Best Soothing Rewetting Drops in 2026

Daisy
Last Updated: Feb 7, 2026

At a Glance: Our Top Picks for Soothing Rewetting Drops

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each
#TOP1
Systane Ultra Lubricant Eye Drops, Artificial Tears For
10.0
PM SCORE
Refresh Tears Lubricant Eye Drops (0.5 Fl Oz - 2 Count) & Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count - 60 Day Supply)
#TOP2
Refresh Tears Lubricant Eye Drops (0.5 Fl Oz
9.9
PM SCORE
Allergy Eye Itch Relief Eye Drops by Alaway, Antihistamine, 10 mL
#TOP3
Allergy Eye Itch Relief Eye Drops By Alaway,
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Soothing Rewetting Drops of 2026

Market Overview
Soothing Rewetting Drops Reviewed
  • Reviews Analyzed: 150447 Items
  • PM Avg. Rating: 8.6 / 10
26 Products Evaluated
  • Highest Price: $42.95
  • Lowest Price: $4.49
  • Avg. Price: $15.18

Systane Ultra Lubricant Eye Drops, Artificial Tears For Dry Eye, Twin Pack, 10-Ml Each

SYSTANE
65143141
6.00 X 5.00 X 4.00 Inches
0.05 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

#1 Dr Recommended Brand of Artificial Tears*, packaging may vary

Extended Protection

Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature

Reduces both the signs and symptoms of dry eye

Quickly soothe irritated eyes wherever you are

Refresh Tears Lubricant Eye Drops (0.5 Fl Oz - 2 Count) & Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count - 60 Day Supply)

REFRESH
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Contains Refresh Tears Lubricant Eye Drops, 0.5 Fl Oz (2 Count) and Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count) 60 Day Supply

Original strength formula; Relieves mild symptoms of eye dryness

FAST-ACTING EYE ITCH RELIEF: Relieves itchy eyes from allergies in as little as 3 minutes

Allergy Eye Itch Relief Eye Drops By Alaway, Antihistamine, 10 Ml

ALAWAY
AB60109
4.00 X 4.00 X 6.00 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Eye drops for itch relief: Help relieve eye allergy symptoms caused by pollen, ragweed, grass, animal hair and dander in minutes with these antihistamine eye drops containing ketotifen.

Alaway antihistamine eye drops help provide eye itch relief in minutes and last for up to 12 hours. This prescription-strength formula works right at the source of eye allergy symptoms, so it relieves eye itch faster than most allergy pills.

Do you suffer from eye allergies? If you have eye allergy symptoms, then you know how uncomfortable itching, watering eyes caused by pollen, ragweed, grass, animal hair and dander can be.

Bausch and Lomb Alaway eye care: Since John Bausch opened an optical goods store in 1853, Bausch and Lomb has focused on innovation and quality in eye care products, from contact lenses to eye drops.

Refresh Optive Mega-3 Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count

REFRESH
95773
3.00 X 6.00 X 4.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Buy Wise From Us 9.95

Features

Preservative-free moisture-rich formula

Designed to relieve moderate symptoms of eye dryness.

Delivers advanced hydration and lubrication

Supports all three tear film layers

Helps prevent tears from evaporating

The only eye drop in the U.s. with Carboxymethylcellulose sodium, Glycerin, and Flaxseed Oil (an inactive ingredient)

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

On-the-go single use vials

The #1 selling brand in preservative-free artificial tears; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Boston Rewetting Drops For Rigid Gas Permeable Contact Lenses - 0.33 Ounce, 6 Pack

BOSTON
5509
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
VerSure 9.98

Features

* Soothes your eyes

Refresh Tears Lubricant Eye Drops 4X15 Ml, 1X5 Ml

REFRESH
REFRSH-MULT
3.15 X 3.15 X 1.18 Inches
0.22 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Trends Goods 9.89

Features

Protects and Lubricates the eyes

Reduces the risk of eye infection

Washes away foreign particles

Keeps The surface of the eyes smooth and clear

Systane Long Lasting Lubricant Eye Drops, 1 Fl. Oz (Pack Of 1)

