Best Vicks Cough Sore Throat Medicine in 2026

Daisy
Last Updated: Jul 20, 2026

At a Glance: Our Top Picks for Vicks Cough Sore Throat Medicine

Amazon Basic Care Daytime Cold & Flu Liquid, Orange Flavor, 8 Fluid Ounces
#TOP1
Amazon Basic Care Daytime Cold & Flu Liquid,
9.9
PM SCORE
Vicks NyQuil Cold and Flu Relief Liquid Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Sneezing, Runny Nose, and Cough, 48 Liquicaps
#TOP2
Vicks Nyquil Cold And Flu Relief Liquid Medicine,
9.9
PM SCORE
Tylenol Children's Cold + Flu Oral Suspension, Grape, 4 Fl. Oz
#TOP3
Tylenol Children's Cold + Flu Oral Suspension, Grape,
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Vicks Cough Sore Throat Medicine of 2026

Market Overview
Vicks Cough Sore Throat Medicine Reviewed
  • Reviews Analyzed: 136479 Items
  • PM Avg. Rating: 8.6 / 10
89 Products Evaluated
  • Highest Price: $59.99
  • Lowest Price: $4.47
  • Avg. Price: $16.20

Amazon Basic Care Daytime Cold & Flu Liquid, Orange Flavor, 8 Fluid Ounces

AMAZON BASIC CARE
0615190
2.18 X 2.25 X 6.48 Inches
0.67 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: This cold and flu medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant) which compare to the active ingredients in Vicks DayQuil Cold and Flu

MULTI-SYMPTOM RELIEF: Temporarily relieves headache, fever, sore throat, minor aches and pains, nasal congestion and cough due to the common cold and flu

NON-DROWSY: Each dose is designed for daytime use, so you can get through the day

MAXIMUM STRENGTH: When a cold or flu strikes, you need powerful relief

FOR AGES 6 AND OVER: For adults and children ages 6 and older; take as directed for cold and flu medicine that is alcohol, antihistamine and gluten free

Vicks Nyquil Cold And Flu Relief Liquid Medicine, Powerful Multi-Symptom Nighttime Relief For Headache, Fever, Sore Throat, Minor Aches And Pains, Sneezing, Runny Nose, And Cough, 48 Liquicaps

VICKS
2.00 X 3.32 X 4.32 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

FAST, POWERFUL MULTI-SYMPTOM RELIEF for your headache, fever, sore throat, minor aches and pains, sneezing, runny nose, and cough

EFFECTIVE NIGHTTIME COLD & FLU SYMPTOM RELIEF. NyQuil Cold & Flu Liquicaps temporarily relieves common cold & flu symptoms so you can get the rest you need

FAST RELIEF SO YOU CAN SLEEP. Don't let your cold keep you up. Just one dose of NyQuil starts working fast to provide effective cold & flu relief

POWER THROUGH YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil relieves bothersome symptoms such as cough and fever so that you can get the rest you need

WORLD'S #1 SELLING OTC COUGH AND COLD BRAND**. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms

Tylenol Children's Cold + Flu Oral Suspension, Grape, 4 Fl. Oz

TYLENOL
300450391056
1.97 X 1.97 X 5.13 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

4-fluid ounces of Children's Tylenol Oral Suspension Liquid Medicine with grape flavor to temporarily relieve kids' cold & flu symptoms, including cough, headache and fever

This multi-symptom relief medicine for kids also helps relieve minor aches and pains, sore throat, stuffy or runny nose, sneezing and congestion

Each 5mL contains 160 mg of acetaminophen pain reliever and fever reducer, 5 mg of dextromethorphan HBr cough suppressant, 2.5 mg of phenylephrine HCl decongestant and 1 mg of the antihistamine chlorpheniramine maleate

Indicated for children ages 6 to 11 years, this kids cold and flu medicine comes in a kid-friendly grape flavor with a formula that is free of aspirin, alcohol and ibuprofen

Tylenol is the #1 pediatrician recommended brand for pain & fever relief and has been relied on by parents for over 60 years.

