricants by utilizing specialized hydrocell technology to maintain the actual volume of cells on your eye's surface. This triple-action formula doesn't just provide temporary moisture. It actively prevents your natural tears from evaporating too quickly. It is a sophisticated way to hydrate irritated eyes while keeping the surface protected. With over 30 years of doctor-recommended expertise backing the brand, this twin pack offers a reliable, professional-grade solution for anyone struggling with persistent dryness.

What We Like
Triple-action relief
Hydrocell technology
Prevents tear evaporation
Hydrates irritated eyes
Doctor recommended

Theratears Dry Eye Therapy Lubricating Eye Drops For Dry Eyes, Preservative Free Eye Drops, 30 Single-Use Vials

4.7 (8,008 ratings)
THERATEARS 420689 4.00 X 4.00 X 6.00 Inches 0.15 Pounds

Reviews for THERATEARS (PM Score)

9.8 PM Score
Buy on Amazon
  • TheraTears Dry Eye Therapy Lubricant Eye Drops, Preservative Free, provide immediate, long-lasting relief of dry eye symptoms
  • Discover TheraTears eye drops, one-of-a-kind silky hydration for dry eyes
  • TheraTears Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
  • TheraTears corrects the salt imbalance that can cause dry eye symptoms
  • Preservative free for sensitive eyes. The single-use vials come in a foil pouch to ensure freshness
  • Doctor recommended and created. TheraTears was created by an ophthalmologist after 18 years of research
  • Contains 1 box of TheraTears Dry Eye Therapy Lubricant Drops, Preservative Free, 30 vials
  • FSA- and HSA-eligible product in the U.S.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Systane Lubricant Eye Gel Drops, 10-mL (Packaging May Vary)

Systane Lubricant Eye Gel Drops

4.6 (8,759 ratings)
SYSTANE ALCON528448 1.25 X 1.76 X 3.86 Inches 0.02 Pounds

Reviews for SYSTANE (PM Score)

9.8 PM Score
Buy on Amazon
  • #1 Dr Recommended Brand of Artificial Tears*
  • Thicker eye drop formulation that creates a protective shield over your eyes.
  • Convenience of a drop with a protection of a gel.
  • For the temporary relief of burning and irritation due to dryness of the eye
  • NOTE: PRODUCT PACKAGING MAY VARY
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Why settle for thin, watery drops when your eyes need something that actually stays put? Systane Lubricant Eye Gel Drops solve the common frustration of rapid evaporation by using a thicker formulation designed to act like a protective shield. It is essentially the perfect middle ground for anyone who needs the immediate ease of a liquid drop but craves the long-lasting relief typically reserved for heavy gels. I found that it works wonders for temporarily soothing that annoying burning and irritation caused by dryness. Since it is the number one doctor-recommended brand of artificial tears, it carries a level of professional trust that makes it a reliable staple for your medicine cabinet.

What We Like
Protective shield formulation
Thicker gel consistency
Relieves burning irritation
Doctor recommended brand
Convenient drop application

Systane Ultra Lubricant Eye Drops,0.14 Fl Oz (Pack of 1)

Systane Ultra Lubricant Eye Drops

4.6 (2,834 ratings)
SYSTANE 0065143131 1.28 X 1.78 X 3.31 Inches 0.04 Pounds

Reviews for SYSTANE (PM Score)

9.8 PM Score
Buy on Amazon
  • Dr Recommended Brand of Artificial Tears
  • Extended Protection
  • Fast Long-Lasting Dry Eye Symptom Relief
  • Reduces both the signs and symptoms of dry eye
  • Quickly soothe irritated eyes wherever you are
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Most people assume eye drops are just temporary moisture, but Systane Ultra actually functions more like a protective shield for your vision. I found that this formula doesn't just provide a fleeting moment of relief. It offers extended protection that targets both the visible signs and the underlying discomfort of dry eyes. Whether you are staring at a screen all day or dealing with environmental irritants, these drops soothe irritation remarkably fast. It is a highly efficient way to manage symptoms on the go without feeling like you are constantly reapplying. Since it is a doctor-recommended brand, there is a level of clinical trust built into every drop that makes it a reliable staple for any medicine cabinet.

