Best Refresh Plus Eye Drops in 2026
Daisy
Last Updated: Jul 17, 2026
Daisy
Last Updated: Jul 17, 2026
* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ❌ |
Contains Refresh Tears Lubricant Eye Drops, 0.5 Fl Oz (2 Count) and Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count) 60 Day Supply
Original strength formula; Relieves mild symptoms of eye dryness
FAST-ACTING EYE ITCH RELIEF: Relieves itchy eyes from allergies in as little as 3 minutes
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Original strength, preservative-free formula
Relieves mild symptoms of eye dryness
Instantly moisturizes and lubricates
Designed to act like your own natural tears
Great for sensitive eyes
Value size: 50 on-the go, single-use vials
Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
The brand in preservative-free artificial tears; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Clear eyes redness relief eye drops relieve redness from minor irritations and protect against further irritations
Soothes and moisturizes to relieve redness
Helps irritation, burning, and mild dry eyes
Provides up to 12 hours of soothing comfort; Pack of 3
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
ALLERGY EYE DROPS: Opcon-A eye drops combine an antihistamine with redness reliever to help relieve itchy, red, irritated eyes. Temporarily relieves itching & redness caused by pollen, ragweed, grass, animal hair & dander
RELIEF FOR ITCHY EYES: Opcon-A eye drops are clinically proven to help temporarily relieve the redness & itching caused by symptoms of common airborne allergens like ragweed or grass
BAUSCH and LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops
EYE CARE EXPERTS: For over 150 years, Bausch and Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more
EYE DROPS & MORE: Bausch and Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to make sure your eyes feel healthy, moisturized & protected
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Carnie Universal | 9.84 | ✅ | ✅ | ✅ |
Long-lasting relief plus protection
No preservatives
#1 Doctor recommended
100 Vials
For mild to moderate dry eye including lasik dryness
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
For extended wear, frequent replacement, and disposable soft contact lenses
Sterile, isotonic solution
Soothes and moisturizes eyes for greater comfort
100% satisfaction guaranteed
Please read all label information upon delivery
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Preservative free dry-eye treatment
Saturates dry eye
For maximum relief
30 Count
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
#1 Dr Recommended Brand of Artificial Tears*
Thickest gel formulation to coat the eye with a strong layer of dry eye symptom protection.
Provides long-lasting, nighttime protection while you sleep.
For the temporary relief of burning and irritation due to dryness of the eye
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Refresh Plus dose more than just soothe and relieve your eyes.
Refresh Plus dose more than just soothe and relieve your eyes.
The packaging may vary
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Original strength, preservative-free formula
Relieves mild symptoms of eye dryness
Instantly moisturizes and lubricates
Designed to act like your own natural tears
Great for sensitive eyes
Value size! 70 on-the go, single-use vials
Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
The #1 selling brand in preservative-free artificial tears.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Clear Eyes Contact lens multi-action relief eye drops. Use while wearing daily and extended-wear soft contact lenses
These soothing eye drops feature a sterile, buffered solution that refreshes and lubricates eyes for up to 12 hours
Moistens lenses and helps remove particulate matter that can cause irritation and discomfort
Pack of 2
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| ❌ | ❌ | ❌ |
Contains Refresh Optive Mega-3 Lubricant Eye Drops, Preservative-Free (0.01 Fl Oz Single-Use Containers, 30 Count) and Refresh P.M. Lubricant Eye Ointment, Nighttime Relief, Preservative-Free (0.12 Oz Sterile)
Preservative-free moisture-rich formula; Designed to relieve moderate symptoms of eye dryness.
Nighttime relief for intense eye dryness
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
CONTACT LENS FRIENDLY: Biotrue Hydration Boost Eye Drops can be applied while wearing soft contact lenses.
INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.
BIOTRUE EYE DROPS: Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced.
EYE DROPS and MORE: Bausch and Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, and ointments to help your eyes feel moisturized and protected.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
For external use only
May be used as a protectant against further irritation.
For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.
