Best Vicks Cough Sore Throat Medicine in 2026

Daisy
Last Updated: Jul 20, 2026

At a Glance: Our Top Picks for Vicks Cough Sore Throat Medicine

Vicks DayQuil and NyQuil SEVERE Combo, Cold & Flu Medicine, Max Strength Relief For Fever, Sore Throat, Nasal Congestion, Sinus Pressure, Stuffy Nose, Cough, 48 Count, 32 DayQuil, 16 NyQuil
#TOP1
Vicks Dayquil And Nyquil Severe Combo, Cold &
10.0
PM SCORE
Amazon Basic Care Cold & Flu Relief Multi-Symptom Daytime/Nighttime Combo Pack Softgels, 48 Count
#TOP2
Amazon Basic Care Cold & Flu Relief Multi-Symptom
9.9
PM SCORE
Vicks NyQuil Cold and Flu Relief Liquid Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Sneezing, Runny Nose, and Cough, 48 Liquicaps
#TOP3
Vicks Nyquil Cold And Flu Relief Liquid Medicine,
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Vicks Cough Sore Throat Medicine of 2026

Vicks Dayquil And Nyquil Severe Combo, Cold & Flu Medicine, Max Strength Relief For Fever, Sore Throat, Nasal Congestion, Sinus Pressure, Stuffy Nose, Cough, 48 Count, 32 Dayquil, 16 Nyquil

VICKS
53-PVRZ-0FPE
2.00 X 4.31 X 3.31 Inches
0.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

POWERFUL, MAXIMUM STRENGTH 9-SYMPTOM RELIEF: Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest

POWERFUL COLD & FLU RELIEF: DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms

NOTHING WORKS FASTER: Just one dose starts working fast to provide effective cold & flu relief

PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS: Life doesn’t stop when you have a cold, NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptoms taking you from 9 to none

WORLD'S #1 SELLING OTC COUGH AND COLD BRAND** Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms

Amazon Basic Care Cold & Flu Relief Multi-Symptom Daytime/Nighttime Combo Pack Softgels, 48 Count

AMAZON BASIC CARE
58072
4.38 X 2.00 X 3.25 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Cold & Flu and Vicks NyQuil Cold & Flu

NON-DROWSY DAYTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains

NIGHTTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains

PAIN RELIEVER AND FEVER REDUCER: Both Daytime and Nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat

COLD AND FLU: Influenza (flu) and the common cold are respiratory illnesses caused by viruses. A cold medicine like Cold & Flu Relief Multi-Symptom Daytime/Nighttime can help

Vicks Nyquil Cold And Flu Relief Liquid Medicine, Powerful Multi-Symptom Nighttime Relief For Headache, Fever, Sore Throat, Minor Aches And Pains, Sneezing, Runny Nose, And Cough, 48 Liquicaps

VICKS
2.00 X 3.32 X 4.32 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

FAST, POWERFUL MULTI-SYMPTOM RELIEF for your headache, fever, sore throat, minor aches and pains, sneezing, runny nose, and cough

EFFECTIVE NIGHTTIME COLD & FLU SYMPTOM RELIEF. NyQuil Cold & Flu Liquicaps temporarily relieves common cold & flu symptoms so you can get the rest you need

FAST RELIEF SO YOU CAN SLEEP. Don't let your cold keep you up. Just one dose of NyQuil starts working fast to provide effective cold & flu relief

POWER THROUGH YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil relieves bothersome symptoms such as cough and fever so that you can get the rest you need

WORLD'S #1 SELLING OTC COUGH AND COLD BRAND**. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms

Vicks Vaposhower Plus, Shower Bomb Tablet, Extra Strong Soothing Vapor, Dayquil & Nyquil Liquicaps, Cough, Cold, Flu, Sore Throat, Fever & Congestion, 72 Liquicaps (48 Dayquil, 24 Nyquil)

