Best Tylenol Flu Medicine in 2026

Daisy
Last Updated: Feb 12, 2026

At a Glance: Our Top Picks for Tylenol Flu Medicine

Amazon Basic Care Daytime Cold & Flu Liquid, Orange Flavor, 8 Fluid Ounces
#TOP1
Amazon Basic Care Daytime Cold & Flu Liquid,
9.9
PM SCORE
Vicks VapoInhaler, On-the-Go Portable Nasal Inhaler, Non-Medicated, With Refreshing Vicks Vapors, Menthol Scent , 2 Scented Sticks
#TOP2
Vicks Vapoinhaler, On-The-Go Portable Nasal Inhaler, Non-Medicated, With
9.9
PM SCORE
Vicks NyQuil Cold and Flu Relief Liquid Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Sneezing, Runny Nose, and Cough, 48 Liquicaps
#TOP3
Vicks Nyquil Cold And Flu Relief Liquid Medicine,
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Tylenol Flu Medicine of 2026

Market Overview
Tylenol Flu Medicine Reviewed
  • Reviews Analyzed: 156312 Items
  • PM Avg. Rating: 8.4 / 10
71 Products Evaluated
  • Highest Price: $49.64
  • Lowest Price: $6.03
  • Avg. Price: $15.87

Amazon Basic Care Daytime Cold & Flu Liquid, Orange Flavor, 8 Fluid Ounces

AMAZON BASIC CARE
0615190
2.18 X 2.25 X 6.48 Inches
0.67 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ACTIVE INGREDIENTS: This cold and flu medicine contains acetaminophen (pain reliever/fever reducer), dextromethorphan HBr (cough suppressant) and phenylephrine HCl (nasal decongestant) which compare to the active ingredients in Vicks DayQuil Cold and Flu

MULTI-SYMPTOM RELIEF: Temporarily relieves headache, fever, sore throat, minor aches and pains, nasal congestion and cough due to the common cold and flu

NON-DROWSY: Each dose is designed for daytime use, so you can get through the day

MAXIMUM STRENGTH: When a cold or flu strikes, you need powerful relief

FOR AGES 6 AND OVER: For adults and children ages 6 and older; take as directed for cold and flu medicine that is alcohol, antihistamine and gluten free

Vicks Vapoinhaler, On-The-Go Portable Nasal Inhaler, Non-Medicated, With Refreshing Vicks Vapors, Menthol Scent , 2 Scented Sticks

VICKS
283691
3.39 X 0.79 X 4.29 Inches
0.01 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

SOOTHING NON-MEDICATED VICKS VAPORS: Experience Vicks vapors in a portable, easy nasal inhaler

ON-THE-GO CONVENIENCE. Vicks VapoInhaler is pocket-sized, discrete and can be used almost anywhere.

COMFORTING VICKS SCENT YOU CAN TRUST. Contains Vick’s proprietary blend of fragrance ingredients including menthol & camphor.

EASY TO USE. Just inhale refreshing non-medicated vapors through each nostril & use as often as needed.

FOR DAYTIME OR NIGHTTIME USE. Perfect addition to your daily routine to help you feel refreshed whenever you need it, day or night.

Vicks Nyquil Cold And Flu Relief Liquid Medicine, Powerful Multi-Symptom Nighttime Relief For Headache, Fever, Sore Throat, Minor Aches And Pains, Sneezing, Runny Nose, And Cough, 48 Liquicaps

VICKS
2.00 X 3.32 X 4.32 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

FAST, POWERFUL MULTI-SYMPTOM RELIEF for your headache, fever, sore throat, minor aches and pains, sneezing, runny nose, and cough

EFFECTIVE NIGHTTIME COLD & FLU SYMPTOM RELIEF. NyQuil Cold & Flu Liquicaps temporarily relieves common cold & flu symptoms so you can get the rest you need

FAST RELIEF SO YOU CAN SLEEP. Don't let your cold keep you up. Just one dose of NyQuil starts working fast to provide effective cold & flu relief

POWER THROUGH YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil relieves bothersome symptoms such as cough and fever so that you can get the rest you need

WORLD'S #1 SELLING OTC COUGH AND COLD BRAND**. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms

Vicks Dayquil And Nyquil Combo Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime And Nighttime Relief For Headache, Fever, Sore Throat, Cough, 24 Count, 16 Dayquil, 8 Nyquil Liquicaps

