Best Powder Prebiotic Supplements in 2026

Targeted Strains for Vaginal & Urinary Boost*: With multiple targeted strains for women more closely mirroring the natural diversity of the human gut, our probiotics are carefully crafted to address the specific needs of woman's body. Taking regularly the specially targeted probiotics may help introduce helpful strains into your vagina & urinary tract, and reduce the binding of not-so-friendly micobes and yeast, thus maintaining yeast balance and vaginal & urinary tract health.*

Digestive Regularity & Immune Defense:* With a unique blend of 100 Billion CFUs from 32 carefully selected strains to encourage the flora diversity of your gut, this daily supplement helps restore digestive harmony and improve your intestinal health to fix issues with constipation or diarrhea.* Our shelf stable Women's Probiotics helps strengthen body’s natural defense by enriching and replenishing the useful microbes in the body.*

Professionally Formulated with Prebiotics Enzymes & Cranberries: Probiotics help restore the microbiota, while prebiotics provide the nutrients the microbes need to thrive on.* Organic Cranberry Extract, which naturally contains proanthocyanidins (PACs), can help prevent the adhesion of certain harmful microbes onto the walls of the bladder and help with UTI relief.* With enzymes built into this advanced formula, there’s no need to buy probiotics and digestive enzymes separately.

200 Billion CFUs Probiotics High Potency for Max Results: Not 50 or 60 Billion Cfus, our Summatah contains 200 Billion Cfus probiotic per serving daily. Powerful Strength Probiotic for Women and Men. Summatah probiotics provide you with a best probiotic supplement for your Digestive & Gut health, Gas & Bloating, and Immune support.

Digestive & Gut Health Support You Can Trust: Summatah 200 Billion CFU Probiotics can keep your digestive and gut health you need to meet life’s daily challenges, giving your body the right support. Our probiotic contains 12 diverse high-quality probiotic strains and 3 organic prebiotics - synergistically working together to support your digestive, gut Health gas & bloating,and Immune system!

Worth Every Penny: 60 capsules for 60-Day supply per bottle / 200 billion CFUs per serving daily. Powerful Strength Probiotic for Women and Men, it's a simple addition to your healthy routine. Shelf-stable, easily carry and swallow, take 1 capsule daily, to support you digestive & gut health, feeling you are at your best at this time, keeping your digestive, gut and body at PEAK condition.

Made for Healthy Digestion & Gut Immune Function: Formulated with 4.4 billion CFU spore-forming probiotics with built-in prebiotics, this dietary supplement helps support digestion, gut health and gut immune function*

Designed for Easy Digestion & Absorption: Contains an active blend of probiotics, including DE111, a clinically tested spore-forming strain that withstands stomach acid and is released in the intestine for better absorption.

Advanced, Dual Benefit Formula: Built-in PreforPro Prebiotics boost the effectiveness of probiotics, even in small doses. Together prebiotics and probiotics support the normal proliferation of beneficial gut flora and help to ease the digestive process.

Nature's Way Probiotic Pearls for Women is a daily probiotic for women to help support vaginal flora and urinary tract health with 1 billion live probiotic cultures.*

Pearls Women’s helps maintain vaginal and urinary tract health and supports digestive balance and immune health with active Lactobacilli cultures.* Triple-layer coating helps them survive their journey to your small intestine where they're needed most.

Women take 1 softgel daily. Small probiotic pearls are easy to swallow and conveniently sized to take anywhere and everywhere, with no refrigeration required.

WHY PROBIOTICS - Kids Nordic Flora Probiotic Gummies provide a synergistic blend of probiotics & prebiotic fiber to help establish and maintain healthy digestive balance with 1.5 billion CFU per serving.

COMPREHENSIVE CHILDREN’S HEALTH - When a child’s digestive tract is properly functioning, it can better absorb and utilize the nutrients needed for growth, development & strong immune function.

DELICIOUS & CONVENIENT - This go-anywhere gummy carries a research-supported amount of "good" gut bacteria perfect for smaller tummies. No refrigeration is required. This yummy merry berry punch flavor is for ages 2+.

