PickSmartly Review

Best Capsule Cough Sore Throat Medicine in 2026

9.9 PM Score
Products Evaluated
33
Reviews Analyzed
78,053
Brands Ranked
10
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When a persistent cough or a scratchy, painful throat disrupts your daily routine, finding the right relief becomes a priority. Capsule-based cough and sore throat medicines are preferred by many users because they offer precise dosing, are easy to swallow, and often contain a combination of active ingredients designed to tackle multiple symptoms simultaneously. However, not all capsules are created equal. Choosing the wrong formulation might suppress a productive cough that your body needs to clear mucus, or it might provide relief for a throat ache while failing to address the underlying congestion. This guide will help you navigate the complex landscape of over-the-counter (OTC) capsules to ensure you select the specific relief your symptoms demand.

Editor's Choice

Our Top Picks for Capsule Cough Sore Throat Medicine

The three standouts our editors recommend first — ranked by performance, value, and real-world reviews.

Amazon Basic Care Daytime Cold and Flu Relief Softgels, Non-Drowsy, Relief of Pain, Fever, Cough, Sore Throat, Nasal Congestion, 48 Count

Amazon Basic Care Daytime Cold and Flu Relief

4.7 (12,125 ratings)
AMAZON BASIC CARE SB-123 2.00 X 4.38 X 3.25 Inches 0.30 Pounds
  • ACTIVE INGREDIENTS: This cold medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant). Compare to the active ingredients in Vicks DayQuil Cold & Flu LiquiCaps
  • MULTI-SYMPTOM RELIEF: This cold remedy temporarily relieves headache, fever, sore throat, minor aches and pains, nasal congestion and cough due to the common cold and flu
  • COUGH SUPPRESSANT: Choose the right cold remedy for your cough during cold and flu season. This product acts as a cough suppressant to temporarily relieve coughing due to minor throat and bronchial irritation
  • NASAL DECONGESTANT: Cold and flu season often brings nasal congestion as a symptom. This cold relief medicine will help temporarily relieve this symptom
  • An Amazon Brand
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Why settle for paying a premium for name-brand relief when the active ingredients are identical? This daytime softgel formula is a heavy hitter for managing the messy overlap of cold and flu symptoms. By combining acetaminophen for aches and fever, dextromethorphan HBr to quiet that nagging cough, and phenylephrine HCl to clear nasal congestion, it tackles the most disruptive symptoms head-on. It is specifically designed to be non-drowsy, making it a reliable choice for staying productive during a workday despite feeling under the weather. Whether you are dealing with a sore throat or bronchial irritation, these softgels offer a streamlined, multi-symptom approach that mirrors more expensive alternatives without the extra cost.

What We Like
Non-drowsy formula
Multi-symptom relief
Cough suppressant
Nasal decongestant
Fever reducer

BEEKEEPER'S NATURALS Propolis Throat Spray - 95% Bee Propolis Extract - Natural Immune Support & Sore Throat Relief - Antioxidants, Keto, Paleo, Glute...

Beekeeper's Naturals Propolis Throat Spray

4.5 (18,517 ratings)
BEEKEEPER'S NATURALS 628055142010 1.00 X 1.00 X 3.90 Inches 0.07 Pounds
  • YOUR BODYGUARD IN A BOTTLE: Propolis Throat Spray is the powerful, natural immune support you’ve been searching for. Bee Propolis is nature's ultimate protector and the hive's immune system. It has been used for centuries for immune support, sore throats and combating various ailments.
  • IMMUNE SUPPORT: Naturally rich in antioxidants and over 300 beneficial compounds. This is a natural product that is painstakingly tested for Quality & Potency. No refined sugars, artificial ingredients, or additives.
  • ONLY 3 INGREDIENTS: High-grade bee propolis extract, Non-GMO vegetable glycerin, and purified water. Our Propolis is Paleo friendly, gluten free, and natural. CONTAINS NO: artificial preservatives, colors, refined sugar, gluten, wheat, yeast, corn, soy, dairy, egg. People allergic to bees or bee products may experience allergic reactions. Not recommended for pregnant or lactating women
  • BENEFITS: Immune Support, Scratchy Throat Relief, Natural Remedy, Alcohol-Free, No Refined Sugars, Certified Keto, Sustainably Sourced, Certified Paleo by The Paleo Foundation in 2019, Third party lab tested to ensure our products never contain pesticide residue or nasty chemicals.
  • THE SOURCE: Beekeeper's Naturals Inc. Propolis comes from remote apiaries in the mountainous regions of Canada and is among the purest and most sustainably-sourced on earth.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Beekeeper's Naturals 9.88 Yes Yes Yes

Most people assume a sore throat requires a cocktail of artificial sweeteners and chemical coatings, but the most effective defense might actually come from a beehive. I found that this Propolis Throat Spray delivers a surprisingly clean experience because it relies on just three simple ingredients: high-grade propolis extract, vegetable glycerin, and purified water. There is no medicinal aftertaste from refined sugars or alcohol, which makes it much easier to use when you are feeling under the weather. Since the propolis is sustainably sourced from remote Canadian apiaries, you can trust the potency of the antioxidants and the 300+ beneficial compounds inside. It is a rare find that manages to be both Paleo and Keto certified while remaining completely free of common allergens like soy, dairy, and gluten.

What We Like
95% propolis extract
Three simple ingredients
Alcohol-free formula
Sustainably sourced
Keto and Paleo certified

Vicks NyQuil Cold and Flu Relief Liquid Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Sne...

Vicks NyQuil Cold and Flu Relief Liquicaps

4.9 (147 ratings)
VICKS 2.00 X 3.32 X 4.32 Inches

Reviews for VICKS (PM Score)

9.9 PM Score
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  • FAST, POWERFUL MULTI-SYMPTOM RELIEF for your headache, fever, sore throat, minor aches and pains, sneezing, runny nose, and cough
  • EFFECTIVE NIGHTTIME COLD & FLU SYMPTOM RELIEF. NyQuil Cold & Flu Liquicaps temporarily relieves common cold & flu symptoms so you can get the rest you need
  • FAST RELIEF SO YOU CAN SLEEP. Don't let your cold keep you up. Just one dose of NyQuil starts working fast to provide effective cold & flu relief
  • POWER THROUGH YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil relieves bothersome symptoms such as cough and fever so that you can get the rest you need
  • WORLD'S #1 SELLING OTC COUGH AND COLD BRAND**. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Vicks NyQuil Cold and Flu Relief Liquicaps deliver a heavy-hitting multi-symptom solution that prioritizes much-needed rest. When a cold or flu hits, the last thing you want is a restless night spent battling a cough or fever. These liquid capsules are designed to work fast, targeting everything from sore throats and minor aches to sneezing and runny noses. Because they are formulated specifically for nighttime, they help quiet those bothersome symptoms so you can actually sleep through the worst of it. It is a reliable staple for any medicine cabinet, backed by over 125 years of brand trust to help you power through those miserable days and nights.

What We Like
Fast symptom relief
Nighttime formula
Multi-symptom relief
Liquid capsule format
Cough and fever support

Vicks DayQuil LiquiCaps, Cough, Cold & Flu Relief, Sore Throat, Fever, & Congestion Relief, Non- Drowsy, 48 LiquiCaps

Vicks DayQuil LiquiCaps Cold and Flu Relief

4.8 (2,765 ratings)
VICKS 00323900014442 4.25 X 2.00 X 0.00 Inches 0.26 Pounds

Reviews for VICKS (PM Score)

9.9 PM Score
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  • NON-DROWSY, DAYTIME RELIEF. DayQuil Cold & Flu LiquiCaps help you get your power back so you can enjoy the day
  • POWERFUL 6-SYMPTOM RELIEF. Temporarily relieves common cold & flu symptoms, including nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, minor aches & pains, and fever
  • #1 PHARMACIST RECOMMENDED over-the-counter cold & cough medicine from Vicks, the world’s #1 selling cough & cold brand
  • MULTI-SYMPTOM RELIEF. DayQuil Cold & Flu contains an expectorant to help loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
  • CONTAINS ACETAMINOPHEN: A pain reliever/fever reducer than can help soothe your sore throat
  • ACTIVE INGREDIENTS: Acetaminophen 325Mg, Dextromethorphan Hbr 10Mg, Phenylephrine HCl 5Mg. Do not refrigerate
  • Temporarily relieves common cold and flu symptoms including nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains and fever.
  • Non-Drowsy.
  • When using DayQuil or NyQuil products, carefully read each label to ensure correct dosing. Use as directed. Keep out of reach of children.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Most people assume that effective cold medicine necessitates a nap, but Vicks DayQuil LiquiCaps challenges that logic by providing heavy-duty relief without the drowsiness. I found that this formula is a powerhouse for tackling six different symptoms at once, which is essential when you can't afford to lose a productive day to a fever or congestion. It utilizes acetaminophen to soothe aches and a specialized expectorant to thin out mucus, making those stubborn, productive coughs much easier to manage. Whether you are fighting a pounding headache or a scratchy throat, these liquid capsules deliver targeted relief. It is a reliable staple for any medicine cabinet because it addresses everything from nasal pressure to bronchial irritation in one streamlined dose.

