Best Refresh Rewetting Drops in 2026

Daisy
Last Updated: Jul 17, 2026

At a Glance: Our Top Picks for Refresh Rewetting Drops

Refresh Tears Lubricant Eye Drops (0.5 Fl Oz - 2 Count) & Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count - 60 Day Supply)
#TOP1
Refresh Tears Lubricant Eye Drops (0.5 Fl Oz
9.9
PM SCORE
Refresh Optive Mega-3 Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count
#TOP2
Refresh Optive Mega-3 Lubricant Eye Drops, Preservative-Free, 0.01
9.9
PM SCORE
Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary
#TOP3
Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Refresh Rewetting Drops of 2026

Refresh Tears Lubricant Eye Drops (0.5 Fl Oz - 2 Count) & Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count - 60 Day Supply)

REFRESH
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Contains Refresh Tears Lubricant Eye Drops, 0.5 Fl Oz (2 Count) and Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count) 60 Day Supply

Original strength formula; Relieves mild symptoms of eye dryness

FAST-ACTING EYE ITCH RELIEF: Relieves itchy eyes from allergies in as little as 3 minutes

Refresh Optive Mega-3 Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count

REFRESH
4.00 X 3.00 X 4.75 Inches
0.24 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Preservative-free moisture-rich formula; On-the-go single use vials

Designed to relieve eye dryness that may be due to Meibomian Gland Dysfunction.

Delivers advanced hydration and lubrication

Supports all three tear film layers

Helps prevent tears from evaporating

The only eye drop in the U.S. with Carboxymethylcellulose Sodium, Glycerin, and Flaxseed Oil (an inactive ingredient)

Hydrocell technology enables hydration and maintains the volume of cells on the ocular surface

The brand in preservative-free artificial tears; IRI Artificial tears preservative-free dollar and unit sales by manufacturer.

Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary

REFRESH
5783
5.00 X 5.00 X 5.00 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Original strength, preservative-free formula

Relieves mild symptoms of eye dryness

Instantly moisturizes and lubricates

Designed to act like your own natural tears

Great for sensitive eyes

Value size: 50 on-the go, single-use vials

Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.

The brand in preservative-free artificial tears; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Visine Red Eye Hydrating Comfort Redness Relief And Lubricant Eye Drops To Help Moisturize And Relieve Red Eyes Due To Minor Eye Irritations Fast, Tetrahydrozoline Hcl, 0.5 Fl. Oz

VISINE
MDB4901
1.07 X 1.76 X 3.75 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

0.5-fluid ounce bottle of Visine Red Eye Hydrating Comfort Redness Relief Eye Drops to offer eye redness relief in 30 seconds and lubricate irritated eyes

Formula contains 1% polyethylene glycol 400 and 0.05% tetrahydrozoline HCl which helps lubricate, refresh and relieve red irritated eyes

Fast-acting redness relief & moisturizing formula relieves symptoms due to minor eye irritations like exposure to smoke, lack of sleep and extended screen time and comes from Visine, a brand backed by 60 years of expertise

The sterile eye drops help hydrate to soothe eye irritation & provide redness relief

The small bottle is conveniently-sized and can be easily carried in your pocket, purse or bag for on-the-go relief anywhere

Refresh Contacts, Eye Drops, Contact Lens Comfort,Blue 0.4 Fl Oz Sterile

REFRESH
91822US
1.15 X 1.80 X 3.60 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Original strength formula

Relieves mild symptoms of eye dryness due to contact lens wear

Instantly moisturizes and lubricates

You may keep your contacts in upon application

May also be used to lubricate and rewet soft and rigid gas permeable (RGP) contact lenses and to cushion lenses prior to application

Silicone acrylate and fluorosilicone acrylate rigid gas permeable lenses are recommended for use with REFRESH CONTACTS. Consult your eye care practitioner to identify the lens you wear.

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Refresh Relieva For Contacts Lubricant Eye Drops, 0.27 Fl Oz Sterile

REFRESH
1.13 X 1.75 X 3.50 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Innovative formula specially designed for contact lens wearers

Relieves mild to moderate symptoms of eye dryness, irritation, and discomfort associated with contact lens wear

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

You may keep your contacts in upon application

May also be used to lubricate and rewet soft and rigid gas permeable (RGP) contact lenses and to cushion lenses prior to application

Silicone acrylate and fluorosilicone acrylate rigid gas permeable lenses are recommended for use with REFRESH RELIEVA FOR CONTACTS. Consult your eye care practitioner to identify the lens you wear.