300 Billion Cfus - More Active Probiotics for Max Strength: Not just 60 Billion or 150 Billion Cfus, our probiotic actually contains 300 Billion Cfus per serving daily. Our most popular probiotic brings you exactly what's on the label with 12 probiotic strains, 300 Billion Cfu, and 3 organic prebiotic blend. A complete probiotic supplement for ultimate digestive and gut health.

Happy Gut Flora, Happy Life - Our 300 Billion CFU probiotic are made for women and men. Our probiotic plus organic prebiotic naturally helps to balance to your gut, eliminating bloat and support the digestive system. Great for digestive and gut health, bloating, intestinal health and Support Immune Health.

Promote Healthy Digestion - Our probiotics are made with 12 probiotics and 2 prebiotics based on clinical research. 12 probiotics work with your body’s natural gut flora, helps Flush out Bad gut flora to support a healthy digestive tract and immune system. Prebiotics helps break down the food you eat, and nourishes your good gut flora so it can thrive and work more efficiently in your body.

Good health begins with your gut, so let the beneficial bacteria in our Ultimate 10+ Probiotics formula elevate your wellbeing. This advanced, quality-tested blend combines 10 digestive- and immune-boosting probiotic strains with two additional strains specifically selected to support respiratory health. So breathe easy...this supplement has got you covered.

To ensure these 30 billion colony forming units (CFUs) are potent and thriving the supplement contains prebiotic fiber to feed the healthy flora. Additionally, Ultimate 10+ Probiotics comes in a desiccant bottle designed to protect the formula by keeping out moisture.

The new and improved formula now supports: Digestive Health, Immune Health & Respiratory Health

Adult immune system booster - Adult probiotics can work wonders as an immune booster with pre and probiotics for women and men including the bifidobacterium probiotic to increase healthy gut flora

40 billion CFUs - Try our natural prebiotics and probiotics for digestive health with digestive probiotics to boost regularity and keep you on top of your game with a protective gut cleanse formula

Colon health - Help your bodily functions with our lactobacillus acidophilus probiotics for women and men with a natural colon cleanse complex with prebiotic and probiotic blend with 4 strains

IMMUNE SUPPORT: 50 billion CFU and 38 probiotic strains harvested directly from Bulgarian yogurt and Eastern European wild kefir, Yeast-Digesting Enzymes such as Cellulase and Fruits and Veggies, to support vaginal flora balance and urinary tract health

DIGESTION SUPPORT: This 50 billion CFU, once-daily probiotic supplement contains Lactobacillus acidophilus and Bifidobacterium (Bifidobacteria) lactis, and others for digestive health

PROBIOTIC FOR WOMEN: Maintaining a healthy bacterial balance in your digestive system is key to optimizing your overall well-being; Our Vaginal Care Blend includes 8 Clinically Studied Probiotic Strains for yeast balance, urinary tract and vaginal health

Delayed Release Delivery - Many probiotics do not reach the intestines, which makes them much less effective. Our delayed-release capsules increase intact delivery to the small intestine by protecting organisms from stomach acid.*

Advanced Probiotic/Bacteriophage Blend - Our PrePhage mixture is a proprietary blend comprised of four bacteriophages. They may be classified as prebiotics since they enhance the growth of beneficial flora in the gastrointestinal tract.*

7 Dairy-Free Probiotic Strains - Many probiotics contain dairy. Probiophage DF is a specialized bacteriophage formulation that includes seven strains of dairy-free probiotics.*

Clinically proven results- BioSchwartz advanced prebiotic contains a blend of PreforPro and PreticX prebiotic fibers that work better than inulin powder and other digestive enzymes to create your perfect microbiome. This allows for better absorption of nutrients and essential amino acids. Selective prebiotics support an increase of healthful bifidobacteria while inhibiting growth of undesirable microorganisms in the digestive tract.