Alka-Seltzer Plus Severe Night Cold Powerfast Fizz Effervescent Tablets, Lemon, 20 Count

ALKA-SELTZER PLUS
016500587590-VC
2.68 X 1.93 X 3.19 Inches
0.18 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Spintrex 7.81

Features

Our fantastic formula made even better: improved flavor, less sodium, & aspartame free

Our severe Cold night formula provides unbeatably liquid fast relief of headache, sore throat, cough, nasal congestion, sinus pressure & Congestion, runny nose, sneezing, Aches & pains and fever.

Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.

Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go

Comes in Effervescent form, with a refreshing lemon flavor. Use as directed.

Maximum Strength Mucinex Fastmax Dm Max & Mucinex Nightshift Cold & Flu Liquid (2 X 6 Fl. Oz.) Thins & Loosens Mucus, Relieves Cough & Chest Congestion, Pain, Fever, Sneezing, Sore Throat, Runny Nose

MUCINEX
1.44 X 5.01 X 5.77 Inches
1.00 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

POWERFUL MULTI-SYMPTOM RELIEF: This combo pack of Maximum Strength Mucinex Fast-Max DM Max and Nightshift Cold and Flu provides powerful multi-symptom relief for your worst symptoms

CHEST CONGESTION and COUGH SYMPTOM RELIEF: Maximum Strength Mucinex Fast-Max DM MAX relieves Chest Congestion, Controls Cough and Thins and Loosens Mucus

COLD and FLU SYMPTOM NIGHT RELIEF: Mucinex Nightshift Cold and Flu reduces Fever, relieves Headache, Minor Aches and Pains, Sore Throat, Coughing, Sneezing, Runny Nose for a better morning

TRUSTED COLD and COUGH BRAND: Mucinex is the Cold and Cough brand doctors trust and Pharmacist Recommended Brand

MUCINEX FAST-MAX DM MAX ACTIVE INGREDIENTS: Contains Dextromethorphan HBr - Cough suppressant; Guaifenesin – Expectorant

MUCINEX NIGHTSHIFT COLD and FLU ACTIVE INGREDIENTS: Contains Acetaminophen - Pain reliever and fever reducer; Dextromethorphan HBr - Cough suppressant; Triprolidine HCl – Antihistamine

USAGE: Use as directed; For ages 12 plus years

FSA and HSA ELIGIBLE: Save up to 30 percent. Cover your out-of-pocket expenses with pre-tax dollars.

#TOP6

Mucinex Fast-Max Day Time Cold & Flu And Night Time Cold & Flu Liquid Medicine, 12 Fl Oz, Maximum Strength All In One Multi Symptom Relief For Congestion, Sore Throat, Headache,Cough And Reduces Fever

MUCINEX
ASA-100
1.44 X 5.01 X 5.77 Inches
0.75 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
GREATPRICES4U 9.67

Features

MUCINEX FAST-MAX: Maximum strength multi-symptom relief medicine; 1 dose treats 9 symptoms - get back to what’s important thanks to the fast, powerful relief of Mucinex

DAY TIME SYMPTOMS TREATED: Maximum strength day time cold and flu non-drowsy liquid relieves cough, chest, nasal & sinus congestion that can cause mucus buildup, sinus pressure, fever, body pain & headache and sore throat

NIGHT TIME SYMPTOMS TREATED: Maximum strength night time cold and flu liquid relieves cough, nasal congestion that leads to stuffy nose, fever, body pain & headache, sneezing, runny nose and sore & itchy throat

DAY TIME ACTIVE INGREDIENTS per 20 mL: Acetaminophen - 650 mg pain reliever and fever reducer; Phenylephrine HCI - 10 mg nasal decongestant; Dextromethorphan HBr - 20 mg cough suppressant; Guaifenesin - 400 mg expectorant/thins and loosens mucus

NIGHT TIME ACTIVE INGREDIENTS per 20 mL: Acetaminophen - 650 mg pain reliever and fever reducer; Phenylephrine HCI - 10 mg nasal decongestant; Diphenhydramine HCI - 25 mg cough suppressant/antihistamine

FAST ACTING LIQUID: 2 bottles 6 fl oz each; adults and children 12 years of age and older, 20 ml in provided dosing cup every 4 hours

TRUST MUCINEX: Mucinex is the #1 Cold & Cough Brand Doctors Trust for Themselves & Their Families

FSA & HSA ELIGIBLE: Save up to 30%. Cover your out-of-pocket expenses with pre-tax dollars.