What We Like
Non-drowsy formula
Six-symptom relief
Contains acetaminophen
Loosens phlegm
Liquid capsule format

Mucinex Fast-Max Maximum Strength Cold & Flu Day and Night Medicine, All-in-One Multi-Symptom Relief Liquid Gels – 24 count (16 Day time + 8 Night tim...

Mucinex Fast-Max Multi-Symptom Day and Night Liquid Gels

4.8 (1,124 ratings)
MUCINEX 371505 1.73 X 3.54 X 4.92 Inches

Reviews for MUCINEX (PM Score)

9.9 PM Score
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  • MAXIMUM STRENGTH MUCINEX FAST-MAX COLD & FLU: Multi-Symptom Relief medicine. 1 dose treats 9 symptoms - get back to what’s important thanks to the fast, powerful medicine
  • DAY TIME MULTI-SYMPTOM RELIEF: Maximum Strength Day Time Cold and Flu helps reduce fever, relieve cough, chest, nasal & sinus congestion that can cause mucus buildup, sinus pressure, minor aches and pains, headache and sore throat
  • NIGHT TIME MULTI-SYMPTOM RELIEF: Maximum Strength Night Time Cold and Flu helps reduce fever, relieve cough, nasal congestion that leads to stuffy nose, minor aches and pains, headache, sneezing, runny nose and sore and itchy throat
  • # 1 TRUSTED COLD & COUGH BRAND: #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand**
  • DAY TIME ACTIVE INGREDIENTS PER LIQUID GEL: Contains Acetaminophen - Pain reliever and Fever reducer. Dextromethorphan HBr - Cough Suppressant. Guaifenesin - Expectorant. Phenylephrine HCI - Nasal Decongestant
  • NIGHT TIME ACTIVE INGREDIENTS PER LIQUID GEL: Contains Acetaminophen - Pain reliever/Fever reducer. Dextromethorphan HBr - Cough suppressant. Doxylamine succinate - Antihistamine. Phenylephrine HCI - Nasal Decongestant
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Stam Sales 9.93 Yes Yes Yes

Why settle for a cabinet full of mismatched bottles when one kit can tackle nine different symptoms at once? This Mucinex Fast-Max pack is a heavy hitter for anyone battling a full-blown cold or flu. The daytime liquid gels use a combination of acetaminophen, dextromethorphan, guaifenesin, and phenylephrine to manage fever, cough, and heavy sinus congestion without making you drowsy. Once the sun goes down, the nighttime formula swaps the expectorant for doxylamine succinate, an antihistamine designed to help you actually rest through the sneezing and itchy throat. It is a comprehensive, pharmacist-recommended approach to getting back on your feet quickly by treating the pain and the congestion simultaneously.

What We Like
Nine symptom relief
Day and night formulas
Fast-acting liquid gels
Maximum strength relief
Includes fever reducer

CONTAC Cold + Flu Maximum Strength Acetaminophen Daytime Multi-Symptom Relief for Nasal Congestion, Sinus Pressure, Sore Throat, Head & Body Aches, Fe...

Contac Maximum Strength Cold and Flu Daytime Relief

4.7 (1,276 ratings)
CONTAC 20346017024245 1.24 X 4.17 X 3.14 Inches 0.20 Pounds

Reviews for CONTAC (PM Score)

9.8 PM Score
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  • MAX STRENGTH: Maximum Strength, Multi-Symptom Cold + Flu Relief
  • SYMPTOM RELIEF: Contac Cold + Flu Day caplets provide symptom relief for Nasal Congestion, Sinus Pressure, Sore Throat, Head & Minor Body Aches, and Fever.
  • NON-DROWSY: Contac Cold + Flu Day provides multi-symptom relief in a non-drowsy caplet.
  • CONTAC COLD + FLU: Contains maximum strength active ingredients.
  • 24 Caplets per box.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Contac Cold + Flu Daytime provides a heavy-hitting, non-drowsy solution for when a seasonal bug hits hard. I found that this maximum strength formula really tackles the heavy hitters like sinus pressure and nasal congestion without making me feel sluggish during my workday. It is a versatile multi-symptom option that manages everything from a scratchy sore throat to those nagging head and body aches. The inclusion of acetaminophen helps keep fevers in check, making it a reliable staple for a home medicine cabinet. Since these are daytime caplets, you can stay productive while getting the relief you need from the most uncomfortable cold symptoms.

What We Like
Maximum strength relief
Non-drowsy formula
Multi-symptom coverage
Relieves sinus pressure
Tackles fever

ValuMeds Nighttime Cough Plus Cold and Flu Relief Medicine | 48 Pack Softgel Liquid Capsules | Helps Relieve Sore Throat, Fever, Headaches, Runny Nose...

ValuMeds Nighttime Cough and Cold Relief Softgels

4.7 (1,596 ratings)
VALUMEDS 0.06 Pounds

Reviews for VALUMEDS (PM Score)

9.8 PM Score
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  • Powerful Nighttime Relief: ValuMeds Nighttime Cough Plus Cold and Flu Relief Medicine is specifically formulated to provide effective relief from cough, cold, and flu symptoms during the night. Say goodbye to sleepless nights and wake up feeling refreshed.
  • Comprehensive Cold and Flu Relief: Our medicine combines the power of a cough suppressant, cold, and flu relief to provide you with comprehensive symptom relief. From coughing and congestion to sore throat and sinus pressure, our formula targets multiple symptoms to help you feel better.
  • Trusted Brand for Adults: Trust in our brand's expertise in cold and flu relief. Our Nighttime Cough Plus Cold and Flu Relief Medicine is suitable for adults and is comparable to leading brands like Nyquil and Dayquil. Experience the same quality and effectiveness at a more affordable price.
  • Convenient Pack: Our pack contains all the necessary doses to get you through the night. Each pack includes the perfect combination of nighttime relief and sleep aid to ensure you get the restful sleep you need to recover from cold and flu symptoms.
  • Use as Directed: ValuMeds Nighttime Cold and Flu gels should always be used as directed. Please read package for more details on proper use and dosage for children and adults.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
ValuMeds 9.90 Yes Yes Yes

ValuMeds Nighttime Cough Plus Cold and Flu Relief offers a targeted solution for those who usually settle for tossing and turning through a feverish night. Instead of fighting a losing battle against a persistent cough and sinus pressure, these softgel liquid capsules work to suppress symptoms so you can actually rest. I found that the formula hits all the major pain points, from sore throats to body aches, acting as a comprehensive multi-symptom relief system. It functions much like the leading name brands you might find in the pharmacy aisle but at a significantly more accessible price point. The 48-pack provides plenty of doses to carry you through a full recovery cycle, making it a reliable staple for your medicine cabinet when the flu hits.

What We Like
Cough suppressant formula
Multi-symptom relief
Liquid softgel capsules
Nighttime sleep aid
Affordable relief

Robitussin Maximum Strength Severe Nighttime Multi-Symptom Cough, Cold and Flu Medicine, Nighttime CF Max, Raspberry Flavor - 4 Fl Oz Bottle

Robitussin Maximum Strength Severe Nighttime Multi-Symptom Medicine

4.7 (1,602 ratings)
ROBITUSSIN PF75212 2.00 X 2.00 X 5.00 Inches 0.25 Pounds

Reviews for ROBITUSSIN (PM Score)

9.8 PM Score
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  • One 4 fl oz bottle of Robitussin Maximum Strength Severe Nighttime Multi-Symptom Cough, Cold and Flu Medicine, Nighttime CF Max, Raspberry Flavor
  • Robitussin multi symptom nighttime cold medicine provides multi symptom relief and acts as a nasal decongestant
  • Quick and easy-to-use liquid cough suppressant formula contains no dextromethorphan and has acetaminophen, a fever reducer and pain reliever. Health Concern: Cold Flu Cough
  • Raspberry flavored cough and cold medicine for pain and temporary nasal congestion relief
  • Robitussin nighttime cold and flu formula helps you get a good night's sleep
  • Robitussin maximum strength severe multi symptom relief for adults and children 12 years and over, not for use in children under 12 years
  • Take 20 mL of this cold and flu remedy for adults and children 12 years and over every 4 hours for temporary multi symptom severe congestion relief
  • Do not take more than 6 doses in any 24 hour period
  • HSA and FSA eligible product
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

It is easy to assume that all nighttime cough syrups are created equal, but this Robitussin formula actually targets a specific set of severe symptoms that usually keep you tossing and turning. I found that the combination of a nasal decongestant and acetaminophen works effectively to tackle both congestion and fever-related discomfort simultaneously. Because it lacks dextromethorphan, it offers a different approach to relief while maintaining a pleasant raspberry flavor that isn't overly medicinal. It is specifically designed for adults and those aged 12 and older, providing a reliable way to manage multi-symptom cold and flu issues so you can finally get some restorative sleep. Just be sure to stick to the 20 mL dosage every four hours and avoid exceeding six doses in a day.