Supports digestive health- Bloating, diarrhea and other intestinal issues affect many every day. BioSchwartz advanced prebiotics works in both intestinal areas of the body and is efficacious within hours. This supplement nourishes the flora of the intestinal lining to help promote regularity and ease occasional discomfort such as gas and bloating. When used with BioSchwartz probiotics, they can promote good bacteria growth that supports overall digestive health

Healthy microbiome leads to healthier lives - A healthy gut can support your natural immune response. It can also help with overall mood boost

⚕️PROPRIETARY COMBINATION OF STRAINS – This probiotic supplement contains 50 Billion CFU making it a highly potent health supplement. Additionally, our CONSTIPATION RELIEF probiotics are formulated with a unique proprietary blend of enzymes and other natural ingredients that aid in digestion while promoting your overall health and well-being.

💚DIGESTIVE ENZYME PROPERTIES – The blend of digestive enzymes in our ultimate flora probiotic helps your body properly digest food. Our vegan probiotics formula contains Milk Thistle and extract from the roots of Dandelion, Ginger, & Turmeric which have been shown to reduce inflammation in the body.

🌿 ESSENTIAL FOR GUT HEALTH – Taking our probiotics for women and men can restore the beneficial bacteria in your gut and work as a detox cleanse for your gut. This is necessary for improving the health of your liver, kidneys, and other organs. The prebiotics and probiotics replenish your intestinal ecology and can improve digestive health.

Clinically Researched Synbiotic Formula for MEN & WOMEN: Our easy-to-swallow 2-IN-1 Daily Care Probiotic features a unique blend of 19 different probiotic strains plus prebiotic fiber based on clinical researches. It delivers 60 billion CFU starter-friendly probiotics per serving to provide gentle nourishment to your gut lining, improve your digestion, and strengthen your immunity naturally.*

Survives Stomach Acid & Bile*: With advanced delayed-release technology, the beneficial bacteria in our formula can withstand stomach acid and bile, reaching deep into the intestinal tract alive for better absorption.* Besides, our 2-IN-1 Daily Care Probiotic is shelf-stable without refrigeration. Take two capsules a day, and feel Soothed, Relieved & Powered with Surebounty 2-IN-1 Daily Care Probiotic.

From Gut Lining to Digestive Comfort to Immunity*: Surebounty 2-IN-1 Daily Care Probiotic is specifically designed to restore the natural balance of good flora, maintaining the integrity of the intestinal lining, and protecting from leaky gut.* 100 mg of prebiotic is added to give daily support for your gut health, helping relieve occasional bloating & gas and promote bowel regularity.* 19 probiotic strains are carefully selected to enhance immune response and keep your guard up all day.*

BALANCED, EFFECTIVE FORMULA: Zentastic Probiotic is powered by 50 billion live cultures and features 16 beneficial strains, including Lactobacillus Acidophilus, to provide broad support for men's and women's overall health. Each veggie capsule also contains prebiotic fuel to empower these good organisms to flourish within the microbiome.*

DIGESTION SUPPORT & COGNITIVE HEALTH: Our probiotic strains are delivered deep into the intestinal tract to help replenish the good organisms in the gut. There, these beneficial strains support healthy digestion by promoting nutrient absorption and by providing relief for constipation, gas, and bloating. Healthy gut flora also plays a supporting role in healthy cognitive function and cardiovascular health.*

SUPPORT IMMUNE HEALTH, MOOD & ENERGY: Studies have shown that probiotics help strengthen the immune system and promote the growth of beneficial organisms in your gut. Probiotics can also support the nervous system and help maintain healthy mood and energy levels for a complete feeling of wellbeing.*

Kid Friendly Fiber Gummy - Children love our naturally sweet sugar free gummies packed with 4g of prebiotic chicory root fiber for kids making it easier than ever to support your little ones

Guilt Free Formula - We’re thrilled to present our high fiber sugar free gummy vitamins for kids made with naturally sweet inulin fiber that is halal kosher gluten free vegan and bursting with flavor

Benefit Rich Prebiotic Gummies - Stop struggling to get kids to take unsavory soluble fiber supplements and go for our digestive gummies that support digestive regularity and promote gut flora

PREBIOTICS AND PROBIOTICS SUPPLEMENT: Formulated with a prebiotic and 7 live probiotic strains, this supplement can help to replenish the natural balance of gut flora within the digestive system and help support immune system balance.