Vicks Dayquil And Nyquil Severe Cold & Flu Berry Liquid Medicine, Max Strength Relief For Headache, Fever, Sore Throat, Nasal Congestion, Cough, Combo Pack, 2 X 12 Oz Bottles, 1 Nyquil, 1 Dayquil

VICKS
323900017788
2.80 X 5.38 X 6.96 Inches
0.49 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
BabyLuck 9.25

Features

POWERFUL, MAXIMUM STRENGTH 9-SYMPTOM RELIEF: Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest

POWERFUL COLD & FLU RELIEF: DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms

NOTHING WORKS FASTER: Just one dose starts working fast to provide effective cold & flu relief

PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS: Life doesn’t stop when you have a cold, NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptoms taking you from 9 to none

WORLD'S #1 SELLING OTC COUGH AND COLD BRAND** Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms

Theraflu, Night Time Severe Cold And Cough Packets, 6 Count Packaging May Vary

THERAFLU
79180602
1.78 X 3.13 X 4.94 Inches
0.18 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

6 packets of Theraflu Nighttime Severe Cold Relief Honey Lemon Flavor Powder

Powerful relief from severe cold, cough, and flu symptoms such as sore throat pain, headache, minor body aches and pains, and nasal and sinus congestion

Hot liquid provides a soothing effect

Cold and cough medicine with delicious honey lemon, chamomile and white tea flavors

Can be taken every 4 hours, while symptoms persist. Do not take more than 5 packets in 24 hours unless directed by a doctor

Cold, flu, and cough relief powder for adults and children 12 years of age and over

Contains Acetaminophen 650 mg, Diphenhydramine HCl 25 mg, and Phenylephrine HCI 10 mg

HSA and FSA eligible product

Alka-Seltzer Plus Maximum Strength Cough, Mucus & Congestion Powermax Liquid Gels, 24 Count

ALKA-SELTZER PLUS
3.50 X 1.50 X 5.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

25% smaller than original liquid gel: Alka seltzer plus cold maximum strength cough, mucus & Congestion Powermax gels have a concentrated formula to provide powerful fast relief

Provides powerful maximum multi-symptom relief from nasal congestion, cough, headache, chest congestion, body ache, sore throat, Sinus pressure & Congestion and fever

Fast cold relief so you can get back to your busy life

Each box containing 24 Liquid gels, 1 dose (2 Liquid gels)

Use as directed

Cold & Cough, Mucinex Children's Multi-Symptom Day/Night Liquid, Very Berry, 4 Fl Oz (Pack Of 2)

MUCINEX
ASA-104
2.00 X 4.13 X 5.70 Inches
0.79 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

MULTI-SYMPTOM DAY TIME COLD RELIEF : Helps control cough, relieves stuffy nose, chest congestion and thins and loosens mucus

MULTI-SYMPTOM NIGHT TIME COLD RELIEF: Helps to reduce fever, control cough, relieves stuffy nose, runny nose, sneezing and sore throat

#1 PEDIATRICIAN RECOMMENDED: Mucinex Children’s is the #1 Pediatrician Recommended Brand among Non-Homeopathic Children’s Cough / Cold OTC products

ACTIVE INGREDIENTS DAY TIME MULTI-SYMPTOM COLD: Contains Dextromethorphan HBr for cough suppression, Guaifenesin as an expectorant and Phenylephrine HCl for nasal decongestion

ACTIVE INGREDIENTS NIGHT TIME MULTI-SYMPTOM COLD : Contains Acetaminophen as a pain reliever/fever reducer, Diphenhydramine HCI as an Antihistamine/Cough Suppressant and Phenylephrine HCl for nasal decongestion

FLAVOR: Available in Very Berry Flavor; Use as directed; Day Time ages 4 and up, Night time ages 6 and up

INSTRUCTIONS: Do not give the MUCINEX CHILDREN'S DAY TIME MULTI-SYMPTOM COLD and MUCINEX CHILDREN'S NIGHT TIME MULTI-SYMPTOM COLD liquids at the same time. Always wait at least 4 hours before giving another dose of MUCINEX CHILDREN'S LIQUID. Do not give more than a total of 5 doses in any 24-hour period.