VICKS
418641
4.25 X 2.00 X 3.31 Inches
0.15 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Larkin Supply 9.88

Features

FAST, POWERFUL MULTI-SYMPTOM RELIEF: Use non-drowsy DayQuil for daytime relief and at night try NyQuil for fast relief so you can rest

EFFECTIVE COLD & FLU SYMPTOM RELIEF: DayQuil and NyQuil Cold & Flu medicine temporarily relieve common cold & flu symptoms

FEEL BETTER FAST: Just one dose starts working fast to provide effective cold & flu relief

POWER THROUGH YOUR WORST COLD & FLU SYMPTOMS: Life doesn’t stop when you have a cold, DayQuil and NyQuil relieve bothersome symptoms, such as cough and fever, day and night

WORLD'S #1 SELLING OTC COUGH AND COLD BRAND** Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms

#TOP5

Vicks Calming Lavender Vapopad Family Pack, 12 Count

VICKS
VSP30FP
3.00 X 1.20 X 5.60 Inches
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
American Direct Wholesale 9.85

Features

Calming lavender vapor: Vicks calming menthol & lavender VapoPads are designed to work with your Vicks humidifier or vaporizer to gradually release soothing aromatic vapors each pad contains 8 hours of scent

Added comfort: Non-medicated Vicks calming VapoPads are uniquely designed to work with your Vicks humidifier to release soothing vapors to enhance your humidification experience and to help provide added comfort

Cough & congestion relief: When you or your child has a cold, it can be difficult to sleep through the night Humidifiers provide temporary relief so your rest won't be as disturbed by coughing fits

Vicks vaporizers, humidifiers, & steam Inhalers: Steam & humidity offer relief from cough & congestion due to colds or allergies, helping you breathe easier wherever you are, from bedroom to office

Humidifiers for bedrooms, desks, tables: Our humidifiers & vaporizers help you breathe better wherever you are.

Vicks Soothing Vapors Replacement Pads, White, 6 Count

VICKS
VVP-6
3.00 X 0.88 X 5.13 Inches
0.04 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

VAPOPADS REFILL – These Vicks VapoPads are non-medicated refill pads for Vicks Plug-Ins, Vaporizers, Waterless Vaporizers and Humidifiers. This 6 count pack of vapor pads is designed to provide relief from cold, cough and flu with soothing menthol vapors

LONG-LASTING RELIEF – Each pad provides eight hours of comfort with Vicks plug-in and waterless vaporizers, inhalers and humidifiers, so you can breathe easier and sleep better

NO MESS REFILL – These menthol vapor pads are easy to use and install, with no messy spills. You’ll never have to worry about plug-in liquid spills again

A CENTURY OF POWERFUL RELIEF– At Vicks, we believe that everyone deserves a touch of care Our line of humidifiers, steam inhalers and vaporizers help you breathe better and sleep more comfortably, wherever you are

FOR USE WITH: V1200, V1300, VIH200, V150, V1700, V1750, V1800, V1900, VEV320, V3700, V3900, V4600, V5100, VUL520, VUL570, VUL575, V750, VWM845

Vicks Nyquil Cold And Flu Nighttime Relief Liquid Capsules, 16 Count

VICKS
604959
1.06 X 1.06 X 3.25 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Temporarily relieves common cold and flu symptoms including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing.

Vicks Inhaler Relief For Cold Sinus Nasal Congestion Allergy 3Pack

VICKS
900268
1.97 X 1.97 X 1.97 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Blessings Decor 9.87

Features

Vicks Vapor Inhaler Blister Card (3-Pack)

#TOP9

Vicks Pediatric Vapopads Refill Pads 6 Ea (Pack Of 4)

VICKS
PPAX1260130
4.00 X 4.00 X 6.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
American Direct Wholesale 9.85

Features

VICKS VAPOPADS SOOTHING SLEEPY TIME COMFORT: Vicks VapoPads can be used with many of our humidifiers and vaporizers, for added comfort and relief. The rosemary, lavender and eucalyptus scent of these vapor pad refills helps you to relax and fall asleep

