Best Ointments Eye Drops in 2026

Daisy
Last Updated: Feb 7, 2026

At a Glance: Our Top Picks for Ointments Eye Drops

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each
#TOP1
Systane Ultra Lubricant Eye Drops, Artificial Tears For
10.0
PM SCORE
LUMIFY Redness Reliever Eye Drops 0.17 Fl Oz (5 mL)
#TOP2
Lumify Redness Reliever Eye Drops 0.17 Fl Oz
9.9
PM SCORE
Refresh Tears Lubricant Eye Drops (0.5 Fl Oz - 2 Count) & Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count - 60 Day Supply)
#TOP3
Refresh Tears Lubricant Eye Drops (0.5 Fl Oz
9.9
PM SCORE

* PickSmartly editors independently research, review, and endorse the top products through comprehensive data analysis. We may earn a commission for qualifying purchases made through our product links.

Summary of the Best Ointments Eye Drops of 2026

Market Overview
Ointments Eye Drops Reviewed
  • Reviews Analyzed: 253656 Items
  • PM Avg. Rating: 8.6 / 10
35 Products Evaluated
  • Highest Price: $50.84
  • Lowest Price: $4.98
  • Avg. Price: $16.82

Systane Ultra Lubricant Eye Drops, Artificial Tears For Dry Eye, Twin Pack, 10-Ml Each

SYSTANE
65143141
6.00 X 5.00 X 4.00 Inches
0.05 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

#1 Dr Recommended Brand of Artificial Tears*, packaging may vary

Extended Protection

Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature

Reduces both the signs and symptoms of dry eye

Quickly soothe irritated eyes wherever you are

Lumify Redness Reliever Eye Drops 0.17 Fl Oz (5 Ml)

LUMIFY
AB53705
1.69 X 1.06 X 3.44 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Eye Drops for Red Eyes: LUMIFY significantly reduces redness to help reveal your eyes' natural radiance. From the eye care experts at Bausch plus Lomb, LUMIFY works in 1 minute and lasts up to 8 hours

LUMIFY is different: The only OTC drop to contain brimonidine. It selectively targets redness, alleviating some potential side effects associated with other redness relief drops, when used as directed

Eye Care Experts at Bausch plus Lomb: For over 150 years, we have focused on innovation and quality in eye care products, from contact lenses and solutions to eye drops, ointments, eye vitamins, and more

Amazing Looking Eyes: We understand how important eyes are. And despite all the eye creams, mascara, eyeliners and eyeshadows, if your eyes are red, you won’t look your best

Refresh Tears Lubricant Eye Drops (0.5 Fl Oz - 2 Count) & Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count - 60 Day Supply)

REFRESH
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Contains Refresh Tears Lubricant Eye Drops, 0.5 Fl Oz (2 Count) and Lastacaft Once Daily Eye Allergy Itch Relief Drops, (1 Count) 60 Day Supply

Original strength formula; Relieves mild symptoms of eye dryness

FAST-ACTING EYE ITCH RELIEF: Relieves itchy eyes from allergies in as little as 3 minutes

Allergy Eye Drops By Bausch & Lomb, For Itch & Redness Relief, 15 Ml (Pack Of 2), Packaging May Vary

OPCON-A
AB55299
2.60 X 1.10 X 3.40 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

ALLERGY EYE DROPS: Opcon-A eye drops combine an antihistamine with redness reliever to help relieve itchy, red, irritated eyes. Temporarily relieves itching & redness caused by pollen, ragweed, grass, animal hair & dander

RELIEF FOR ITCHY EYES: Opcon-A eye drops are clinically proven to help temporarily relieve the redness & itching caused by symptoms of common airborne allergens like ragweed or grass

BAUSCH and LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops

EYE CARE EXPERTS: For over 150 years, Bausch and Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more

EYE DROPS & MORE: Bausch and Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to make sure your eyes feel healthy, moisturized & protected

Refresh Optive Mega-3 Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count

REFRESH
95773
3.00 X 6.00 X 4.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Buy Wise From Us 9.95

Features

Preservative-free moisture-rich formula

Designed to relieve moderate symptoms of eye dryness.