What We Like
Raspberry flavor
Nasal decongestant
Fever reducer
Nighttime relief
HSA/FSA eligible

Vicks DayQuil Cold & Flu Medicine, Non-Drowsy Powerful Multi-Symptom Daytime Relief For Headache, Fever, Sore Throat, Minor Aches And Pains, Nasal Con...

Vicks DayQuil Multi-Symptom Daytime Cold Relief Liquicaps

4.8 (569 ratings)
VICKS 01443BX 4.31 X 1.06 X 0.00 Inches 0.10 Pounds

Reviews for VICKS (PM Score)

9.8 PM Score
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  • POWERFUL MULTI-SYMPTOM RELIEF for your headache, fever, sore throat, minor aches and pains, nasal congestion, sinus pressure, and cough
  • NON-DROWSY, DAYTIME COLD & FLU RELIEF: DayQuil Cold & Flu Liquicaps temporarily relieve common cold & flu symptoms so you can get on with your day
  • FEEL BETTER FAST: Just one dose of DayQuil starts working fast to provide effective cold & flu relief
  • POWER THROUGH YOUR WORST COLD & FLU SYMPTOMS: Life doesn’t stop when you have a cold, DayQuil relieves bothersome symptoms such as cough and fever so that you can power through your day
  • WORLD'S #1 SELLING OTC COUGH AND COLD BRAND** Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
A and G Distribution 6.28 Yes Yes Yes

Busy professionals and parents who refuse to let a sudden illness derail their schedule need Vicks DayQuil in their medicine cabinet immediately. This non-drowsy formula is designed specifically for those high-stakes daytime hours when you need to tackle a headache, sinus pressure, or a nagging cough without feeling foggy or sluggish. The Liquicaps are incredibly convenient for fast-acting relief, targeting everything from fever and sore throats to minor aches and nasal congestion in one go. Instead of being sidelined by flu symptoms, you can actually power through your responsibilities. It is a reliable, heavy-hitting option from a brand that has been a household staple for over a century, making it a smart choice when you need to feel better fast.

What We Like
Non-drowsy formula
Multi-symptom relief
Fast-acting liquicaps
Relieves sinus pressure
Daytime cold relief

Maximum Strength Mucinex Fast-Max Cold, Flu, & Sore Throat Liquid Gels, 16ct, Controls Cough, Thins & Loosens Mucus, Relieves Nasal & Chest Congestion...

Mucinex Fast-Max Cold, Flu, and Sore Throat Liquid Gels

4.7 (816 ratings)
MUCINEX 379131 3.54 X 1.06 X 0.00 Inches 0.10 Pounds

Reviews for MUCINEX (PM Score)

9.7 PM Score
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  • MAXIMUM STRENGTH RELIEF: Maximum Strength Mucinex Fast-Max Cold, Flu & Sore Throat helps reduce fever, relieve cough, sore throat, stuffy nose, chest & nasal congestion, headache and minor aches and pains
  • #1 TRUSTED COUGH & COLD: #1 Cough & Cold Brand Doctors Trust* and #1 Pharmacist Recommended Brand
  • PAIN RELIEVER: Contains Acetaminophen which reduces fever and relieves minor aches and pains thereby relieving your sore throat pain
  • COUGH SUPPRESSANT: Contains Dextromethorphan HBr that helps relieve cough
  • EXPECTORANT: Contains Guaifenesin that thins and loosens mucus. Relieves chest congestion
  • NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure
  • USAGE: Use as directed. For ages 12+ years
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
BNT DISTRIBUTOR 7.38 No No No

Busy adults battling a sudden fever and heavy chest congestion need this heavy-hitting formula in their medicine cabinet immediately. Mucinex Fast-Max doesn't just target one symptom. It acts as a multi-tool for when a cold turns into a full-blown flu. I found the combination of Guaifenesin to thin out stubborn mucus and Phenylephrine HCl to clear nasal pressure particularly effective for getting through a rough night. Because it includes Acetaminophen, it doubles as a pain reliever for those nagging headaches and sore throat aches that usually accompany respiratory issues. It is a highly concentrated, maximum-strength option for anyone aged 12 and up who cannot afford to be sidelined by sinus pressure and coughing fits.

What We Like
Thins chest mucus
Relieves nasal congestion
Suppresses persistent cough
Reduces fever
Relieves minor aches

Cepacol Extra Strength Sore Throat Relief Lozenges, Mixed Berry Cough Drops, Maximum Numbing- Fast Acting Sore Throat & Canker Sore Relief with Dextro...

Cepacol Extra Strength Mixed Berry Sore Throat Lozenges

4.7 (102 ratings)
CEPACOLÃ'Â U363824740164-2 4.53 X 3.31 X 0.94 Inches 0.11 Pounds

Reviews for CEPACOLÃ'Â (PM Score)

9.7 PM Score
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  • Fast-acting relief: Cepacol Extra Strength Sore Throat Relief Lozenges provide maximum numbing action, offering fast relief from sore throat and canker sores.
  • Effective ingredients: Formulated with Dextromethorphan and Benzocaine, these lozenges target throat discomfort, suppressing coughs and soothing soreness for enhanced comfort.
  • Mixed Berry flavor: Enjoy the delicious taste of mixed berries while soothing your throat. The pleasant flavor makes taking these lozenges a more enjoyable experience.
  • Maximum strength formula: With extra strength properties, these lozenges deliver powerful relief, helping you get through the day without the hindrance of a sore throat.
  • Convenient pack: Each pack contains 16 individually wrapped lozenges, making them easy to carry and use on-the-go. Whether at work, school, or traveling, relief is always within reach.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
westlake 9.87 Yes Yes Yes

After weeks of testing various remedies for persistent throat irritation, the Cepacol Extra Strength lozenges stood out as a heavy hitter for immediate relief. These aren't your standard sugar drops. The combination of benzocaine and dextromethorphan creates a powerful numbing sensation that tackles both soreness and coughs simultaneously. I found the mixed berry flavor surprisingly pleasant, which helps mask the medicinal undertones often found in maximum strength formulas. The individual wrapping is a huge plus for my daily routine, allowing me to toss a few into my bag for relief at work or while traveling. If you are dealing with painful canker sores or a scratchy throat that won't quit, this formula provides the aggressive relief needed to get through the day.

What We Like
Maximum numbing action
Mixed berry flavor
Fast-acting relief
Individually wrapped
Dual-action formula

Theraflu Max Strength Daytime Flu Symptom Relief, Honey and Elderberry Syrup, 8.3 Fl Oz and Nighttime Flu Symptom Relief, Honey Lemon - 6 Count

Theraflu Max Strength Daytime and Nighttime Flu Relief Kit

4.7 (355 ratings)
THERAFLU

Reviews for THERAFLU (PM Score)

9.7 PM Score
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  • One 8.3 fl oz bottle of Theraflu Max Strength (1) Daytime Flu Symptom Relief, Honey and Elderberry Flavored Syrup plus 6 powder packets of Theraflu Max Strength (1) Nighttime Flu Symptom Relief
  • Powerful relief from flu symptoms such as sore throat pain, headache, body aches and pains, cough and fever
  • Theraflu flu symptom relief syrup is easy to take
  • Each dose of daytime syrup contains acetaminophen 1,000 mg and dextromethorphan HBr 30 mg
  • Each nighttime packet contains acetaminophen 1,000 mg, dextromethorphan HBr 30 mg and chlorpheniramine maleate 4 mg
  • Adults and children ages 12 and older take this flu symptom relief liquid every six hours as needed for symptom relief. Do not take more than 3 doses in 24 hours unless directed by a doctor
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Theraflu Max Strength offers a dual-action strategy that tackles the flu from sunrise to sunset. This kit is a lifesaver when you are caught between the need to stay functional during the day and the desperate need to sleep through the night. The daytime honey and elderberry syrup provides a potent 1,000 mg dose of acetaminophen alongside dextromethorphan to manage aches and coughs without making you drowsy. Once evening hits, the nighttime powder packets switch gears by adding chlorpheniramine maleate to help you actually rest. It is a comprehensive approach for adults and teens twelve and older, covering everything from fever and sore throats to those nagging body pains in one convenient bundle.