ACID- & BILE-RESISTANT PROBIOTIC CAPSULES: Our durable probiotic supplement contains 7 different probiotic strains of human origin, so it's easier to adapt to the human body. This men’s and women’s probiotic is also resistant to stomach acid and bile.

MADE WITH CARE: These capsules are mindfully sourced and contain the following natural probiotic strains: L. acidophilusL. casei (10%); L. plantarum (10%); L. rhamnosus (10%); B. lactis (10%); B. longum (5%); and S. thermophilus (5%).

✔️18 UNIQUE STRAINS WOMEN PROBIOTIC – Formulated with a proprietary blend of not one, but 18 unique probiotic strains, each serving of our probiotics for women digestive health delivers 50 billion CFUs of high quality lactobacillus and bifidobacterium strains.

✔️ CRANBERRY, VITAMIN C & PREBIOTIC FIBER – What makes our probiotic formula even better? We’ve also included cranberry, vitamin C and inulin prebiotic for the ultimate women’s probiotic supplement, and antioxidant support against free radicals.*

✔️ SMALL, EASY TO SWALLOW– Our easy-to-swallow BioXtend️ capsules are made to withstand harsh stomach acid, so that all strains are delivered and released in the gut where probiotics belong. As an added bonus, there’s no refrigeration required.

Probiotics + Prebiotic + Digestive Enzymes: 3-in-1 digestive health solution with clinicallyproven DE111 probiotic plus a spore-forming probiotic blend, a prebiotic, and a multi enzyme blend.

Clinically Proven DE111 Probiotic: Guaranteed to arrive alive and work within hours in small intestine where it inhibits candida growth and promotes overall women’s health.

Probiotics Alone Aren’t Enough: Probiotics PLUS digestive enzymes provide overall microbiome and digestive health and helps break down foods to reduce gas and discomfort.

PREGNANCY MUST HAVES: Does your prenatal supplement ritual start and end with a prenatal vitamin? Pink Stork Prenatal Probiotic is formulated JUST for pregnant women with vitamin B6, prebiotics, and seven strains of highly stable, spore-enhanced probiotics for pregnant women. Take one small capsule daily with your Pink Stork Prenatal Vitamins for women.

MORNING SICKNESS AND DIGESTION: Probiotics are good bacteria that help strengthen your gut barrier and cleanse bacteria from the body; this helps ease prenatal digestive issues, such as occasional morning sickness, constipation, bowel irregularity, or upset stomach.

PREBIOTICS AND PROBIOTICS: Our prenatal prebiotic and probiotic blend contains Inulin, Vitamin B6, and seven probiotic strains, including Bacillus Subtilis and Lactobacillus Paracasei for prenatal immune support, nutrient absorption, and gut flora balance - which also supports your developing baby's gut microbiome.

POWERFUL DIGESTION BUNDLE - Native Pet probiotic for dogs + pumpkin for dogs are the best combo for your dog's tummy! They combine to create the ultimate all-natural tummy dog diarrhea medication

VET NUTRITIONIST AND PHD DEVELOPED: our canine probiotic leverages an optimal blend of 4 probiotic strains, prebiotic fiber, & protein | our dog pumpkin powder is the perfect blend of dog fiber

PUMPKIN IS THE BEST SOURCE OF FIBER FOR DOGS: Native Pet Pumpkin for dogs is a the perfect blend of pumpkin, pumpkin seed & apple to form a powerful combo of soluble and insoluble fiber

16 Billion Probiotics, 6 Strains Chosen to Support Women's Health: Lactobacillus Crispatus, Lactobacillus Plantarum, and Lactobacillus Fermentum included to provide vaginal health support with ingredients that can aid in rebalancing your microbiome, support natural protection against harmful bacteria, and restoring vaginal flora.