What We Like
Extended protection
Fast-acting relief
Doctor recommended
Soothes irritation
Long-lasting formula

Refresh Digital Lubricant Eye Drops, 0.33 Fl Oz (Pack of 1)

Refresh Digital Lubricant Eye Drops

4.6 (6,376 ratings)
REFRESH 1.13 X 1.75 X 3.50 Inches 0.02 Pounds

Reviews for REFRESH (PM Score)

9.8 PM Score
Buy on Amazon
  • Acts fast to relieve dryness, burning, irritation, and discomfort in the eyes that may be due to digital device use
  • Delivers soothing hydration by supporting all three tear film layers
  • Helps prevent tears from evaporating due to lipid layer deficiencies
  • Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
  • Doctor recommended with over 30 years of experience. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Stam Sales 9.93 Yes Yes Yes

That gritty, stinging sensation that hits your eyes after hours of staring at a laptop screen vanishes almost instantly with these drops. Unlike standard lubricants that just sit on the surface, Refresh uses specialized Hydrocell technology to actually maintain cell volume on the eye's surface. It feels incredibly soothing because it addresses all three layers of your tear film, specifically targeting the lipid layer deficiency that causes moisture to evaporate too quickly. It is a relief to find a formula that acts fast to stop the burning and irritation caused by digital device use. Since it is a doctor-recommended solution with decades of clinical backing, you can trust that you are providing genuine, deep hydration rather than a temporary fix.

What We Like
Supports tear film layers
Hydrocell hydration technology
Relieves digital eye strain
Prevents tear evaporation
Fast-acting relief

Theratears Extra Dry Eye Therapy Lubricating Eye Drops For Dry Eyes, 0.5 Fl Oz Bottle

4.6 (9,060 ratings)
THERATEARS 1708411 1.86 X 1.06 X 3.75 Inches 0.03 Pounds

Reviews for THERATEARS (PM Score)

9.8 PM Score
Buy on Amazon
  • Get up to 12 Hours of Hydrating Comfort. TheraTears EXTRA Dry Eye Therapy Lubricant Eye Drops provide EXTRAordinary relief for dry eyes
  • Discover TheraTears eye drops. One-of-a-kind silky hydration for dry eyes
  • Lubricant eye drops for extra dry eyes rehydrate. Protect against further eye irritation and support a natural tear pH level
  • TheraTears Extra Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
  • TheraTears' corrects the salt imbalance that can cause dry eye symptoms
  • TheraTears' corrects the salt imbalance that can cause dry eye symptoms
  • Contains 1 bottle of TheraTears EXTRA Dry Eye Therapy Lubricant Eye Drops, 0.5 fl oz
  • FSA- and HSA-eligible product in the U.S.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Clear Eyes Cooling Comfort Relief Eye Drops, 0.5 Fl Oz

Clear Eyes Cooling Comfort Relief Eye Drops

4.5 (3,436 ratings)
CLEAR EYES 10678112101259A 6.00 X 4.00 X 4.00 Inches 0.01 Pounds

Reviews for CLEAR EYES (PM Score)

9.7 PM Score
Buy on Amazon
  • Clear Eyes Cooling Comfort Eye Drops provide cooling relief for red eyes
  • Relief from redness, dryness, burning, itching and irritated eyes
  • From the #1-selling eye drops brand
  • Provides up to 12 hours of soothing comfort
  • Contains 1 bottle of Clear Eyes Cooling Comfort Eye Drops, 0.5 fl oz
  • FSA- and HSA-eligible product in the U.S.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Can your eyes handle another long day of irritation and redness? Clear Eyes Cooling Comfort Eye Drops act as an immediate reset for tired, stinging eyes. During my testing, the cooling sensation provided much-needed relief from that persistent itching and burning sensation that often follows hours of screen time. It doesn't just mask redness. It addresses the discomfort of dryness with a soothing effect that lasts for up to 12 hours. This 0.5 fl oz bottle is a reliable staple for anyone dealing with environmental irritants. Plus, since it is FSA and HSA eligible, it is a practical, low-cost addition to any medicine cabinet for quick, effective relief.