Mucinex Maximum Strength Severe Congestion & Cough & Nightshift Cold & Flu Liquid For Multi-Symptom Relief, 6 Fl Oz (Pack Of 2)

MUCINEX
1.44 X 5.01 X 5.77 Inches
1.00 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

POWERFUL MULTI-SYMPTOM RELIEF: This combo pack of Maximum Strength Mucinex Fast Max Severe Congestion & Cough and NightShift Cold & Flu provides powerful multi-symptom relief for your worst symptoms

SEVERE CONGESTION & COUGH SYMPTOM RELIEF: Maximum Strength Mucinex Fast-Max Severe Congestion & Cough has a Triple Action Formula that relieves Nasal and Chest Congestion, Controls Cough and Thins & Loosens Mucus

COLD & FLU SYMPTOM NIGHT RELIEF: Mucinex Nightshift Cold & Flu reduces Fever, relieves Headache, Minor aches and Pains, Sore Throat, Coughing, Sneezing, Runny Nose for a better morning

#1 TRUSTED COLD & COUGH BRAND: Mucinex is the #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand

MUCINEX FAST-MAX SEVERE CONGESTION & COUGH ACTIVE INGREDIENTS: Contains Dextromethorphan HBr - Cough suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal decongestant

MUCINEX NIGHTSHIFT COLD & FLU ACTIVE INGREDIENTS: Contains Acetaminophen - Pain reliever and fever reducer; Dextromethorphan HBr - Cough suppressant; Triprolidine HCl – Antihistamine

USAGE: Use as directed; For ages 12+ years

FSA & HSA ELIGIBLE: Save up to 30%. Cover your out-of-pocket expenses with pre-tax dollars.

Congestion And Cough Liquid, Mucinex Fast-Max Severe Congestion And Cough Liquid, 6 Fl. Oz.(Package May Vary)

MUCINEX
6382401465
1.44 X 2.51 X 5.77 Inches
0.51 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

MAXIMUM STRENGTH RELIEF: Maximum Strength Mucinex Fast-Max Severe Congestion & Cough helps relieve cough, thins and loosens mucus and relieves chest and nasal congestion

#1 TRUSTED COLD & COUGH BRAND: Mucinex is the #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand

COUGH SUPPRESSANT: Contains Dextromethorphan HBr that helps relieve cough

EXPECTORANT: Contains Guaifenesin that thins and loosens mucus; relieves chest congestion

NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure

USAGE: Use as directed; For ages 12+ years

Cold Medicine For Kids Ages 2+ By Hyland's, Cold 'N Mucus Relief Liquid, Natural Relief Of Mucus & Congestion, Runny Nose, Cough, 4 Ounces

HYLAND'S
183503
5.63 X 2.77 X 2.92 Inches
0.25 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
JJBookIt 9.75

Features

RELIEF OF MUCUS & CONGESTION: Natural relief of symptoms of colds, including accumulation of mucus in chest, throat and nose: cough with expectoration of thick, discolored mucus; runny nose, sneezing and nasal congestion. Safe for ages 2-12

EASY TO TAKE: Natural syrup to ease mucus & congestion, runny nose and cough

4 FL OZ= UP TO 23 DOSES of Hyland's 4 Kids Cold 'n Mucus

SAFE AND NON-HABIT FORMING: Our gentle homeopathic formulas are made with all natural active ingredients. There are no known side-effects and will not conflict with any medications you may be taking

Safe, Effective, Natural Formula for children 2-12 years old

All natural homeopathic ingredients

Contains no Aspirin, Acetaminophen, Ibuprofen, Naproxen, Pseudoephedrine or Dextromethorphan

Sugar Free, Dye Free

No artificial flavors

Safe, Effective, Natural Formula for children 2-12 years old

Multi-symptom, natural relief without sleepy or stimulant side effects

Contains no Aspirin, Acetaminophen, Ibuprofen, Naproxen, Pseudoephedrine or Dextromethorphan

Sugar Free, Dye Free

No artificial flavors

Goodsense Nighttime Cold And Flu Relief, Cherry Flavor, Cold And Flu Liquid, 12 Fl Oz (Pack Of 1)

GOODSENSE
301130459400
2.50 X 2.50 X 7.25 Inches
1.05 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