VICKS VAPOPADS & VAPOSTEAM: Using medicated or non-medicated VapoPads or VapoSteam in your Vicks vaporizer or humidifier can help you feel more comfortable. Try Vicks' camphor cough suppressant VapoSteam, soothing menthol or rosemary & lavender VapoPads

COUGH AND CONGESTION RELIEF: When you have a cold, coughing and congestion can make you miserable. Vicks personal steam inhaler provides temporary relief from coughing and congestion, so you get a rest from coughing fits and can breath more freely

VICKS VAPORIZERS, HUMIDIFIERS, & STEAM INHALERS: Steam & humidity offer temporary relief from cough & congestion due to colds or allergies. Vicks line of humidifiers & steam inhalers, help you breathe easier wherever you are, from the bedroom to office.

HUMIDIFIERS FOR BEDROOMS, DESKS,TABLES: Our humidifiers & vaporizers help you breathe better wherever you are.

Vick Nyquil Cough Cold And Flu Nighttime Relief, Original Liquid, 2X12 Fl Oz

VICKS
323900014299
2.75 X 5.25 X 6.85 Inches
1.82 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Enterprise Driven 7.68

Features

Temporarily relieves common cold and flu symptoms including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing

NyQuil Liquid is available in three flavors: Original, cherry and vanilla cherry swirl

When using DayQuil or NyQuil products, carefully read each label to ensure correct dosing

Use as directed. Keep out of reach of children

Keep out of reach of children

Healtha2Z Daytime Cold & Flu Relief - Non Drowsy | 20 Count Softgels | Compare To Vicks® Dayquil® Cold & Flu Liqui Caps Active Ingredient

HEALTHA2Z
FP0692
4.33 X 1.16 X 3.50 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
HealthA2Z 9.95

Features

Compare to VicksDayquil Cold & Flu LiquiCaps / Each softgel contains Acetaminophen 325mg,Dextromethorphan HBr 10mg, Phenylephrine HCl 5mg.

Relieves common cold and flu symptoms / nasal congestion / sore throat / headache / fever reducer / Pain reliver / cough due to minor throat and bronchial irriation.

Our small and compact packages are light weight and can easily fit in your purse, luggage, glove compartment, etc! The perfect mobile solution to keep you healthy and enhance your travel experience!

Crane Menthol-Eucalyptus Universal Vapor Pads, 12 Pack, For Use Droplets, Corded Inhaler, Warm Mist Humidifier

CRANE
5.50 X 3.00 X 1.00 Inches
2.00 ounces
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

COMPATABILTY: Universal vapor pads designed for use with Crane Droplets (EE-5302), Corded Steam Inhaler (EE-5955), and Warm Mist Humidifiers (EE-5202). These vapor pads are also compatible with all Vicks’ humidifiers, vaporizers, and steam inhalers

NATURAL AND EFFECTIVE THERAPY: Feel relieved about using Crane’s natural and non-medicated vapor pads instead of over the counter medicines for symptomatic relief from cold, flu, and allergies

MENTHOL VAPOR: Crane’s menthol vapor pads are made with ingredients including menthol, peppermint, eucalyptus, & spearmint that help decongest and relieve coughing. Also, try our lavender calm and sleep vapor pads (HS-1950L)

EXTENDED USE: Crane’s soothing vapor pads last up to 4 treatment sessions or 8 hours ensuring the relief from cough & cold symptoms provided by the vapor pad will last through the night so you can wake up feeling like yourself again

ELEVATED EXPERIENCE: With the addition of these menthol vapor pads your humidification experience will instantly be enhanced whether it is used with Crane or Vicks cool mist humidifiers, warm mist humidifiers, or corded steam inhalers

Vicks Kids Nyquil/Dayquil Honey Cold & Cough + Congestion Relief Combo Pack For Nighttime & Daytime Cough & Congestion, Flavored With Real Honey, For Children Ages 6+, 8 Fl Oz Nyquil, 8 Fl Oz Dayquil

VICKS
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

DAY AND NIGHT COLD AND COUGH RELIEF FOR KIDS: Relieves your child's cough, cold, and congestion symptoms

FLAVORED WITH REAL HONEY. Great-tasting honey flavor your child will love

FAST, PROVEN RELIEF. Don’t let cold and cough symptoms interfere with your child's life. NyQuil and DayQuil Kids Honey will help them get the rest they need and then get on with their day