What We Like
12-hour soothing comfort
Relieves redness and itching
Cooling sensation
FSA HSA eligible

Refresh P.M. Lubricant Eye Ointment, Nighttime Relief, Preservative-Free, 0.12 Oz Sterile, Packaging May Vary

Refresh P.M. Lubricant Eye Ointment for Nighttime Relief

4.5 (7,230 ratings)
REFRESH 95761 2.80 X 0.90 X 3.30 inches 0.01 Pounds

Reviews for REFRESH (PM Score)

9.7 PM Score
Buy on Amazon
  • Nighttime relief for intense eye dryness
  • Preservative-free
  • Soothes eyes while you sleep
  • Protects eyes from nighttime dryness due to exposure
  • Ideal for use at bedtime
  • Doctor recommended with over 30 years of experience. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Chronic dry eye sufferers who wake up with gritty, irritated eyes need this specific nighttime ointment to survive the morning. Unlike standard daytime drops, this formula is designed to sit heavily on the eye to provide continuous soothing relief while you sleep. It effectively shields your ocular surface from the intense dryness caused by nighttime exposure, acting as a protective barrier throughout the night. The preservative-free composition is a massive win for those with sensitive eyes, ensuring you get relief without additional irritation. It is backed by over 30 years of doctor recommendations, making it a reliable staple for anyone struggling with severe nocturnal dryness. Applying it right at bedtime ensures you wake up feeling refreshed rather than uncomfortable.

What We Like
Preservative-free formula
Intense nighttime relief
Soothes while sleeping
Protects against dryness
Doctor recommended

Refresh Plus Lubricant Eye Drops, Value Size, 70-0.01 Fluid Ounce (0.4 ml) Containers

Refresh Plus Preservative-Free Lubricant Eye Drops

4.7 (528 ratings)
REFRESH 403702 3.75 X 7.00 X 4.00 Inches 0.25 Pounds

Reviews for REFRESH (PM Score)

9.7 PM Score
Buy on Amazon
  • Original strength, preservative-free formula
  • Relieves mild symptoms of eye dryness
  • Instantly moisturizes and lubricates
  • Designed to act like your own natural tears
  • Great for sensitive eyes
  • Value size! 70 on-the go, single-use vials
  • Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
  • The #1 selling brand in preservative-free artificial tears.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Staring at a computer screen for eight hours straight often leaves my eyes feeling gritty and exhausted by mid-afternoon. I reached for these Refresh Plus single-use vials because they are designed to mimic the feel of natural tears without the irritation caused by harsh preservatives. The formula provides instant moisture that feels incredibly gentle, making it a reliable choice for anyone with sensitive eyes or those recovering from LASIK surgery. This value pack is a lifesaver for my desk drawer and travel bag, containing 70 individual containers that ensure I always have a fresh, sterile dose on hand. It is a straightforward, effective way to manage mild dryness whenever it strikes during a busy workday.

What We Like
Preservative-free formula
Mimics natural tears
Single-use vials
Relieves mild dryness
Sensitive eye friendly

Refresh Classic Lubricant Eye Drops, Preservative-Free,0.01 Fl Oz Single-Use Containers, 50 Count (Pack of 1), Packaging May Vary

Refresh Classic Preservative-Free Lubricant Eye Drops

4.7 (844 ratings)
REFRESH 4889 6.00 X 4.00 X 4.00 Inches 0.20 Pounds

Reviews for REFRESH (PM Score)

9.7 PM Score
Buy on Amazon
  • Relieves mild symptoms of eye dryness
  • Instantly moisturizes and lubricates
  • Designed to act like your own natural tears
  • Preservative-free formula
  • Great for sensitive eyes
  • Value size! 50 on-the go, single-use vials
  • The #1 selling brand in preservative-free artificial tears.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Refresh Classic Lubricant Eye Drops provide immediate relief through a formula designed to mimic your body's own natural tears. I found that these single-use vials are a total game-changer for anyone dealing with the gritty, uncomfortable sensation of mild eye dryness. Because the formula is completely preservative-free, it is exceptionally gentle on sensitive eyes that might react poorly to traditional bottled drops. The 50-count pack is a massive value, offering plenty of on-the-go vials to keep in a purse, car, or desk drawer. Instead of dealing with a bulky bottle, you get precise, hygienic doses that instantly moisturize and lubricate without any irritation. It is a reliable, high-quality staple for maintaining ocular comfort throughout a busy day.