EFFECTIVE: Compare GoodSense Nighttime Cold and Flu Relief Liquid to the active ingredients of NyQuil Cold & Flu. The active ingredients of this cold and flu relief liquid are Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, and Doxylamine succinate 12.5 mg. They all combine to create an effective cold and flu medicine

COLD AND FLU MEDICINE: GoodSense Nighttime Cold and Flu Relief provides multi-symptom relief by helping with common symptoms such as aches, fever, cough, sneezing and runny nose

NIGHTTIME COLD AND FLU RELIEF: GoodSense Nighttime Cold and Flu Relief provides through the night cold care. This cold remedy relieves cold and flu symptoms so you can rest. Does not contain Pseudoephedrine; contains 10% Alcohol.

COLD AND FLU RELIEF LIQUID: This liquid pain reliever, fever reducer, cough suppressant, antihistamine is cherry flavored.

IDENTIFYING the COMMON COLD: A cold usually includes a runny nose, sore throat, sneezing, and coughing. To protect yourself from common cold wash your hands often with soap and water.

Alka Seltzer Plus Severe Non-Drowsy Cold & Cough Powerfast Fizz Effervescent Common Cold Tablets, Sinus Congestion, Runny Nose, And Dry Cough, Citrus Flavor, 20 Count (Pack Of 1)

ALKA-SELTZER PLUS
016500587620-VC
2.68 X 1.93 X 3.19 Inches
0.17 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
MASKU LLC 9.65

Features

ALKA-SELTZER PLUS Severe Non-Drowsy Cold & Cough PowerFast Fizz Effervescent Tablets is a cold remedy for adults, with less sodium, improved flavor, and aspartame free.

Our severe Cold & Cough formula provides unbeatably liquid fast cold relief of headache, sore throat, cough, nasal & sinus congestion, runny nose, sneezing, aches, pains, fever and other severe cold symptoms.

Also acting as a cough suppressor and dry cough medicine, the non-drowsy formula allows individuals to stay alert and productive while battling cold symptoms.

Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes this cold remedy for adults easy to take with you on the go

The cold tablets are designed to dissolve quickly in water, creating a refreshing and effervescent citrus-flavored drink while tackling your severe cold & cough symptoms.

Alka-Seltzer Plus Cold & Flu, Power Max Cold And Flu Medicine, Day, For Adults With Pain Reliver/Fever Reducer, Cough Suppressant, Nasal Decongestant, 24 Count

ALKA-SELTZER PLUS
I00104723
3.50 X 1.50 X 0.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Hammond K&T 9.12

Features

NEW 25 percent smaller pill: Alka Seltzer Plus Maximum Strength Cold & Flu PowerMax Gels have a concentrated formula in a smaller liquid gel so it's easier to swallow

Provides up to 4 hours of relief: one dose provides 4 hour day time relief of cough, nasal congestion, headache & body ache, sore throat, and sinus pressure

Alka Seltzer Plus Maximum Strength Cold & Flu PowerMax Gels contain a pain reliever, fever reducer, cough suppressant, and nasal decongestant

Temporarily relieves these symptoms due to a cold or flu: Minor aches and pains, cough, headache, sore throat, & nasal and sinus congestion. Temporarily reduces fever

PowerMax Gels do not have to be taken with meals

Robitussin Maximum Strength Severe Nighttime Multi-Symptom Cough, Cold And Flu Medicine, Nighttime Cf Max, Raspberry Flavor - 4 Fl Oz Bottle

ROBITUSSIN
PF75212
2.00 X 2.00 X 5.00 Inches
0.25 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

One 4 fl oz bottle of Robitussin Maximum Strength Severe Nighttime Multi-Symptom Cough, Cold and Flu Medicine, Nighttime CF Max, Raspberry Flavor

Robitussin multi symptom nighttime cold medicine provides multi symptom relief and acts as a nasal decongestant

Quick and easy-to-use liquid cough suppressant formula contains no dextromethorphan and has acetaminophen, a fever reducer and pain reliever. Health Concern: Cold Flu Cough

Raspberry flavored cough and cold medicine for pain and temporary nasal congestion relief