DESIGNED FOR CHILDREN. Formulated free of alcohol, aspirin, acetaminophen, and high fructose corn syrup

FORMULATED FOR CHILDREN AGES 6 AND OLDER

Goodsense Nighttime Cold & Flu Relief, Pain Reliever, Fever Reducer, Cough Suppressant & Antihistamine, 8 Fluid Ounces Green

GOODSENSE
33534
2.18 X 2.25 X 6.48 Inches
0.67 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Vitabox 9.88

Features

ACTIVE INGREDIENTS: This product contains acetaminophen (pain reliever and fever reducer), dextromethorphan HBr (cough suppressant) and doxylamine succinate (antihistamine) which compares to the active ingredients in Vicks NyQuil Cold & Flu

POWERFUL NIGHTTIME RELIEF: This cold and flu medicine provides multi-symptom relief of common cold and flu symptoms while you sleep

PAIN RELIEVER AND FEVER REDUCER: Relieves sore throat, minor aches and pains and reduces fever associated with the common cold and flu

COUGH SUPPRESSANT: This nighttime cold and flu relief medicine helps to relieve coughing so you can rest

ANTIHISTAMINE: Helps relieve runny nose and sneezing associated with the common cold and flu

Vicks Advanced Soothing Vapors Waterless Vaporizer With Night Light And Vapopads To Help Relieve Discomfort From Colds And Flu , 1 Count (Pack Of 1)

VICKS
V1750
2.40 X 2.30 X 5.30 Inches
0.10 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

VICKS VAPORIZER & VAPOPADS: Plug the Vicks Waterless Vaporizer into an outlet & enjoy soothing Vicks vapor with a non-medicated menthol scent. This plug in waterless vaporizer provides a soft glow nightlight for nights when feeling unwell keeps you up.

VICKS VAPORIZERS FOR KIDS, ADULTS: This waterless vaporizer helps add a soothing scented vapor into the air. Many women & men find that a vaporizer or humidifier for the bedroom becomes part of a good night's sleep in allergy season, or when sick.

SOOTHING VAPOR: When you or your kid has a cold, it can be difficult to sleep through the night. This waterless vaporizer releases soothing, non-medicated vapors, making bed time seem more comfortable and inviting as you snuggle in for a restful night.

VICKS VAPORIZERS, HUMIDIFIERS, & STEAM INHALERS: Steam & humidity offer temporary relief from cough & congestion due to colds or allergies. Other Vicks humidifiers & steam inhalers can help you breathe easier wherever you are, from the bedroom to office.

HUMIDIFIERS FOR BEDROOMS, DESKS, TABLES: Our humidifiers & vaporizers help you breathe better wherever you are.

Vicks Children's Multi-Symptom Cold Relief From Cough, Sore Throat, Fever; Free Of: Artificial Dyes & Flavors, High Fructose Corn Syrup & Alcohol, Citrus Orange Flavor, For Children Ages 6+, 6 Fl Oz

VICKS
B07QSBY91J
1.69 X 2.17 X 5.79 Inches
0.42 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Durr's Outlet 9.67

Features

MULTI-SYMPTOM COLD RELIEF FROM COUGH, SORE THROAT AND FEVER: Provides fast relief of aches, fever, sore throat, cough, and stuffy nose. Effective for up to 4 hours

SIMPLE, EFFECTIVE RELIEF: Specially formulated to be free of artificial dyes and flavors, high fructose corn syrup, and alcohol

DESIGNED FOR CHILDREN: Vicks Children's Multi-Symptom Cold Relief is designed to have a great-tasting, citrus flavor your child will love

PAIN RELIEVER, FEVER REDUCER, COUGH SUPPRESSANT AND DECONGESTANT: Contains Acetaminophen, Dextromethorphan HBr, and Phenylephrine HCI

FORMULATED FOR CHILDREN AGES 6+

#TOP17

Vicks Waterless Vaporizer V1800

VICKS
V1800
3.94 X 3.94 X 5.12 Inches
0.45 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
The Customer Land 9.69

Features

Comes with 5 scent pads

Up to 8 hours of soothing Vicks menthol vapors per pad

3 Settings for scent intensity control

Nightlight glows for nighttime visibility

Compact design and 6 foot cord for easy bedside use

Gurunanda Vapor Pads For Humidifier – Waterless Vaporize Pad For Congestion With Eucalyptus, Lavender, Cardamom & Mint Essential Oils - For Kids And Adults (6 Pack X 3 Reusable Pads)

GURUNANDA
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

UNIVERSAL COMPATABILTY - Universal vapor pads designed for use with Vicks Humidifiers, Vaporizers and Steam inhalers. Compatible with most other Brands using Vapor Pads/Scent Tray/Plug Ins.