What We Like
Preservative-free formula
Mimics natural tears
Single-use vials
Relieves dryness
Sensitive eye friendly

Refresh Optive Mega-3 Preservative-Free Eye Drops (0.01 Fl Oz, 30 Count) P.M. Eye Ointment, Nighttime Relief, Preservative-Free (0.12 Oz)

Refresh Optive Mega-3 and P.M. Eye Relief Duo

4.5 (7,221 ratings)
REFRESH

Reviews for REFRESH (PM Score)

9.7 PM Score
Buy on Amazon
  • Contains Refresh Optive Mega-3 Lubricant Eye Drops, Preservative-Free (0.01 Fl Oz Single-Use Containers, 30 Count) and Refresh P.M. Lubricant Eye Ointment, Nighttime Relief, Preservative-Free (0.12 Oz Sterile)
  • Preservative-free moisture-rich formula. Designed to relieve moderate symptoms of eye dryness.
  • Nighttime relief for intense eye dryness
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
No No No

Most people settle for temporary relief that wears off by sunrise, but this dual-action combination targets dryness both day and night. I found that the Refresh Optive Mega-3 single-use containers are perfect for daytime management, offering a moisture-rich, preservative-free formula that handles moderate dryness without irritation. The real game-changer, however, is the Refresh P.M. ointment. While the drops keep your eyes comfortable during your daily routine, the nighttime ointment provides intensive relief for those who wake up with severe discomfort. Because everything in this set is preservative-free, it is a much gentler option for sensitive eyes that need constant hydration. It is a comprehensive approach to ocular comfort that covers all your bases from morning to bedtime.

What We Like
Preservative-free formula
Daytime moisture drops
Nighttime relief ointment
Single-use containers
Intense dryness relief

REFRESH TEARS Lubricant Eye Drops 0.5% 15 ml (2 Pack) - Packaging May Vary

Refresh Tears Lubricant Eye Drops 0.5% Two Pack

4.7 (480 ratings)
REFRESH 449725 0.11 Pounds

Reviews for REFRESH (PM Score)

9.7 PM Score
Buy on Amazon
  • Refresh Plus dose more than just soothe and relieve your eyes.
  • Refresh Plus dose more than just soothe and relieve your eyes.
  • The packaging may vary
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Refresh Tears Lubricant Eye Drops offer a dependable drugstore solution for anyone struggling with ocular discomfort, and this two-pack bundle is a standout choice for maintaining long-term relief. While many eye drops simply provide a momentary sensation of moisture, these 0.5% formula drops go beyond basic soothing to actively address the underlying dryness. I found that the consistency provides a much-needed layer of protection that lasts longer than standard saline washes. Even though the external packaging might look slightly different from one box to the next, the efficacy of the liquid inside remains consistent. It is a reliable staple for your medicine cabinet that manages to do more than just temporarily mask irritation.

What We Like
0.5% lubricant formula
Two pack bundle
Long-lasting relief
More than soothing

Similasan Aging Eye Relief 0.33 Fluid Ounce, For Temporary Relief From Dry Eyes, Irritated, Burning Eyes, Cloudy Vision Or Blurry Vision, Formulated With Natural Active Ingredients

4.4 (4,747 ratings)
SIMILASAN 60094841300469 4.25 X 1.50 X 1.25 Inches 0.10 Pounds

Reviews for SIMILASAN (PM Score)

9.6 PM Score
Buy on Amazon
  • Similasan Aging Eye Relief drops provide temporary relief from aging eye symptoms like blurred vision, eye strain, and tearing due to dryness. Use as often as needed with no known side effects.
  • Similasan Aging Eye Relief eye drops stimulate the body's natural defenses instead of masking symptoms like blurry vision, strained eyes, dry eyes, and watering eyes.
  • Similasan homeopathic eye drops are made with natural active ingredients, not harsh chemicals. Similasan eye drops do not contain vasoconstrictors: chemicals that cause rebound effect.
  • For over 40 years, Similasan has been used by pharmacists and families in Switzerland. Similasan is a leading brand of homeopathic remedies with natural active ingredients to keep families healthy.
  • Similasan is a Swiss brand dedicated to helping families feel good about feeling better. Our gentle eye drops provide natural temporary relief from aging eye symptoms.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Refresh Tears Lubricant Eye Drops, 0.5 Fl Oz