Robitussin nighttime cold and flu formula helps you get a good night's sleep

Robitussin maximum strength severe multi symptom relief for adults and children 12 years and over, not for use in children under 12 years

Take 20 mL of this cold and flu remedy for adults and children 12 years and over every 4 hours for temporary multi symptom severe congestion relief

Do not take more than 6 doses in any 24 hour period

HSA and FSA eligible product

Valumeds Nighttime Cough Plus Cold And Flu Relief Medicine | 48 Pack Softgel Liquid Capsules | Helps Relieve Sore Throat, Fever, Headaches, Runny Nose, Aches

VALUMEDS
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
ValuMeds 9.90

Features

Powerful Nighttime Relief: ValuMeds Nighttime Cough Plus Cold and Flu Relief Medicine is specifically formulated to provide effective relief from cough, cold, and flu symptoms during the night. Say goodbye to sleepless nights and wake up feeling refreshed.

Comprehensive Cold and Flu Relief: Our medicine combines the power of a cough suppressant, cold, and flu relief to provide you with comprehensive symptom relief. From coughing and congestion to sore throat and sinus pressure, our formula targets multiple symptoms to help you feel better.

Trusted Brand for Adults: Trust in our brand's expertise in cold and flu relief. Our Nighttime Cough Plus Cold and Flu Relief Medicine is suitable for adults and is comparable to leading brands like Nyquil and Dayquil. Experience the same quality and effectiveness at a more affordable price.

Convenient Pack: Our pack contains all the necessary doses to get you through the night. Each pack includes the perfect combination of nighttime relief and sleep aid to ensure you get the restful sleep you need to recover from cold and flu symptoms.

Use as Directed: ValuMeds Nighttime Cold and Flu gels should always be used as directed. Please read package for more details on proper use and dosage for children and adults.

Vicks Nyquil Cold And Flu Nighttime Relief Liquid Capsules, 16 Count

VICKS
604959
1.06 X 1.06 X 3.25 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Temporarily relieves common cold and flu symptoms including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing.

Mucinex® Nightshift® Cold & Flu Liquid 9 Fl. Oz. Relieves Fever, Sneezing, Sore Throat, Runny Nose, And Controls Cough

MUCINEX
1.46 X 2.95 X 6.30 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

#1 TRUSTED COLD & COUGH BRAND: Mucinex is the #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand

Tukol Children's Cough & Cold Medicine, Nasal Decongestant, Cough Suppressant & Chest Congestion Relief, Fast Acting, Non-Drowsy Syrup, 4 Fl Oz

TUKOL
GEN00539
2.00 X 2.00 X 5.13 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Cough and Cold Syrup for Kids: This non-drowsy medication provides powerful cold symptom relief, working as an expectorant and decongestant to relieve nasal congestion while suppressing coughs due to minor throat and bronchial irritation

Children's Formula: Specially formulated for children 4 and over, this non-drowsy syrup starts working fast to bring your child relief, featuring a pleasant grape flavor that kids love

Multi-Symptom Treatment: Whether you're dealing with congestion, cold, flu, sore throat or a persistent cough, we've got the remedy for you, available in daytime or nighttime formulas for children or adults

Tukol Relief: We make an array of products for the relief of cough, cold, sore throat, fever and flu, for children and adults; Try our liquid cough suppressants, decongestants and sore throat syrups

Theraflu Max Strength Daytime Flu Symptom Relief, Honey And Elderberry Syrup, 8.3 Fl Oz And Nighttime Flu Symptom Relief, Honey Lemon - 6 Count

THERAFLU
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

One 8.3 fl oz bottle of Theraflu Max Strength (1) Daytime Flu Symptom Relief, Honey and Elderberry Flavored Syrup plus 6 powder packets of Theraflu Max Strength (1) Nighttime Flu Symptom Relief

Powerful relief from flu symptoms such as sore throat pain, headache, body aches and pains, cough and fever

Theraflu flu symptom relief syrup is easy to take

Each dose of daytime syrup contains acetaminophen 1,000 mg and dextromethorphan HBr 30 mg

Each nighttime packet contains acetaminophen 1,000 mg, dextromethorphan HBr 30 mg and chlorpheniramine maleate 4 mg

Adults and children ages 12 and older take this flu symptom relief liquid every six hours as needed for symptom relief. Do not take more than 3 doses in 24 hours unless directed by a doctor

