Best Bottle Sinus Medicine in 2025

Allergy Relief

Relief of sneezing, runny nose, itchy, watery eyes and more

Compare to active ingredients in Zyrtec

Temporarily relieves congestion due to common cold, hay fever, and other respiratory allergies

Decongestant nose drops help clear nasal passages and shrinks swollen membranes

Temporarily restores freer breathing through the nose and helps decongest sinus openings and passages

NATURAL SALINE SOLUTION & NASAL RINSE: Our nasal saline spray will gently clean and moisturize the sinus tissues. Unlike other normal saline nasal sprays our spray can also decongest the sinuses by targeting the primary causes of nasal congestion. Our nose spray will help reduce tissue swelling from pollen, pollution, contaminants, and other irritants.

SAFE NASAL RINSE & SPRAY: Our all-natural nasal cleaner is safe for kids, non-addictive, Non-GMO Project Verified and is effective without the use of steroids, drugs, or chemicals. It is the ideal daily sinus medicine that will reduce swelling and open your airways. Using our saline nose spray before bed may reduce snoring.

IMPROVED FORMULA WITH XYLITOL: Our patented saline nasal spray solution may reduce tissue inflammation and naturally open airways. Xylitol's powerful oral and upper respiratory health benefits come from its unique five-carbon structure. Xylitol may help reduce swelling and allergy symptoms by reducing contaminant adhesion on your nasal tissue.

1 SINUFLO READYRINSE Bottle 240 mL (8 fl oz) with Premixed Saline Solution

2 SINUS RINSE Refill Packets

Educational Brochure and Instructions of Use

4-fluid ounce bottle of Children's Tylenol Cold + Cough + Runny Nose Oral Suspension Medicine to temporarily relieve cold and flu symptoms, including, sore throat, cough, runny nose and sneezing

The kids' liquid pain relief medicine also relieves minor aches & pains, headache & temporarily reduces fever fast with an ibuprofen-, aspirin-, and alcohol-free formula

Each 5-milliliter dose of the children's medicine contains 160 milligrams of acetaminophen pain reliever and fever reducer; 1 milligram of the antihistamine chlorpheniramine maleate; and 5 milligrams of the cough suppressant dextromethorphan HBr

Bundle pack containing one 30-count bottle, one 14-count bottle and three 1-count travel packs of Zyrtec 24 Hour Allergy Tablets for powerful relief of your worst indoor & outdoor allergy symptoms

These prescription-strength cetirizine allergy pills work fast and stay strong by providing all-day allergy relief that starts working hard at hour one and works twice as hard when taken again the next day

Each powerful antihistamine tablet contains 10 mg of cetirizine hydrochloride and effectively treats indoor allergies caused by dust, mold, and pet dander, as well as outdoor seasonal allergies caused by tree pollen, weeds, and grasses

Package contains one 8.3 fl oz bottle of Theraflu Nighttime Severe Symptom Cold Relief Syrup, Berry Flavor and six packets of Theraflu Daytime Severe Cold Relief Powder, Honey Lemon Flavor

Multi-symptom cold medicine that provides powerful relief from severe cold and flu symptoms such as sore throat pain, headache, minor body aches and pains, sinus congestion, severe cough and fever

Theraflu cold relief packets dissolve quickly in hot water for daytime cough medicine and flu relief that is as easy as making a cup of tea, great for stocking up on for cold and flu season

12-count bottle of Children's Zyrtec 24 Hour Allergy Dissolve Tablets for all-day relief of allergy symptoms including runny nose, sneezing, itchy, watery eyes, and itchy nose & throat.

Each allergy tablet contains 10 milligrams of effective cetirizine hydrochloride antihistamine and melts in the mouth with a kid-friendly citrus flavor

Give your child effective relief from hay fever and other upper respiratory allergies with this prescription-strength allergy medicine for kids

Compare to Flonase Allergy Relief Active Ingredient

Fluticasone Propionate(Glucocorticoid) 50 mcg.