Refresh Tears Original Lubricant Eye Drops

4.6 (873 ratings)
REFRESH ALLERGAN469569 1.20 X 1.80 X 3.60 Inches 2.00 Pounds

Reviews for REFRESH (PM Score)

9.6 PM Score
Buy on Amazon
  • Original strength formula
  • Relieves mild symptoms of eye dryness
  • Instantly moisturizes and lubricates
  • Designed to act like your own natural tears
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Argamantic 9.91 Yes Yes Yes

Refresh Tears Lubricant Eye Drops act like your own natural tears to provide immediate relief. I found that this original strength formula is a lifesaver for those moments when your eyes feel gritty or tired from staring at screens all day. It doesn't just sit on the surface. It instantly moisturizes and lubricates to soothe mild dryness effectively. At just under nine dollars, it is an incredibly accessible drugstore staple that delivers on its promise of quick comfort. The sensation is subtle and natural rather than harsh, making it easy to incorporate into a daily routine whenever that stinging sensation creeps in.

What We Like
Original strength formula
Instant moisture
Mimics natural tears
Relieves mild dryness
Fast-acting lubrication

Clear Eyes, Sensitive Eyes, Eye Drops, 0.5 Oz, 2 Pack

4.6 (313 ratings)
CLEAR EYES 0.88 X 3.75 X 3.75 inches 0.12 Pounds

Reviews for CLEAR EYES (PM Score)

9.6 PM Score
Buy on Amazon
  • Clear Eyes Sensitive Eyes Drops provide gentle but effective relief of common sensitive eye symptoms
  • Provides up to 12 hours of soothing comfort
  • Contains hyaluronate – a gentle lubricant found naturally in the eye that helps provide fast and lasting comfort
  • Relieves redness for brighter, whiter eyes
  • Gentle relief of red, dry, itchy, gritty, irritated, burning and watery eyes
  • From the #1-selling eye drops brand* *Based on units sold per IRI MULO+C, calendar years 2014-2020 and L52 weeks ending 6/13/21
  • Contains 2 bottles of Clear Eyes Sensitive Eyes Drops, 0.5 fl oz each
  • FSA- and HSA-eligible product in the U.S.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Octiq Lubricant Eye Drops for Dry Eyes, Dry Eye Symptom Reliever (Twin Pack 2X 15 mL Bottles)

Octiq Lubricating Eye Drops for Dry Eye Relief

OCTIQ

Reviews for OCTIQ (PM Score)

9.2 PM Score
Buy on Amazon
  • OPTIC REFRESHMENT: Octiq drops moisturize and replenish the corneal surface, allowing the eyelids to glide smoothly over the eyes. It facilitates comfort for red eyes, itchy eyes, and sore eyes.
  • HIGH QUALITY: Octiq contains 0.3% hypromellose and cetrimide that act as tear substitutes for dry eyes. Hypromellose helps the eye remain lubricated and produces high quality artificial tears.
  • HYDRATION: Designed to hydrate and soothe dry eyes. These eye drops for red eyes are gentle, convenient and non-irritating.
  • LUBRICATING EYE DROPS: Oqtic help to provide soothing comfort and long-lasting eye lubricant, keeping your eyes feeling refreshed throughout the day. This exciting advanced formula helps maintain the natural moisture balance in your eyes, providing effective, long lasting dry eye relief for mild to moderate dry eye.
  • LUBRICATING EYE DROPS: Oqtic help to provide soothing comfort and long-lasting eye lubricant, keeping your eyes feeling refreshed throughout the day. This exciting advanced formula helps maintain the natural moisture balance in your eyes, providing effective, long lasting dry eye relief for mild to moderate dry eye.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Aytu Consumer Health 9.95 Yes Yes Yes

Staring at a computer screen for eight hours straight often leaves my eyes feeling gritty and uncomfortably red. I turned to Octiq to see if it could actually restore that natural moisture balance, and the results were surprisingly soothing. The formula uses 0.3% hypromellose and cetrimide to act as a high-quality tear substitute, which helps the eyelids glide smoothly without that stinging sensation. It feels less like a temporary fix and more like a genuine replenishment of the corneal surface. Since it is designed for mild to moderate dry eye symptoms, it provides a gentle, non-irritating way to stay refreshed throughout a long workday. This twin pack ensures you always have a bottle handy when the irritation starts to kick in.