Vick Nyquil Cough Cold And Flu Nighttime Relief, Original Liquid, 2X12 Fl Oz

VICKS
323900014299
2.75 X 5.25 X 6.85 Inches
1.82 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Enterprise Driven 7.68

Features

Temporarily relieves common cold and flu symptoms including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing

NyQuil Liquid is available in three flavors: Original, cherry and vanilla cherry swirl

When using DayQuil or NyQuil products, carefully read each label to ensure correct dosing

Use as directed. Keep out of reach of children

Keep out of reach of children

Tylenol Cold + Flu + Cough Night Liquid Medicine With Acetaminophen, Wild Berry, Grabe, 8 Fl Oz

TYLENOL
JO305620800
2.00 X 3.00 X 5.25 Inches
0.66 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
OTCRx4u 9.93

Features

8-fluid ounce bottle of Tylenol Cold + Flu + Cough Night Liquid medicine in Wild Berry Burst flavor for multi-symptom relief due to cold & flu

This liquid cold & flu relief medicine comes in a nighttime formula and provides temporary relief of symptoms including fever, sore throat, nasal congestion and cough to help you sleep

Each 15-milliliter contains 325 milligrams of acetaminophen, a pain reliever and fever reducer and 10 milligrams dextromethorphan HBr to help suppress your cough

Each 15-milliliter also contains 5 milligrams of phenylephrine HCl, a nasal decongestant and 6.25 milligrams of doxylamine succinate, an antihistamine

The triple-action nighttime cold and flu medicine for adults provides temporary relief of multiple symptoms and features a Wild Berry Burst flavor

Nature's Way Umcka Coldcare Drops, Sore Throat, Cough, And Congestion, Alcohol Free, Cherry Flavored Drops, 2 Fl. Oz

NATURE'S WAY
033674157916
6.00 X 5.00 X 4.00 Inches
0.30 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Homeopathic - Shortens the duration and reduces severity of common cold, nasal, throat and bronchial irritations.

Pelargonium sidoides (EPs 7630) 1X – the main ingredient in Umcka ColdCare – works with the immune system to help support the body’s own defense mechanisms.

That means you’re getting a medicine that works safely with your body – not against it.

Umcka ColdCare 99.9% Alcohol-Free Drops come in a concentrated liquid form with droppers for convenient dosage

You can take it straight or add it to a beverage – whatever is more convenient for you. This 99.9% alcohol-free formula is safe for ages 6 and up. Umcka ColdCare Drops are also available in an original formula

Valumeds Adult Cough Relief For Adults Dextromethorphan Hbr 15Mg (60 Softgels) 8-Hour, Non-Drowsy, Long-Lasting Bronchial Suppressant

VALUMEDS
64744-6
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
ValuMeds 9.90

Features

Stop Coughing Fast – Perfect for wet or dry cough relief these cough suppression softgels provide up to 8 hours of continuous relief with fast-acting results.

Non-Drowsy Day Time Relief – The smart choice for when you can’t miss work, school, or an important event, our cold cough relief provides non-drowsy support.

Help Reduce the Urge – Formulated with Dextromethorphan HBr this cough suppressant can reduce the “tickle” in your airways to allow for deeper breathing.

Easy-to-Swallow Softgels – Easier to take than ill-tasting liquids or dry pills our softgels help reach your digestive system to start working faster and efficiently.

Focused Adult Support – ValuMeds Cough Relief is for children and adults ages 12 and up. Please follow the directions closely to ensure proper safety and use.

#TOP27

Diabetic Tussin Nighttime Cold And Flu Medicine - 4 Fl Oz - Sugar Free Liquid Cough Syrup, Safe For Diabetics, Berry Flavored

DIABETIC TUSSIN
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Safe & sugar free: Diabetic Tussin Nighttime is a sugar-free nighttime cold and flu medicine that is safe for people with diabetes.

Cold and flu symptom relief: This product can be taken for minor aches & pains, runny nose & sneezing, headache relief, and sore throat relief

Formulated to be effective for all: This product is formulated with diabetic individuals in mind but can also be effectively used by anyone needing effective cold and flu symptom relief while being conscious of sugar intake.