Great for Sensitive Stomachs: Our selected strains are known to support a normal and healthy response to digestive issues like bloating, stomach pain, and poor nutrient absorption.

Plant-based Organic Prebiotics: Made from Organic Jerusalem Artichoke, prebiotics are the food that probiotics need to survive. We include prebiotic fiber specifically to help improve the efficiency of your probiotic. Jerusalem Artichoke is actually the root of a sunchoke that is high in fiber and a natural prebiotic - stimulating and feeding Bifidobacteria in the gut.

Fem-Dophilus contains two patented and clinically documented probiotic strains, Lactobacillus rhamnosus, GR-1 and Lactobacillus reuteri, RC-14, discovered and developed by Dr. Gregor Reid and Dr. Andrew Bruce at Urex Biotech

Over 25 years of research supports the oral use of GR-1 and RC-14 to colonize and promote healthy vaginal and urinary tract health

A special manufacturing process protects the probiotic strains in Fem-Dophilus from stomach acid and enhances probiotic bacterial survival to the lower intestine

HIGHER LEVEL OF CFUS AND STRAINS: Our 50 billion CFUs women probiotics contain a blend of 14 scientifically studied strains for digestive health, gut health, immune support and weight loss. Probiotic is protected by targeted release technologies and the 3-layer features stomach acid, bile protection. Allow strains to survive stomach acid and reach deep into the intestine to support a healthy gut. Our advanced strength formula can even reach your small intestine.

PRE AND PROBIOTICS FOR GUT AND DIGESTIVE HEALTH: 200 mg prebiotics feed and keep the probiotics alive, and produce more SCFAs to maintain the gut microbial balance. 14 strains support gut health and reduce digestive problems: diarrhea, constipation, bloating, abdominal pain, nausea and vomiting. Due to the interaction between the gut and the brain being, the gut is called the second brain, gut balance may boost your emotional well-being and cognition, suitable for menopause and women 55+.

Vaginal and Urinary Health: Probiotics for women is formulated with a higher ratio of Lactobacilli, L. reuteri and L. fermentum to support vaginal and urinary tract health. Contain 166 mg of D-mannose to help private health and ph balance to reduce the risk of urinary tract infection. D-mannose can adhere to harmful flora, such as E. coli which can cause urinary tract infection, stopping them from sticking to the wall of the urethra and being carried out of the body by urine.

HELPS YOUR DOG’S GUT FLORA TO WORK AS IT SHOULD: Probiotic and prebiotic chews with natural digestive enzymes give relief from frustrating health issues like gas, diarrhea, bad breath, upset stomach, constipation, bloating, hot spots, itchy skin, yeast infections and allergies.

BEST STRAINS = BIG GAINS: Contains 10 of the hardest working natural probiotics including Lactobacillus acidophilus, L. brevis, L. casei, L. fermentum, & B. bifidum. Carefully crafted by Pharmacist and Veterinarian experts to restore gut and bowel health. Promotes rapid improvements in digestion, intestinal well-being and helps maintain gut flora in the digestive tract.

BOOSTS ENERGY, HEALTH & HAPPINESS: Invigorates your furry friend by nourishing good bacteria in their gut, improving nutrient, vitamin and mineral absorption. Strengthens immune system helping to protect against germs and disease. Restores gut health following antibiotic use.