What We Like
Honey elderberry syrup
Nighttime powder packets
Powerful fever relief
Cough suppressant included
Dual-action formula

Robitussin Adult Maximum Strength Cough Plus Chest Congestion DM Max, Non-Drowsy Cough Suppressant and Expectorant, Raspberry Flavor, 8 Fl Oz x 2

Robitussin Maximum Strength Cough and Congestion Relief

4.7 (216 ratings)
ROBITUSSIN 0.50 Pounds

Reviews for ROBITUSSIN (PM Score)

9.7 PM Score
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  • Two 8 fl oz bottles of Robitussin Adult Maximum Strength Cough Plus Chest Congestion DM Max, Non-Drowsy Cough Suppressant and Expectorant, Raspberry Flavor
  • Cough suppressant for non-drowsy control and relief for cough and an expectorant for relief of chest congestion
  • Maximum-strength cough relief formula with expectorant that thins and loosens mucus for productive coughs
  • Raspberry flavored, daytime cough medicine delivers fast, effective cough relief
  • Cough suppressant and liquid expectorant suitable for adults and children 12 years and over
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Most people assume that effective cough suppression requires a sedative that knocks you out, but this formula proves otherwise. I found that this Robitussin blend manages to tackle that heavy, rattling chest congestion without the dreaded midday fog. It works through a dual-action approach: the expectorant thins out stubborn mucus to make your coughs more productive, while the suppressant keeps the irritation in check. The raspberry flavor is actually quite pleasant for a drugstore liquid, making it much easier to swallow during a rough cold. Since it is designed for adults and those twelve and older, it serves as a reliable daytime option for anyone needing fast, non-drowsy relief from a persistent cough.

What We Like
Non-drowsy formula
Thins chest mucus
Raspberry flavor
Maximum strength relief
Two bottle pack

Robitussin Honey Severe Cough, Flu & Sore Throat Nighttime Max Syrup, Ages 12+, 8 oz

Robitussin Honey Nighttime Max Cough Relief Syrup

4.6 (393 ratings)
ROBITUSSIN F00031877018 2.38 X 2.38 X 6.25 Inches 0.50 Pounds

Reviews for ROBITUSSIN (PM Score)

9.6 PM Score
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  • Robitussin Honey Severe Cough, Flu & Sore Throat Nighttime Max Syrup helps calm cough and cold or flu symptoms
  • Helps control your cough so you can sleep
  • Relieves fever, body aches, runny nose, and sneezing, and alleviates sore throat pain
  • Maximum strength cough relief with Acetaminophen and Diphenhydramine
  • Combines the great taste of real honey you want with the powerful effective cough relief you need
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

You might wonder if a syrup can actually handle a full-blown flu, but this Robitussin formula is built for those heavy-hitting nighttime symptoms. I found that the combination of Acetaminophen and Diphenhydramine does the heavy lifting, tackling fever and body aches while the antihistamine helps quiet the sneezing and runny nose. It specifically targets that persistent, hacking cough that keeps you tossing and turning, making it much easier to actually get some rest. The real standout is the flavor profile. It avoids that medicinal aftertaste by incorporating real honey, which makes the experience far less unpleasant when you are feeling miserable. It is a heavy-duty solution for anyone aged 12 and up needing maximum strength relief.

What We Like
Real honey flavor
Maximum strength relief
Controls nighttime cough
Relieves body aches
Soothes sore throats

RIGHT REMEDIES Cough Relief Softgels, Dextromethorphan HBr 15mg, up to 8-Hour Long-Lasting, Non Drowsy Bronchial Suppressant (60 Softgels)

Right Remedies Dextromethorphan HBr Cough Relief Softgels

RIGHT REMEDIES

Reviews for RIGHT REMEDIES (PM Score)

9.3 PM Score
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  • ✅ COUGH & COLD RELIEF: Whether for a dry or wet cough, Right Remedies softgels can provide up to 8-hours of continuous relief with fast acting results
  • ✅ COUGH SUPPRESSANT: Right Remedies cough relief softgels temporarily relieves cough due to minor throat and bronchial irritation as may occur with the common cold.
  • ✅ EASY TO SWALLOW: These softgels are easier to take than ill-tasting liquids or dry pills that leave aftertaste. This product reaches digestive system and starts working faster and efficiently.
  • ✅ MANUFACTURED: In a UL GMP certified facility. Packaged and quality assured in the USA.
  • ✅ COMPARE TO: Active ingredient of Robitussin Coughgels
  • ✅ DIRECTIONS: For children and adults ages 12 and over. Please follow the directions closely to ensure proper safety and use.
  • ✅ 100% SATISFACTION GUARANTEE:</b> We know you will love this product that comes with a tamper-evident safety
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Right Remedies 9.86 Yes Yes Yes

After weeks of fighting a persistent, irritating cough that kept me up at night, I finally found relief with these Right Remedies softgels. Unlike those thick, medicinal-tasting syrups that linger unpleasantly in your throat, these softgels are incredibly easy to swallow and go down without any weird aftertaste. The 15mg of Dextromethorphan HBr works quickly to soothe bronchial irritation, providing a solid eight hours of continuous suppression. It is a massive relief to find a non-drowsy option that actually works for both dry and wet coughs. Knowing they are manufactured in a UL GMP certified facility in the USA gives me extra peace of mind regarding the quality and safety of what I am taking.

What We Like
Eight-hour relief
Non-drowsy formula
Easy to swallow
Fast acting
Bronchial suppressant

Cabinet Non-Drowsy Cough Relief Softgels w/ Active Ingredient Dextromethorphan Comparable to Robitussin® CoughGels®, 1 Refillable Medicine Jar, 60 Sof...

Cabinet Non-Drowsy Cough Relief Softgels

CABINET: 3.00 X 3.00 X 5.00 Inches

Reviews for CABINET: (PM Score)

9.3 PM Score
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  • Active Ingredient for Quick Cough Suppression: Cabinet Cough Relief contains active ingredient Dextromethorphan HBr 15 mg which is comparable to the active cough suppressant ingredient in Robitussin Cough Gels.
  • Non-Drowsy Relief for Adults and Children: Adults and children over the age of 12 can take 2 capsules every 6 to 8 hours to suppress cough symptoms that can be the result of a cold or flu. The non-drowsy effects of dextromethorphan can take effect within 30 to 60 minutes. Suitable for daytime or nighttime use.
  • Convenient Packaging and Easy-to-Swallow Pills: Skip the cough syrup and cough drops and soothe dry cough symptoms quickly! Our child-proof packaging conveniently snaps shut to keep your medicine and little ones safe. Cabinet medicine bottles are designed for durability and can be refilled over-and-over to reduce plastic waste!
  • Third Party, Quality Tested: Put your mind (and the planet) at ease when you purchase Cabinet. Our maximum strength cough relief softgels are held to the highest manufacturing standards and are batch-level quality tested for allergens, carcinogens, gluten, and purity.
  • The Only Sustainable Cough Medicine for Adults: Over 194 billion plastic medicine bottles are produced every year and about 90% of them end up in our oceans. These plastic bottles break down in our oceans and into microplastics that are then consumed by animals and humans. Humans ingest the amount of plastic in one credit card. Every week.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Cabinet Health 9.73 Yes Yes Yes

Why settle for single-use plastic waste every time a seasonal cold hits your household? Cabinet has completely reimagined the medicine cabinet by pairing effective Dextromethorphan HBr relief with a truly sustainable approach. These softgels provide quick, non-drowsy cough suppression within 30 to 60 minutes, making them just as reliable for daytime productivity as they are for nighttime rest. I was particularly impressed by the commitment to quality. Every batch undergoes rigorous testing for allergens and purity. The standout feature, however, is the refillable medicine jar. Instead of contributing to the billions of plastic bottles that clog our oceans, you can simply refill your durable, child-proof container. It is a rare win-win that delivers maximum strength relief without the environmental guilt.

