Best Psychobiotics in 2026

DOCTOR FORMULATED IMMUNE SUPPORT FOR KIDS: Supports immune system and digestive health with 5 billion CFU and 14 probiotic strains, prebiotics and Whole Food vitamins C and D, all in one yummy chewable tablet that is gluten free, dairy free and soy free

GLUTEN-FREE DIGESTION SUPPORT: This 5 Billion CFU once daily probiotic supplement contains Lactobacillus acidophilus, gasseri, paracasei, and plantarum as well as Bifidobacterium (Bifidobacteria) lactis, breve, infantis, and bifidum for digestive health

WHOLE FOOD VITAMINS FOR KIDS: One-a-day Tasty Organic Berry Cherry flavor chewable probiotics for kids contain 30mg of Whole Food Vitamin C from Organic Amla Berry plus 400 IU of Whole Food Vitamin D, for added immune support—with no added sugar

10 PROBIOTIC STRAINS: Offers a balanced spectrum of live organisms consisting of acid-resistant probiotic bacterial strains that are known to naturally colonize the human GI tract

CLINICALLY VALIDATED STRAINS*: Utilizes bacterial strains that have been clinically validated for their support of healthy immune system function.*

HEALTHY INTESTINAL FLORA*: Probiotic bacteria are critical for healthy digestion, helping maintain the integrity of the intestinal lining, support proper intestinal motility, and participate in the detoxification process.*

PROBIOTICS FOR KIDS: From the #1 Pediatrician-Recommended Probiotic Brand, Culturelle Kids helps promote your child’s digestive health, oral care and immune support when taken regularly

PROVEN EFFECTIVE STRAIN: These safe and effective chewables are formulated with 5 billion CFUs of the scientifically proven probiotic Lactobacillus rhamnosus GG to help keep kids healthy

PROBIOTIC POWER: Culturelle Kids is a natural berry-flavored probiotic chewable tablet that works to populate your child’s gastrointestinal microbiome with good bacteria to support healthy digestion and help keep their immune system strong

Extra strength formula for women with researched probiotic strains to support vaginal, digestive, and immune health.* With 10 probiotic strains PLUS prebiotics food for good bacteria, 50 billion live probiotic cultures per serving compared to 30 billion.*

Contains the doctor-preferred probiotic strain for regularity, so you can trust more than just your gut when it comes to your digestive balance.*

Adults take 1 capsule daily. This probiotic supplement for women is a convenient capsule you can take anywhere and everywhere, with no refrigeration required.

WORLD CLASS STRAINS BACKED BY SCIENCE: Probiotics formulated by an expert team: neuroscientists, microbiologists, chemists and researchers, dedicated to health and wellness, with Dr. Preferred Probiotic Strain for Respiratory Health; Package may vary

MORE CLINICALLY STUDIED STRAINS: Renew Life Ultimate Flora Extra Care 30 Billion CFU Probiotic, for men and women, has more clinically studied strains than the leading brand; 2020 Delicious Living Award-Winner in the Digestive Health category

DIGESTIVE AND IMMUNE SUPPORT FOR ADULTS: This probiotic supplement supports digestive and immune health with 30 billion live cultures from 12 different probiotic strains, in a smaller, easier-to-swallow capsule

PROBIOTIC FOR DIGESTIVE HEALTH: Culturelle probiotics are naturally sourced and formulated to keep your digestive system in balance; restocking good bacteria in your gastrointestinal microbiome

PROVEN EFFECTIVE STRAINS: Culturelle Daily Probiotic Gummies for Men & Women are formulated with 2 billion CFUs of good bacteria, these naturally flavored gummies work to restore good bacteria and support digestive & immune health

PROBIOTIC/PREBIOTIC POWER: Your gut microbiome is essential to overall health; The bacteria that live in your gut are linked to digestive health, cognition, mood, & your immune system; Culturelle Daily Probiotic Gummies support a healthy microbiome

Bio-Kult contains 14 probiotic strains to complement the existing gut flora naturally present in a healthy person’s digestive system

Microorganisms present in the intestine, collectively called the gut microbiota, are essential to our health

Includes Lactobacillus acidophilus, Bifidobacterium longum, Bacillus subtilis and 11 more strains (see full probiotic strain list further down this page)