BRAND THAT CARES FOR YOU - GuruNanda is built around good karma. By offering ethically sourced, top quality Ayurveda products at an affordable price point, GuruNanda ensures that every single purchase has an outsized positive impact for both customers and producers. A USA Brand!

SOOTHING & COMFORTING - GuruNanda Non-Medicated Vapor pads are made with Natural PURE Eucalyptus, Lavender, Cardamon, Bergamot mint Essential oil for extra comfort and relief. The soothing menthol vapours help you to relax, breathe easy and supports falling asleep. Could help providing temporary relief from Cough & Congestion, so you can rest without disturbance.

ENHANCED EXPERIENCE VS CONVENTIONAL VAPOR PADS – Unlike many Brands that mostly use artificial fragrances, GuruNanda Vapor pads include Pure Essential oils. These Vapor pads have PURE Eucalyptus, Lavender, Cardamon, Bergamot mint Essential oils that have Relaxing, Calming, Comforting and Protecting properties. This helps provide enhanced comfort, and congestion relief.

NO MESS USAGE - Easy to use and install, with no messy vaporizer liquid spills. Each Package comes with 3 packs of 6 vapor Pads each to provide long enough supply for your comfort.

Vicks Nyquil Nighttime Cherry, 8 Fl Oz (Old Version)

VICKS
01271393
2.30 X 2.20 X 6.35 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Essex Distribution 9.19

Features

Temporarily relieves common cold and flu symptoms including cough due to minor throat and bronchial irritation, sore throat, headache, minor aches and pains, fever, runny nose and sneezing

Nyquil liquid is available in three flavors original, cherry and vanilla cherry swirl

When using Dayquil or Nyquil products, carefully read each label to insure correct dosing use as directed keep out of reach of children

Quality Choice Nighttime Cold & Flu Cherry Liquid 12 Fl Oz

QUALITY CHOICE
QC90009
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
PLQC 9.84

Features

Compare to the active ingredients in Vicks Nyquil Cold & Flu

Acetaminophen

For the relief of Aches, Fevers, Cough, Runny Nose, Sneezing

For Ages 12 and over

12 Fl OZ

Vicks Jarabe Cough & Congestion Cold Medicine, Cherry - 8 Fl Oz

VICKS
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

POWERFUL COUGH AND CONGESTION RELIEF. Temporarily relieves cough due to minor throat and bronchial irritation, and thins and loosens mucus

COATING TECHNOLOGY. Coats and Soothes your throat by providing a refreshing sensation

Nyquil Liquid Cherry 8 Oz

VICKS
6.00 X 6.00 X 10.00 Inches
0.50 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
sweeteddy 9.19

Features

Vicks Cold & Flu, Nighttime Relief, 8 oz

Vicks NyQuil, Nighttime Cold & Flu Symptom Relief, Relives Aches, Fever, Sore Throat, Sneezing, Runny Nose, Cough, 8 Fl OZ, Cherry Flavor

Top 10 flu medicine Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Vicks 54
Amazon Basic Care 11
Healtha2Z 2
Crane 1
Goodsense 1
Gurunanda 1
Quality Choice 1

Top 10 flu medicine Brands Pie Chart


We've carried out a comprehensive analysis of 156,312 reviews on flu medicine, using our selection criteria to identify the best options in the health & household products. Our findings reveal that most customers typically select flu medicine priced around $15.87, with top brands including vicks, mucinex, valumeds, boiron, tylenol, amazon basic care, alka-seltzer plus, tukol and frida baby and sinus plumber

Our team of expert editors reviewed these high-quality items and handpicked the top 22 flu medicine for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the health & household products category. These include amazon.com, stam sales, valumeds, greensations products, genexa, babyluck and rite aid, inc. and divine sales direct .

We are dedicated to assisting our users in finding the right medicine Products based on their needs, saving them considerable time when choosing which flu medicine to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.