Best Vicks Cough Sore Throat Medicine in 2026
Daisy
Last Updated: Jul 20, 2026
Daisy
Last Updated: Jul 20, 2026
* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Deep Seas Wares | 8.64 | ❌ | ❌ | ❌ |
24-count box of Tylenol Sinus + Headache Daytime Caplets for non-drowsy sinus symptom and headache pain relief due to the common cold, hay fever or other respiratory allergies
Pain reliever and nasal decongestant formulated to temporarily relieve symptoms of nasal congestion, sinus headache and pressure
Each sinus relief caplet contains 325 mg of acetaminophen to temporarily relieve pain and reduce fever as well as 5 mg of phenylephrine HCl, a nasal decongestant to help clear nasal passages
The non-drowsy formula of this sinus medicine provides effective daytime symptom relief by promoting sinus drainage and helping to decongest sinus openings and passages
From the #1 doctor-recommended pain relief brand, these daytime headache and sinus relief caplets are suitable for adults and children ages 12 years and older
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
ALKA-SELTZER PLUS Severe Cold Sparkling Original POWERFAST Fizz EFFERVESCENT Cold Tablets provide fast relief from cold symptoms
Our severe cold, cough formula provides fizzy fast relief of: nasal congestion, sinus pressure & congestion, sneezing, runny nose, headache, fever, sore throat and body aches & pains.
Provides severe cold relief from congestion, coughing, and sore throat
Each box containing 18 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes this cold remedy easy to take with you on the go.
Works as flu and cold relief with acetaminophen as an ingredient
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Spintrex | 7.81 | ❌ | ❌ | ❌ |
Our fantastic formula made even better: improved flavor, less sodium, & aspartame free
Our severe Cold night formula provides unbeatably liquid fast relief of headache, sore throat, cough, nasal congestion, sinus pressure & Congestion, runny nose, sneezing, Aches & pains and fever.
Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.
Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go
Comes in Effervescent form, with a refreshing lemon flavor. Use as directed.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Our fantastic formula made even better: improved flavor, less sodium, & aspartame free
Our severe Cold & Flu medicine formula provides unbeatably fast relief of headache, sore throat, cough, nasal & sinus congestion, runny nose, sneezing, aches & pains and fever.
#1 Cold & Flu effervescent Brand
Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.
Each box containing 24 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| RhinoSystems | 9.92 | ✅ | ✅ | ✅ |
Your NOSE is the body’s AIR FILTER, the first line of defense against airborne particulates. Now you can keep your nose clean with easy-to-use Naväge nasal rinse!
Naväge uses POWERED SUCTION to FLUSH OUT ragweed, pollen, encrusted mucus, and airborne particulates. Naväge is the world’s ONLY nose cleaner with powered suction. You’ll love that clean-nose feeling!
For fast, all-natural relief from allergies and sinus congestion – WITHOUT DRUGS! Naväge operates only with genuine Naväge SaltPod capsules.
Bundle includes Naväge Nose Cleaner, 20 Navage SaltPods inside the box, 1 pair of Standard Nose Pillows, and batteries. $109.95 if purchased separately. You save $10 (9%)!
Make good NASAL hygiene, YOUR new normal. CLEAN NOSE, HEALTHY LIFE!
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| RhinoSystems | 9.92 | ✅ | ✅ | ✅ |
Your NOSE is the body’s Air Filter, your first line of defense against germs and allergens, and it’s why cleaning your nose is the next evolution in Daily Personal Hygiene.
Naväge uses POWERED SUCTION to FLUSH OUT ragweed, pollen, encrusted mucus, and airborne particulates. Naväge is the world’s ONLY nose cleaner with powered suction. You’ll love that clean-nose feeling!
For fast, all-natural relief from allergies and sinus congestion – WITHOUT DRUGS! Naväge operates only with genuine Naväge SaltPod capsules.
Bundle includes Naväge Nose Cleaner, 20 Navage SaltPods inside the box, Countertop Caddy, 1 pair of Standard Nose Pillows, and batteries. The Countertop Caddy is the all-important accessory! It’s the custom-made solution to keep your Naväge clean, dry, and organized for the next use. Plus, it looks great!