Delivers advanced hydration and lubrication

Supports all three tear film layers

Helps prevent tears from evaporating

The only eye drop in the U.s. with Carboxymethylcellulose sodium, Glycerin, and Flaxseed Oil (an inactive ingredient)

Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface

On-the-go single use vials

The #1 selling brand in preservative-free artificial tears; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Genteal Tears Lubricant Eye Drops, Moderate Liquid Drops, Twin Pack ,0.5 Fl Oz (Pack Of 2) Package May Vary

GENTEAL
0065042637
1.25 X 2.56 X 4.25 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Moderate Dry Eye Symptom Relief

Fast Soothing Relief

Quick relief from moderate irritation and discomfort

Relieves discomfort: Provides relief from moderate irritation and discomfort caused by dry eye symptoms

Systane Long Lasting Lubricant Eye Drops, 1 Fl. Oz (Pack Of 1)

SYSTANE
300650429306
4.00 X 4.00 X 6.00 Inches
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
EvergreenCreations 9.95

Features

Eyes feel moist and refreshed longer

Lasting relief; soothing comfort

Formulated to shield eyes from dry eye discomfort

Please read all label information on delivery

Muro 128 Eye Drops, Temporary Relief For Corneal Edema, 5% Solution, 0.5 Fl Oz

MURO 128
BAU027715
1.63 X 1.06 X 3.50 Inches
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
SaraGu BH 6.57

Features

15 ml of muro 128

Doctor recommended

Directions : Instill 1 or 2 drops in the affected eye(s) every 3 or 4 hours, or as directed

Store upright at 15°–25°C (59°–77°F)

Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile

REFRESH
92056
3.60 X 1.90 X 1.00 Inches
0.03 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Original strength gel formula

Relieves dry, burning, irritated eyes

Alleviates discomfort

Keeps eyes feeling better longer

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun

#TOP10
Best For Box

Eye Drops By Bausch & Lomb, Lubricant Relief For Dry Eyes, Preservative Free, Single Use Dispensers, 0.6 Ml, 28 Count (Pack Of 2)

SOOTHE
622219_OB
4.20 X 3.20 X 4.70 Inches
0.15 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
VerSure 9.98

Features

LONG LASTING, FAST RELIEF DRY EYE THERAPY: Use Soothe Lubricant Eye Drops to help moisturize & refresh dry eyes for long-lasting relief & comfort Formulated to relieve dryness of the eye & help prevent irritation

DRY EYE DROPS: Tear replacement drops are important to help relieve dry eye symptoms. Inactive Ingredients are boric acid, hydroxyalkylphosphonate, purified water, sodium alginate, sodium borate

BAUSCH + LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops

EYE CARE EXPERTS: For over 150 years, Bausch + Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more

EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to make sure your eyes feel healthy, moisturized, & protected

Systane Lubricant Eye Gel, Nighttime, 0.35-Ounces (Package May Vary)

SYSTANE
65047401
1.25 X 1.25 X 3.75 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

#1 Dr Recommended Brand of Artificial Tears*

Thickest gel formulation to coat the eye with a strong layer of dry eye symptom protection.

Provides long-lasting, nighttime protection while you sleep.