What We Like
Refillable medicine jar
Non-drowsy formula
Quick cough suppression
Batch-tested purity
Sustainable packaging
#18

Strepsils Throat Lozenges Soothing Honey & Lemon 16 Pack

Strepsils Honey and Lemon Throat Lozenges

4.6 (67 ratings)
STREPSILS 300711074378 5.12 X 2.76 X 1.97 Inches 0.22 Pounds

Reviews for STREPSILS (PM Score)

8.0 PM Score
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  • Soothing throat relief: Strepsils Throat Lozenges provide soothing relief for sore throats, offering comfort and reducing discomfort.
  • Honey and lemon flavor: The lozenges have a pleasant honey and lemon flavor, which adds a soothing and refreshing taste during use.
  • 16 pack: Each purchase includes a pack of 16 lozenges, ensuring an ample supply for multiple uses or sharing with others.
  • Trusted brand: Strepsils is a well-known and trusted brand in providing comfort to throat.
  • Convenient and portable: The lozenges are individually wrapped, making them easy to carry and use on the go.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
FATMA ARSLAN 9.90 Yes Yes Yes

A sudden, scratchy irritation during a long afternoon meeting can make it nearly impossible to focus on anything but your own discomfort. Strepsils Honey and Lemon lozenges are designed specifically to tackle that exact moment of throat distress. I found the honey and lemon flavor to be genuinely pleasant and refreshing, which makes the soothing process much more tolerable than medicinal alternatives. The 16-pack provides a solid supply for a week of discomfort, and because each lozenge is individually wrapped, you can easily toss a few into a bag or pocket for quick relief while traveling. It is a reliable, portable solution from a brand that has built significant trust in the drugstore category.

What We Like
Soothing honey lemon flavor
Individually wrapped lozenges
Portable relief
Trusted brand formula
Sixteen count pack

Vicks NyQuil LiquiCaps, Nighttime Relief of Cough, Cold & Flu Relief, Sore Throat, Fever, & Congestion Relief, 48 LiquiCaps

Vicks NyQuil LiquiCaps Nighttime Cold and Flu Relief

VICKS 323900014411 4.25 X 2.00 X 3.31 Inches 0.22 Pounds

Reviews for VICKS (PM Score)

0.0 PM Score
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  • FAST, POWERFUL MULTI-SYMPTOM RELIEF for your headache, fever, sore throat, minor aches and pains, sneezing, runny nose, and cough
  • EFFECTIVE NIGHTTIME COLD & FLU SYMPTOM RELIEF. NyQuil Cold & Flu Liquicaps temporarily relieves common cold & flu symptoms so you can get the rest you need
  • FAST RELIEF SO YOU CAN SLEEP. Don't let your cold keep you up. Just one dose of NyQuil starts working fast to provide effective cold & flu relief
  • POWER THROUGH YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil relieves bothersome symptoms such as cough and fever so that you can get the rest you need
  • WORLD'S #1 SELLING OTC COUGH AND COLD BRAND**. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Nighttime sickness is a thief that steals your sleep, and Vicks NyQuil LiquiCaps is the heavy-duty defense you need to reclaim your rest. I’ve found that when a fever or a persistent cough starts keeping you tossing and turning, you need something that works fast rather than waiting around for relief. These Liquicaps are designed to tackle a massive range of symptoms at once, from sore throats and minor aches to that annoying runny nose and sneezing. Because it targets the congestion and cough that usually disrupt your sleep cycle, it actually helps you power through the worst of a cold. It is a reliable, multi-symptom solution for anyone who needs to stop worrying about their symptoms and finally get some much-needed shut-eye.

What We Like
Fast-acting relief
Multi-symptom formula
Nighttime cough suppressant
Fever reducer
LiquiCap delivery

ALKA-SELTZER PLUS Severe Cold - Sparkling Original Powerfast Fizz Effervescent Common Cold Tablets, Sinus Congestion, Runny Nose, and Dry Cough, 36CT

Alka-Seltzer Plus Severe Cold Effervescent Tablets

4.8 (1,813 ratings)
ALKA-SELTZER PLUS
  • ALKA-SELTZER PLUS Severe Cold Sparkling Original POWERFAST Fizz EFFERVESCENT Cold Tablets provide fast relief from cold symptoms
  • Our severe cold, cough formula provides fizzy fast relief of: nasal congestion, sinus pressure & congestion, sneezing, runny nose, headache, fever, sore throat and body aches & pains.
  • Provides severe cold relief from congestion, coughing, and sore throat
  • Each box containing 18 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes this cold remedy easy to take with you on the go.
  • Works as flu and cold relief with acetaminophen as an ingredient
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

The aggressive fizz of these effervescent tablets hitting the water is the first sign that this formula is working hard to tackle your symptoms. I found that the Powerfast fizz makes the medicine much easier to swallow than traditional pills, especially when you are dealing with a scratchy, sore throat. This severe cold formula is a heavy hitter, utilizing acetaminophen to knock down fevers and body aches while simultaneously clearing out sinus pressure and nasal congestion. It is particularly effective for those stubborn dry coughs and runny noses that make it impossible to rest. Because the doses come in individually wrapped sachets, you can easily toss a couple into a bag for relief while traveling or working, ensuring you aren't caught off guard by a sudden bout of flu-like symptoms.

What We Like
Fast fizzing relief
Individual sachets
Clears sinus pressure
Includes acetaminophen
Targets dry cough

Alka-seltzer Plus Cold & Flu, Power Max Cold and Flu Medicine, Day, For Adults with Pain Reliver/Fever Reducer, Cough Suppressant, Nasal Decongestant,...

Alka-Seltzer Plus PowerMax Cold and Flu Day Gels

4.7 (1,160 ratings)
ALKA-SELTZER PLUS I00104723 3.50 X 1.50 X 0.00 Inches
  • NEW 25 percent smaller pill: Alka Seltzer Plus Maximum Strength Cold & Flu PowerMax Gels have a concentrated formula in a smaller liquid gel so it's easier to swallow
  • Provides up to 4 hours of relief: one dose provides 4 hour day time relief of cough, nasal congestion, headache & body ache, sore throat, and sinus pressure
  • Alka Seltzer Plus Maximum Strength Cold & Flu PowerMax Gels contain a pain reliever, fever reducer, cough suppressant, and nasal decongestant
  • Temporarily relieves these symptoms due to a cold or flu: Minor aches and pains, cough, headache, sore throat, & nasal and sinus congestion. Temporarily reduces fever
  • PowerMax Gels do not have to be taken with meals
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Hammond K&T 9.12 Yes Yes Yes

You might wonder if a smaller pill can actually pack enough punch to tackle a heavy flu, but these PowerMax liquid gels are designed to prove otherwise. I found the new formula particularly impressive because the capsules are 25 percent smaller than previous versions, making them significantly easier to swallow without that awkward medicinal struggle. Even with the reduced size, the concentrated formula delivers a robust four-hour window of relief for those miserable symptoms like sinus pressure, sore throats, and body aches. It acts as a true multi-symptom powerhouse, combining a pain reliever, fever reducer, cough suppressant, and decongestant into one convenient dose. Best of all, you don't have to worry about timing your dose around a meal to get the full effect.

What We Like
Smaller easy-to-swallow gels
Four-hour symptom relief
Concentrated liquid formula
Multi-symptom relief
No food required

Vicks Nyquil Cold and Flu Nighttime Relief Liquid Capsules, 16 Count

Vicks NyQuil Cold and Flu Nighttime Relief Liquid Capsules

4.8 (401 ratings)
VICKS 604959 1.06 X 1.06 X 3.25 Inches 0.02 Pounds

Reviews for VICKS (PM Score)

9.8 PM Score
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  • Temporarily relieves common cold and flu symptoms including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Tossing and turning at 3:00 AM with a hacking cough and a pounding headache is a special kind of misery. I turned to these Vicks NyQuil liquid capsules when my seasonal flu symptoms made sleep feel impossible. Unlike traditional syrups that can feel heavy or messy, these capsules provide a streamlined way to target that stubborn bronchial irritation and sore throat. They hit the mark on multiple fronts, tackling fever, runny nose, and sneezing all at once. It is a reliable heavy hitter for those nights when you just need the aches and pains to subside so you can actually get some rest. For a small 16-count pack, it is a solid addition to any home medicine cabinet for emergency relief.