VICKS
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

FROM THE TRUSTED EXPERTS AT VICKS: Feel like yourself again with this Vicks Day and Night bundle. Bundle contains one pack of Vicks VapoShower PLUS (12 tablets) and one pack each of DayQuil and NyQuil LiquiCaps

TRANSFORM YOUR SHOWER WITH VICKS VAPOSHOWER PLUS. Vicks VapoShower PLUS tablets transform your shower into a Vicks Vapors Sauna by infusing with shower steam and soothing with extra strong Vicks aromatherapy vapors

VAPOSHOWER PLUS IS EASY TO USE & DISSOLVES CLEANLY. Vicks VapoShower PLUS leaves no residue and won’t stain your shower. Easy to use - just place on shower floor in direct stream of hot or warm water and continue running shower until completely dissolved

POWERFUL COLD SYMPTOM RELIEF, DAY OR NIGHT. Get powerful 6-symptom relief with DayQuil & NyQuil LiquiCaps

MULTI-SYMPTOM RELIEF from the World's #1 Selling Cough & Cold Brand. Vicks NyQui is the nighttime, sniffling, sneezing, coughing, aching, stuffy head, fever, BEST SLEEP WITH A COLD, medicine. Vicks DayQuil is the daytime, coughing, sneezing, aching, stuffy head, fever, sore throat, congested chest, POWER THROUGH YOUR DAY, medicine.

Vicks, Vapocool Severe Medicated Drops 18Ct Maximumstrength Relief To Soothe Sore Throat Pain, Menthole, 18 Count

VICKS
0.85 X 4.50 X 7.70 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
The Customer Land 9.69

Features

FAST SORE THROAT RELIEF THAT STARTS WORKING IN SECONDS: Simply let the Vicks VapoCOOL drop dissolve in your mouth for a powerful rush of Vicks Vapors

MAXIMUM STRENGTH RELIEF. Vicks VapoCOOL SEVERE provides powerful relief with a rush of trusted Vicks Vapors.

VAPORIZE SORE THROAT PAIN: When you need something powerful that will knock out the pain right where you need it

IT'S NOT CANDY…IT'S POWERFUL RELIEF. Each drop contains 20mg menthol to soothe sore throats.

DELIGHTFUL WINTERFROST FLAVOR. Enjoy the cool winterfrost flavor. For more sore throat relief, also try Vicks VapoCOOL Lozenges and Sore Throat Spray in Winterfrost flavor.

Vicks Nyquil Cold And Flu Nighttime Relief Liquid Capsules, 16 Count

VICKS
604959
1.06 X 1.06 X 3.25 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Temporarily relieves common cold and flu symptoms including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing.

Healtha2Z Daytime Cold & Flu Relief - Non Drowsy | 20 Count Softgels | Compare To Vicks® Dayquil® Cold & Flu Liqui Caps Active Ingredient

HEALTHA2Z
FP0692
4.33 X 1.16 X 3.50 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
HealthA2Z 9.95

Features

Compare to VicksDayquil Cold & Flu LiquiCaps / Each softgel contains Acetaminophen 325mg,Dextromethorphan HBr 10mg, Phenylephrine HCl 5mg.

Relieves common cold and flu symptoms / nasal congestion / sore throat / headache / fever reducer / Pain reliver / cough due to minor throat and bronchial irriation.

Our small and compact packages are light weight and can easily fit in your purse, luggage, glove compartment, etc! The perfect mobile solution to keep you healthy and enhance your travel experience!

Vick Nyquil Cough Cold And Flu Nighttime Relief, Original Liquid, 2X12 Fl Oz

VICKS
323900014299
2.75 X 5.25 X 6.85 Inches
1.82 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Enterprise Driven 7.68

Features

Temporarily relieves common cold and flu symptoms including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing

NyQuil Liquid is available in three flavors: Original, cherry and vanilla cherry swirl

When using DayQuil or NyQuil products, carefully read each label to ensure correct dosing

Use as directed. Keep out of reach of children

Keep out of reach of children

Goodsense Nighttime Cold & Flu Relief, Pain Reliever, Fever Reducer, Cough Suppressant & Antihistamine, 8 Fluid Ounces Green

GOODSENSE
33534
2.18 X 2.25 X 6.48 Inches
0.67 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Vitabox 9.88

Features

ACTIVE INGREDIENTS: This product contains acetaminophen (pain reliever and fever reducer), dextromethorphan HBr (cough suppressant) and doxylamine succinate (antihistamine) which compares to the active ingredients in Vicks NyQuil Cold & Flu

POWERFUL NIGHTTIME RELIEF: This cold and flu medicine provides multi-symptom relief of common cold and flu symptoms while you sleep

PAIN RELIEVER AND FEVER REDUCER: Relieves sore throat, minor aches and pains and reduces fever associated with the common cold and flu

COUGH SUPPRESSANT: This nighttime cold and flu relief medicine helps to relieve coughing so you can rest

ANTIHISTAMINE: Helps relieve runny nose and sneezing associated with the common cold and flu

Vicks Children's Multi-Symptom Cold Relief From Cough, Sore Throat, Fever; Free Of: Artificial Dyes & Flavors, High Fructose Corn Syrup & Alcohol, Citrus Orange Flavor, For Children Ages 6+, 6 Fl Oz

VICKS
B07QSBY91J
1.69 X 2.17 X 5.79 Inches
0.42 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Durr's Outlet 9.67

Features

MULTI-SYMPTOM COLD RELIEF FROM COUGH, SORE THROAT AND FEVER: Provides fast relief of aches, fever, sore throat, cough, and stuffy nose. Effective for up to 4 hours

SIMPLE, EFFECTIVE RELIEF: Specially formulated to be free of artificial dyes and flavors, high fructose corn syrup, and alcohol

DESIGNED FOR CHILDREN: Vicks Children's Multi-Symptom Cold Relief is designed to have a great-tasting, citrus flavor your child will love

PAIN RELIEVER, FEVER REDUCER, COUGH SUPPRESSANT AND DECONGESTANT: Contains Acetaminophen, Dextromethorphan HBr, and Phenylephrine HCI

FORMULATED FOR CHILDREN AGES 6+

Vicks Nyquil Nighttime Cherry, 8 Fl Oz (Old Version)

VICKS
01271393
2.30 X 2.20 X 6.35 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Essex Distribution 9.19

Features

Temporarily relieves common cold and flu symptoms including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing

Nyquil liquid is available in three flavors original, cherry and vanilla cherry swirl

When using Dayquil or Nyquil products, carefully read each label to insure correct dosing use as directed keep out of reach of children

Nyquil Liquid Cherry 8 Oz

VICKS
6.00 X 6.00 X 10.00 Inches
0.50 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
sweeteddy 9.19

Features

Vicks Cold & Flu, Nighttime Relief, 8 oz

Vicks NyQuil, Nighttime Cold & Flu Symptom Relief, Relives Aches, Fever, Sore Throat, Sneezing, Runny Nose, Cough, 8 Fl OZ, Cherry Flavor

Top 10 cough sore throat medicine Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Vicks 45
Amazon Basic Care 14
Healtha2Z 2
Goodsense 1

Top 10 cough sore throat medicine Brands Pie Chart


We've carried out a comprehensive analysis of 176,177 reviews on cough sore throat medicine, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select cough sore throat medicine priced around $15.86, with top brands including mucinex, boiron, chloraseptic, vicks, theraflu, alka-seltzer plus, robitussin, hyland's and sucrets and ricola

Our team of expert editors reviewed these high-quality items and handpicked the top 12 cough sore throat medicine for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, nc commercial, greatprices4u, bnt distributor, incredible designs llc, name brand overstock, healthy products a plus llc, the customer land and beekeeper's naturals and focus health .

We are dedicated to assisting our users in finding the right medicine Products based on their needs, saving them considerable time when choosing which cough sore throat medicine to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.