HIGHEST QUALITY PLANT-BASED PROBIOTICS that are naturally fermented for three years with all-natural ingredients and 12 different strains of probiotic bacteria. Not grown in a lab with a single culture medium, Dr. Ohhira’s process simulates the natural production of probiotics. Fruits and vegetables are added seasonally to feed the bacteria which process this prebiotic material resulting, at the end of 3 years, in strong and effective probiotic bacteria and what are called POSTBIOTIC METABOLITES

THE DR. OHHIRA’S ORIGINAL PROBIOTIC CAPSULE contains prebiotics (the fruits and vegetables) with strong and effective probiotic bacteria (12 strains) and POSTBIOTIC METABOLITES that the probiotic bacteria have been producing during three years of fermentation, including vitamins, amino acids, short-chain fatty acids (SCFAs) which are tremendously beneficial molecules containing immune system-enhancing compounds, detoxifying agents and many other beneficial substances for your digestive health.

THE CAPSULE IS CONSTRUCTED TO ENSURE that the contents are delivered to the small intestine and colon. The unique properties of the capsule together with the prebiotics allows the live active probiotic bacteria to stay alive for years at room temperatures, ready to go to work in your gut. This is an expensive way and the best way to create a probiotic supplement. A supplement carefully crafted over 3 years at a price per capsule comparable to inexpensively cultured probiotics.

31 Probiotic Strains: This Multi-Strain Probiotic includes clinically studied Lactobacillus acidophilus, Bifidobacterium, Saccharomyces boulardii, Lactobacillus reuteri, Lactobacillus rhamnosus, Lactobacillus gasseri, casei, Bifidobacterium longum and plantarum to help restore gut health. Contains soil based spore (SBO) like Bacillus subtilis DE111, Bacillus coagulans, and Bacillus clausii.*

Supercharge your Prebiotic and Probiotics: With patented PreforPro Prebiotic Phage technology. It begins working within hours to destabilize and flush harmful bacteria like E. coli. Also contains Vegan Prebiotic Fiber Powder to boost probiotic growth as well as regularity of digestive health. SBO probiotic (spore or soil based probiotic) and prebiotic together may be part of a plan for IBS and leaky gut or SIBO treatment. *

The Smart Way to Protect your Probiotcs - Time Release! Our probiotic supplements use Stomach Acid Resistant capsules. It is a proven to guard probotics from stomach acid. No need for Refrigerated Storage. All strains thrive at human body temps. S boulardii probiotic is the best way to keep your gut healthy for antibiotics use.*

50 Billion CFU Freeze Dried Strains: Bronson Brain + Mood Probiotic 50 Billion CFU Plus Prebiotic provides 16 freeze dried strains for healthy digestion, immune, brain, and positive mood support.* Freeze drying technology enables preservation, stability, and superior quality by allowing many more beneficial bacteria to survive compared to other processes.

L-Theanine, Bacopa & Rhodiola: We aren’t just your average probiotic. Our Brain + Mood Probiotic additionally provides L-Theanine, Bacopa Monniera and Rhodiola Rosea to promote brain health and to help the body cope to the various stresses in daily life.* Our Brain + Mood Probiotic also includes Inulin Prebiotic Fiber to support the growth of good bacteria.*

Highest Quality Formula: Non-GMO, Gluten-Free and Soy-Free tested at our state of the art cGMP Registered New York Facility.

INNOVATION IN PROBIOTIC SCIENCE: InnovixLabs’ Mood Probiotic is a supplement containing a select group of probiotic bacteria that have been studied for their effect on mood and brain function. These bacteria are sometimes called ‘psychobiotics.’*

CLINICALLY STUDIED FOR MOOD HEALTH: New research reveals a connection between gut health and mood. InnovixLabs’ Mood Probiotic is formulated with 2 unique clinically studied strains: Lactobacillus helveticus Rosell-52ND and Bifidobacterium longum Rosell-175.*

CLINICAL RESEARCH: Research has shown that the unique probiotic blend used in InnovixLabs’ Mood Probiotic may help you cope better in stressful situations,* ease digestive discomfort associated with stress,* and support positive mood and emotional wellness.*