What We Like
Liquid capsule form
Relieves cough
Reduces fever
Soothes sore throat
Eases minor aches

HealthA2Z Nighttime Cold & Flu Relief | 20 Count Softgels | Compare to Vicks® Nyquil® Cold & Flu Liqui Caps Active Ingredient

HealthA2Z Nighttime Cold and Flu Relief Softgels

4.7 (244 ratings)
HEALTHA2Z FP0696 4.33 X 1.16 X 3.50 Inches 0.11 Pounds

Reviews for HEALTHA2Z (PM Score)

9.7 PM Score
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  • Compare to VicksNyquil Cold & Flu LiquiCaps / Each softgel contains Acetaminophen 325mg,Dextromethorphan HBr 15mg, Doxylamine succinate 6.25mg.
  • Rrelieves multi-symptoms of cold and flu : aches and pains / sore throat/headache / cough due to minor throat and bronchial irriation / fever / pain / runny nose and sneezing.
  • Our small and compact packages are light weight and can easily fit in your purse, luggage, glove compartment, etc! The perfect mobile solution to keep you healthy and enhance your travel experience!
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
HealthA2Z 9.95 Yes Yes Yes

HealthA2Z Nighttime Cold & Flu Relief offers a potent, multi-symptom solution for those struggling to sleep through a heavy illness. These softgels pack a heavy-hitting trio of Acetaminophen, Dextromethorphan HBr, and Doxylamine succinate to tackle everything from fever and aches to that nagging bronchial cough. What really sets this apart for me is the sheer convenience of the packaging. At just 20 softgels per pack, the footprint is incredibly small, making it easy to toss into a purse, a glove compartment, or a carry-on bag for unexpected travel sickness. It provides the same relief you would expect from leading brands but in a much more mobile, travel-friendly format that fits into any lifestyle.

What We Like
Multi-symptom relief
Compact travel packaging
Nighttime formula
Easy-to-swallow softgels
Portable design

Hyland’s Naturals Baby Tiny Cold Tablets, Day & Night Value Pack, Infant and Baby Cold Medicine, Decongestant, Runny Nose & Cough Relief, 250 Quick-Di...

Hyland's Naturals Baby Tiny Cold Day and Night Pack

4.7 (164 ratings)
HYLAND'S

Reviews for HYLAND'S (PM Score)

9.7 PM Score
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  • RELIEF OF COLD: Natural relief of runny nose, congestion and sneezing due to common head colds and with Nighttime: cough and occasional sleeplessness in babies 6 months+
  • EASY TO USE: Quick-dissolving tablets that melt in your baby's mouth instantly to relieve runny nose and eyes, nighttime cough, congestion, headache, sneezing and occasional sleeplessness due to common head colds in babies 6 months+
  • 125 TABLETS OF EACH =UP TO 125 DOSES of Hyland's Baby Nighttime Tiny Cold Tablets
  • SAFE AND GENTLE: Hyland's formulas are made with natural active ingredients and have no known drug interactions.
  • KEEPING FAMILIES HEALTHY: Hyland’s Naturals is a leading consumer health brand with more than a century of history making high quality products to help people live healthier and happier lives.
  • Made in the USA
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

Hyland’s Naturals Baby Tiny Cold Tablets offer a reliable, natural approach to managing infant congestion that makes them a staple for any well-stocked nursery medicine cabinet. This value pack is incredibly practical because it splits the workload between daytime relief for runny noses and sneezing and a nighttime formula specifically designed to soothe coughs and occasional sleeplessness. Since the tablets are quick-dissolving, they melt instantly in a baby's mouth, which removes the struggle often associated with liquid medicines. It is reassuring to use a formula from a brand with over a century of history, especially knowing these active ingredients are gentle and have no known drug interactions. For parents of infants six months and older, this dual-action kit provides a seamless way to manage common head colds from sunrise to sunset.

What We Like
Quick-dissolving tablets
Day and night relief
Natural active ingredients
No drug interactions
Made in USA

Mucinex Maximum Strength Sinus-Max (Day) Pressure, Pain & Cough & Nightshift (Night) Sinus Caplets, Fast Release, Powerful Multi-Symptom Relief, 20 ca...

Mucinex Sinus-Max Day and Night Relief Pack

4.7 (64 ratings)
MUCINEX 3171954

Reviews for MUCINEX (PM Score)

7.9 PM Score
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  • MAXIMUM STRENGTH MUCINEX SINUS-MAX (DAY) PRESSURE, PAIN & COUGH & NIGHTSHIFT (NIGHT) SINUS: Fast Release, Powerful Multi-Symptom Relief medicine. Get back to what’s important thanks to the fast, powerful medicine
  • DAY TIME MULTI-SYMPTOM RELIEF: Maximum Strength Mucinex Sinus-Max Day Pressure, Pain & Cough Caplets help to relieve pain, sinus pressure & congestion, headaches, controls cough and thins & loosens mucus
  • NIGHT TIME MULTI-SYMPTOM RELIEF: Maximum Strength Mucinex Nightshift (Night) Sinus Caplets help to relieve pain, cough, reduce fever, sore throat, runny nose, sneezing & nasal congestion. Nighttime relief for a better morning!
  • #1 TRUSTED COLD & COUGH BRAND: Mucinex is the #1 Cold and Cough brand doctors trust*
  • AY TIME ACTIVE INGREDIENTS PER CAPLET: Contains Acetaminophen - Pain reliever. Dextromethorphan HBr - Cough Suppressant. Guaifenesin - Expectorant. Phenylephrine HCI - Nasal Decongestant
  • NIGHT TIME ACTIVE INGREDIENTS PER CAPLET: Contains Acetaminophen - Pain reliever. Dextromethorphan HBr - Cough Suppressant. Phenylephrine HCI - Nasal Decongestant. Triprolidine HCI - Antihistamine
  • FSA & HSA ELIGIBLE: Cover out-of-pocket expenses with pre-tax dollars.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
CP William LLC 9.91 Yes Yes Yes

Sinus congestion and persistent coughs can completely derail your productivity and sleep schedule. This Mucinex Sinus-Max dual pack provides a strategic solution by splitting your relief into two distinct phases. The daytime caplets tackle the heavy lifting, using a combination of an expectorant and decongestant to thin mucus and clear sinus pressure so you can stay focused. Once evening hits, the Nightshift formula shifts gears, adding an antihistamine to help manage sneezing, runny noses, and fever while you rest. It is a comprehensive toolkit for anyone needing to manage pain and respiratory symptoms without guessing which medication to take at which hour. Since it is FSA and HSA eligible, it is a practical addition to any home medicine cabinet.

What We Like
Day/night dual formula
Fast release relief
Thins thick mucus
Reduces sinus pressure
Controls nighttime cough

Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expect...

Tylenol Cold and Flu Severe Symptom Relief Caplets

TYLENOL 421650

Reviews for TYLENOL (PM Score)

7.4 PM Score
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  • 24-capsule (Pack of 6) of Tylenol Cold + Flu Severe Caplets provide effective relief of multiple symptoms due to the flu and common cold
  • This severe cold & flu medicine helps relieve headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
  • Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
  • From the #1 doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
MASKU LLC 9.70 Yes Yes Yes

Adults and teenagers facing the absolute worst of flu season need this heavy-hitting multi-symptom relief in their medicine cabinet immediately. This six-pack bundle is a powerhouse for anyone struggling with the combination of a hacking cough, sinus pressure, and fever. What makes this specific formula stand out is the aggressive combination of guaifenesin to thin out stubborn mucus and dextromethorphan to quiet those disruptive coughs. You aren't just masking a headache with the 325 mg of acetaminophen. You are actively tackling congestion with phenylephrine HCl and making coughs more productive. It is a comprehensive approach to feeling human again when a virus tries to knock you sideways.

What We Like
Multi-symptom relief
Effective cough suppressant
Thins bronchial secretions
Relieves nasal congestion
Fever reducer

XL-3 Night Time, Non-Drowsy, for Cold and Flu Symptoms, Helps Relieve Nasal Congestion and Fever, 6 FL Oz, Bottle.

XL-3 Xtreme Nighttime Cold and Flu Relief

4.4 (50 ratings)
XL-3 2.25 X 2.25 X 5.30 Inches 0.56 Pounds

Reviews for XL-3 (PM Score)

6.9 PM Score
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  • NIGHTTIME COLD AND COUGH: XL-3 Xtreme will help you get a good night's sleep while it relieves your cold and cough symptoms so that you can rest through the night.
  • COUGH SUPPRESSANT: Our cold and cough syrup acts as a cough suppressant to temporarily relieve irritation and sore throats. When your throat itches, and it even hurts to talk, you will feel the relief of XL-3 Xtreme.
  • MULTI-SYMPTOMS RELIEF: This cold remedy will temporarily help you relieve common cold and flu symptoms, including cough due to minor throat and bronchial irritation, sore throat, minor aches and pains, fever, runny nose, and sneezing.
  • FEVER RELIEF: XL-3 Xtreme will be of great support to help you reduce fever, headache, minor body pain, sore throat, as well as muscle aches caused by the flu.
  • LIQUID RELIEF, GREAT FLAVOR: Our formula is created with delicious cherry flavor. It is easy to swallow when you have a sore throat or feel it very irritated.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

A scratchy, irritated throat can make even the simplest conversation feel like an uphill battle. XL-3 Xtreme targets that specific discomfort by acting as a potent cough suppressant to soothe bronchial irritation and sore throats. What makes this liquid formula stand out is the delicious cherry flavor, which makes it much easier to swallow when your throat is feeling particularly sensitive. Beyond just calming a cough, it works as a multi-symptom powerhouse to tackle fever, runny noses, sneezing, and those nagging muscle aches that often accompany the flu. It is designed to help you rest through the night by managing minor aches and pains, ensuring you actually get the sleep necessary for recovery.

