Best Vicks Cough Sore Throat Medicine in 2026

Daisy
Last Updated: Jul 20, 2026

At a Glance: Our Top Picks for Vicks Cough Sore Throat Medicine

Mucinex Fast-Max Maximum Strength Cold & Flu Day and Night Medicine, All-in-One Multi-Symptom Relief Liquid Gels – 24 count (16 Day time + 8 Night time) (Packaging May Vary)
#TOP1
Mucinex Fast-Max Maximum Strength Cold & Flu Day
9.9
PM SCORE
Alka-Seltzer Plus Maximum Strength Cough, Mucus & Congestion Powermax Liquid Gels, 24 Count
#TOP2
Alka-Seltzer Plus Maximum Strength Cough, Mucus & Congestion
9.8
PM SCORE
Alka-seltzer Plus Cold & Flu, Power Max Cold and Flu Medicine, Night, For Adults with Pain Reliever, Fever Reducer, Cough Suppressant, Nasal Decongestant, Antihistamine, 36 Count
#TOP3
Alka-Seltzer Plus Cold & Flu, Power Max Cold
9.8
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Vicks Cough Sore Throat Medicine of 2026

Mucinex Fast-Max Maximum Strength Cold & Flu Day And Night Medicine, All-In-One Multi-Symptom Relief Liquid Gels – 24 Count (16 Day Time + 8 Night Time) (Packaging May Vary)

MUCINEX
371505
1.73 X 3.54 X 4.92 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Stam Sales 9.93

Features

MAXIMUM STRENGTH MUCINEX FAST-MAX COLD & FLU: Multi-Symptom Relief medicine; 1 dose treats 9 symptoms - get back to what’s important thanks to the fast, powerful medicine

DAY TIME MULTI-SYMPTOM RELIEF: Maximum Strength Day Time Cold and Flu helps reduce fever, relieve cough, chest, nasal & sinus congestion that can cause mucus buildup, sinus pressure, minor aches and pains, headache and sore throat

NIGHT TIME MULTI-SYMPTOM RELIEF: Maximum Strength Night Time Cold and Flu helps reduce fever, relieve cough, nasal congestion that leads to stuffy nose, minor aches and pains, headache, sneezing, runny nose and sore and itchy throat

# 1 TRUSTED COLD & COUGH BRAND: #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand**

DAY TIME ACTIVE INGREDIENTS PER LIQUID GEL: Contains Acetaminophen - Pain reliever and Fever reducer; Dextromethorphan HBr - Cough Suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal Decongestant

NIGHT TIME ACTIVE INGREDIENTS PER LIQUID GEL: Contains Acetaminophen - Pain reliever/Fever reducer; Dextromethorphan HBr - Cough suppressant; Doxylamine succinate - Antihistamine; Phenylephrine HCI - Nasal Decongestant

Alka-Seltzer Plus Maximum Strength Cough, Mucus & Congestion Powermax Liquid Gels, 24 Count

ALKA-SELTZER PLUS
3.50 X 1.50 X 5.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

25% smaller than original liquid gel: Alka seltzer plus cold maximum strength cough, mucus & Congestion Powermax gels have a concentrated formula to provide powerful fast relief

Provides powerful maximum multi-symptom relief from nasal congestion, cough, headache, chest congestion, body ache, sore throat, Sinus pressure & Congestion and fever

Fast cold relief so you can get back to your busy life

Each box containing 24 Liquid gels, 1 dose (2 Liquid gels)

Use as directed

Alka-Seltzer Plus Cold & Flu, Power Max Cold And Flu Medicine, Night, For Adults With Pain Reliever, Fever Reducer, Cough Suppressant, Nasal Decongestant, Antihistamine, 36 Count

ALKA-SELTZER PLUS
3.50 X 1.50 X 5.00 Inches
0.19 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

25% smaller pill: Alka-Seltzer Plus Maximum Strength cold & Flu Powermax gels have a concentrated formula to provide powerful fast relief

Maximum strength day time and night time relief from your worst cold & Flu symptoms

Day time multi-symptom relief of nasal congestion, cough, headache, body ache, sore throat, Sinus pressure and fever. Night time multi-symptom relief of runny nose, nasal congestion, cough, headache, body ache, sore throat and fever.

Fast relief so you can get back to your busy life

Use as directed.