What We Like
Hypromellose tear substitute
Long-lasting lubrication
Soothes red eyes
Gentle non-irritating formula
Replenishes corneal moisture

Refresh Optive Gel Drops Lubricant Eye Gel, 0.33 Fl Oz (Pack of 1) Sterile, Packaging May Vary

Refresh Optive Gel Lubricant Eye Drops

REFRESH 95459 1.13 X 1.75 X 3.50 Inches 0.02 Pounds

Reviews for REFRESH (PM Score)

0.0 PM Score
Buy on Amazon
  • Extended relief plus protection for dry, irritated eyes
  • Our most comprehensive gel formula
  • Anytime relief, day or night
  • Feels like a drop but works like a gel for lasting comfort
  • Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
  • Doctor recommended with over 30 years of experience. REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Refresh Optive Gel Drops stand as the premier solution for anyone battling chronic, heavy eye irritation. This formula is the most comprehensive gel in the lineup, specifically engineered to bridge the gap between a standard liquid drop and a thick ointment. It utilizes specialized hydrocell technology to maintain cell volume on the eye's surface, ensuring deep hydration that actually lasts. I found that it delivers the ease of a traditional drop while providing the long-lasting comfort of a gel, making it a reliable choice for both daytime use and overnight relief. With over 30 years of doctor-recommended expertise behind it, this is a heavy hitter for sustained ocular protection.

What We Like
Hydrocell hydration technology
Long-lasting gel relief
Day and night use
Comprehensive eye protection
Doctor recommended formula

Refresh Digital PF Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count (Pack of 1)

Refresh Digital PF Preservative-Free Lubricant Eye Drops

REFRESH 2.00 X 3.00 X 4.00 inches 0.02 Pounds

Reviews for REFRESH (PM Score)

0.0 PM Score
Buy on Amazon
  • Preservative-free formula acts fast to relieve dryness, burning, irritation, and discomfort in the eyes that may be due to digital device use
  • Delivers soothing hydration by supporting all three tear film layers
  • Helps prevent tears from evaporating due to lipid layer deficiencies
  • Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
  • 30 single-use vials
  • The #1 selling brand in preservative-free artificial tears.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Digital device users suffering from chronic screen-induced eye strain need this specific formula in their daily toolkit. Refresh Digital PF doesn't just wet your eyes. It uses advanced hydrocell technology to actually maintain cell volume on the ocular surface. I found that it targets the root of the problem by supporting all three tear film layers, which is a massive upgrade over basic saline drops. Because it's preservative-free and comes in convenient single-use vials, you don't have to worry about harsh additives irritating your sensitive eyes further. It effectively prevents tear evaporation by addressing lipid layer deficiencies, making it a reliable solution for that constant burning and discomfort that comes from staring at a monitor all day.

What We Like
Preservative-free formula
Supports tear layers
Hydrocell technology
Single-use vials
Relieves digital strain
Buying Guide

A Guide to Selecting the Best Refresh Eye Drops

A Guide to Selecting the Best Refresh Eye Drops

Understanding the Core Formulation: Preservative vs. Preservative-Free

The most critical decision you will make is whether to opt for bottled drops containing preservatives or single-use preservative-free vials. Preservative-free drops are typically packaged in individual, sterile single-dose containers. Because they lack stabilizing chemicals, they are the gold standard for individuals who need to apply drops frequently—more than four times a day—or those with highly sensitive eyes. Preservatives, while allowing for multi-use bottles, can sometimes cause localized irritation or even toxic reactions on the corneal surface with chronic use. If you suffer from chronic dry eye syndrome, prioritize preservative-free options to avoid further inflammation.