Indoor/Outdoor Allergy Relief

INCLUDES: One (1) 84-count bottle of Allegra Adult Non-Drowsy Antihistamine Tablets for 24-Hour Allergy Relief

24-HOUR RELIEF: One pill is all you need for round-the-clock relief from your worst allergy symptoms

FAST-ACTING: Allegra 24-Hour Allergy starts working in one hour for fast relief from sneezing, runny nose, itchy and watery eyes, and itchy nose or throat

#1 TRUSTED COLD & COUGH BRAND: Mucinex is the #1 Cold and Cough brand doctors trust* and #1 Pharmacist Recommended Brand

CONTAINS: 2 MINERAL CONCENTRATE REFILL = over 64oz of Allergen Spray. Bottle and sprayer not included!

REDUCE INDOOR ALLERGENS - Get relief from cat dander allergens, dog dander allergens and more with our Allergen Spray.

SAVE MONEY - Our 2 refill pack is an incredible value. Makes over 64oz of Allergen Spray. Use your own bottle & sprayer

✅ FULL 24 HOUR RELIEF - Enjoy non drowsy allergy relief that lasts for a full day. Cetirizine HCL helps alleviate symptoms of indoor and outdoor allergies like hay fever, pollen, dust, pet dander and seasonal allergies. Compare to the active ingredient found in Zyrtec over the counter medication.

✅ LESS ITCHING - Cetirizine HCL is a powerful antihistamine that helps relieve and prevent itchy watery eyes, runny nose, congestion and an irritated itchy throat. If you suffer from hives, cetirizine HCL 10mg may help reduce the itching and appearance of hives on your skin and face.

✅ NON DROWSY FORMULA - Unlike most allergy medications, Cetirizine HCL tablets are non drowsy and can be taken at any time of day. Each pill is small and easy to swallow for adults and children ages 6 and up. Protect you and your family with a convenient and easy to use OTC allergy medication.

One 72-spray bottle of Flonase Allergy Relief Nasal Spray, 24 Hour Non Drowsy Allergy Medicine, Metered Nasal Spray + Bonus Pack of TIssues

Containing the most prescribed allergy medication (1), Flonase relieves runny nose, sneezing, itchy nose and watery, itchy eyes, while also providing nasal congestion relief

Allergy nasal spray that provides 24 hour all-in-one relief for even your worst seasonal, year-round, indoor and outdoor allergy symptoms

One bottle of 20 coated tablets of Advil Multi Symptom Cold and Flu Medicine, Cold Medicine for Adults with Ibuprofen, Phenylephrine HCL and Chlorpheniramine Maleate

Powerful Ibuprofen 200mg, chlorpheniramine maleate 4mg and phenylephrine HCL 10 mg tablets for multi-symptom relief

Uniquely formulated to fight common cold and flu symptoms, providing nasal congestion, nasal swelling, sneezing, sinus pressure, headache, fever, body aches and runny nose relief

MULTI-SYMPTOM RELIEF: Sinus wash temporarily relieves symptoms associated with sinusitis, cold, flu, or allergies. Rite Aid rinse kit relieves sneezing, runny nose, nasal stuffiness, post nasal drip, and removes inhaled irritants such as dust & pollen.

ALL-NATURAL SALINE: Each packet includes 100% saline for use with your Neti Pot or squeeze bottle. Natural saline promotes nasal and sinus drainage, helps reduce swelling of nasal membranes, and allergy relief, all while moisturizing dry nasal passages.

INDIVIDUAL PACKETS: 100 nasal rinse salt packets included for convenient use. All-natural and safe option for both children and adults that’s doctor developed, medically proven, and works in all nasal wash systems— such as Neti Pots and squeeze bottles.

Afrin Original Nasal Spray & Decongestant, Fast/ Powerful Congestion Relief, 3 Bottles of 1 Fl Oz Each.