50 Billion Colony Forming Units (CFUs) - Floracil50 includes 50 billion CFUs at time of manufacturing so you know you’re getting the ideal amount of probiotics

Extra Strength Probiotic - Floracil50 is all about supporting healthy gut function, digestion, immune system function, and contains Lactobacillus Rhamnosus and Reuteri Strains for hormonal balance

Gut Health Support - Floracil50's encapsulated design ensures that the "good" bacteria make it to the gut to better support gut health and overall function

STRESS LESS WITH THIS SPECIALTY PROBIOTIC –  This proprietary blend of probiotic strains Lactobacillus helveticus Rosell-52 and Bifidobacterium longum Rosell-175 has been linked to a improved stress response—plus, the gastrointestinal support you’d expect from a probiotic.

GUT FEELINGS SHOULD BE GOOD FEELINGS – Believe it or not, digestive health is tied to your mood. This blend of probiotics and clinically studied saffron extract supports a balanced mood and brain health.

BANISH THE BUTTERFLIES FROM YOUR STOMACH – Sometimes, worries can unsettle your stomach. FLORASSIST Mood relieves minor digestive discomfort that can accompany everyday stress.

TARGETED "FEEL GOOD" STRAINS. B. Infantis, B. Breve, B. Longum, B. Bifidum. We loaded this custom formula with the TOP preforming bacterial strains (while keeping it d lactate free and histamine free) to help support mood and the effects of everyday stress*

D-LACTATE FREE & HISTAMINE FREE. 30 Billion CFU with key strains for MOOD and DIGESTION make it a probiotic that helps support healthy digestive, immune, and mood.*

PREBIOTIC GOS. The ONLY prebiotic studied to help with mood support. Prebiotic feeds the good bacteria in your gut for maintaining a healthy microbiome*

THE PERFECT NIGHT TIME SUPPLEMENT: No sleeping pills needed. This ingenious combination of probiotics, digestive enzymes, Melatonin and Chamomile aids gut relief and helps support a peaceful rest. Super smart probiotic supplements for men and women.

FEEL REFRESHED: Groundbreaking probiotic supplement and digestive enzymes support healthy digestion and promote relaxation and sleep. Melatonin assists with getting a good nights sleep. Best natural sleep aids for adults. Wake up feeling great!

NATURAL BOTANICAL BLEND: Non habit forming Melatonin promotes restful sleep and Chamomile has nervine qualities, which can help the body cope with tension. Powerful dual action botanicals provide sleep aid naturally.

GUT HEALTH IS KEY. Your gut microbiome is essential for digestive, respiratory, and immune health. This advanced formula is designed to support all three for whole-body wellbeing.

PREBIOTICS + POSTBIOTICS. Nutrient-dense sprouted flax, amla, moringa, aloe, and chaga mushroom are fermented with L. rhamnonsus GG and B. breve BR03 to deliver a rich source of prebiotics and immune-supporting postbiotics and para-probiotics.

LIVE PROBIOTIC SUPER-STRAIN. Our Lactobacillus plantarum DR7 is an elite live probiotic clinically proven to promote microbiome diversity for gut health, respiratory health, and strengthen the immune response.

6 Targeted Probiotic Strains: Specifically chosen for the benefits they provide to both cognitive and overall health, including supporting mood, memory, focus, immune function, digestion, and regularity. With a patented delivery method, the probiotic organisms in this formula are released over an 8-10 hour period so they bypass your stomach acids and reach deep into your intestinal tract alive (where they are needed most) so you can experience the benefits that probiotics have to offer.*

An Easy Regimen and Convenient: This probiotic formula also contains prebiotics for additional support. Prebiotics are to probiotics what fertilizer is to a garden. There is also 0 refrigeration necessary. With the patented LiveBac manufacturing process, we offer a guaranteed, extended shelf life.*

Formulated For Your Needs: Probiotics combined with excellent ingredients such as Suntheanine (L-theanine) to support a calm and positive emotional state. Gut-Brain Balance also contains 100 mg of FOS to help probiotics colonize and take up residence within your intestinal tract, so they can give you the support you need to stay focused.*

✔ INNOVATION IN PROBIOTIC SCIENCE: InnovixLabs’ Mood Probiotic is a supplement containing a select group of probiotic bacteria that have been studied for their effect on mood and brain function. These bacteria are sometimes called ‘psychobiotics.’*