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile

REFRESH
92056
3.60 X 1.90 X 1.00 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Original strength gel formula

Relieves dry, burning, irritated eyes

Alleviates discomfort

Keeps eyes feeling better longer

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun

Refresh Celluvisc Lubricant Eye Gel Drops, Single-Use Containers, 30 Count (Pack Of 1)

REFRESH
178053
4.06 X 3.00 X 2.01 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Original strength gel formula

Relieves dry, burning, irritated eyes

Alleviates discomfort

Keeps eyes feeling better longer

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Bausch & Lomb Dry Eyes Drops, Lubricant Relief, Preservative Free, Single Use Dispensers, Packaging May Vary, Transparent, 0.6 Ml, 30 Count

SOOTHE
622219
6.00 X 5.00 X 4.00 Inches
0.16 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

LONG LASTING, FAST RELIEF DRY EYE THERAPY: Use Soothe Lubricant Eye Drops to help moisturize & refresh dry eyes for long-lasting relief & comfort Formulated to relieve dryness of the eye & help prevent irritation

DRY EYE DROPS: Tear replacement drops are important to help relieve dry eye symptoms

BAUSCH + LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops

EYE CARE EXPERTS: For over 150 years, Bausch + Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more

EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to make sure your eyes feel healthy, moisturized, & protected

Refresh Digital Lubricant Eye Drops, 0.33 Fl Oz (Pack Of 1)

REFRESH
1.13 X 1.75 X 3.50 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Stam Sales 9.93

Features

Acts fast to relieve dryness, burning, irritation, and discomfort in the eyes that may be due to digital device use

Delivers soothing hydration by supporting all three tear film layers

Helps prevent tears from evaporating due to lipid layer deficiencies

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Refresh Tears Lubricant Eye Drops 0.5% 15 Ml (2 Pack) - Packaging May Vary

REFRESH
449725
0.11 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Refresh Plus dose more than just soothe and relieve your eyes.

Refresh Plus dose more than just soothe and relieve your eyes.

The packaging may vary

Clear Eyes Contact Lens Relief Soothing Eye Drops 0.50 Oz (0.5 Fl Oz (Pack Of 4))

CLEAR EYES
PPAX1160125
6.00 X 4.00 X 4.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Vitozon 9.75

Features

Sterile buffered solution refreshes and lubricates eyes

Can be used as needed while wearing contact lenses

Rewets contact lenses

Helps remove particles from lenses

Provides up to 12 hours of soothing comfort

Refresh Classic Lubricant Eye Drops, Preservative-Free,0.01 Fl Oz Single-Use Containers, 50 Count (Pack Of 1), Packaging May Vary

REFRESH
4889
6.00 X 4.00 X 4.00 Inches
0.20 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Relieves mild symptoms of eye dryness

Instantly moisturizes and lubricates

Designed to act like your own natural tears

Preservative-free formula

Great for sensitive eyes

Value size! 50 on-the go, single-use vials

The #1 selling brand in preservative-free artificial tears.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Top 10 rewetting drops Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Refresh 27
Clear Eyes 3
Visine 2
Soothe 1

Top 10 rewetting drops Brands Pie Chart


We've carried out a comprehensive analysis of 216,518 reviews on rewetting drops, using our selection criteria to identify the best options in the categories. Our findings reveal that most customers typically select rewetting drops priced around $15.69, with top brands including opti-free, refresh, boston, renu, bausch & lomb, clear eyes, biotrue, systane and amazon basic care and soothe

Our team of expert editors reviewed these high-quality items and handpicked the top 13 rewetting drops for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the categories category. These include amazon.com, jjbookit, buy wise from us, versure, mybatterysupplier, argamantic, healthy eyes, agepha and vitozon and direct sell group .

We are dedicated to assisting our users in finding the right drops Products based on their needs, saving them considerable time when choosing which rewetting drops to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.