The Naväge Nose Cleaner is covered by a one-year parts and labor warranty.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
25% smaller than original liquid gel: Alka seltzer plus cold maximum strength cough, mucus & Congestion Powermax gels have a concentrated formula to provide powerful fast relief
Provides powerful maximum multi-symptom relief from nasal congestion, cough, headache, chest congestion, body ache, sore throat, Sinus pressure & Congestion and fever
Fast cold relief so you can get back to your busy life
Each box containing 24 Liquid gels, 1 dose (2 Liquid gels)
Use as directed
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Coldcalm Tablets address symptoms at every stage of a cold. It temporarily relieves symptoms such as sneezing, runny nose, nasal congestion and minor sore throat.
Coldcalm Tablets do not cause drowsiness and it has no known interactions with other medications.
Recommended for everyone ages 3 and up, and is available in a box of 60 quick-dissolving tablets.
Boiron cough, cold and flu medicines do not cause drowsiness or sleeplessness
At Boiron, we believe there’s more than one way to feel better. Since 1932, the Boiron family has been committed to providing quality medicines. As world leader in homeopathy, our passion is your health. Our promise is your satisfaction.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Our fantastic formula made even better: Improved flavor, less sodium and aspartame free
Our severe Cold and Flu formula provides unbeatably liquid fast relief of headache, sore throat, cough, nasal and sinus congestion, runny nose, sneezing, Aches, pains and fever.
Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.
Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go
Comes in Effervescent form, in a refreshing citrus flavor. Use as directed.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
MAX STRENGTH: Maximum Strength, Multi-Symptom Cold + Flu Relief
SYMPTOM RELIEF: Contac Cold + Flu Day caplets provide symptom relief for Nasal Congestion, Sinus Pressure, Sore Throat, Head & Minor Body Aches, and Fever.
NON-DROWSY: Contac Cold + Flu Day provides multi-symptom relief in a non-drowsy caplet.
CONTAC COLD + FLU: Contains maximum strength active ingredients.
24 Caplets per box.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| MASKU LLC | 9.65 | ✅ | ✅ | ✅ |
ALKA-SELTZER PLUS Severe Non-Drowsy Cold & Cough PowerFast Fizz Effervescent Tablets is a cold remedy for adults, with less sodium, improved flavor, and aspartame free.
Our severe Cold & Cough formula provides unbeatably liquid fast cold relief of headache, sore throat, cough, nasal & sinus congestion, runny nose, sneezing, aches, pains, fever and other severe cold symptoms.
Also acting as a cough suppressor and dry cough medicine, the non-drowsy formula allows individuals to stay alert and productive while battling cold symptoms.
Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes this cold remedy for adults easy to take with you on the go
The cold tablets are designed to dissolve quickly in water, creating a refreshing and effervescent citrus-flavored drink while tackling your severe cold & cough symptoms.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Our fantastic formula made even better: improved flavor, less sodium, and aspartame free
Our severe Cold and Cough medicine formula provides unbeatably liquid fast relief of headache, sore throat, cough, nasal and sinus congestion, runny nose, sneezing, aches and pains and fever
Quickly dissolves in water and instantly ready to start working so you can get back to your busy life
Cold and Flu Effervescent Brand
Each box containing 24 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Umcka Cold+Flu Berry FastActives combine Pelargonium sidoides (EPs 7630) 1X and Alpha CF into one great-tasting, non-drowsy, multi-action cold and flu formula. (1 box of 10 packets each)
Shortens duration and reduces severity of symptoms associated with the common cold and throat/nasal/bronchial irritations, and temporarily relieves flu symptoms.
Cold and flu relief, multi-action formula minor aches/pains, congestion, cough, fever, runny nose, sore throat.
Rapidly melts in mouth - Suitable for children - Non-Drowsy.