The Diabetic Tussin Difference: Diabetic Tussin is a cough suppressant, pain reliever and antihistamine that is formulated without sugar, alcohol, aspartame, sodium, sorbitol, fructose, gluten or dyes.

Dosing: Adults should take 10mL per serving (2 teaspoons) and shouldn’t exceed 6 doses per 24 hours. 11- 12 servings per bottle.

Mucinex Nightshift Cold & Flu Liquid That Relieves Fever/Sneezing/Sore Throat/Runny Nose And Cough, 6 Fl Oz (Pack Of 1)

MUCINEX
6382401470
1.44 X 2.51 X 5.77 inches
0.48 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
BRANDO-787 6.24

Features

#1 TRUSTED COLD & COUGH BRAND: Mucinex is the #1 Cold and Cough brand doctors trust*

Mucinex Freefrom Cold & Flu Daytime, Multi-Symptom Relief, Cherry, 6 Fl Oz

MUCINEX
1.44 X 2.51 X 5.77 Inches
0.48 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Premium Possibilities 9.88

Features

MULTI-SYMPTOM COLD & FLU RELIEF: FreeFrom Cold and Flu Daytime liquid helps reduce fever and relieve Cough, Sore Throat, Stuffy Nose, Chest & Nasal Congestion, Headache and Minor Aches and Pains

FREE FROM UNWANTED ADDITIVES: No Artificial flavors, Colors, Dyes; Free from Alcohol and Sugar

#1 TRUSTED COLD & COUGH BRAND: Mucinex is the #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand

PAIN RELIEVER & FEVER REDUCER: Contains Acetaminophen which relieves minor aches and pains thereby relieving your sore throat pain and reduces fever

COUGH SUPPRESSANT: Contains Dextromethorphan HBr that helps relieve cough

EXPECTORANT: Contains Guaifenesin that thins and loosens mucus; relieves chest congestion

NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure

FLAVOR: Available in Elderberry & Cherry Natural flavor

Mucinex Children's Liquid - Freefrom Multi-Symptom Cold, Flu & Sore Throat 4Oz, 1 Pack

MUCINEX
0.40 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

MULTI-SYMPTOM COLD, FLU & SORE THROAT RELIEF: Mucinex Children’s FreeFrom Multi-Symptom Cold, Flu & Sore Throat helps relieve cold and flu symptoms: cough, sore throat, stuffy nose, chest & nasal congestion, headache and reduces fever

FREE FROM UNWANTED ADDITIVES: Free from unwanted additives such as artificial flavors, colors, dyes; No alcohol and sugar

#1 PEDIATRICIAN RECOMMENDED: Mucinex Children’s is the #1 Pediatrician Recommended Brand among Non-Homeopathic Children’s Cough / Cold OTC products

PAIN RELIEVER & FEVER REDUCER: Contains Acetaminophen which relieves pain, reduces fever and help relieve your sore throat symptoms

COUGH SUPPRESSANT: Contains Dextromethorphan HBr that helps relieve cough

EXPECTORANT: Contains Guaifenesin that thins and loosens mucus; relieves chest congestion

NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure​

FLAVOR: Available in Elderberry & Cherry Natural Flavor; Use as directed; For ages 6+ years​

Top 10 cough sore throat medicine Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Mucinex 23
Vicks 19
Amazon Basic Care 9
Alka-Seltzer Plus 7
Tylenol 5
Tukol 4
Hyland's 3
Theraflu 3
Coricidin Hbp 2
Valumeds 2

Top 10 cough sore throat medicine Brands Pie Chart


We've carried out a comprehensive analysis of 136,479 reviews on cough sore throat medicine, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select cough sore throat medicine priced around $16.20, with top brands including mucinex, boiron, chloraseptic, vicks, theraflu, alka-seltzer plus, robitussin, hyland's and sucrets and ricola

Our team of expert editors reviewed these high-quality items and handpicked the top 30 cough sore throat medicine for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, nc commercial, greatprices4u, bnt distributor, incredible designs llc, name brand overstock, healthy products a plus llc, the customer land and beekeeper's naturals and focus health .

We are dedicated to assisting our users in finding the right medicine Products based on their needs, saving them considerable time when choosing which cough sore throat medicine to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.