Works for up to 12 hours Provides nasal congestion relief due to colds or allergies Doesn’t cause drowsiness

Stimulates secretions to help clear mucus from the nose

Restores moisture to dry nasal membranes

Helps Clear congestion

Kirkland Signature Aller-Tec Cetirizine HCL 10 mg/Antihistamine Tablets365-tablets Bottle

EPIPEN CASE FOR KIDS: AllerMate’s Epinephrine Carrying Case for Kids is the ultimate first aid pouch and medicine case that can hold all emergency allergy supplies in one compact epipen case. This kid’s epinephrine holder comes with a thermometer strip that indicates temperature within 5 degrees, and small bottle for liquid meds. Bottle is BPA free with a child/ tamper proof cap.

QUALITY, COMPACT DESIGN FOR BUSY BOYS & GIRLS: Go hands free! This epipen carrying medicine case for kids can be worn with an adjustable belt to fit all ages. This blue insulated auvi-q bag is made of durable fabric meant to last for years to come! This blue medicine bag measures 8"H X 3"W X 1 3/4"D, ensuring that you have all the room necessary for the essentials, but small enough to take anywhere!

INSULATED INTERIOR: Keeps you and everything else looking cool! We recommend storing your ice gel packs inside this cold insulated bag to keep your meds within proper temperature when exposed to extreme heats. It would only be necessary to add an ice pack if you were carrying medicines around that were going to be exposed to heat for long periods of time (August, day at the beach , Arizona, etc..). It’s item pockets are specifically designed to prevent liquid spills.

NATURAL SALINE SOLUTION & NASAL RINSE: Our nasal saline spray will gently clean and moisturize the sinus tissues. Unlike other normal saline nasal sprays our spray also acts as a nasal decongestant by targeting the primary causes of nasal congestion. Our nose spray will help reduce tissue swelling from pollen, pollution, contaminants and all other irritants.

KID SAFE NASAL RINSE & SPRAY: Our all natural nasal cleaner is safe for kids, drug-free, non-addictive, Non GMO Project Verified and is effective without the use of steroids, drugs or chemicals. It’s the ideal daily sinus medicine that will reduce swelling and open your airways. Use our saline nose spray before bed to help reduce snoring.

IMPROVED FORMULA WITH XYLITOL: Our patented saline nasal spray solution reduces tissue inflammation and naturally opens airways. Xylitol's powerful oral and upper respiratory health benefits come from its unique five-carbon structure. Xylitol helps to reduce swelling and allergy symptoms by reducing contaminant adhesion on you nasal tissue.

ORIGINAL PRESCRIPTION STRENGTH: Quickly reduce the symptoms of indoor and outdoor allergies with Rite Aid Loratadine. Perfect for alleviating allergy symptoms any time of the day, these original prescription-strength tablets are specially designed with a non-drowsy formula. The long-lasting formula provides 24-hour allergy relief. Each bottle contains 120 tablets of powerful relief.

LORATADINE 10 MG: The active ingredient in each allergy pill is Loratadine 10 mg. Purpose: antihistamine. Inactive ingredients: lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate.

NON-DROWSY & FAST RELIEF: Get fast, non-drowsy relief from sneezing, runny nose, watery eyes, and itchy nose and throat. Adults and children 6 years and over: Take one tablet daily, and not more than one tablet in 24 hours. Children under 6 years of age: Ask a doctor. When using this product, do not take more than directed. Taking more non-drowsy allergy medicine than directed may cause drowsiness.

NATURAL SINUS RELIEF & NASAL RINSE: Xlear Rescue is a nasal spray with xylitol for when you need a stronger, but still natural, punch against whatever is causing your upper respiratory problems. Unlike other normal saline nasal sprays our rescue nasal saline spray acts as a nasal decongestant for severe sinus pressure and congestion by targeting the primary causes of nasal congestion. Our nose spray will help reduce tissue swelling from pollen, pollution and all other irritants.