Berry flavored powder packets.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Bigfoot Distribution | 9.42 | ✅ | ✅ | ✅ |
Our fantastic formula made even better: improved flavor, less sodium, & aspartame free
Our severe non-drowsy formula provides unbeatably liquid fast relief of sore throat, cough, nasal & sinus congestion, headache, Aches & pains and fever.
Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.
Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go
Comes in Effervescent form, with a refreshing citrus flavor. Use as directed.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Umcka Cold+Flu Berry FastActives combine Pelargonium sidoides (EPs 7630) 1X and Alpha CF into one great-tasting, non-drowsy, multi-action cold and flu formula. (6 boxes of 10 packets each)
Shortens duration and reduces severity of symptoms associated with the common cold and throat/nasal/bronchial irritations, and temporarily relieves flu symptoms.
Cold and flu relief, multi-action formula minor aches/pains, congestion, cough, fever, runny nose, sore throat. These indications are based solely on traditional homeopathic use. They have not been evaluated by the Food & Drug Administration.
Rapidly melts in mouth - Suitable for children - Non-Drowsy.
Berry flavored powder packets.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Vitamins To Go | 9.91 | ✅ | ✅ | ✅ |
Coldcalm Tablets address symptoms at every stage of a cold. It temporarily relieves symptoms such as sneezing, runny nose, nasal congestion and minor sore throat.
Coldcalm Tablets do not cause drowsiness and it has no known interactions with other medications.
Recommended for everyone ages 3 and up, and is available in a box of 60 quick-dissolving tablets.
Boiron cough, cold and flu medicines do not cause drowsiness or sleeplessness.
Coldcalm's natural active ingredients will provide relief for your cold.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Amazon.com | 9.68 | ✅ | ✅ | ✅ |
Throatcalm is a medicine cabinet must-have for every teacher singer or coach. It is recommended for everyone ages 12 & up and is available in a box of 60 quick-dissolving tablets. The quick dissolving tablets ensure there is no additional pain to swallow.
Throatcalm Sore Throat Tablets temporarily relieve minor red, dry, and sore throat and hoarseness. Throatcalm does not cause drowsiness and it has no known interactions with other medications. Throatcalm is not contraindicated with pre-existing conditions.
Adults and children 12 years and older: At the onset of symptoms, dissolve 2 tablets under the tongue every 15 minutes for 1 hour. Then, dissolve 2 tablets under the tongue 3 times a day until symptoms are relieved. For children under 12: consult a doctor.
Our mission is to stimulate the evolution of health care by promoting homeopathy as a compassionate, ecological and comprehensive approach to medicine. At Boiron, we believe there’s more than one way to feel better. Our promise is your satisfaction.
Active ingredients: arnica montana 3C HPUS, arum triphyllum 3C HPUS, Belladonna 3C HPUS, Bromium 3C HPUS, Bryonia 3C HPUS, Mercurius solubilis 4C HPUS, Phytolacca decandra 3C HPUS, Pulsatilla 3C HPUS, Spongia tosta 3C HPUS. Contains Lactose
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| BIGZI | 6.13 | ❌ | ❌ | ❌ |
Two 8 ounce bottles
Cherry flavored
No added colors
Pack of two, 8-ounce boxes (total of 16 ounces)
Alcohol-free
Provides relief from allergies for children
Works well against severe cold and cough, pain relief, nasal congestion, cough, runny nose, sneezing, sore throat
Cherry flavor
Pack of two, 8-ounce boxes (total of 16 ounces)
Alcohol-free
Provides relief from allergies for children
Works well against severe cold and cough, pain relief, nasal congestion, cough, runny nose, sneezing, sore throat
Cherry flavor
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| Royal Meds | 9.95 | ❌ | ❌ | ❌ |
Children's Coldcalm Pellets addresse symptoms at every stage of a cold. It temporarily relieves symptoms such as sneezing, runny nose, nasal congestion and minor sore throat.
Children's Coldcalm Pellets do not cause drowsiness and it has no known interactions with other medications.
Recommended for everyone ages 3 and up, and is available in a box of 60 quick-dissolving tablets.