What We Like
Cherry flavored liquid
Cough suppressant
Fever reducer
Multi-symptom relief
Soothes sore throats

Quality Choice Maximum Strength Flu High Blood Pressure (HBP), Pain Reliever and Fever Reducer, Antihistamine & Cough Suppressant, Decongestant Free,...

Quality Choice Maximum Strength Flu HBP Medicine

QUALITY CHOICE QC99792

Reviews for QUALITY CHOICE (PM Score)

5.1 PM Score
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  • Quality Choice Maximum Strength Flu Medicine for High Blood Pressure (HBP) compares to the active ingredients in Coicidin HBP Maximum Strength Flu.
  • Max Strength Flu HBP by Quality Choice Contains Acetaminophen 325 mg, Chlorpheniramine Maleate 2 mg, Dextromethorphan HBr 10 mg
  • Quality Choice Flu HBP medicine is used to Relieve Body Aches, Headaches, Fever, Cough, Runny Nose, Sore Throat, and Sneezing to provide you with relief of Flu like symptoms.
  • Quality Choice Maximum Strength HBP Pain Reliever, Fever Reducer, Antihistamine & Cough Suppressant is Decongestant free
  • Restores Comfort and Provides Relief of Flu Symptoms for those who suffer from High Blood Pressure
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
PLQC 9.84 Yes Yes Yes

Most flu remedies force you to choose between symptom relief and managing your blood pressure, but Quality Choice offers a specialized alternative. This maximum strength formula is specifically designed for people with high blood pressure, intentionally omitting decongestants that often cause unwanted spikes. By combining Acetaminophen, Chlorpheniramine Maleate, and Dextromethorphan HBr, it tackles a massive spectrum of discomfort including body aches, fever, persistent coughs, and sneezing. It is a comprehensive solution that manages sore throats and runny noses without the cardiovascular risks associated with standard multi-symptom liquids. If you need to restore comfort during a heavy flu cycle while staying mindful of your HBP requirements, this 20-count pack provides a reliable, targeted approach to recovery.

What We Like
Decongestant free
HBP safe formula
Relieves body aches
Suppresses cough
Reduces fever

Coricidin HBP Maximum Strength Cold & Flu Day & Night Sugar-Free Liquid Twinpack, Decongestant-Free Cold Medicine for Adults with High Blood Pressure...

Coricidin HBP Maximum Strength Cold and Flu Liquid Twinpack

CORICIDIN HBP 5.13 X 2.56 X 6.90 Inches

Reviews for CORICIDIN HBP (PM Score)

0.0 PM Score
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  • Two 12 fl ounce bottles of Coricidin HBP Cold & Flu Day & Night Liquid Medicine, Cold Medicine for Adults with High Blood Pressure
  • HBP ADULT COLD MEDICINE: Decongestant-free Coricidin cold & flu medicine relieves symptoms without elevating blood pressure
  • BODY ACHES AND PAIN RELIEF: Acetaminophen reduces fever and relieves pain, including sore throat, headaches and body aches
  • COUGH RELIEF: A cough suppressant and expectorant temporarily relieves coughs and loosens congestion
  • MAXIMUM STRENGTH RELIEF: Coricidin HBP cold, cough & flu maximum strength medicine provides fast relief of symptoms for up to 4 hours
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

After weeks of searching for a way to manage flu symptoms without compromising my cardiovascular health, this liquid twinpack finally offered a solution. Coricidin HBP stands out because it is specifically formulated to be decongestant-free, which is a massive relief for adults monitoring their blood pressure. The acetaminophen works effectively to knock down fever and soothe those nagging body aches or sore throats that make getting through the day impossible. I found the dual-action approach of a cough suppressant combined with an expectorant to be particularly helpful for loosening congestion. While the maximum strength relief lasts about four hours, having both day and night formulas in one package makes managing a sickness much more streamlined and predictable.

What We Like
Decongestant-free formula
Blood pressure safe
Fast symptom relief
Sugar-free liquid
Cough suppressant included

Tylenol Day and Night Cold and Flu Capsule, 24 Count per Pack - 48 per case.

Tylenol Day and Night Cold and Flu Relief Combo

TYLENOL

Reviews for TYLENOL (PM Score)

0.0 PM Score
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  • DAYTIME RELIEF CAPLETS: Formulated to reduce fever, loosen phlegm, and relieve headache, body aches, cough, sore throat, stuffy nose, and chest congestion
  • NIGHTTIME RELIEF CAPLETS: Help reduce fever and relieve runny nose, sneezing, headache, cough, sore throat, nasal congestion, sinus congestion, and pressure
  • EACH COLD AND FLU CAPLET: Contains 325 mg of acetaminophen, a pain reliever and fever reducer. 5 mg phenylephrine HCl, a nasal decongestant. And 10 mg of dextromethorphan HBr, a cough suppressant
  • DAYTIME CAPSLETS: Contain guaifenesin 200 mg, an expectorant to help loosen phlegm (mucus) to make a cough more productive. The night capsules also contain 2 mg of chlorpheniramine maleate, an antihistamine
  • #1 DOCTOR-RECOMMENDED BRAND: Combo pack of 24 capsules of Tylenol Cold + Flu Severe Day/Night to relieve cold and flu symptoms. Combo Pack includes 16 Day Capsules and 8 Night Capsules for any time of day relief
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Royal Meds 9.95 No No No

Waking up with a heavy chest and a pounding headache can derail your entire work week before it even begins. This Tylenol combo pack acts as a strategic toolkit for those exact moments, offering specialized relief that shifts with your circadian rhythm. The daytime capsules utilize guaifenesin to help loosen phlegm and make your cough more productive, while the nighttime formula incorporates chlorpheniramine maleate to tackle sneezing and runny noses. Because each dose contains a consistent blend of acetaminophen, phenylephrine HCl, and dextromethorphan HBr, you aren't constantly guessing which ingredient is doing the heavy lifting. It is a reliable, doctor-recommended way to manage fever, congestion, and body aches without having to juggle multiple different medicine bottles.

What We Like
Day and night relief
Loosens phlegm
Reduces fever
Nasal decongestant
Cough suppressant
Buying Guide

A Guide to Selecting the Best capsule cough sore throat medicine

A Guide to Selecting the Best capsule cough sore throat medicine

Identify Your Primary Symptom Type

The most critical step in selecting a capsule is determining whether your cough is 'productive' or 'non-productive.' A productive cough (wet cough) is characterized by mucus or phlegm. In this case, you should look for capsules containing an expectorant, such as guaifenesin. Expectorants work by thinning the mucus in your airways, making it easier to cough up. Conversely, if you have a dry, hacking, or tickling cough that keeps you awake, you need a suppressant, typically containing dextromethorphan. Taking a suppressant for a wet cough can actually be counterproductive, as it prevents your body from clearing necessary secretions from your lungs.

Evaluate Multi-Symptom vs. Single-Ingredient Formulas

Many capsule formulations are 'multi-symptom' relief kits. These are highly efficient if you are battling a full cold or flu, as they often combine a cough suppressant, an expectorant, a pain reliever (like acetaminophen), and sometimes a decongestant. While convenient, these require careful reading of the 'Drug Facts' label. If you are already taking a separate medication for a headache, taking a multi-symptom capsule might lead to accidental double-dosing of pain relievers. If your symptoms are isolated—for example, if you only have a sore throat but no congestion—it is often more effective and safer to choose a single-ingredient capsule to avoid unnecessary chemical intake.

Address the Sore Throat Component

For the sore throat aspect, look for capsules that include analgesics. While lozenges provide localized, temporary numbing, capsules provide systemic relief. An analgesic like acetaminophen or ibuprofen within a capsule works to reduce the inflammation and pain throughout the throat tissues. If your sore throat is accompanied by sinus pressure, ensure the capsule includes a decongestant to reduce the post-nasal drip that often irritates the throat in the first place.