For the temporary relief of burning and irritation due to dryness of the eye

#TOP12

Refresh Lacri-Lube Lubricant Eye Ointment, Nighttime Relief, 0.12 Oz Sterile

REFRESH
93445
3.20 X 1.40 X 0.90 Inches
0.01 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Nighttime relief for intense eye dryness

Soothes eyes while you sleep

Protects eyes from nighttime dryness due to exposure

Ideal for use at bedtime

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Bausch + Lomb Soothe Preservative-Free Lubricant Eye Drops, Xtra Protection, Box Of 30 Single Use Dispensers

SOOTHE
11-IPLQ-8OZF
2.95 X 2.17 X 4.72 Inches
0.15 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

EXTRA PROTECTION FOR DRY EYES: Soothe XP Preservative Free Eye Drops do what ordinary eye drops (non-lipid containing) can't This formula helps restore the eyes lipid layer for relief that lasts, but is preservative free for sensitive eyes

DIFFERENT THAN ARTIFICIAL TEARS: MGD, which often includes breakdown of the lipid layer, is the main cause of evaporative dry eye Soothe XP Dry Eye Drops help restore the lipid layer to seal in moisture & protect against further irritation

BAUSCH and LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops

EYE CARE EXPERTS: For over 150 years, Bausch and Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more

EYE DROPS & MORE: Bausch and Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to make sure your eyes feel healthy, moisturized, & protected

Refresh P.m. Lubricant Eye Ointment, Nighttime Relief, Preservative-Free, 0.12 Oz Sterile, Packaging May Vary

REFRESH
95761
2.80 X 0.90 X 3.30 inches
0.01 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Nighttime relief for intense eye dryness

Preservative-free

Soothes eyes while you sleep

Protects eyes from nighttime dryness due to exposure

Ideal for use at bedtime

Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Eye Ointment By Bausch & Lomb, Lubricant Relief For Dry Eyes, 3.5 G

SOOTHE
AB31336
0.01 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Vitabox 9.88

Features

Soothing nighttime dry eye relief

Contains no preservatives

Gentle enough to use as often as needed

Remove contact lenses before using

#TOP16

Similasan Stye Eye Relief Drops, 0.33 Fl Ounce

SIMILASAN
60094841300544
1.38 X 1.63 X 4.25 inches
0.09 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Similasan Stye Eye Relief drops provide temporary relief from styles (redness, burning, tearing). Homeopathic ingredients stimulate your body's natural defenses instead of masking the symptoms.

Made with natural active ingredients, not harsh chemicals. Unlike mainstream eye drops, Similasan does not contain benzalkonium chloride preservative. Use Similasan as often as you need.

No harsh vasoconstrictors. Gluten and dairy free.

Trusted by pharmacists and families in Switzerland for over 35 years, Similasan is a leading Swiss brand of remedies that uses natural active ingredients instead of harsh chemicals to keep families healthy.

#TOP17

Bausch & Lomb Soothe Lubricant Eye Ointment Night Time 3.50 G (Pack Of 3)

BAUSCH & LOMB
PPAX1227375
12.00 X 8.00 X 5.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Health Savings 9.92

Features

OINTMENT: Soothe Lubricant Eye Ointment offers overnight relief from symptoms associated with severely dry eyes Two lubricants help relieve dryness and protect against irritation

DESIGNED: To be a tear replacement drops; Important to help relieve dry eye symptoms

EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating and preservative-free eye drops

EYE CARE EXPERTS: For over 150 years, Bausch + Lomb has focused on innovation and quality in eye care products, from contact lenses and solutions to eye drops, ointments, eye vitamins and more

EYE CARE PRODUCTS: Can be trusted, from contact lens solution to eye drops, vitamins, and ointments to make sure your eyes feel healthy, moisturized, and protected

Biotrue Hydration Boost Eye Drops For Irritated, Dry Eyes In Single Dose Vials From Bausch + Lomb, Instant Moisture, Preservative Free, Ph Balanced, Naturally Inspired, Pack Of 30 Vials

BIOTRUE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost for Dry Eyes are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.

INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.

Convenient, single dose vials

BIOTRUE EYE DROPS: Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced for comfort.

EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to help your eyes feel moisturized and protected.