Boiron cough, cold and flu medicines do not cause drowsiness or sleeplessness
At Boiron, we believe there's more than one way to feel better. Since 1932, the Boiron family has been committed to providing quality medicines. As world leader in homeopathy, our passion is your health. Our promise is your satisfaction.
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| RhinoSystems | 9.92 | ✅ | ✅ | ✅ |
Your NOSE is the body’s AIR FILTER, the first line of defense against airborne germs and allergens. Now you can keep your nose clean with easy-to-use Naväge nasal rinse!
Naväge uses POWERED SUCTION to FLUSH OUT allergens, germs, dirt, and mucus. Naväge is the world’s ONLY nose cleaner with powered suction. You’ll love that clean-nose feeling!
Naväge operates only with genuine Naväge SaltPod capsules. Make good nasal hygiene, your new normal. CLEAN NOSE, HEALTHY LIFE!
Bundle includes Naväge Nose Cleaner, 20 Navage SaltPods inside the box, 2nd Nasal Dock, 2nd Pair of Nose Pillows, and batteries. $114.95 if purchased separately. You save $9.95 (9%)!
Make good NASAL hygiene, YOUR new normal. CLEAN NOSE, HEALTHY LIFE!
| SELLER | SELLER SCORE | AMAZON FULFILLED | PRIME | FREE SHIPPING |
|---|---|---|---|---|
| ❌ | ❌ | ❌ |
ALKA-SELTZER PLUS Severe Cold Day Night Medicine is a powerful cold and flu medicine designed specifically for adults and children 12 years and older.
Our Severe Day and Night cold and flu medicine provides fizzy fast daytime relief of nasal & sinus congestion, cough, headache, fever, sore throat and body aches & pains. Provides nighttime cold relief of: nasal congestion, sinus pressure & congestion, sneezing, runny nose, cough, headache, fever, sore throat and body aches & pains.
This cold and flu medicine for adults and children 12 years and older quickly dissolves in water and instantly ready to start working so you can get back to your busy life
Each flu & cold relief box has 24 Sachets each containing 1 individually wrapped dose (2 effervescent cold tablets), which makes it easy to take with you on the go
Each cold and flu medicine tablet comes in Effervescent form. Use as directed.
Packaging may vary
Here is the list of top-rated brands that were evaluated by PM.
| Brand | Count |
|---|---|
| Alka-Seltzer Plus | 9 |
| Boiron | 4 |
| Navage | 3 |
| Nature's Way | 2 |
| Benadryl | 1 |
| Contac | 1 |
| Tylenol | 1 |
We've carried out a comprehensive analysis of 78,525 reviews on cough sore throat medicine, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select cough sore throat medicine priced around $31.04, with top brands including mucinex, boiron, chloraseptic, vicks, theraflu, alka-seltzer plus, robitussin, hyland's and sucrets and ricola
Our team of expert editors reviewed these high-quality items and handpicked the top 21 cough sore throat medicine for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, nc commercial, greatprices4u, bnt distributor, incredible designs llc, name brand overstock, healthy products a plus llc, the customer land and beekeeper's naturals and focus health .
We are dedicated to assisting our users in finding the right medicine Products based on their needs, saving them considerable time when choosing which cough sore throat medicine to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.
PickSmartly is dedicated to creating a platform designed to streamline your shopping experience, empowering you to make well-informed purchasing decisions with minimal time and effort. At the heart of our mission is the commitment to earning and maintaining the trust of our users, as we believe this to be fundamental to the services we provide.
When you engage with our websites, services, or tools, we or our approved service providers may utilize cookies to store information. This is done to enhance your user experience by making it more efficient, secure, and tailored to your preferences, as well as for marketing objectives.
We are an Amazon Associate and earn commissions from qualifying purchases. Our participation in the Amazon Services LLC Associates Program, an affiliate advertising initiative, provides us with a means to generate income through links to Amazon.com and its affiliated websites. Please note that Amazon, Amazon Prime, their logos, and the Amazon Prime logo are registered trademarks of Amazon.com, Inc., or its associated companies.