✔ CLINICALLY STUDIED FOR MOOD HEALTH: New research reveals a connection between gut health and mood. InnovixLabs’ Mood Probiotic is formulated with 2 unique clinically studied strains: Lactobacillus helveticus Rosell-52ND and Bifidobacterium longum Rosell-175.*

✔ 31 PROBIOTIC STRAINS: This Multi-Strain Probiotic includes clinically studied Lactobacillus acidophilus, Bifidobacterium, Saccharomyces boulardii, Lactobacillus reuteri, Lactobacillus rhamnosus, Lactobacillus gasseri, casei, Bifidobacterium longum and plantarum to help restore gut health. Contains soil based spore (SBO) like Bacillus subtilis DE111, Bacillus coagulans, and Bacillus clausii.*

✔ POWERFUL PROBIOTIC - Akkermansia contains 100 million AFU of a patented strain of Akkermansia muciniphila. It is a novel probiotic strain that naturally occurs in the layer of the large intestines and works by protecting and enhancing the gut lining. Studies show that the Akkermansia strain makes up approximately 4% of the intestinal bacteria in healthy people, making it essential for a healthy gut microbiome. Akkermansia increases the levels of these good bacteria in your gut.

✔ HEALTHY GUT - An increased level of the Akkermansia muciniphila strain in the gut results in a stronger intestinal wall, which is important for keeping your digestive system in good shape. This unique strain is called a keystone strain for gut health as it restores, protects, and strengthens the digestive lining. Take 1 capsule daily to help fuel and boost your gut microbiome and eliminate digestive problems.

✔ IMPROVES OVERALL HEALTH - A well-balanced gut microbiome helps with overall health. Higher amounts of Akkermansia muciniphila mean your gut is healthier, so take a probiotic that contains this beneficial bacteria. Pendulum is the only brand on the market with Akkermansia.

WHOLE BODY HEALTH - Morning Complete is a powerful daily wellness drink featuring a custom-selected blend of nutrients designed to support regular digestive function, daily energy levels, and overall wellness.

POWERFUL PREBIOTICS AND PROBIOTICS - Prebiotics are like the fertilizer for your microbiome. Without prebiotics, the probiotic bacteria that your gut relies on for regularity and wellbeing can’t function. Probiotics to replenish and nourish the naturally occuring good bacteria in your gut, for enhanced digestive function and overall health.

NO CRASHES - Energy nutrients from leafy greens — the kind of nutrients your system needs to help you sail through even the busiest days without energy crashes.

✔ INNOVATION IN PROBIOTIC SCIENCE: InnovixLabs’ Mood Probiotic is a supplement containing a select group of probiotic bacteria that have been studied for their effect on mood and brain function. These bacteria are sometimes called ‘psychobiotics.’*

✔ CLINICALLY STUDIED FOR MOOD HEALTH: New research reveals a connection between gut health and mood. InnovixLabs’ Mood Probiotic is formulated with 2 unique clinically studied strains: Lactobacillus helveticus Rosell-52ND and Bifidobacterium longum Rosell-175.*

✔ 🥬 PREBIOTIC FIBER COMPLEX - plant-based prebiotic powder to feed healthy gut bacteria. Supports gut health, digestion, and regularity. The SECRET to a healthy and diverse gut flora is wide variety of prebiotic and fiber.*

✔ INNOVATION IN PROBIOTIC SCIENCE: InnovixLabs’ Mood Probiotic is a supplement containing a select group of probiotic bacteria that have been studied for their effect on mood and brain function. These bacteria are sometimes called ‘psychobiotics.’*

✔ CLINICALLY STUDIED FOR MOOD HEALTH: New research reveals a connection between gut health and mood. InnovixLabs’ Mood Probiotic is formulated with 2 unique clinically studied strains: Lactobacillus helveticus Rosell-52ND and Bifidobacterium longum Rosell-175.*

✔ TRIPLE STRENGTH: InnovixLabs Triple Strength delivers 900 mg of Omega-3 per capsule. You’ll get powerful benefits with fewer pills. Omega Fish Oil 900 is made with premium ingredients and produced to the GOED quality standards. Manufactured in a cGMP certified facility for safety and reliability.