PreticX  Xylooligosaccharide (XOS) Prebiotic

Clinically Validated to Nourish Intestinal Flora*

Advanced Prebiotic

3-In-1 Immediate Restore*: Terranics 3-in-1 formula of 36 targeted strains, food-based prebiotic fiber and natural enzymes offers INTENSIVE & INTEGRATED digestive support by proactively arming your gut with some extra help.* Multi-strain probiotics mirror & restore your gut diversity while prebiotics stimulate probiotic growth and further strengthen the performance of digestive system.* Full-spectrum enzymes help break down your food for easy digestion and maximum nutrient absorption.*

Regularity, Comfort & Healthy Digestion*: Specially designed for times of compromise to re-introduce friendly flora into your digestive tract and bring you back ease & comfort.* Our highest potency probitoics helps maintain beneficial flora, support gut lining integrity, aid the immune system, and relieve occasional episodes of digestive distress.*

Delayed Release & Shelf Stable: Each vegan capsule of Terranics immediate restore probiotics is scientifically made to give probiotics an added edge and the vitality needed to survive acid & bile so they can make it to your small intestine and colon. Our shelf-stable bottle helps ensure 200 billion live cultures until date of expiration. No refrigeration required.

The First Precision Prebiotic Supplement - Designed to selectively feed beneficial flora, this gut health support supplement is made up of clinically tested, non-digestible oligosaccharides that can increase microbial diversity. Designed to complement daily fiber intake and support gut health.*

Why Choose a 'Precision Prebiotic'? Standard bulky fiber supplements can also support ('feed') undesirable microorganisms in the GI tract. MegaPre unique gut health powder was designed to provide the intermediate byproducts (oligosaccharides) necessary to produce health-supportive flora, including Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria.*

Combine with MegaSporeBiotic - Prebiotics and probiotics work together. MegaPre prebiotic fiber REINFORCES the beneficial microbial changes created by MegaSporeBiotic to promote a strong and diverse microbiome, and may be an ideal addition to your prebiotics and probiotics supplement regimen. Delicious pineapple orange guava flavored powder designed for adults, teens and kids (ages 3+). Mix with 16oz of water or blend into your favorite smoothie.

NATURAL DIGESTIVE SUPPORT: Studies have shown that just one gram per day of NutraFlora may help to increase friendly flora by 500% in just four weeks! Each of Swanson's easy to swallow capsules delivers 750mg short-chain FOS for digestive wellness.

PROMOTES OVERALL GUT HEALTH: Prebiotic fiber helps to stimulate the growth of microflora in the digestive system, promoting optimal digestion and absorption for overall health and immune support.

DOSAGE INSTRUCTIONS: Our wellness supplements offer everyday solutions for an enhanced mind, body, and home using only the purest ingredients. For best results, take two veggie capsules one to two times per day, preferably with a probiotic.

RHAMNOSUS PROBIOTIC & INULIN - This Lactobacillus rhamnosus GG supplement, or Lactobacillus GG, is a probiotic strain formulated with inulin FOS prebiotic for greater effects, in gastro-resistant delayed released capsules.

DIGESTIVE SUPPORT, IMMUNE BOOSTER & FLORA HEALTH - Designed to support both healthy intestinal and vaginal flora, as well as to promote digestive comfort, and is recommended for restoring balance to gut flora.*

NON-GMO, GLUTEN FREE, VEGETARIAN FRIENDLY - Supersmart offers you an outstanding quality and choice of supplements for women and men, difficult to find elsewhere.

GET TO THE UTI BEFORE IT GETS TO YOU:AGH UTI is a probiotic made for women by women that helps support optimal urinary tract health, so you can finally get the relief you deserve. Take control over recurring UTI's in a simple, proactive way with a probiotic that is designed to prevent harmful bacteria from entering the urinary tract and reaching the bladder.

PURE, NATURAL PROTECTION: This formula naturally helps rebalance pH levels to encourage the growth of healthy gut bacteria for stronger protection of digestive and urinary tract health. By targeting UTI formation before it starts, you'll resolve the need for antibiotic treatment, which can cause further digestive upset.​

EXTRA-STRENGTH CRANBERRY EXTRACT SUPPORT: This 50B CFU probiotic is an extra-strength, preventative solution with a holistic design that helps target reoccurring UTI's from the source. Made with 275mg of CRANnaturelle (cranberry extract), our formula helps restore balanced pH levels, as well as healthy amounts of intestinal and vaginal flora, while flushing out urinary tract toxins, to help you manage the symptoms ​of UTI's and prevent them from coming back.