Alka-Seltzer Plus Cold & Flu, Power Max Cold And Flu Medicine, Day, For Adults With Pain Reliver/Fever Reducer, Cough Suppressant, Nasal Decongestant, 24 Count

ALKA-SELTZER PLUS
I00104723
3.50 X 1.50 X 0.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Hammond K&T 9.12

Features

NEW 25 percent smaller pill: Alka Seltzer Plus Maximum Strength Cold & Flu PowerMax Gels have a concentrated formula in a smaller liquid gel so it's easier to swallow

Provides up to 4 hours of relief: one dose provides 4 hour day time relief of cough, nasal congestion, headache & body ache, sore throat, and sinus pressure

Alka Seltzer Plus Maximum Strength Cold & Flu PowerMax Gels contain a pain reliever, fever reducer, cough suppressant, and nasal decongestant

Temporarily relieves these symptoms due to a cold or flu: Minor aches and pains, cough, headache, sore throat, & nasal and sinus congestion. Temporarily reduces fever

PowerMax Gels do not have to be taken with meals

Valumeds Nighttime Cough Plus Cold And Flu Relief Medicine | 48 Pack Softgel Liquid Capsules | Helps Relieve Sore Throat, Fever, Headaches, Runny Nose, Aches

VALUMEDS
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
ValuMeds 9.90

Features

Powerful Nighttime Relief: ValuMeds Nighttime Cough Plus Cold and Flu Relief Medicine is specifically formulated to provide effective relief from cough, cold, and flu symptoms during the night. Say goodbye to sleepless nights and wake up feeling refreshed.

Comprehensive Cold and Flu Relief: Our medicine combines the power of a cough suppressant, cold, and flu relief to provide you with comprehensive symptom relief. From coughing and congestion to sore throat and sinus pressure, our formula targets multiple symptoms to help you feel better.

Trusted Brand for Adults: Trust in our brand's expertise in cold and flu relief. Our Nighttime Cough Plus Cold and Flu Relief Medicine is suitable for adults and is comparable to leading brands like Nyquil and Dayquil. Experience the same quality and effectiveness at a more affordable price.

Convenient Pack: Our pack contains all the necessary doses to get you through the night. Each pack includes the perfect combination of nighttime relief and sleep aid to ensure you get the restful sleep you need to recover from cold and flu symptoms.

Use as Directed: ValuMeds Nighttime Cold and Flu gels should always be used as directed. Please read package for more details on proper use and dosage for children and adults.

Mucinex Maximum Strength Fast-Max Cold & Flu All-In-One Liquid Gels, 16Ct (Packaging May Vary) (Pack Of 2)

MUCINEX
I00104710
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

The below information is per pack only

MAXIMUM STRENGTH RELIEF: Maximum Strength Mucinex Fast-Max Cold & Flu All In One helps reduce fever and relieve cough, sore throat, stuffy nose, chest & nasal congestion, headache and minor aches and pains

#1 TRUSTED COLD & COUGH BRAND: #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand

PAIN RELIEVER: Contains Acetaminophen which reduces fever and relieves minor aches and pains thereby relieving your sore throat pain

COUGH SUPPRESSANT: Contains Dextromethorphan HBr that helps relieve cough

EXPECTORANT: Contains Guaifenesin that thins and loosens mucus; relieves chest congestion

NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure

USAGE: Use as directed; For ages 12+ years

Maximum Strength Mucinex Fast-Max Cold, Flu, & Sore Throat Liquid Gels, 16Ct, Controls Cough, Thins & Loosens Mucus, Relieves Nasal & Chest Congestion, Headache & Fever

MUCINEX
379131
3.54 X 1.06 X 0.00 Inches
0.10 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
BNT DISTRIBUTOR 7.38

Features

MAXIMUM STRENGTH RELIEF: Maximum Strength Mucinex Fast-Max Cold, Flu & Sore Throat helps reduce fever, relieve cough, sore throat, stuffy nose, chest & nasal congestion, headache and minor aches and pains

#1 TRUSTED COUGH & COLD: #1 Cough & Cold Brand Doctors Trust* and #1 Pharmacist Recommended Brand

PAIN RELIEVER: Contains Acetaminophen which reduces fever and relieves minor aches and pains thereby relieving your sore throat pain

COUGH SUPPRESSANT: Contains Dextromethorphan HBr that helps relieve cough

EXPECTORANT: Contains Guaifenesin that thins and loosens mucus; relieves chest congestion

NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure

USAGE: Use as directed; For ages 12+ years

Cold-Eeze Plus Defense Natural Citrus & Elderberry Zinc Chewable Gels, Homeopathic Cold Remedy, Shortens Common Cold Symptoms, Promotes Immune Health With Sambucus Nigra, Echinacea & Rose Hips, 25 Ct