SYSTANE
300650429306
4.00 X 4.00 X 6.00 Inches
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
EvergreenCreations 9.95

Features

Eyes feel moist and refreshed longer

Lasting relief; soothing comfort

Formulated to shield eyes from dry eye discomfort

Please read all label information on delivery

Refresh Optive Lubricant Eye Drops, Sterile, 0.5 Fl. Oz (Pack Of 1)

REFRESH
93241
3.55 X 1.80 X 1.20 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
JJBookIt 9.73

Features

Dual-action formula lubricates and hydrates

Relieves mild symptoms of eye dryness

Works fast by delivering soothing moisture

The doctor recommended brand with over 30 years of experience; Ipsos healthcare, 2019 REFRESH ECP Recommendation Study

Refresh Relieva Lubricant Eye Drops, 0.33 Fl Oz Sterile, Packaging May Vary

REFRESH
1.13 X 1.75 X 3.50 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Innovative formula relieves discomfort due to dry, irritated eyes

Prevents further irritation

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

Also available in a preservative-free formula and a formula for contact lens wearers. Store at 59-86F 15-30C

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Visine Allergy Relief Multi-Action Antihistamine Eye Drops, Red, Itchy Eyes, 0.5 Fl. Oz

VISINE
JO524937800
1.06 X 1.77 X 3.75 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

0.5-fluid ounce bottle of original prescription strength Visine Allergy Eye Relief Multi-Action Eye Drops with redness reliever & antihistamine for temporary relief of multiple eye allergy symptoms

These clinically-proven allergy eye drops contain 0.3% pheniramine maleate, an effective antihistamine to help relieve irritated red, itchy, eyes due to common allergens such as pollen, ragweed, grass, and animal hair and dander

The eye drops are also formulated with .025% of the redness reliever naphazoline hydrochloride to provide temporary relief from red eyes

Available in a convenient and compact size, these allergy relief eye drops fit easily in a purse, pocket, backpack or desk for effective symptom relief both at home and on-the-go

Visine is backed by 60 years of science and expertise. Experience effective multi-symptom eye allergy relief with Visine Allergy Eye Relief Multi-Action Eye Drops.

Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile

REFRESH
92056
3.60 X 1.90 X 1.00 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Original strength gel formula

Relieves dry, burning, irritated eyes

Alleviates discomfort

Keeps eyes feeling better longer

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun

Refresh Optive Advanced Eye Drops, 0.33 Fl Oz (Pack Of 2)(Twin Pack)

REFRESH
94771
1.26 X 2.20 X 3.81 Inches
0.04 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Triple-action relief drop

Lubricants and hydrates dry, burning, irritated eyes

Helps prevent tears from evaporating

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Systane Lubricant Eye Gel Drops, 10-Ml (Packaging May Vary)

SYSTANE
ALCON528448
1.25 X 1.76 X 3.86 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

#1 Dr Recommended Brand of Artificial Tears*

Thicker eye drop formulation that creates a protective shield over your eyes.

Convenience of a drop with a protection of a gel.

For the temporary relief of burning and irritation due to dryness of the eye

NOTE: PRODUCT PACKAGING MAY VARY

Systane Ultra Lubricant Eye Drops,0.14 Fl Oz (Pack Of 1)

SYSTANE
0065143131
1.28 X 1.78 X 3.31 Inches
0.04 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Dr Recommended Brand of Artificial Tears

Extended Protection

Fast Long-Lasting Dry Eye Symptom Relief

Reduces both the signs and symptoms of dry eye

Quickly soothe irritated eyes wherever you are

Refresh Digital Lubricant Eye Drops, 0.33 Fl Oz (Pack Of 1)

REFRESH
1.13 X 1.75 X 3.50 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Stam Sales 9.93

Features

Acts fast to relieve dryness, burning, irritation, and discomfort in the eyes that may be due to digital device use

Delivers soothing hydration by supporting all three tear film layers

Helps prevent tears from evaporating due to lipid layer deficiencies

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Clear Eyes Cooling Comfort Relief Eye Drops, 0.5 Fl Oz

CLEAR EYES
10678112101259A
6.00 X 4.00 X 4.00 Inches
0.01 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Clear Eyes Cooling Comfort Eye Drops provide cooling relief for red eyes

Relief from redness, dryness, burning, itching and irritated eyes

From the #1-selling eye drops brand

Provides up to 12 hours of soothing comfort

Contains 1 bottle of Clear Eyes Cooling Comfort Eye Drops, 0.5 fl oz

FSA- and HSA-eligible product in the U.S.

