Best Refresh Eye Drops in 2026

#1 Dr Recommended Brand of Artificial Tears*, packaging may vary

Extended Protection

Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature

Contains Refresh Tears Lubricant Eye Drops, 0.5 Fl Oz (2 Count) and Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count) 60 Day Supply

Original strength formula; Relieves mild symptoms of eye dryness

FAST-ACTING EYE ITCH RELIEF: Relieves itchy eyes from allergies in as little as 3 minutes

Eye Drops for Red Eyes: LUMIFY significantly reduces redness to help reveal your eyes' natural radiance. From the eye care experts at Bausch and Lomb, LUMIFY works in 1 minute and lasts up to 8 hours

LUMIFY is different: The only OTC drop to contain brimonidine. It selectively targets redness, alleviating some potential side effects associated with other redness relief drops, when used as directed

LUMIFY contains no bleach or dyes. It’s Doctor recommended redness reliever (data on file)

Preservative-free moisture-rich formula; On-the-go single use vials

Designed to relieve eye dryness that may be due to Meibomian Gland Dysfunction.

Delivers advanced hydration and lubrication

Original strength, preservative-free formula

Relieves mild symptoms of eye dryness

Instantly moisturizes and lubricates

Optimal dry eye relief

Nano-droplet technology takes our coverage to another level

Soothes eyes with fast-acting hydration

Clear eyes redness relief eye drops relieve redness from minor irritations and protect against further irritations

Soothes and moisturizes to relieve redness

Helps irritation, burning, and mild dry eyes

ALLERGY EYE DROPS: Opcon-A eye drops combine an antihistamine with redness reliever to help relieve itchy, red, irritated eyes. Temporarily relieves itching & redness caused by pollen, ragweed, grass, animal hair & dander

RELIEF FOR ITCHY EYES: Opcon-A eye drops are clinically proven to help temporarily relieve the redness & itching caused by symptoms of common airborne allergens like ragweed or grass

BAUSCH and LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops

0.5-fluid ounce bottle of Visine Red Eye Hydrating Comfort Redness Relief Eye Drops to offer eye redness relief in 30 seconds and lubricate irritated eyes

Formula contains 1% polyethylene glycol 400 and 0.05% tetrahydrozoline HCl which helps lubricate, refresh and relieve red irritated eyes

Fast-acting redness relief & moisturizing formula relieves symptoms due to minor eye irritations like exposure to smoke, lack of sleep and extended screen time and comes from Visine, a brand backed by 60 years of expertise

Original strength formula

Relieves mild symptoms of eye dryness due to contact lens wear

Instantly moisturizes and lubricates

Long-lasting relief plus protection

No preservatives

#1 Doctor recommended

For extended wear, frequent replacement, and disposable soft contact lenses

Sterile, isotonic solution

Soothes and moisturizes eyes for greater comfort

Innovative formula specially designed for contact lens wearers

Relieves mild to moderate symptoms of eye dryness, irritation, and discomfort associated with contact lens wear

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

Eyes feel moist and refreshed longer

Lasting relief; soothing comfort

Formulated to shield eyes from dry eye discomfort

Twin pack containing two 0.5-fluid ounce bottles of Visine Dry Eye Relief Lubricant Dry Eye Drops to provide dry eye relief and protection from further eye irritation

These sterile moisturizing eye drops provide soothing relief of dry, gritty and irritated eyes and are designed to work like real tears

The hydrating drops lubricate eyes, feature polyethylene glycol 400 and contain 10 ingredients found in your own natural tears

Original strength gel formula

Relieves dry, burning, irritated eyes

Alleviates discomfort

Preservative free dry-eye treatment

Saturates dry eye

For maximum relief

Safe to use as often as needed.

Remove contact lenses prior to use.

LONG LASTING, FAST RELIEF DRY EYE THERAPY: Use Soothe Lubricant Eye Drops to help moisturize & refresh dry eyes for long-lasting relief & comfort Formulated to relieve dryness of the eye & help prevent irritation

DRY EYE DROPS: Tear replacement drops are important to help relieve dry eye symptoms. Inactive Ingredients are boric acid, hydroxyalkylphosphonate, purified water, sodium alginate, sodium borate

BAUSCH + LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops

#1 Dr Recommended Brand of Artificial Tears*

Thickest gel formulation to coat the eye with a strong layer of dry eye symptom protection.

Provides long-lasting, nighttime protection while you sleep.

Acts fast to relieve dryness, burning, irritation, and discomfort in the eyes that may be due to digital device use

Delivers soothing hydration by supporting all three tear film layers

Helps prevent tears from evaporating due to lipid layer deficiencies

Nighttime relief for intense eye dryness

Soothes eyes while you sleep

Protects eyes from nighttime dryness due to exposure

Refresh Plus dose more than just soothe and relieve your eyes.

Refresh Plus dose more than just soothe and relieve your eyes.

The packaging may vary

Manzanilla Sophia’s homeopathic eye drops are formulated with the natural chamomile flower to soothe and cleanse your eyes without harmful chemicals.

Feel the gentle but powerful essence of chamomile rejuvenate your eyes with its relaxing properties.

Manzanilla Sophia eye drops refresh your eyes after excessive exposure to harsh weather, pollen, dust, and any other external impurity.

Relieves mild symptoms of eye dryness

Instantly moisturizes and lubricates

Designed to act like your own natural tears

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.

CONTACT LENS FRIENDLY: Biotrue Hydration Boost Eye Drops can be applied while wearing soft contact lenses.

INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.

HYDROGLOW TECHNOLOGY: Helping to improve the corneal surface of the eye, the technology soothes the eyes leaving them white and clear.

RELIEVING AND SOOTHING: The addition of menthol combines with other ingredients to create a very mild cooling sensation that refreshes the eyes.

MAXIMUM STRENGTH: Our Optic Glow formula offers the maximum strength allowed over the counter to help relieve the redness of the eyes due to dryness.

OPTIC REFRESHMENT: Octiq drops moisturize and replenish the corneal surface, allowing the eyelids to glide smoothly over the eyes. It facilitates comfort for red eyes, itchy eyes, and sore eyes.

HIGH QUALITY: Octiq contains 0.3% hypromellose and cetrimide that act as tear substitutes for dry eyes. Hypromellose helps the eye remain lubricated and produces high quality artificial tears.

HYDRATION: Designed to hydrate and soothe dry eyes. These eye drops for red eyes are gentle, convenient and non-irritating.

NEVER MISS A DROP: Whether you need eye drops for red-eye allergy relief, a prescribed antibiotic, saline solution, or artificial tears to help soothe dry eyes, you won’t have to worry about dripping anymore. With our eyedropper guide, you’ll get the drops in your eye every time. This makes it easy to take care of your eyes without a mirror.

GENTLE ON YOUR EYE: Our eye drop liquid guide was designed with your comfort in mind and is great for sensitive eyes. Its unique shape helps it fit over your eye without causing redness or irritation. It is oblong, with one rounded side and one side that comes to a point. The rounded side will fit perfectly between the bridge of your nose and your eye.

FITS ANY BOTTLE: Whether you are using a large dropper bottle or a mini, travel-sized bottle, they will both fit into our universal eye drop guide. It can also be used as an eye wash cup to refresh tired, sore eyes, to provide itch relief, or to dilute chemical irritants. Your new eyedropper guide is compact, making it perfect to keep in a purse or backpack for easy access.