#TOP19

Stye Sterile Lubricant Eye Ointment, Ophthalmologist Tested, 0.125 Ounces

STYE
323800
3.00 X 1.04 X 3.31 Inches
0.02 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

Temporarily relieves discomfort due to minor irritations including burning, stinging, and itching in the eye

#1 brand in stye treatment relief; Ophthalmologist tested and clinically proven for multi-symptom relief

To use, pull down the lower lid of the affected eye, apply a small amount of ointment to the inside of the eyelid

Dual-action formula provides symptomatic stye relief and lubrication to help prevent further irritation of the eye

FSA/HSA eligible item in the USA

Systane Nighttime Lubricant Eye Ointment 3.5G Tube

SYSTANE
0065050939
6.00 X 5.00 X 4.00 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

#1 Dr Recommended Brand of Artificial Tears*

Provides nighttime relief of dry eye symptoms

Ointment soothes and protects against dry, irritated eyes

Forms long-lasting, protective layer on eyes while you sleep

Safe, preservative-free formula

Octiq Lubricant Eye Drops For Dry Eyes, Dry Eye Symptom Reliever (Twin Pack 2X 15 Ml Bottles)

OCTIQ
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Aytu Consumer Health 9.95

Features

OPTIC REFRESHMENT: Octiq drops moisturize and replenish the corneal surface, allowing the eyelids to glide smoothly over the eyes. It facilitates comfort for red eyes, itchy eyes, and sore eyes.

HIGH QUALITY: Octiq contains 0.3% hypromellose and cetrimide that act as tear substitutes for dry eyes. Hypromellose helps the eye remain lubricated and produces high quality artificial tears.

HYDRATION: Designed to hydrate and soothe dry eyes. These eye drops for red eyes are gentle, convenient and non-irritating.

LUBRICATING EYE DROPS: Oqtic help to provide soothing comfort and long-lasting eye lubricant, keeping your eyes feeling refreshed throughout the day. This exciting advanced formula helps maintain the natural moisture balance in your eyes, providing effective, long lasting dry eye relief for mild to moderate dry eye.

LUBRICATING EYE DROPS: Oqtic help to provide soothing comfort and long-lasting eye lubricant, keeping your eyes feeling refreshed throughout the day. This exciting advanced formula helps maintain the natural moisture balance in your eyes, providing effective, long lasting dry eye relief for mild to moderate dry eye.

Total Relief Products Blur Relief (Homepathic) Eye Drops (0.5Oz) 15Ml

TOTAL RELIEF PRODUCTS
4.53 X 1.81 X 0.94 Inches
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Cozy Farm 9.06

Features

Total Relief Products Blur Relief Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.

100 Percent Natural and Total Relief Blur Relief Eye Drops can be applied while wearing soft contact lenses.

Homeopathic and For dry, irritated eyes due to screen and environmental stressors.

Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced.

From contact lens solution to eye drops, vitamins, & ointments to help your eyes feel moisturized and protected.

Can-C Lubricant Eye Drops With Antioxidant N-Acetylcarnosine | Effective Solution For Cataracts & Dry Eyes | Natural Eyedrop Ointment Also Includes Peermax Drop Direct Eye Drop Guide For Lens

PEERMAX
860004907039
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
The Highest Quality Ever 6.35

Features

✅ ONLY PATENTED NAC EYE DROPS FOR EYE REPAIRS: Can-C are the only eye drops that use the exact formula used in both the animal and human trials. This non-prescription eye-lubricant is a cost-effective, non-invasive alternative to eye surgery. Plus, every order comes with a handy Eye Drop Guide & Wash Cup!

✅ GREAT FOR A WIDE VARIETY OF EYE ISSUES: Users and scientists have reported that the Can-C natural eye treatment is phenomenal for dry eye syndrome, corneal disorders, computer vision syndrome, eye strain, ocular inflammation, blurred vision, and other systemic diseases, also a benefit for those who wear contact lenses.

✅ USE FOR PREVENTATIVE AND ON-GOING MAINTENANCE: As a preventative measure, two drops into both eyes once a day may be a suitable on-going regime. As for treatment, two drops into the affected eye twice daily is the ideal regime - there is no benefit in exceeding this dose. It is recommended that occasional use of N-acetyl eye-drops continue even after the reduction.

✅ YOU'LL START TO SEE RESULTS QUICKLY: Can-C multipurpose eyedrops have been shown to have measurable affects within only 1-month use, but for maximum efficacy, it is recommended that administration continues for 3-5 months. N-acetyl works best the sooner it is used after an eye problem is detected.

✅ ADMINISTERING THE DROPS JUST GOT EASIER: Do you have a little difficulty using eye drops? We have the solution. These bottles of Can-C come with an Eye Drop Guide that gently holds your eyelid open and directs the drops straight in. It's the simplest way to administer Can-C. We also included a wash cup for the lens.

Optase Hylo Relief Dry Eye Drops - Fast-Acting Preservative Free Eye Drops For Dry Eyes - With Patented Hylo Delivery System - Artificial Tears For Mild To Moderate Dry Eye Relief - .33 Oz, 300 Doses

OPTASE
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Scope Eyecare 9.96

Features

PRESERVATIVE AND PHOSPHATE FREE FORMULA - Made with moisturizing hyaluronic acid and glycerin, OPTASE HYLO Relief uses a phosphate and preservative free artificial tears formula for dry eye relief

NO WASTED EYE DROPS - The innovative, one-click, multi-use bottle of OPTASE HYLO Relief dry eyes eye drops provides 300 calibrated doses, while maintaining sterility for 6 months after opening

MILD TO MODERATE DRY EYE RELIEF - OPTASE HYLO Relief drops provides comfortable relief from mild to moderate dry eye symptoms. Plus, it is contact lens safe for convenient use throughout the day

INNOVATIVE BOTTLE DESIGN – OPTASE HYLO Relief’s unique bottle technology releases one drop of lubricating eye drops with just a press, with no waste – simply grip, position, and click

PAIR WITH OPTASE HYLO NIGHT – For optimal results, use OPTASE HYLO Relief moisturizing eye drops with OPTASE HYLO Relief Nighttime Eye Gel as part of the complete line of expert dry eye relief

Theratears Dry Eye Therapy Eye Drops For Dry Eyes, 0.5 Fl Oz

THERATEARS
CTX
3.80 X 1.90 X 1.00 Inches
0.06 Pounds
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68

Features

TheraTears Dry Eye Therapy - Lubricant Eye Drops provide immediate, long lasting relief of dry eye symptoms

Restores Eyes Natural Balance

Unique hypotonic and electrolyte balanced formula replicates healthy tears

Preservative free in the eye

Convenient, multi-use bottle

Top 10 eye drops ointments Brands on Amazon

Here is the list of top-rated brands that were evaluated by PM.

Brand Count
Refresh 7
Systane 7
Soothe 5
Opcon-A 2
Stye 2
Alaway 1
Bausch & Lomb 1
Biotrue 1
Genteal 1
Lumify 1

Top 10 eye drops ointments Brands Pie Chart


We've carried out a comprehensive analysis of 253,656 reviews on eye drops ointments, using our selection criteria to identify the best options in the categories. Our findings reveal that most customers typically select eye drops ointments priced around $16.82, with top brands including agepha, lumify, optase, refresh, systane, soothe, theratears, similasan and alaway and trp the relief products

Our team of expert editors reviewed these high-quality items and handpicked the top 25 eye drops ointments for your consideration. We've also done extensive research on numerous sellers, identifying the best ones in the categories category. These include agepha, amazon.com, scope eyecare, vitabox, health hut nutrition, the relief products, bp medical supplies, jjbookit and barginhousedeals and buy wise from us .

We are dedicated to assisting our users in finding the right drops Products based on their needs, saving them considerable time when choosing which eye drops ointments to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.