Consider Delivery Speed and Duration

Capsules are generally designed for sustained release or standard absorption. Pay attention to the 'duration of relief' mentioned on the packaging. Some advanced capsule technologies are designed to release medication slowly over 8 to 12 hours, which is ideal for nighttime use to prevent cough-induced sleep disruption. If you need rapid relief for an acute bout of coughing, check if the formulation is optimized for quick dissolution. Always consider the frequency of dosing. A 12-hour capsule is often more convenient for busy schedules than a formula that requires dosing every four hours.

Safety and Interaction Awareness

Before finalizing your purchase, always cross-reference the active ingredients with any other medications you are currently taking. For instance, many cough capsules contain decongestants that can raise blood pressure, which may be a concern for individuals with hypertension. Additionally, always check for warnings regarding alcohol consumption or driving, as some cough suppressants can cause drowsiness.

Ready to choose?

Jump back to our ranked picks or compare the shortlist side by side.

Frequently Asked Questions

Quick answers about Capsule Cough Sore Throat Medicine before you buy.

Suppressants, often containing dextromethorphan, work by blocking your cough reflex to stop dry hacking. Expectorants, like guaifenesin, thin the mucus in your airways to make coughs more productive and easier to clear.

Multi-symptom capsules are best if you are dealing with a cluster of issues like a fever, congestion, and a sore throat simultaneously. If you only have a dry cough, a single-ingredient suppressant is often more targeted.

While many cough medicines can be taken without food, some active ingredients may cause mild stomach upset. If you have a sensitive stomach, taking your dose with a small snack is recommended.

It depends on the active ingredients. Capsules containing antihistamines (often used for runny noses) frequently cause drowsiness, while non-drowsy formulas focus solely on cough and throat relief.

Most oral capsules begin to provide relief within 15 to 30 minutes, though the full effect on congestion or mucus thinning may take longer to stabilize.

No. You should avoid 'double-dosing' by taking two different products that contain the same active ingredient, as this can lead to an accidental overdose.

Always follow the specific dosing instructions on the product packaging. Generally, most capsules are taken every 4 to 6 hours, but exceeding the recommended daily limit can be dangerous.

While capsules primarily target the cough reflex, some multi-symptom formulas include pain relievers like acetaminophen, which can help soothe the inflammation and pain associated with a sore throat.
Research & Insights

Our Analysis of Capsule Cough Sore Throat Medicine

78,053 Reviews Analyzed
33 Products Evaluated
8.0 Avg PM Score
10 Brands Ranked

Top 10 Capsule Cough Sore Throat Medicine Brands on Amazon

Share of top-ranked products by brand, from our editorial analysis.

  1. 01 Vicks 5 (19.2%)
  2. 02 Amazon Basic Care 4 (15.4%)
  3. 03 Mucinex 4 (15.4%)
  4. 04 Alka-Seltzer Plus 2 (7.7%)
  5. 05 Coricidin Hbp 2 (7.7%)
  6. 06 Quality Choice 2 (7.7%)
  7. 07 Theraflu 2 (7.7%)
  8. 08 Tylenol 2 (7.7%)
  9. 09 Valumeds 2 (7.7%)
  10. 10 Beekeeper's Naturals 1 (3.8%)

What Our Analysis Found

We've carried out a comprehensive analysis of 78,053 reviews on Capsule Cough Sore Throat Medicine, using our selection criteria to identify the best options in the health care. Our findings reveal that most customers typically select Capsule Cough Sore Throat Medicine priced around $26.59, with top brands including tylenol, valumeds, vicks, wedderspoon, robitussin, mucinex, alka-seltzer plus, amazon basic care and beekeeper's naturals and theraflu.

Our team of expert editors reviewed these high-quality items and handpicked the top 30 Capsule Cough Sore Throat Medicine for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health care category — including amazon.com, deep seas wares, valumeds, bnt distributor, beekeeper's naturals, serenity satchel, cabinet health, the customer land and marcopolo commerce inc. and stam sales.

We are dedicated to assisting our users in finding the right medicine Products based on their needs, saving them considerable time when choosing which Capsule Cough Sore Throat Medicine to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.

Side by Side

Comparison Table

Compare the top 30 picks at a glance — select a column to sort.

# Product Brand PM Score Rating Where to Buy
1 Amazon Basic Care Daytime Cold and Flu Relief Amazon Basic Care 9.9 4.7 (12,125) Buy on Amazon
2 Beekeeper's Naturals Propolis Throat Spray Beekeeper's Naturals 9.9 4.5 (18,517) Buy on Amazon
3 Vicks NyQuil Cold and Flu Relief Liquicaps Vicks 9.9 4.9 (147) Buy on Amazon
4 Vicks DayQuil LiquiCaps Cold and Flu Relief Vicks 9.9 4.8 (2,765) Buy on Amazon
5 Mucinex Fast-Max Multi-Symptom Day and Night Liquid Gels Mucinex 9.9 4.8 (1,124) Buy on Amazon
6 Contac Maximum Strength Cold and Flu Daytime Relief Contac 9.8 4.7 (1,276) Buy on Amazon
7 ValuMeds Nighttime Cough and Cold Relief Softgels ValuMeds 9.8 4.7 (1,596) Buy on Amazon
8 Robitussin Maximum Strength Severe Nighttime Multi-Symptom Medicine Robitussin 9.8 4.7 (1,602) Buy on Amazon
9 Nin Jiom Pei Pa Koa - Sore Throat Syrup - 100% Natural (Hone 9.8 4.7 (1,070) Buy on Amazon
10 Vicks DayQuil Multi-Symptom Daytime Cold Relief Liquicaps Vicks 9.8 4.8 (569) Buy on Amazon
11 Mucinex Fast-Max Cold, Flu, and Sore Throat Liquid Gels Mucinex 9.7 4.7 (816) Buy on Amazon
12 Cepacol Extra Strength Mixed Berry Sore Throat Lozenges CepacolÃ'Â 9.7 4.7 (102) Buy on Amazon
13 Theraflu Max Strength Daytime and Nighttime Flu Relief Kit Theraflu 9.7 4.7 (355) Buy on Amazon
14 Robitussin Maximum Strength Cough and Congestion Relief Robitussin 9.7 4.7 (216) Buy on Amazon
15 Robitussin Honey Nighttime Max Cough Relief Syrup Robitussin 9.6 4.6 (393) Buy on Amazon
16 Right Remedies Dextromethorphan HBr Cough Relief Softgels RIGHT REMEDIES 9.3 4.3 (111) Buy on Amazon
17 Cabinet Non-Drowsy Cough Relief Softgels Cabinet: 9.3 4.3 (501) Buy on Amazon
18 Strepsils Honey and Lemon Throat Lozenges Strepsils 8.0 4.6 (67) Buy on Amazon
19 Vicks NyQuil LiquiCaps Nighttime Cold and Flu Relief Vicks 0.0 0.0 Buy on Amazon
20 Alka-Seltzer Plus Severe Cold Effervescent Tablets ALKA-SELTZER PLUS 9.9 4.8 (1,813) Buy on Amazon
21 Alka-Seltzer Plus PowerMax Cold and Flu Day Gels ALKA-SELTZER PLUS 9.8 4.7 (1,160) Buy on Amazon
22 Vicks NyQuil Cold and Flu Nighttime Relief Liquid Capsules Vicks 9.8 4.8 (401) Buy on Amazon
23 HealthA2Z Nighttime Cold and Flu Relief Softgels HealthA2Z 9.7 4.7 (244) Buy on Amazon
24 Hyland's Naturals Baby Tiny Cold Day and Night Pack Hyland's 9.7 4.7 (164) Buy on Amazon
25 Mucinex Sinus-Max Day and Night Relief Pack Mucinex 7.9 4.7 (64) Buy on Amazon
26 Tylenol Cold and Flu Severe Symptom Relief Caplets Tylenol 7.4 4.1 (66) Buy on Amazon
27 XL-3 Xtreme Nighttime Cold and Flu Relief XL-3 6.9 4.4 (50) Buy on Amazon
28 Quality Choice Maximum Strength Flu HBP Medicine Quality Choice 5.1 4.3 (15) Buy on Amazon
29 Coricidin HBP Maximum Strength Cold and Flu Liquid Twinpack Coricidin HBP 0.0 0.0 Buy on Amazon
30 Tylenol Day and Night Cold and Flu Relief Combo Tylenol 0.0 0.0 Buy on Amazon