Item Package Dimension: 0.762cm L x 4.572cm W x 8.636cm H
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Argamantic | 9.91 | ✅ | ✅ | ✅ |
Original strength formula
Relieves mild symptoms of eye dryness
Instantly moisturizes and lubricates
Designed to act like your own natural tears
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
0.5-fluid ounce bottle of Visine Dry Eye Relief All Day Comfort Lubricant Dry Eye Drops to moisturize and soothe dry eyes and protect against further irritation
Sterile moisturizing eye drops start working in seconds to provide temporary relief of burning, eye irritation, and discomfort due to dryness of the eye
These eye drops start to relieve dry eye in seconds
From Visine, a brand backed by 60 years of expertise, these eye drops feature the lubricant polyethylene glycol 400 and provide up to 10 hours of comfort
Visine All Day Comfort Dry Eye Relief Eye Drops are available in a small, convenient-to-carry bottle for convenient relief anywhere, even on-the-go
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| OTCRx4u | 9.93 | ❌ | ❌ | ❌ |
HYDROGLOW TECHNOLOGY: Helping to improve the corneal surface of the eye, the technology soothes the eyes leaving them white and clear.
RELIEVING AND SOOTHING: The addition of menthol combines with other ingredients to create a very mild cooling sensation that refreshes the eyes.
MAXIMUM STRENGTH: Our Optic Glow formula offers the maximum strength allowed over the counter to help relieve the redness of the eyes due to dryness.
SYMPTOM RELIEF: Rohto Optic Glow relieves five key symptoms of dry eye, including dryness, irritation, grittiness, burning, and stinging.
HYDRATES THE EYES: The inclusion of dual lubricant active ingredients in our proprietary formula hydrates the eyes and tackles discomfort. ALL (English) Global
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| MA Health | 9.81 | ❌ | ❌ | ❌ |
Package dimensions: 12.954 cms L x 21.844 cms W x 23.876 cms H
Package quantity: 1
Product type: Professional_Healthcare
Country of Origin: United States
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ❌ |
#1 Dr Recommended Brand of Artificial Tears*
Reduces both the signs and symptoms of dry eye
Long Lasting Relief
Soothing comfort; Dry Eye Therapy
Keep your eyes feeling moist and refreshed during your day
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Extended relief plus protection for dry, irritated eyes
Our most comprehensive gel formula
Anytime relief, day or night
Feels like a drop but works like a gel for lasting comfort
Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
Here is the list of top-rated brands that were evaluated by PM.
| Brand | Count |
|---|---|
| Refresh | 10 |
| Clear Eyes | 2 |
| Systane | 2 |
| Bausch & Lomb | 1 |
| Biotrue | 1 |
| Opcon-A | 1 |
| Rohto | 1 |
| Theratears | 1 |
| Visine | 1 |
We've carried out a comprehensive analysis of 100,569 reviews on eye drops refresh plus, using our selection criteria to identify the best options in the categories. Our findings reveal that most customers typically select eye drops refresh plus priced around $15.18, with top brands including refresh, biotrue, similasan, opcon-a, clear eyes, rohto, systane, visine and bausch & lomb and gms optical
Our team of expert editors reviewed these high-quality items and handpicked the top 20 eye drops refresh plus for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the categories category. These include amazon.com and argamantic and group medical supply .
We are dedicated to assisting our users in finding the right drops Products based on their needs, saving them considerable time when choosing which eye drops refresh plus to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.
PickSmartly is dedicated to creating a platform designed to streamline your shopping experience, empowering you to make well-informed purchasing decisions with minimal time and effort. At the heart of our mission is the commitment to earning and maintaining the trust of our users, as we believe this to be fundamental to the services we provide.
When you engage with our websites, services, or tools, we or our approved service providers may utilize cookies to store information. This is done to enhance your user experience by making it more efficient, secure, and tailored to your preferences, as well as for marketing objectives.
We are an Amazon Associate and earn commissions from qualifying purchases. Our participation in the Amazon Services LLC Associates Program, an affiliate advertising initiative, provides us with a means to generate income through links to Amazon.com and its affiliated websites. Please note that Amazon, Amazon Prime, their logos, and the Amazon Prime logo are registered trademarks of Amazon.com, Inc., or its associated companies.