IMPROVED HERBAL FORMULA WITH XYLITOL: Our patented saline nasal spray solution reduces tissue inflammation and naturally opens airways. With added herbal ingredients such as Pau d’Arco, and essential oils like oregano, parsley, eucalyptus, and tea tree, our nasal decongestant spray features properties that provides you relief when you need it most. Xylitol helps to reduce swelling and allergy symptoms by reducing irritant adhesion on you nasal tissue.

WASH AWAY POLLUTANTS: Our natural saline nasal spray can wash away pollutants and help to bring sinus relief. Use our sinus spray daily to protect and keep your nasal passages clean. Each 1.5 oz bottle delivers approx. 240 fine mist sprays so you can find fast and quick relief.

INCLUDES: One (1) 0.37 fl. oz. spray bottle of Nasacort Children's Allergy 24HR Nasal Spray

24-HOUR RELIEF: Nasacort Children's Nasal Spray provides a full 24 hours of relief from nasal allergy symptoms

MULTI-SYMPTOM RELIEF: Nasacort Spray relieves nasal allergy congestion, sneezing, and runny and itchy nose

Temporarily prevents and relieves nasal allergy symptoms including running/itchy nose, sneezing and allergic stuffy nose

Prevents and controls nasal allergy symptoms from occurring in the first place; 200 sprays per bottle

Non-habit forming; non-drowsy; no jitters; safe to use with other medications; full prescription strength without a prescription

MULTI-SYMPTOM RELIEF: Sinus wash temporarily relieves symptoms associated with sinusitis, cold, flu, or allergies. Rite Aid rinse kit relieves sneezing, runny nose, nasal stuffiness, postnasal drip, and removes inhaled irritants such as dust & pollen.

SOFT COMFORT TIP: Soft, flexible tip provides maximum comfort while using this nasal irrigation kit. Neti Pots use the gentle flow of gravity to wash nasal passages and has been clinically proven to provide effective relief for nasal congestion.

ALL-NATURAL SALINE: Included packets are all-natural saline for use with your Neti Pot or squeeze bottle. Natural saline promotes nasal and sinus drainage, helps reduce swelling of nasal membranes, and allergy relief, all while moisturizing dry nasal passages.

✅ ULTIMATE SINUS RELIEF - Experience maximum strength nasal decongestion and sinus pressure relief from indoor or outdoor allergies or common cold symptoms. 10 mg of Phenylephrine HCl helps alleviate pressure in your nose, sinus, ears, and throat.

✅ BREATHE EASIER - Lowering sinus pressure and eliminating congestion can help you breathe better and deeper during the day or night. This over the counter decongestant can help with common symptoms like runny nose or blocked nasal passages.

✅ NON DROWSY FORMULA - GenCare Nasal Decongestion can be taken any time of day including the morning or daytime. Many decongestant treatments are only suitable for nighttime use and are therefore limited for active adults and kids who need relief all day long.

NASAL SPRAY: To help relieve congestion by thinning mucus; To moisturize and irrigate membranes

FEATURES: Liquid formula for nasal dryness

MOISTURIZING: Help return moisture caused by drug-induced dryness while spending time in enclosed spaces such as during air travel

Mommy's Bliss saline Spray/Drops cleans, moisturizes and soothes delicate nasal passages for little ones (babies)

Easy Administration with dual-action bottle: for dropper use Hold bottle upside down and gently squeeze or for sprayer use Hold bottle upright and squeeze. Its easy! No refrigeration required

Gentle for newborns+: non-medicated, no preservatives, hypoallergenic and sterile

24-count bottle of Tylenol Cold Head Congestion Severe Caplets provide effective relief of multiple symptoms due to the flu and common cold

This severe cold & flu medicine helps relieve headache, minor aches and pains, sore throat, nasal congestion, and sinus congestion and pressure. It also temporarily reduces fever and helps to loosen phlegm to make coughs more productive.

Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches and pains, as well as 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion