Best Caplet Flu Medicine in 2026

ACTIVE INGREDIENTS: This product contains acetaminophen (pain reliever and fever reducer), dextromethorphan HBr (cough suppressant) and doxylamine succinate (antihistamine) which compares to the active ingredients in Vicks NyQuil Cold & Flu.

POWERFUL NIGHTTIME RELIEF: This cold and flu medicine provides multi-symptom relief of common cold and flu symptoms while you sleep.

PAIN RELIEVER AND FEVER REDUCER: Relieves sore throat, minor aches and pains and reduces fever associated with the common cold and flu.

FROM THE TRUSTED EXPERTS AT VICKS: Feel like yourself again with this Vicks Day and Night bundle. Bundle contains one pack of Vicks VapoShower PLUS (12 tablets) and one pack each of DayQuil and NyQuil LiquiCaps

TRANSFORM YOUR SHOWER WITH VICKS VAPOSHOWER PLUS. Vicks VapoShower PLUS tablets transform your shower into a Vicks Vapors Sauna by infusing with shower steam and soothing with extra strong Vicks aromatherapy vapors

VAPOSHOWER PLUS IS EASY TO USE & DISSOLVES CLEANLY. Vicks VapoShower PLUS leaves no residue and won’t stain your shower. Easy to use - just place on shower floor in direct stream of hot or warm water and continue running shower until completely dissolved

MUCINEX CHEST CONGESTION MEDICINE: Clinically proven to last up to 12 hours and provide relief for your chest congestion and make cough more productive

POWERFUL SYMPTOM RELIEF: Mucinex 12 hour relieves chest congestion and thins and loosens mucus

BI-LAYER TABLET: A unique bi-layer tablet, one layer for immediate release and one layer for extended release so the medicine starts to release right away and last for up to 12 hours

Helps relieve pain, headache, nasal congestion, sinus congestion and chest congestion

Thins & loosens mucus with active ingredient guaifenesin expectorant

Relieves headache pain with active ingredient acetaminophen pain relievers and fever reducers

MUCINEX CHEST CONGESTION MEDICINE: Clinically proven to last up to 12 hours and provide relief for your chest congestion and make cough more productive

POWERFUL SYMPTOM RELIEF: Mucinex 12 hour relieves chest congestion and thins and loosens mucus

BI-LAYER TABLET: A unique bi-layer tablet, one layer for immediate release and one layer for extended release so the medicine starts to release right away and last for up to 12 hours

NIGHTTIME RELIEF FOR A BETTER MORNING: Get Powerful Nighttime Cold & Flu Multi-Symptom Relief with Maximum Strength Mucinex NightShift Cold & Flu fast release caplets. Relieves Headache, Body Pain, Cough, Sneezing, Runny Nose, and Reduces Fever so you can get to sleep.

#1 TRUSTED COLD & COUGH BRAND: Mucinex is the #1 Cold and Cough brand doctors trust*

ACTIVE INGREDIENTS PER CAPLET: Contains Acetaminophen (325 mg) - Pain reliever and Fever reducer; Dextromethorphan HBr (10 mg) - Cough Suppressant; Triprolidine HCI (1.25 mg) - Antihistamine.

Relieve Cold & Flu Symptoms: For use as a cough suppressant, pain reliever, and nasal decongestant. Our daytime cold and flu medicine combats the toughest colds, fast!

Power Through the Day: This cough medicine is a non-drowsy cold and sinus formula that allows you to stay focused and alert while on the go at home, work, or school.

Relieve Joint & Muscle Aches: Extra strength acetaminophen in our formula helps reduce fevers, aches and pains, for adults experiencing even the most severe cold and cough symptoms.

MAX STRENGTH: Maximum Strength, Multi-Symptom Cold + Flu Relief

SYMPTOM RELIEF: Contac Cold + Flu Day caplets provide symptom relief for Nasal Congestion, Sinus Pressure, Sore Throat, Head & Minor Body Aches, and Fever.

NON-DROWSY: Contac Cold + Flu Day provides multi-symptom relief in a non-drowsy caplet.

20-count of Sudafed PE Non-Drowsy Head Congestion + Pain Relief Caplets for effective nasal congestion relief and nasal swelling relief, now coupled with the powerful pain relief of ibuprofen

From the #1 pharmacist recommended brand among oral OTC decongestants, it provides non-drowsy relief from head congestion and pain symptoms caused by head colds

Each coated caplet contains 200 milligrams of ibuprofen, the #1 doctor-recommended pain reliever, to help reduce fever while also helping to alleviate headache and minor body aches and pains

Our fantastic formula made even better: Improved flavor, less sodium and aspartame free

Our severe Cold and Flu formula provides unbeatably liquid fast relief of headache, sore throat, cough, nasal and sinus congestion, runny nose, sneezing, Aches, pains and fever.

Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.

MULTI-SYMPTOM RELIEF: Mucinex Children’s Cough & Congestion helps control cough, thins and loosens mucus, relieves chest congestion and stuffy nose

#1 PEDIATRICIAN RECOMMENDED: Mucinex Children’s is the #1 Pediatrician Recommended Brand among Non-Homeopathic Children’s Cough / Cold OTC products

COUGH SUPPRESSANT: Contains Dextromethorphan HBr which helps control cough

24-count of Tylenol Cold Max non-drowsy cold and flu medicine with acetaminophen for multi-symptom relief

Medicine provides temporary relief for cold and flu symptoms including aches and pains, sore throat, nasal congestion, sinus congestion and pressure, cough and fever

Each cold & flu caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains

24-count of Tylenol Sinus Severe Daytime Caplets for non-drowsy symptom relief due to the common cold, hay fever or other respiratory allergies

Pain reliever, decongestant and expectorant to temporarily relieve symptoms of chest congestion, nasal congestion, sinus headache and pressure

Each caplet contains 325 mg of acetaminophen to temporarily relieve pain and reduce fever; 5 mg of nasal decongestant phenylephrine HCl to help clear nasal passages; and 200 mg of the expectorant guaifenesin to help make coughs more productive

Qty is 3 pk, Tylenol Sinus Congestion and Pain Severe - 24 Caplets

Temporarily relieves these symptoms associated with hay fever or other respiratory allergies, and the common cold: sinus congestion and pressure; headache; nasal congestion; minor aches and pains.

24 Caplets per-pk

The information below is per-pack only

Temporarily relieves common cold and flu symptoms including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing.

✅ ACTIVE INGREDIENT: The active ingredient in this product is Guaifenesin, an expectorant that helps reduce chest congestion caused by colds, infections or irritants. Clinically proven to provide powerful relief for your toughest chest congestion. Compare Safrel Mucus Relief to the active ingredient of Mucinex.

✅ FAST ACTING: Safrel Mucus Relief Guaifenesin is a fast-acting expectorant helps loosen and thin mucus. Take 1 tablet every 4 hours with water.

✅ EASY TO SWALLOW: Our 400 mg tablets are small in size making it easier to swallow to promote clearer breathing by providing continuous relief through out the day and night. Enjoy cough mucus relief with tablets that can be used by those with allergies, colds, infections, and flu bugs.

Compare to VicksDayquil Cold & Flu LiquiCaps / Each softgel contains Acetaminophen 325mg,Dextromethorphan HBr 10mg, Phenylephrine HCl 5mg.

Relieves common cold and flu symptoms / nasal congestion / sore throat / headache / fever reducer / Pain reliver / cough due to minor throat and bronchial irriation.

Our small and compact packages are light weight and can easily fit in your purse, luggage, glove compartment, etc! The perfect mobile solution to keep you healthy and enhance your travel experience!

MAXIMUM STRENGTH RELIEF: Maximum Strength Mucinex Fast-Max Severe Congestion & Cough helps relieve cough, thins and loosens mucus and relieves chest and nasal congestion

#1 TRUSTED COLD & COUGH BRAND: #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand

COUGH SUPPRESSANT: Contains Dextromethorphan HBr that helps relieve cough

MAXIMUM STRENGTH RELIEF: Maximum Strength Mucinex Fast-Max Cold, Flu & Sore Throat helps reduce fever, relieve cough, sore throat, stuffy nose, chest & nasal congestion, headache and minor aches and pains

#1 TRUSTED COUGH & COLD: #1 Cough & Cold Brand Doctors Trust* and #1 Pharmacist Recommended Brand

PAIN RELIEVER: Contains Acetaminophen which reduces fever and relieves minor aches and pains thereby relieving your sore throat pain

MULTI-SYMPTOM RELIEF: You’ll feel relief from headache, fever, sore throat, nasal congestion, cough, mucus, and chest congestion with Rite Aid. Compare Rite Aid Pharmacy’s Severe Cold & Flu caplets to the active ingredients in top national brands.

FOR YOUR SEVERE SYMPTOMS: With Rite Aid Severe Cold & Flu sinus medicine for adults, you’ll get a pain reliever/fever reducer, cough suppressant to calm your cough, expectorant to power through mucus, and nasal decongestants for adults for congestion.