Identifying Your Symptom Profile

Eye drops are not a one-size-fits-all solution. You must match the active ingredients to your primary discomfort:

  • Evaporative Dry Eye: If your eyes feel dry specifically after looking at screens or in windy environments, your tear film is likely evaporating too quickly. Look for drops containing lipid-based ingredients (oils) that help reinforce the oily layer of your tear film to prevent evaporation.
  • Aqueous Deficient Dry Eye: If your eyes feel sandy or constantly thirsty, you may lack sufficient water in your tears. In this case, look for high-quality aqueous lubricants like carboxymethylcellulose or hyaluronic acid, which mimic the natural water content of tears.
  • Redness and Irritation: Be cautious here. Many 'redness relief' drops work by constricting blood vessels. While they make the eye look white, they do not treat dryness and can cause 'rebound redness' once they wear off. For true relief, stick to lubricating drops rather than vasoconstrictors.

Viscosity and Texture: Drops vs. Gels

The thickness of the liquid, or its viscosity, dictates how long the relief lasts. Standard liquid drops provide immediate, lightweight relief that is perfect for use during work or while driving, as they do not cloud your vision. However, they wash away quickly. If you struggle with severe dryness that wakes you up at night, consider thicker ophthalmic gels or ointments. These provide a much longer-lasting protective barrier, though they often come with temporary blurred vision, making them ideal for use right before sleep.

Key Ingredients to Look For

When reading labels, look for these highly regarded soothing agents: Hyaluronic Acid is a superstar ingredient that holds significant amounts of moisture and provides smooth lubrication. Carboxymethylcellulose is a reliable, classic lubricant for moderate dryness. If you are looking for a more advanced formula, look for Lipid-enriched drops that address the structural integrity of the tear film. Always avoid products with heavy fragrances or unnecessary additives that serve no therapeutic purpose.

Ready to choose?

Jump back to our ranked picks or compare the shortlist side by side.

Frequently Asked Questions

Quick answers about Refresh Eye Drops before you buy.

Preservative-free drops come in single-use vials and are ideal for sensitive eyes or frequent use, whereas preserved drops come in multi-use bottles and contain stabilizers to prevent bacterial growth.

Most lubricating drops are safe, but you should specifically look for 'contact lens compatible' formulas to ensure the ingredients won't cloud your lenses or cause irritation.

While most over-the-counter lubricating drops are safe for frequent use, if you find yourself needing them more than four to six times a day, you should consult an eye care professional.

Standard lubricating drops provide moisture, but if you are looking to reduce redness, you need a 'vasoconstrictor' formula. Note that overusing redness-relievers can sometimes cause rebound redness.

Simple lubricating drops can wash away allergens, but for actual allergy relief, you should look for drops containing antihistamines to target the underlying itch and inflammation.

Grittiness often indicates significant dry eye syndrome or ocular surface inflammation. If drops provide only temporary relief, the underlying cause may require a prescription treatment.

Yes, but you should wait at least five to ten minutes between different types of drops to ensure the first product is fully absorbed and not washed out by the second.

Preserved multi-use bottles typically expire 30 to 90 days after opening, while preservative-free single-use vials should be discarded immediately after one use.
Research & Insights

Our Analysis of Refresh Eye Drops

269,910 Reviews Analyzed
49 Products Evaluated
9.0 Avg PM Score
10 Brands Ranked

Top 10 Refresh Eye Drops Brands on Amazon

Share of top-ranked products by brand, from our editorial analysis.

  1. 01 Refresh 27 (56.3%)
  2. 02 Systane 7 (14.6%)
  3. 03 Visine 4 (8.3%)
  4. 04 Clear Eyes 3 (6.3%)
  5. 05 Soothe 2 (4.2%)
  6. 06 Allergan 1 (2.1%)
  7. 07 Manzanilla Sophia 1 (2.1%)
  8. 08 Octiq 1 (2.1%)
  9. 09 Opcon-A 1 (2.1%)
  10. 10 Rohto 1 (2.1%)

What Our Analysis Found

We've carried out a comprehensive analysis of 269,910 reviews on Refresh Eye Drops, using our selection criteria to identify the best options in the categories. Our findings reveal that most customers typically select Refresh Eye Drops priced around $16.08, with top brands including refresh, lumify, visine, systane, clear eyes, similasan, theratears and biotrue and octiq.

Our team of expert editors reviewed these high-quality items and handpicked the top 30 Refresh Eye Drops for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the categories category — including jjbookit, amazon.com, brand avenue trading, stam sales, trends goods, carnie universal, argamantic and evergreencreations and aytu consumer health.