Bausch + Lomb Soothe Preservative-Free Lubricant Eye Drops, Xtra Protection, Box Of 30 Single Use Dispensers

SOOTHE
11-IPLQ-8OZF
2.95 X 2.17 X 4.72 Inches
0.15 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

EXTRA PROTECTION FOR DRY EYES: Soothe XP Preservative Free Eye Drops do what ordinary eye drops (non-lipid containing) can't This formula helps restore the eyes lipid layer for relief that lasts, but is preservative free for sensitive eyes

DIFFERENT THAN ARTIFICIAL TEARS: MGD, which often includes breakdown of the lipid layer, is the main cause of evaporative dry eye Soothe XP Dry Eye Drops help restore the lipid layer to seal in moisture & protect against further irritation

BAUSCH and LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops

EYE CARE EXPERTS: For over 150 years, Bausch and Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more

EYE DROPS & MORE: Bausch and Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to make sure your eyes feel healthy, moisturized, & protected

Clear Eyes Eye Drops, Contact Lens Multi-Action Relief,2 Count

CLEAR EYES
1.92 X 1.91 X 3.79 Inches
0.04 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Clear Eyes Contact lens multi-action relief eye drops. Use while wearing daily and extended-wear soft contact lenses

These soothing eye drops feature a sterile, buffered solution that refreshes and lubricates eyes for up to 12 hours

Moistens lenses and helps remove particulate matter that can cause irritation and discomfort

Pack of 2

Sensitive Eyes Contact Lens Solution By Bausch + Lomb, For Rewetting Soft Contact Lenses, 0.5 Fl Oz

BAUSCH & LOMB
620736
1.63 X 1.06 X 3.38 Inches
0.07 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

Soothes eyes while wearing soft contact lenses

Gentle, effective, solution for lens wearers with sensitive eyes

For rewetting soft contact lenses

Eye Ointment By Bausch & Lomb, Lubricant Relief For Dry Eyes, 3.5 G

SOOTHE
AB31336
0.01 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Vitabox 9.88

Features

Soothing nighttime dry eye relief

Contains no preservatives

Gentle enough to use as often as needed

Remove contact lenses before using

Amazon Basic Care Eye Drops Advanced, Lubricant/Redness Reliever, 0.5 Fl Oz

AMAZON BASIC CARE
1.00 X 1.88 X 3.19 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING

Features

ACTIVE INGREDIENTS: This product contains tetrahydrozoline HCl 0.05%, a redness reliever, as well as Dextran 70 0.1%, polyethylene glycol 400 1% and povidone 1%, which are lubricants. Compare to the active ingredients in Visine Advanced.

EYE REDNESS RELIEF: Temporarily relieves discomfort and redness of the eye due to minor eye irritations.

DRY EYE RELIEF: Amazon Basic Care Eye Drops Advanced helps to relieve dry, irritated eyes.

STERILE eye drops are specially formulated with a lubricant and redness reliever for effective relief of red, irritated eyes and to relieve dryness of the eye.

USE: To use, simply instill 1 or 2 drops in the affected eye(s) up to 4 times daily.