FEVER & PAIN RELIEVER: 325mg of Acetaminophen in each caplet temporarily relieves common cold symptoms like minor aches and pains, headache, sore throat and fever. While our cough suppressant and nasal decongestant clear your cough and congestion.

MULTI-SYMPTOM RELIEF: Mucinex Junior Cough & Congestion helps control cough, thins and loosens mucus, relieves chest congestion and stuffy nose

#1 PEDIATRICIAN RECOMMENDED: Mucinex Children’s is the #1 Pediatrician Recommended Brand among Non-Homeopathic Children’s Cough / Cold OTC products

COUGH SUPPRESSANT: Contains Dextromethorphan HBr which helps control cough

MAXIMUM STRENGTH MUCINEX FAST-MAX: Multi-Symptom Relief medicine; get back to what’s important thanks to the fast, powerful medicine

DAY TIME MULTI-SYMPTOM RELIEF: Maximum Strength Day time Severe Congestion & Cough Caplets helps relieve sinus pressure, nasal and chest congestion and cough

NIGHT TIME MULTI-SYMPTOM RELIEF: Maximum Strength Night time Cold & Flu Caplets helps reduce fever, relieve cough, nasal congestion that leads to stuffy nose, minor aches and pains, headache, sneezing, runny nose and sore and itchy throat

Temporarily relives these symptoms associated with the common cold or flu: headache; fever; minor body aches and pains; nasal congestion; runny nose; sinus pressure; sneezing.

Improve Your Long-Term Health -- Nebulizer machine can be used as a preventive medicine to protect your health.

Help You Remain Active -- The fear of having a respiratory attack can make you avoid social situations that you would otherwise love to attend. Having a nebulizer with you at all times can get you out of the house and back into life.

Portable -- It comes in sizes small enough to take with you across town, out of state, or overseas. It's easy to set up.

Kirkland Signature Cold Multi-Symptom combo pack includes both daytime and nighttime gel caps. Get relief from cold or flu, both day and night, in this one package.

Daytime Non-Drowsy Cold Multi-Symptom formula offers temporary relief from fever, headache, sore throat, nasal congestion and coughing associated with a cold or flu.

2 bottles of 60 count Daytime/48 count of Nighttime

✅ COUGH & COLD RELIEF: Whether for a dry or wet cough, Right Remedies softgels can provide up to 8-hours of continuous relief with fast acting results

✅ COUGH SUPPRESSANT: Right Remedies cough relief softgels temporarily relieves cough due to minor throat and bronchial irritation as may occur with the common cold.

✅ EASY TO SWALLOW: These softgels are easier to take than ill-tasting liquids or dry pills that leave aftertaste. This product reaches digestive system and starts working faster and efficiently.

20 count of Theraflu Max Strength (1) Flu Symptom Relief Caplets plus 20 count of Theraflu Max Strength (1) Nighttime Flu Medicine for Flu Symptom Relief Caplets

Theraflu flu symptom relief for daytime provides powerful relief from flu symptoms such as sore throat pain, headache, body aches and pains, cough and fever

Nighttime provides powerful relief from flu symptoms such as sore throat pain, headache, body aches and pains, cough and also provides relief from runny nose

Quality Choice Max Strength Mucus Relief Cold, Flu & Sore Throat, Compares to the Active Ingredients in Mucinex Fast-Max Cold, Flu & Sore Throat. Comes in a 20 count package.

Max Strength Cold Flu & Sore Throat is a Pain Reliever, Fever Reducer, Cough Suppressant, Expectorant and Nasal Decongestant designed to provide relief and restore comfort.

Maximum Strength Cold and Flu Medicine containing 325 mg of Acetaminophen for pain and fever relief, 10 mg of Dextromethorphan HBr a cough suppressant, Guaifenesin 200 mg an expectorant, and Phenylephrine HCI 5 mg a Nasal Decongestant.

Pack of 2, 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold

This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.

Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs

Powerful, Fast-Acting Relief: Cabinet provides severe cold medicine relief for multiple symptoms including fever, cough, congestion, sore throat, and minor aches and pains.

Comparable to the Leading Cold & Flu Medicine: Contains active ingredient Cetirizine (comparable to Dayquil Severe Cold & Flu. Cabinet works fast to help you power through the day - no matter what your symptoms are!

Multi Symptom Relief from the Most Severe Symptoms: Use this Daytime Severe Cold & Flu from Cabinet Health to mend your worst cold symptoms without buying another plastic bottle. This cold and flu medicine provides maximum-strength, non-drowsy relief from common cold and flu symptoms like fever, cough, congestion, sore throat, and minor aches and pains.