COLD-EEZE
B07XH4T7GJ
2.50 X 2.50 X 3.60 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
JAJ23 5.55

Features

SHORTENS YOUR COLD: Cold-EEZE Plus Defense Chewable Gels, Citrus with Elderberry flavor, formulated with zinc gluconate, rose hips and echinacea, shorten your cold and promote immune health.*

PROMOTES IMMUNE HEALTH: Homeopathic Cold-EEZE Plus Defense Chewable Gels offer cold shortening with the active ingredient zinc and immune health support with active ingredients Rose Hips and Echinacea.*

REDUCES THE SEVERITY OF COLD SYMPTOMS: Cold-EEZE Plus Defense Chewable Gels reduce the severity of cold symptoms including cough, sore throat, nasal congestion, post nasal drip and hoarseness.

NATURALLY FLAVORED: Cold-EEZE Plus Defense Chewable Gels, Citrus with Elderberry, are naturally flavored!

COLD-EEZE: Take Cold-EEZE Plus Defense Chewable Gels, Citrus with Elderberry flavor, the next time you feel a cold coming on and get well faster. 25 chewable gels per bottle.

Mucinex Fast-Max Maximum Strength Cold & Flu All In One, Multi-Symptom Relief, Pain Reliever, Fever Reducer, Cough Suppressant, Expectorant, Nasal Decongestant, 16 Liquid Gels (Pack Of 2)

MUCINEX
363824595160-2PK
1.06 X 3.54 X 4.92 Inches
0.10 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Pattern Products 9.95

Features

Cold and flu relief, 1 Dose, 9 Symptom Relief

Max Strength Day & Night Formula

Fast dissolving liquid gels

Relieves Aches and Pain, Fever, Sore Throat, Sinus Pressure, Nasal & Chest Congestion, Sinus Congestion, and Controls Cough

Multi symptom cold relief

Coricidin Hbp, Decongestant-Free Cold Symptom Relief For People With High Blood Pressure, Maximum Strength Cold & Flu Day+Night Liquid Gels, 24 Count

CORICIDIN HBP
3.50 X 1.06 X 5.00 inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

The #1 doctor recommended brand that gives fast powerful cold symptom relief that's specially designed for people with high blood pressure*.

Powerful cold brand with maximum strength formula for people with high blood pressure*

Provides daytime relief of sore throat, chest congestion, fever, body aches & pains, and headache.

Provides nighttime relief of sore throat, cough, fever, runny nose, sneezing, body aches & pains, and headache

Comes in a concentrated liquid gel form

Mucinex Maximum Strength Fast-Max Cold, Flu, & Sore Throat Liquid Gels, 16Ct, Controls Cough, Thins & Loosens Mucus, Relieves Nasal & Chest Congestion, Headache & Fever (Pack Of 3)

MUCINEX
379131
0.30 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

The below information is per pack only

MAXIMUM STRENGTH RELIEF: Maximum Strength Mucinex Fast-Max Cold, Flu & Sore Throat helps reduce fever, relieve cough, sore throat, stuffy nose, chest & nasal congestion, headache and minor aches and pains

#1 TRUSTED COUGH & COLD: #1 Cough & Cold Brand Doctors Trust* and #1 Pharmacist Recommended Brand

PAIN RELIEVER: Contains Acetaminophen which reduces fever and relieves minor aches and pains thereby relieving your sore throat pain

COUGH SUPPRESSANT: Contains Dextromethorphan HBr that helps relieve cough

EXPECTORANT: Contains Guaifenesin that thins and loosens mucus; relieves chest congestion

NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure

USAGE: Use as directed; For ages 12+ years

Top 10 cough sore throat medicine Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Mucinex 5
Alka-Seltzer Plus 3
Cold-Eeze 1
Coricidin Hbp 1
Valumeds 1

Top 10 cough sore throat medicine Brands Pie Chart


We've carried out a comprehensive analysis of 12,078 reviews on cough sore throat medicine, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select cough sore throat medicine priced around $18.62, with top brands including mucinex, boiron, chloraseptic, vicks, theraflu, alka-seltzer plus, robitussin, hyland's and sucrets and ricola

Our team of expert editors reviewed these high-quality items and handpicked the top 11 cough sore throat medicine for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, nc commercial, greatprices4u, bnt distributor, incredible designs llc, name brand overstock, healthy products a plus llc, the customer land and beekeeper's naturals and focus health .

We are dedicated to assisting our users in finding the right medicine Products based on their needs, saving them considerable time when choosing which cough sore throat medicine to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.