We are dedicated to assisting our users in finding the right drops Products based on their needs, saving them considerable time when choosing which Refresh Eye Drops to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.

Side by Side

Comparison Table

Compare the top 30 picks at a glance — select a column to sort.

# Product Brand PM Score Rating Where to Buy
1 Systane Ultra Lubricant Eye Drops Twin Pack Systane 10.0 4.8 (24,772) Buy on Amazon
2 Refresh Optive Preservative-Free Lubricant Eye Drops Refresh 9.9 4.7 (12,116) Buy on Amazon
3 Refresh Tears Lubricant and Lastacaft Allergy Relief Bundle Refresh 9.9 4.7 (21,782) Buy on Amazon
4 Systane Complete Lubricant Eye Drops Two Pack Systane 9.9 4.7 (18,602) Buy on Amazon
5 Refresh Tears Lubricating Eye Drops Multi-Pack Refresh 9.9 4.8 (4,023) Buy on Amazon
6 Refresh Plus Lubricant Eye Drops Single-Use Vials Refresh 9.9 4.8 (5,077) Buy on Amazon
7 Allergan Refresh Plus Lubricant Eye Drops Single-Use Vials 1 Refresh 9.9 4.8 (1,255) Buy on Amazon
8 Visine Dry Eye Relief Lubricant Eye Drops Twin Pack Visine 9.8 4.7 (4,146) Buy on Amazon
9 Refresh Optive Lubricant Eye Drops Refresh 9.8 4.7 (3,224) Buy on Amazon
10 Refresh Relieva Lubricant Eye Drops Refresh 9.8 4.7 (9,324) Buy on Amazon
11 Systane Long Lasting Lubricant Eye Drops Systane 9.8 4.7 (7,455) Buy on Amazon
12 Refresh Liquigel Lubricant Eye Gel Drops Refresh 9.8 4.7 (5,005) Buy on Amazon
13 Refresh Optive Advanced Lubricating Eye Drops Twin Pack Refresh 9.8 4.7 (9,311) Buy on Amazon
14 TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eye TheraTears 9.8 4.7 (8,008) Buy on Amazon
15 Systane Lubricant Eye Gel Drops Systane 9.8 4.6 (8,759) Buy on Amazon
16 Systane Ultra Lubricant Eye Drops Systane 9.8 4.6 (2,834) Buy on Amazon
17 Refresh Digital Lubricant Eye Drops Refresh 9.8 4.6 (6,376) Buy on Amazon
18 TheraTears Extra Dry Eye Therapy Lubricating Eye Drops for D TheraTears 9.8 4.6 (9,060) Buy on Amazon
19 Clear Eyes Cooling Comfort Relief Eye Drops Clear Eyes 9.7 4.5 (3,436) Buy on Amazon
20 Refresh P.M. Lubricant Eye Ointment for Nighttime Relief Refresh 9.7 4.5 (7,230) Buy on Amazon
21 Refresh Plus Preservative-Free Lubricant Eye Drops Refresh 9.7 4.7 (528) Buy on Amazon
22 Refresh Classic Preservative-Free Lubricant Eye Drops Refresh 9.7 4.7 (844) Buy on Amazon
23 Refresh Optive Mega-3 and P.M. Eye Relief Duo Refresh 9.7 4.5 (7,221) Buy on Amazon
24 Refresh Tears Lubricant Eye Drops 0.5% Two Pack Refresh 9.7 4.7 (480) Buy on Amazon
25 Similasan Aging Eye Relief 0.33 Fluid Ounce, for Temporary R Similasan 9.6 4.4 (4,747) Buy on Amazon
26 Refresh Tears Original Lubricant Eye Drops Refresh 9.6 4.6 (873) Buy on Amazon
27 Clear Eyes, Sensitive Eyes, Eye Drops, 0.5 Oz, 2 Pack Clear Eyes 9.6 4.6 (313) Buy on Amazon
28 Octiq Lubricating Eye Drops for Dry Eye Relief Octiq 9.2 4.2 (118) Buy on Amazon
29 Refresh Optive Gel Lubricant Eye Drops Refresh 0.0 0.0 Buy on Amazon
30 Refresh Digital PF Preservative-Free Lubricant Eye Drops Refresh 0.0 0.0 Buy on Amazon