Visine Dry Eye Relief All Day Comfort Lubricant Eye Drops For Up To 10 Hours Of Comfort, Dry Eye Drops With Polyethylene Glycol, 0.5 Fl. Oz

VISINE
VSN49376
1.07 X 1.76 X 3.75 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

0.5-fluid ounce bottle of Visine Dry Eye Relief All Day Comfort Lubricant Dry Eye Drops to moisturize and soothe dry eyes and protect against further irritation

Sterile moisturizing eye drops start working in seconds to provide temporary relief of burning, eye irritation, and discomfort due to dryness of the eye

These eye drops start to relieve dry eye in seconds

From Visine, a brand backed by 60 years of expertise, these eye drops feature the lubricant polyethylene glycol 400 and provide up to 10 hours of comfort

Visine All Day Comfort Dry Eye Relief Eye Drops are available in a small, convenient-to-carry bottle for convenient relief anywhere, even on-the-go

Octiq Lubricant Eye Drops For Dry Eyes, Dry Eye Symptom Reliever (Twin Pack 2X 15 Ml Bottles)

OCTIQ
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Aytu Consumer Health 9.95

Features

OPTIC REFRESHMENT: Octiq drops moisturize and replenish the corneal surface, allowing the eyelids to glide smoothly over the eyes. It facilitates comfort for red eyes, itchy eyes, and sore eyes.

HIGH QUALITY: Octiq contains 0.3% hypromellose and cetrimide that act as tear substitutes for dry eyes. Hypromellose helps the eye remain lubricated and produces high quality artificial tears.

HYDRATION: Designed to hydrate and soothe dry eyes. These eye drops for red eyes are gentle, convenient and non-irritating.

LUBRICATING EYE DROPS: Oqtic help to provide soothing comfort and long-lasting eye lubricant, keeping your eyes feeling refreshed throughout the day. This exciting advanced formula helps maintain the natural moisture balance in your eyes, providing effective, long lasting dry eye relief for mild to moderate dry eye.

LUBRICATING EYE DROPS: Oqtic help to provide soothing comfort and long-lasting eye lubricant, keeping your eyes feeling refreshed throughout the day. This exciting advanced formula helps maintain the natural moisture balance in your eyes, providing effective, long lasting dry eye relief for mild to moderate dry eye.

Refresh Optive Gel Drops Lubricant Eye Gel, 0.33 Fl Oz (Pack Of 1) Sterile, Packaging May Vary

REFRESH
95459
1.13 X 1.75 X 3.50 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Extended relief plus protection for dry, irritated eyes

Our most comprehensive gel formula

Anytime relief, day or night

Feels like a drop but works like a gel for lasting comfort

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Refresh Digital Pf Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count (Pack Of 1)

REFRESH
2.00 X 3.00 X 4.00 inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Preservative-free formula acts fast to relieve dryness, burning, irritation, and discomfort in the eyes that may be due to digital device use

Delivers soothing hydration by supporting all three tear film layers

Helps prevent tears from evaporating due to lipid layer deficiencies

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

30 single-use vials

The #1 selling brand in preservative-free artificial tears.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Refresh Relieva Pf Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count

REFRESH
0330120
2.00 X 3.00 X 4.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Preservative free formula relieves discomfort due to dry, irritated eyes

Prevents further irritation

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

Recommended for sensitive eyes

Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.

On-the-go single use vials

Also available in a preservative-free formula that comes in a multidose bottle.

The #1 selling brand in preservative-free artificial tears.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Top 10 rewetting drops soothing Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Refresh 11
Systane 4
Clear Eyes 2
Soothe 2
Visine 2
Alaway 1
Amazon Basic Care 1
Bausch & Lomb 1
Boston 1
Octiq 1

Top 10 rewetting drops soothing Brands Pie Chart


We've carried out a comprehensive analysis of 150,447 reviews on rewetting drops soothing, using our selection criteria to identify the best options in the categories. Our findings reveal that most customers typically select rewetting drops soothing priced around $15.18, with top brands including refresh, biotrue, systane, clear eyes, opti-free, bausch & lomb, boston, amazon basic care and theratears and octiq

Our team of expert editors reviewed these high-quality items and handpicked the top 26 rewetting drops soothing for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the categories category. These include amazon.com, sportingdoc, versure, jjbookit, buy wise from us, evergreencreations, aytu consumer health, otcrx4u and mybatterysupplier and trends goods .

We are dedicated to assisting our users in finding the right drops Products based on their needs, saving them considerable time when choosing which rewetting drops soothing to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.